Association between plasma vitamin E concentration and the risk of equine motor neuron disease

Veterinary Journal

Volumn 154, Issue 3, 1997, Pages 203-213

  De La Rua Domenech R ^a   Mohammed, H O ^a   Cummings, J F ^a   Divers, T J ^a   De Lahunta, A ^a   Summers, B A ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Horse; Motor neuron; Risk factors; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL;

ALPHA TOCOPHEROL DEFICIENCY; ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; BREEDING; CASE CONTROL STUDY; DIET; FEMALE; HORSE; HORSE DISEASE; MALE; MOTOR NEURON DISEASE; PHYSIOLOGY; RISK FACTOR;

ANIMALS; BREEDING; CASE-CONTROL STUDIES; DIET; FEMALE; HORSE DISEASES; HORSES; MALE; MOTOR NEURON DISEASE; RISK FACTORS; VITAMIN E; VITAMIN E DEFICIENCY;

EID: 0031265111     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1090-0233(97)80021-4     Document Type: Review

References (49)

1. BAUMGARTNER, W., FRESE, K. & ELMADFA, I. (1990). Neuroaxonal dystrophy associated with vitamin E deficiency in two Haflinger horses. Journal of Comparative Pathology 103, 114-19.
2. BLACKLEY, B. R. & BELL, R. J. (1994). The vitamin A and vitamin E status of horses raised in Alberta and Saskatchewan. Canadian Veterinary Journal 35, 297-300.
3. BLYTHE, L. L., CRAIG, A. M., LASSEN, E. D., ROWE, K. E. & APPELL, L. H. (1991). Serially determined plasma α-tocopherol concentrations and results of the oral vitamin E absorption test in clinically normal horses and in horses with degenerative myeloencephalopathy. American Journal of Veterinary Research 52, 908-11.
4. BLYTHE, L. L. & CRAIG, A. M. (1992). Equine degenerative myeloencephalopathy. Compendium on Continuing Education for the Practicing Veterinarian 14, 1215-21-1633-36.
5. BROWN, R. H. (1995). Amyotrophic lateral sclerosis: recent insights form genetics and transgenic mice. Cell 80, 687-92.
6. CRAIG, A. M., BLYTHE, L. L., LASSEN, E. D., ROWE, K. E., BARRINGTON, R. & SLIZESKI, M. (1989). Variations of serum vitamin E, cholesterol, and total serum lipid concentrations in horses during a 72-hour period. American Journal of Veterinary Research 50, 1527-31.
7. CUMMINGS, J. F., DE LAHUNTA, A., GEORGE, C. et al. (1990). Equine motor neuron disease: a preliminary report. Cornell Veterinarian 80, 357-79.
8. CUMMINGS, J. F., DE LAHUNTA, A., MOHAMMED, H. O. et al. (1991). Equine motor neuron disease: a new neurologic disorder. Equine Practice 13, 15-8.
9. CUMMINGS, J. F., DE LAHUNTA, A., MOHAMMED, H. O. et al. (1995). Endothelial lipopigment as an indicator of α-tocopheral deficiency in two equine neurodegenerative disorders. Acta Neuropathologica 90, 266-72.
10. DE LA RÚA-DOMÈNECH, R., MOHAMMED, H. O., ATWILL, E. R. et al. (1995a). Epidemiologic evidence for clustering of EMND in the United States. American Journal of Veterinary Research 11, 1433-39.
11. DE LA RÚA-DOMÈNECH, R., MOHAMMED, H. O., CUMMINGS, J. F. et al. (1995b). Incidence and risk factors of equine motor neuron disease: an ambidirectional study. Neuroepidemiology 14, 54-64.
12. DE LA RÚA-DOMÈNECH, R., MOHAMMED, H. O., CUMMINGS, J. F., DIVERS, T. J., DE LAHUNTA, A. & SUMMERS, B. A. (1996). Intrinsic, management and nutritional factors associated with equine motor neuron disease. Journal of the American Veterinary Medical Association , -(submitted for publication).
