Molecular basis for thymidine modulation of the efficacy and toxicity of alkylating agents

Pharmacology and Therapeutics

Volumn 76, Issue 1-3, 1997, Pages 101-116

  Hwu, Wen Jen Poo ^a   Mozdziesz, Diane E ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE CANCER CENTER   (United States)

Author keywords

1,3 bis(2 chloroethyl) 1 nitrosourea (BCNU); Antitumor response; Biomodulator; Chemotherapy toxicity; Dacarbazine (DTIC); Thymidine

Indexed keywords

ALKYLATING AGENT; CARMUSTINE; DACARBAZINE; IDOXURIDINE; NITROSOUREA DERIVATIVE; THYMIDINE; THYMIDINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; CLINICAL TRIAL; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; IMMUNOMODULATION; LEUKEMIA; LEUKEMIA L 1210; LEUKEMIA P 388; MELANOMA; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CLINICAL TRIALS; DRUG DESIGN; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; HUMANS; NEOPLASMS; NEOPLASMS, EXPERIMENTAL; THYMIDINE;

EID: 0031277598     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(97)00087-9     Document Type: Review

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