Inhibition of Succinic Dehydrogenase and F0F1-ATP Synthase by 4,4’-Diisothiocyanatostilbene-2,2’-disuIfonic Acid (DIDS)

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 52, Issue 11-12, 1997, Pages 799-806

  Bernardesa, Celene F ^a   Vercesia, Anibai E ^a   Meyer Fernandes, José R ^b   Martins, Orlando B ^b  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ENZYME INHIBITOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; SUCCINATE DEHYDROGENASE;

ANIMAL; ARTICLE; CATTLE; DRUG ANTAGONISM; ENZYMOLOGY; HEART MITOCHONDRION; ISOLATION AND PURIFICATION; KINETICS; LIVER MITOCHONDRION; OXYGEN CONSUMPTION; RAT; SUBMITOCHONDRIAL PARTICLE; WISTAR RAT;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; ANIMALS; CATTLE; ENZYME INHIBITORS; KINETICS; MITOCHONDRIA, HEART; MITOCHONDRIA, LIVER; OXYGEN CONSUMPTION; PROTON-TRANSLOCATING ATPASES; RATS; RATS, WISTAR; SUBMITOCHONDRIAL PARTICLES; SUCCINATE DEHYDROGENASE;

EID: 0031277799     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-1997-11-1212     Document Type: Article

References (38)