13. DENG, H- X., HENTATI, A., TAINER, J. A. et al. (1993). Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 261, 1047-51.
14. DIVERS, T. J., MOHAMMED, H. O., CUMMINGS, J. F. et al. (1992). Equine motor neuron disease: a new cause of weakness, trembling and weight loss. Compendium on Continuing Education for the Practicing Veterinarian 14, 1222-6.
15. DIVERS, T. J., MOHAMMED, H. O., CUMMINGS, J. F. et al. (1994). Equine motor neuron disease: findings in 28 horses and proposal of a pathophysiological mechanism for the disease. Equine Veterinary Journal 26, 409-15.
16. DIXON, W. J. (1992). Stepwise logistic regression. In BMDP statistical software manual, pp. 1105-44. Berkeley, Calif: University of California Press.
17. , DOXEY, D. L., MILNE, E. M., GILMOUR, J. S. & POGSON, D. M. (1991). Clinical and biochemical features of grass sickness (equine dysautonomia). Equine Veterinary Journal 23, 360-64.
18. FATZER, R., STRAUB, R., GERBER, V. et al. (1995). Sind Equine Motorische Nervenzell-Degeneration (EMND) und Graskrankheit des Pferdes unterschiedliche Manifestationen der gleichen Grundkrankheit? Pferdeheilkunde 11, 17-29.
19. GRUYS, E., BEYNEN, A. C., BINKHORST, G. J., VAN DIJK, S., KOEMAN, J. P. & STOLK, P. (1994). Neurodegenerative aandoeningen van het centrale zenuwstelsel bij het paard. Tijdschrift voor Diergeneeskunde 119, 561-67.
20. GURNEY, M. E., CUTTING, F. B., ZHAI, P. et al. (1996). Benefit of vitamin E, riluzole and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Annals of Neurology 39, 147-57.
21. HAHN, C. N. & MAYHEW, I. G. (1993). Does equine motor neuron disease exist in the United Kingdom? Veterinary Record 132, 133-4.
22. HALLIWELL, B. (1992). Reactive oxygen species and the central nervous system. Journal of Neurochem 59, 1609-23.
23. HOSMER, D. W. & LEMESHOW, S. (1989). Applied logistic regression. New York: John Wiley & Sons.
24. JACKSON, C. A., DE LAHUNTA, A., CUMMINGS, J. F. et al. (1996). Spinal accessory nerve biopsy as an ante mortem diagnostic test for equine motor neuron disease. Equine Veterinary Journal 28, 215-19.
25. KLEINBAUM, D. G., KUPPER, L. L. & MORGENSTERN, H. (1982). Epidemiologic research. Principles and quantitative methods. New York: Van Nostrand Reinhold.
26. KUWAMURA, M., IWAKI, M., YAMATE, J., KOTANE, T., SAKUMA, S. & YAMASHITA, A. (1994). The first case of equine motor neuron disease in Japan. Journal of Veterinary Medical Science 56, 195-7.
27. LEMESHOW, S. & HOSMER, D. W. (1982). A review of goodness of fit statistics for use in the development of logistic regression models. American Journal of Epidemiology 115, 92-106.
28. LOFSTED, J. & IKEDE, B. O. (1994). Motor neuron disease in a quarter horse form Nova Scotia. Canadian Veterinary Journal 35, 507-9.
29. MAENPAA, P. H., KOSKINEN, T. & KOSKINEN, E. (1988). Serum profiles of vitamins A, E and D in mares and foals during different seasons. Journal of Animal Science 66, 1418-23.
30. MAYHEW, I. G., BROWN, C. M., STOWE, H. D., TRAPP, A. L., DERKSEN, F. J. & CLEMENT, S. F. (1987). Equine degenerative myeloencephalopathy: a vitamin E deficiency that may be familial. Journal of Veterinary Internal Medicine 1, 45-50.
31. MAYHEW, I. G. (1989). Tetraparesis, paraparesis and ataxia of the limbs, and episodic weakness. In Large animal neurology, pp. 294-6. Philadelphia: Lea & Febiger.
