Arginine Supplementation Increases Weight Gain, Depresses Antibody Production, and Alters Circulating Leukocyte Profiles in Preruminant Calves Without Affecting Plasma Growth Hormone Concentrations

Journal of Animal Science

Volumn 75, Issue 11, 1997, Pages 3019-3025

  Fligger, J M ^a   Gibson, C A ^a   Sordillo, L M ^a   Baumrucker, C R ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Arginine; Calves; Immunity; Leukocytes; Somatotropin

Indexed keywords

ARGININE; GROWTH HORMONE; HEMOCYANIN; IMMUNOGLOBULIN G; KEYHOLE LIMPET HEMOCYANIN; KEYHOLE-LIMPET HEMOCYANIN; NITROGEN; SOMATOMEDIN BINDING PROTEIN 3; UREA;

AGING; ANIMAL; ANIMAL DISEASE; ANTIBODY PRODUCTION; ARTICLE; BLOOD; CATTLE; CYTOLOGY; DIET; DIET SUPPLEMENTATION; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; LEUKOCYTE; MALE; METHODOLOGY; NEWBORN; PHYSIOLOGY; RADIOIMMUNOASSAY; RANDOMIZATION; WEIGHT GAIN;

AGING; ANIMALS; ANIMALS, NEWBORN; ANTIBODY FORMATION; ARGININE; CATTLE; DIET; DIETARY SUPPLEMENTS; GROWTH HORMONE; HEMOCYANIN; IMMUNOGLOBULIN G; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; LEUKOCYTES; MALE; NITROGEN; RADIOIMMUNOASSAY; RANDOM ALLOCATION; UREA; WEIGHT GAIN;

EID: 0031264241     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/1997.75113019x     Document Type: Article

References (39)

