Transformation of chloramphenicol palmitate from therapeutically inactive polymorph A to active polymorph B: Identification and determination of modification A in modification B by DSC

Journal of Thermal Analysis

Volumn 50, Issue 5-6, 1997, Pages 867-871

  Csakurda Harmathy, Zs ^a   Konkoly Thege, I ^a  

^a EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

Chloramphenicol palmitate polymorphs; Cyclic heat treatment; Polymorph impurity

Indexed keywords

CHEMICAL MODIFICATION; CRYSTAL IMPURITIES; DIFFERENTIAL SCANNING CALORIMETRY; PHASE TRANSITIONS; THERMAL CYCLING;

BIOEFFECTIVITY; CHLORAMPHENICOL PALMITATE; POLYMORPHS;

ANTIBIOTICS;

EID: 0031274777     PISSN: 03684466     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (8)

1. A Burger, Sci. Pharm., 45 (1977) 269.
2. A. Burger and R. Ramberger, Mikrochim. Acta II., (1979) 259.
3. M. Otsuka and N. Kaneniwa, J. Pharm. Sci., 75 (1986) 5.
4. M. M. De Villiers, J. G. van der Watt, A. P. Lötter, Drug Develop. Ind. Pharm., 17 (1991) 1295.
5. The United States Pharmacopoeia (USP 23) Rockville 1995, p. 338.
6. British Pharmacopoeia II. London 1993, p. 823.
7. Pharmacopoeia Hungarica VII. Medicina, 1986.
8. V. Ferioli, G. Gamberini, R. Cameroni, Farmaco Ed. Prot., 29 (1974) 309.