32. MOHAMMED, H. O., CUMMINGS, J. F., DIVERS, T. J. et al. (1993). Risk factors associated with equine motor neuron disease: a possible model for human MND. Neurology 43, 966-71.
33. MOHAMMED, H. O., DE LA RÚA-DOMÈNECH, R., CUMMINGS, J. F., DIVERS, T. J. & DE LAHUNTA, A. (1996). Epidemiologic findings on equine motor neuron disease. Equine Veterinary Journal , -(submitted for publication).
34. NELSON, J. S. (1983). Neuropathological studies of chronic vitamin E deficiency in mammals including humans. In Biology of Vitamin E. London: Pitman Books.
35. PETERSSON, K., HINTZ, H. F., SCHRYVER, H. F. & COMBS, G. F. Jr. (1990). The effect of vitamin E on membrane integrity during submaximal exercise. In Equine Exercise Physiology 3, eds. S. G. B. Persson, A. Lindholm & L. B., pp. 315-22. Davis: ICEEP Publications.
36. PODELL, M., VALENTINE, B. A., CUMMINGS, J. F. et al. (1995). Electromyography in acquired equine motor neuron disease. Progress in Veterinary Neurology 6, 128-34.
37. POLACK, E. W. (1996). Quantitative and toxicological assessment on equine motor neuron disease. Cornell University: Doctoral thesis.
38. PRENDERGAST, M., BASSETT, H. F. & CUMMINGS, J. F. (1994). Equine motor neuron disease (letter). Veterinary Record 135, -146.
39. RIIS, R. C., REBHUN, W. C., JACKSON, C. A. et al. (1995). Fundic lesions in horses affected with equine motor neuron disease (Abstract). Proceedings of the Annual Meeting of the American College of Veterinary Ophthalmologists 26, -23.
40. RONÉUS, B. O., HAKKARAINEN, B. O., LINDHOLM, C. A. & TYÖPPÖNEN, J. T. (1986). Vitamin E requirements of adult Standardised horses evaluated by tissue depletion and repletion. Equine Veterinary Journal 18, 50-8.
41. SAASTAMOINEN, M. T. & JUUSELA, J. (1993). Serum vitamin E concentration in horses on different vitamin E supplementation levels. Acta Agricola Scandinavica, Section A, Animal Science 43, 52-57.
42. SATYA-MURTI, S., HOWARD, L., KROHEL, G. & WOLF, B. (1986). The spectrum of neurologic disorder from vitamin E deficiency. Neurology 36, 917-21.
43. SCHRYVER, H. F. & HINTZ, H. F. (1987). Vitamins. In Current therapy in equine medicine 2, ed. N. E. Robinson, pp. 405-12. Philadelphia: W. B. Saunders Company.
44. SHAW, P. J., INCE, P. G., FALKOUS, G. & MANTLE, D. (1995). Oxidative damage to protein in sporadic motor neuron disease spinal cord. Annals of Neurology 38, 691-95.
45. SIES, H., STAHL, W. & SUNDQUIST, A. R. (1992). Antioxidant functions of vitamins. Vitamins E and C, beta-carotene and other carotenoids. Ann. NY Acad. Sci. 669, 7-20.
46. STEISS, J. E., TRABER, M. G., WILLIAMS, M. A., HAYDEN, H. J. & WRIGHT, J. C. (1994). Alpha tocopherol concentrations in clinically normal adult horses. Equine Veterinary Journal 26, 417-19.
47. SUSTRONCK, B., DEPREZ, P., VAN ROY, M., MUYLLE, E., ROELS, S. & THOONEN, H. (1993). Equine motor neuron disease: the first confirmed cases in Europe. Vlaams Diergeneeskundig Tijdschrift 62, 40-4.
48. TRABER, M. G., SOKOL, R. J., RINGEL, S. P., NEVILLE, H. E., THELLMAN, C. A. & KAYDEN, H. J. (1987). Lack of tocopherol in peripheral nerves of vitamin E-deficient patients with peripheral neuropathy. New England Journal of Medicine 317, 262-5.
49. VALENTINE, B. A., DE LAHUNTA, A., GEORGE, C. et al. (1994). Acquired equine motor neuron disease. Veterinary Pathology 31, 130-8.