1. Aggeler R. and Capaldi, R. A. (1996), Nucleotide -dependent movement of the e subunit between a and β subunits in the Escherichia coli F1F0-type ATPase. Biol. Chem. 271, 13888-13891.
2. Bennett A. B. and Spanswick R. M. (1983), Optical measurements of ApH and ΔØ in corn root membrane vesicles: Kinetic analysis of Cl” effects on a proton- translocating ATPase. J. Membr. Biol. 71, 95-107.
3. 2+-dependent permeabilization of inner mitochondrial membrane by 4,4′diisothiocyanatostilbene-2,2′disulfonic acid (DIDS). Biochim. Biophys. Acta 1188, 93-100.
4. Birch-Machin M. A., Farnsworth L., Ackrell B. A. C., Cochran B., Jackson S., Bindoff L. A., Aitken A., Diamond A. G. and Turnbull D. M. (1992), The sequence of the flavoprotein subunit of bovine heart succinate dehydrogenase. J. Biol. Chem. 267, 11553-11558.
5. Cabantchik Z. I., Knauf P. A. and Rothstein A. (1978), The anion transport system of the red blood cell. The role of membrane protein evaluated by the use of probes. Biochim. Biophys. Acta 515, 239-302.
6. Campbell K. P. and McLennan D. H. (1980), DIDS inhibition of sarcoplasmic reticulum anion efflux and calcium transport. Ann. N. Y. Acad. Sci. 358, 328-331.
7. +- pumping ATPase in membrane vesicles from oat roots. Plant Physiol. 71, 610-617.
8. de Meis L. (1984), Pyrophosphate of high and low energy. J. Biol. Chem. 259, 6090-6097.
9. Denicola A., Rubbo H., Rodrigues D. and Radi R. (1993), Peroxynitrite-mediated cytoxicity to Trypanosoma cruzi. Arch. Biochem. Biophys. 304, 279-286.
10. 32P-labelled Adenosine triphosphate of high specific activity. Biochem. J. 90, 147-149.
11. Gomez-Puyou M. T., Ayala G., Darszon A. and Gomez- Puyou A. (1984), Oxidative Phosphorylation and the Pi - ATP exchange reaction of submitochondrial particles under the influence of organic solvents. J. Biol. Chem. 259, 9472-9478.
12. Grüber G. and Capaldi R. A. (1996), The trapping of different conformations of the Escherichia coli F1 ATPase by disulfide bond formation. J. Biol. Chem. 271, 32623-32628.
13. 2+) ATPase from kidney proximal tubules. Biochemistry 30, 5700-5706.
14. Hatefi Y. (1985), The mitochondrial electron transport and oxidative phosphorylation system. Annu. Rev. Biochem. 54, 1015-1069.
15. Haughton M. A. and Capaldi R. A. (1995), Asymmetry of Escherichia coli F1-type ATPase as a function of the interaction of a-β subunit pairs with the γ and s subunits. J. Biol. Chem. 270, 20568-20574.
16. Kasahara M. and Penefsky H. S. (1978), High affinity binding of monovalent Pi by beef heart mitochondrial adenosine triphosphate. J. Biol. Chem. 253, 4180-4187.
17. Kasai M. and Taguchi T. (1981), Inhibition of anion permeability of sarcoplasmic reticulum vesicles by stilbene derivates and the identification of an inhibitor- binding protein. Biochim. Biophys. Acta 643, 213-219.
18. Kenney W. C. (1975), The reaction of N-Ethylmaleimide at the active site of Succinate dehydrogenase. J. Biol. Chem. 250, 3089-3094.
19. Lee C.-P. and Ernster L. (1967), Energy-coupling in non- phosphorylating submitochondrial particles. Methods Enzymol. 10, 543-548.
20. Leptke S., Fasold H., Pring M. and Passow H. (1976), A study of the relationship between inhibition of anion exchange and binding to the red cell membrane of 4,4′diisothiocyanatostilbene-2,2′disulfonic acid (DIDS) and its dihydroderivative (FLDIDS). J. Membr. Biol. 29, 147-177.
21. Lin W. (1981), Inhibition of anion transport in corn root protoplasts. Plant Physiol. 68, 435-438.
22. Löw H. and Vallin I. (1963), Succinate-linked diphos- phopyridine nucleotide reduction in submitochondrial particles. Biochim. Biophys. Acta 69, 361-374.
23. Lowry O. H., Rosebrough N. J., Farr A. L. and Randall R. J. (1951), Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265-275.
24. Munday R. (1989), Toxicity of thiols and disulphides: involvement of free radical species. Free Rad. Biol. & Med 7, 659-673.
25. Pedemonte C. H. and Kaplan J. H. (1988), Inhibition and derivatization of the renal Na,K-ATPase by dihydro-4,4′diisothiocyanatostilbene-2,2′disulfonate. Biochemistry 27, 7966-7973.
26. Pedemonte C. H. and Kaplan J. H. (1990), Chemical modification as an aproach to elucidation of sodium pump structurefunction relations. Am. J. Physiol. 258, C1-C23.
27. 2+pump revealed by disulfonic stilbenes. J. Membr. Biol. 101, 237-246.
28. Stone D. K., Xiao-Song X. and Racher E. (1984), Inhibition of clathrin-coated vesicle acidification by dura- mycin. J. Biol. Chem. 259, 2701-2703.
29. Tuena de Gómes-Puyou M. and Gómes-Puyou A. (1977), A simple method of purification of a soluble oligomycin-insensitive mitochondrial ATPase. Arch. Biochem. Biophys. 182, 82-86.
30. Veeger C., Dervartanian D. V. and Zeylemaker W. P. (1969), Succinate dehydrogenase. Methods Enzymol. 13, 81-83.
31. 32P] Pi exchange and net ATP synthesis catalyzed by bovine submitochondrial particles. Biochim. Biophys. Acta 1020, 101-106.
32. 2+-ATPase from kidney proximal tubules. J. Biol. Chem. 266, 10324-10330.
33. 2+pump by phosphate. J. Biol. Chem. 256, 415-419.
34. Waisman D. M., Smallwood J., Lafreniere D. and Rasmussen H. (1982), The role of band III in calcium transport across the human erythrocyte membrane. FEBS Lett. 145, 337-340.
35. Xiao-Song X., Stone D. K. and Racher E. (1983), Deter-minants of clathrin-coated vesicle acidification. J. Biol. Chem. 258, 14834-14838.
36. Yagi T. and Hatefi Y. (1984), Thiols in oxidative phosphorylation: Inhibition and energy-potentiated un- clouping by monothiol and dithiol modifiers. Biochemistry 23, 2449-2455.
37. Zaki L., Fasold H., Schuhmann D. and Passow H. (1975), Chemical modification of membrane proteins in relation to inhibition of anion exchange in human red blood cells. J. Cell. Physiol. 86, 471-494.
38. ()and F1 subunits in the gating and coupling fucntion of mitochondrial H+-synthase. The effect of dithiol reagents. Eur. J. Biochem. 208, 9-16.