Genetic Transfer of the Wobbler Gene to a C57BL/6J x NZB Hybrid Stock: Natural History of the Motor Neuron Disease and Response to CNTF and BDNF Cotreatment

Experimental Neurology

Volumn 148, Issue 1, 1997, Pages 247-255

  Ishiyama, Takeo ^a   Klinkosz, Bogdan ^a   Pioro, Erik P ^a   Mitsumoto, Hiroshi ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; NERVE PROTEIN;

ANIMAL; ARTICLE; C57BL MOUSE; CELL VACUOLE; DISEASE COURSE; DISEASE MODEL; DRUG COMBINATION; DRUG SCREENING; FEMALE; GENETICS; GENOTYPE; HYBRIDIZATION; MALE; MOTOR NEURON DISEASE; MOUSE; MOUSE MUTANT; MYELINATED NERVE; NERVE DEGENERATION; NEUROLOGIC EXAMINATION; NEW ZEALAND BLACK MOUSE; PATHOLOGY; PHENOTYPE; POLYMERASE CHAIN REACTION; RECESSIVE GENE; SPINAL CORD;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DRUG EVALUATION, PRECLINICAL; DRUG THERAPY, COMBINATION; FEMALE; GENES, RECESSIVE; GENOTYPE; HYBRIDIZATION, GENETIC; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NZB; MICE, NEUROLOGIC MUTANTS; MOTOR NEURON DISEASE; NERVE DEGENERATION; NERVE FIBERS, MYELINATED; NERVE TISSUE PROTEINS; NEUROLOGIC EXAMINATION; PHENOTYPE; POLYMERASE CHAIN REACTION; SPINAL CORD; VACUOLES;

EID: 0031265936     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1997.6643     Document Type: Article

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