Purification of docosahexaenoic acid from tuna oil by a two-step enzymatic method: Hydrolysis and selective esterification

JAOCS, Journal of the American Oil Chemists' Society

Volumn 74, Issue 11, 1997, Pages 1441-1446

  Shimada, Yuji ^a   Maruyama, Kazuaki ^b   Sugihara, Akio ^a   Moriyama, Shigeru ^b   Tominaga, Yoshio ^a  

^a OSAKA MUNICIPAL TECHNICAL RESEARCH INSTITUTE   (Japan)

^b Maruha Nichiro Holdings Inc   (Japan)

Author keywords

Docosahexaenoic acid; Hydrolysis; Lipase; Pseudomonas sp; Rhizopus delemar; Selective esterification; Tuna oil

Indexed keywords

PSEUDOMONAS; PSEUDOMONAS SP.; RHIZOPUS; RHIZOPUS ORYZAE; SCOMBRIDAE GEN. SP.;

CATALYST ACTIVITY; CATALYST SELECTIVITY; ENZYMES; ESTERIFICATION; HYDROLYSIS; PURIFICATION;

DOCOSAHEXAENOIC ACID; LIPASE;

FATTY ACIDS;

EID: 0031272613     PISSN: 0003021X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11746-997-0251-5     Document Type: Article

References (16)

1. Fischer, S., Dietary Polyunsaturated Fatty Acids and Eicosanoid Formation in Humans, in Advances in Lipid Research, edited by R. Paoletti and D. Kritchevsky, Academic Press, New York, 1989, Vol. 23, pp. 169-198.
2. Harris, W.S., Fish Oils and Plasma Lipid and Lipoprotein Metabolism in Humans: A Critical Review, J. Lipid Res. 30:785-809 (1989).
3. Yamaguchi, M., I. Tanaka, and Y. Ohtsu, New Method for Separation and Purification of Polyunsaturated Fatty Acids Using a Silver Ion-Exchanged Spherical Clay Mineral, Yukagaku (in Japanese) 40:959-964 (1991).
4. Shimada, Y., A. Sugihara, K. Maruyama, T. Nagao, S. Nakayama, H. Nakano, and Y. Tominaga, Enrichment of Arachidonic Acid: Selective Hydrolysis of a Single-Cell Oil from Mortierella with Candida cylindracea Lipase, J. Am. Oil Chem. Soc. 72:1323-1327 (1995).
5. Shimada, Y., A. Sugihara, H. Nakano, T. Nagao, M. Suenaga, S. Nakai, and Y. Tominaga, Fatty Acid Specificity of Rhizopus delemar Lipase in Acidolysis, J. Ferment. Bioeng. 83:321-327 (1997).
6. Yang, L.Y., A. Kuksis, and J.J. Myher, Lipolysis of Menhaden Oil Triacylglycerols and the Corresponding Fatty Acid Alkyl Esters by Pancreatic Lipase in vitro: A Reexamination, J. Lipid Res. 31:137-148 (1990).
7. Shimada, Y., K. Maruyama, S. Okazaki, M. Nakayama, A. Sugihara, and Y. Tominaga, Enrichment of Polyunsaturated Fatty Acids with Geotrichum candidum Lipase, J. Am. Oil Chem. Soc. 71:951-954 (1994).
8. Shimada, Y., K. Maruyama, M. Nakamura, S. Nakayama, A. Sugihara, and Y. Tominaga, Selective Hydrolysis of Polyunsaturated Fatty Acid-Containing Oil with Geotrichum candidum Lipase, Ibid. 72:1577-1581 (1995).
9. Hoshino, T., T. Yamane, and S. Shimizu, Selective Hydrolysis of Fish Oil by Lipase to Concentrate n-3 Polyunsaturated Fatty Acids, Agric. Biol. Chem. 54:1459-1467 (1990).
10. Syed Rahmatullah, M.S.K., V.K.S. Shukla, and K.D. Mukherjee, Enrichment of γ-Linolenic Acid from Evening Primrose Oil and Borage Oil via Lipase-Catalyzed Hydrolysis, J. Am. Oil Chem. Soc. 71:569-573 (1994).
11. Hills, M.J., I. Kiewitt, and K.D. Mukherjee. Enzyme Fractionation of Fatty Acids: Enrichment of γ-Linolenic Acid and Docosahexaenoic Acid by Selective Esterification Catalyzed by Lipases, Ibid. 67:561-564 (1990).
12. Syed Rahmatullah, M.S.K., V.K.S. Shukla, and K.D. Mukherjee, γ-Linolenic Acid Concentrates from Borage and Evening Primrose Oil Fatty Acids via Lipase-Catalyzed Esterification, Ibid. 71:563-567 (1994).
13. Foglia, T.A., and P.E. Sonnet, Fatty Acid Selectivity of Lipases: γ-Linolenic Acid from Borage Oil, Ibid. 72:417-420 (1995).
14. Shimada, Y., A. Sugihara, H. Nakano, T. Kuramoto, T. Nagao, M. Gemba, and Y. Tominaga, Purification of Docosahexaenoic Acid by Selective Esterification of Fatty Acids from Tuna Oil with Rhizopus delemar Lipase, Ibid. 74:97-101 (1997).
15. Sugihara, A., Y. Shimada, and Y. Tominaga, Separation and Characterization of Two Molecular Forms of Geotrichum candidum Lipase, J. Biochem. 107:426-430 (1990).
16. Maruyama, K., and M. Nishikawa, Function of Fish Oil and Its Application to Foods, Food Chemicals (in Japanese) 19954:31-37 (1995).