Editorial: Immunity and aging

Developmental and Comparative Immunology

Volumn 21, Issue 6, 1997, Pages 455-460

  Wick, G ^a   Grubeck Loebenstein, B ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 2;

AGING; ALZHEIMER DISEASE; ANTIGEN PRESENTATION; ATHEROSCLEROSIS; B LYMPHOCYTE; DIET; HUMAN; IMMUNE RESPONSE; IMMUNITY; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE; THYMUS; AGED; ANIMAL; ARTERIOSCLEROSIS; EDITORIAL; IMMUNOLOGY;

AGED; AGING; ALZHEIMER DISEASE; ANIMALS; ANTIGEN PRESENTATION; ARTERIOSCLEROSIS; B-LYMPHOCYTES; HUMANS; IMMUNITY; T-LYMPHOCYTES;

EID: 0031264439     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-305X(97)00025-6     Document Type: Editorial

References (46)

1. R.A. Miller The aging immune system: Primer and prospectus Science 273 1996 70 74
2. G. Wick B. Grubeck-Loebenstein The aging immune system: Primary and secondary alterations of immune reactivity in the elderly Experimental Gerontology 32 1997 401 413
3. G.J. Ligthart J.X. Corberand C. Fournier P. Galanaud W. Hijmans B. Kennes H.K. Müller-Hermelink G.G. Steinmann Admission criteria for immunogerontological studies in man: The SENIEUR protocol Mechanisms of Ageing and Development 28 1984 47 55
4. G. Reibnegger L.A. Huber D. Schönitzer E.R. Werner H. Wachter G. Wick K.N. Traill Approach to define ‘normal aging’ in man: Immune function, serum lipids, lipoproteins and neopterin levels Mechanisms of Ageing and Development 16 1988 67 82
5. T. Stulnig A. Mair E. Jarosch M. Schober D. Schönitzer G. Wick L.A. Huber NIEUR protocol compatible aged population for immunogerontological studies Mechanisms of Ageing and Development 68 1993 105 115
6. K.N. Traill D. Schönitzer G. Jürgens G. Böck R. Pfeilschifter M. Hilchenbach A. Holasek O. Förster G. Wick Age-related changes in lymphocyte subset proportions, surface differentiation, antigen density and plasma membrane fluidity: Application of the EURAGE SENIEUR protocol admission criteria Mechanisms of Ageing and Development 33 1985 39 66
7. J.E. Nagel R.K. Chopra F.J. Chrest M.T. McCoy E.L. Schneider N.J. Holbrook W.H. Adler Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors Journal of Clinical Investigation 81 1988 1096 1102
8. R. Schnab L.M. Pfeffer P. Szabo D. Gamble C.M. Schnurr M.E. Weksler Defective expression of high affinity IL-2 receptors on activated T cells from aged humans International Immunology 2 1990 239 246
9. R.A. Miller Aging and immune function: Cellular and biochemical analyses Experimental Gerontology 29 1994 21 35
10. L.A. Huber Q. Xu G. Jürgens G. Böck E. Bühler K.F. Gey D. Schönitzer K.N. Traill G. Wick Correlation of lymphocyte lipid composition, membrane microviscosity and mitogen response in the aged European Journal of Immunology 21 1991 2761 2765
11. + T cells in centenarians and in long-term T cell cultures: A possible cause for both in vivo and in vitro immunosenescence Experimental Gerontology 29 1994 601 609
12. R.B. Effros Loss of CD28 expression on T lymphocytes: A marker of replicative senescence Developmental & Comparative Immunology 21 1997 471 478
13. K.M. Rao M.S. Currie J. Padmanabhan H.J. Cohen Age-related alterations in actin cytoskeleton and receptor expression in human leukocytes Journal of Gerontology 47 1992 B37 B44
14. D.A. Gamble R. Schwab M.E. Weksler P. Szabo Decreased steady state c-myc mRNA in activated T cell cultures from old humans is caused by a smaller proportion of T cells that transcribe the c-myc gene Journal of Immunology 144 1990 3569 3573
15. W. Wu M. Pahlavani H.T. Cheung A. Richardson The effect of aging on the expression of interleukin 2 messenger ribonucleic acid Cellular Immunology 100 1986 224 231
16. C. Pieri R. Recchioni F. Moroni F. Marcheselli G. Lipponi Phytohemagglutinin induced changes of membrane lipid packing, c-myc and c-myb encoded protein expression in human lymphocytes during aging Mechanisms of Ageing and Development 64 1992 177 187
17. N.L. Perillo F. Naeim R.L. Walford R.B. Effros In vitro cellular aging in T lymphocyte cultures: Analysis of DNA content and cell size Experimental Cell Research 207 1993 131 135
18. N.L. Perillo R.L. Walford M.A. Newman R.B. Effros Human lymphocytes possess a limited in vitro life span Experimental Gerontology 24 1989 177 187
19. M. McCarron Y. Osborne C.J. Story I.L. Dempsey D.R. Turner A.A. Morley Effect of age on lymphocyte proliferation Mechanisms of Ageing and Development 41 1987 211 218
20. R.L. Walford S.W. Jawaid F. Naeim Evidence for in vitro senescence of T lymphocytes cultured from normal human peripheral blood Age 4 1987 67 71
21. B. Grubeck-Loebenstein H. Lechner K. Trieb Long-term in vitro growth of human T cell clones: Can postmitotic ‘senescent’ cell populations be defined? International Archives of Allergy and Immunology 104 1994 232 239
22. R. Ahmed D. Gray Immunological memory and protective immunity: Understanding their relation Science 272 1996 54 60
23. F.L. Ruben J. Nagel P.P. Fireman 1978 antitoxin responses in the elderly to tetanusdiphtheria in the (Td) immunizations American Journal of Epidemiology 108 1978 145
24. B.E. Stein Vaccinating elderly people: Protecting from avoidable disease Drugs and Ageing 5 1994 242 253
25. R. Glück A. Wegmann Influenza vaccination in the elderly Development & Comparative Immunology 21 1997 501 507
26. D.N. Posnett R. Sinha S. Kabak C. Russo Clonal populations of T cells in normal elderly humans: The T cell equivalent to ‘benign monoclonal gammopathy’ Journal of Experimental Medicine 179 1994 609 618
27. M. De la Fuenta Changes in the macrophage function with aging Comparative Biochemistry and Physiology A 81 1985 935 938
28. V. Vetvicka H. Tlaskalova-Hogenova M. Pospisil Impaired antigen presenting function of macrophages from aged mice Immunological Investigation 14 1985 105 114
29. E.H. Perkins J.M. Masucci P.L. Glover Antigen presentation by peritoneal macrophages from young, adult and old mice Cellular Immunology 70 1982 1 10
30. S. Komatsubara B. Cinader S. Muramatsu Functional competence of dendritic cells of ageing C57/BL/6 mice Scandinavian Journal of Immunology 24 1986 517 525
31. E. Sprecher Y. Becker G. Kraal E. Hall D. Harrison L.D. Schultz Effect of aging on epidermal DC populations in C57BL/6J mice Journal of Investigative Dermatology 99 1990 247 253
32. R. Schwab P.B. Hausman E. Rinnooy-Kan M.E. Weksler Immunological studies of aging X. Impaired T lymphocytes and normal monocyte response from elderly humans to the mitogenic antibodies OKT3 and Leu4 Immunology 55 1985 677 684
33. U. Fagiolo A. Cossarizza E. Scala E. Fanales-Belasio C. Orltolani E. Cozzi D. Monti C. Franceschi R. Paganelli Increased cytokine production in mononuclear cells of healthy elderly people European Journal of Immunology 23 1993 2375 2378
34. I. Beckman K. Dimopoulos X. Xaioning J. Bradley P. Henschke M. Ahern T cell activation in the elderly: Evidence for specific deficiencies in T cell/accessory cell interactions Mechanisms of Ageing and Development 51 1990 265 276
35. E.A. Rich M.A. Mincek K.B. Armitage E.G. Duffy D.C. Owen J.D. Fayen D.L. Hom J.J. Ellner Accessory function and properties of monocytes from healthy elderly humans for T lymphocyte responses to mitogen and antigen Gerontology 39 1993 93 108
36. M.M. Steger C. Maczek B. Grubeck-Loebenstein Morphologically and functionally intact dendritic cells can be derived from the peripheral blood of aged individuals Clinical and Experimental Immunology 105 1996 544 551
37. D. Frasca G. Doria Recombinant cytokines a an approach to immune reconstitution in aging Development & Comparative Immunology 21 1997 525 530
38. J.D. Mountz H.-C. Hsu Clinical features associated with correction of T cell senescence: Increased acute-phase response, amyloidosis and arthritis Development & Comparative Immunology 21 1997 509 523
39. B. Rivnay S. Bergman M. Shinitzky A. Globerson Correlations between membrane viscosity, serum cholesterol, lymphocyte activation and aging in man Mechanisms of Ageing and Development 12 1980 119 126
40. G. Böck L.A. Huber G. Wick K.N. Traill Use of a FACS III for fluorescence depolarization with DPH Journal of Histochemistry and Cytochemistry 37 1989 1653 1658
41. P. Vandenabele W. Fiers Is amyloidogenesis during Alzheimer's disease due to an IL-l/IL-6 mediated acute phase response in the brain? Immunology Today 12 1991 217 219
42. L.M. Shaffer M.D. Dority R. Grupta-Bausal R.C. Frederickson S.G. Younkin K.R. Brunden Amyloid β protein removal by neuroglial cells in culture Neurobiology of Ageing 16 1995 737 745
43. K. Trieb G. Ransmayr R. Sgonc H. Lassmann B. Grubeck-Loebenstein APP peptides stimulate lymphocyte proliferation in normals, but not in patients with Alzheimer's disease Neurobiology of Ageing 17 1996 541 547
44. T. Schmitt E. Steiner P. Klingler A. Sztankay B. Grubeck-Loebenstein The production of an amyloidogenic metabolite of the Alzheimer amyloid β precursor protein (APP) in thyroid cells is stimulated by interleukin Iβ, but inhibited by interferon γ Journal of Clinical Endocrinology & Metabolism 81 1996 1666 1669
45. G. Wick G. Schett A. Amberger R. Kleindienst Q. Xu Is atherosclerosis an immunologically mediated disease? Immunology Today 16 1995 27 33
46. Q. Xu G. Wick The role of heat shock proteins in protection and pathophysiology of the arterial wall Molecular Medicine Today 2 1996 372 379