1. Alba-Roth, J., O. A. Mauller, J. Schopohl, and K. von Werder. 1988. Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion. J. Clin. Endocrinol. Metab. 67:1186-1189.
2. Barbul, A. 1986. Arginine: Biochemistry physiology and therapeutic implications. J. Parenter. Enteral. Nutr. 10:227-238.
3. Bernasconi, S., C. Volta, A. Cozzini, M. Ziveri, L. Ghizzoni, and C. Panza. 1992. Growth hormone response to growth hormone-releasing hormone (GHRH), insulin, clonidine and arginine after GHRH pretreatment in children. Acta Endocrinol. 126: 105-108.
4. Blum, W. F., K. Albertsson-Wikland, S. Rosberg, and M. B. Ranke. 1993. Serum levels of insulin-like growth factor I (IGF-I) and IGF binding protein 3 reflect spontaneous growth hormone secretion. J. Clin. Endocrinol. Metab. 76:1610-1616.
5. Blum, W. F., and M. B. Ranke. 1990. Use of insulin-like growth factor-binding protein-3 for the evaluation of growth disorders. Horm. Res. 33 (Suppl. 4):31-37.
6. Breier, B. H., P. D. Gluckman, and J. J. Bass. 1988. Plasma concentrations of insulin-like growth factor-I and insulin in the infant calf: ontogeny and influence of altered nutrition. J. Endocrinol. 119:43-50.
7. Chew, B. P., J. R. Eisenman, and T. S. Tanaka. 1984. Arginine infusion stimulates prolactin, growth hormone, insulin and subsequent lactation in pregnant dairy cows. J. Dairy Sci. 67: 2507-2518.
8. Cunningham-Rundles, S. 1993. Preface. In: M. Decker (Ed.) Nutrient Modulation of the Immune Response. p III. Marcel Dekker, New York.
9. Davenport, G. M., J. A. Boling, and K. K. Schillo. 1995. Growth and endocrine responses of lambs fed rumen-protected ornithine and arginine. Small Ruminant Res. 17:229-236.
10. Deaver, D. R. 1995. A new non-isotopic detection system for immunoassays. Nature (Lond.) 377:758-760.
11. Gala, R. R. 1991. Prolactin and growth hormone in the regulation of the immune system. Proc. Soc. Exp. Biol. Med. 198:513-527.
12. Ghigo, E., J. Bellone, E. Mazza, E. Imperiale, M. Procopio, F. Valente, R. Lala, C. DeSanctis, and F. Camanni. 1990. Arginine potentiates the GHRH-but not the pyridostigmine-induced GH secretion in normal short children: Further evidence for a somatostatin-suppressing effect of arginine. Clin. Endocrinol. 32:763-767.
13. Ghigo, E., S. Goffi, E. Mazza, E. Arvat, M. Procopio, and J. Bellone. 1989. Repeated GH-releasing hormone administration unravels different GH secretory patterns in normal adults and children. Acta Endocrinol. 120:598-601.
14. Granger, D. L., J. B. Hibbs, J. R. Perfect, and D. T. Durack. 1988. Specific amino acid (L-arginine) requirement for microbiostatic activity of murine macrophages. J. Clin. Invest. 81: 1129-1136.
15. Granger, D. L., J. B. Hibbs, J. R. Perfect, and D. T. Durack. 1990. Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. J. Clin. Invest. 85:264-273.
16. Grinspoon, S., D. Clemmons, B. Swearingen, and A. Klibanski. 1995. Serum insulin-like growth factor-binding protein-3 levels in the diagnosis of acromegaly. J. Clin. Endocrinol. Metab. 80: 927-932.
17. Kelley, K. W. 1990. The role of growth hormone in modulation of the immune response. Ann. N. Y. Acad. Sci. 594:95-103.
18. Kirk, S. J., and A. Barbul. 1990. Role of arginine in trauma, sepsis and immunity. J. Parenter. Enteral Nutr. 14 (Suppl. 5): 226s-229s.
19. Korver, K., W. P. Zeijlemaker, P. T. Schellekens, and J. M. Vossen. 1984. Measurement of primary in vivo IgM- and IgG-antibody response to KLH in humans: implications of pre-immune IgM binding in antigen-specific ELISA. J. Immunol. Methods 74: 241-251.
20. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.) 227: 680-685.
21. MacDonald, R. D., and D. R. Deaver. 1993. Testicular development in bulls treated with recombinant bovine somatotropin. J. Anim. Sci. 71:1540-1545.
22. Madden, H. P., R. J. Breslin, H. L. Wasserkrug, G. Efron, and A. Barbul. 1988. Stimulation of T cell immunity by arginine enhances survival in peritonitis. J. Surg. Res. 44:658-663.
23. Merriam, G. R., and K. W. Wachter. 1982. Algorithms for the study of episodic hormone secretion. Am. J. Physiol. 243:E310-E318.
24. Norris, K. A., J. E. Schrimpf, J. L. Flynn, and S. M. Morris. 1995. Enhancement of macrophage microbicidal activity: Supplemental arginine and citrulline augment nitric oxide production in murine peritoneal macrophages and promote intracellular killing of Trypanosoma cruzi. Infect. Immun. 63:2793-2796.
25. Pollock, J. M., T. G. Rowan, J. B. Dixon, S. D. Carter, and D. F. Kelly. 1991. Estimation of immunity in the developing calf: Cellular and humoral responses to keyhole limpet haemocyanin. Vet. Immunol. Immunopathol. 29:105-113.
26. Rose, W. C. 1949. The amino acid requirements of man. Fed. Proc. 8: 546-552.
27. Saito, H., O. Trocki, S. L. Wang, S. J. Gonce, S. N. Joffe, and J. W. Alexander. 1987. Metabolic and immune effects of dietary arginine supplementation after burn. Arch. Surg. 122:784-789.
28. Sano, H., S. Nakamura, S. Kobayashi, H. Takahashi, and Y. Terashima. 1995. Effect of cold exposure on profiles of metabolic and endocrine responses and on responses to feeding and arginine injection in sheep. J. Anim. Sci. 73:2054-2062.
29. SAS. 1994. Introductory Comparison of the GLM and Mixed Procedures. SAS Inst. Inc., Cary, NC.
30. Sasaki, Y., H. Takahashi, H. Aso, A. Ohneda, and T. E. Weekes. 1982. Effects of cold exposure on insulin and glucagon secretion in sheep. Endocrinology. 111:2070-2076.
31. Seifter, E., G. Rettura, A. Barbul, and S. M. Levenson. 1978. Arginine: an essential amino acid for injured rats. Surgery 84: 224-230.
32. Skaar, T. C., C. R. Baumrucker, D. R. Deaver, and J. W. Blum. 1994. Diet effects and ontogeny of alterations of circulating insulin-like growth factor binding proteins in newborn dairy calves. J. Anim. Sci. 72:421-427.
33. Takagi, K., I. Nukaya, K. Yasukawa, and Y. Suketa. 1994. Inhibitory mechanisms of antibody production by nitric oxides released from activated macrophages during the immune response: Relationship to energy consumption. Immunol. Cell Biol. 72: 241-248.
34. Vanderkooi, W. K., M. J. Vandehaar, B. K. Sharma, M. Binelli, H. A. Tucker, R. M. Akers, and W. M. Moseley. 1995. Comparison of growth hormone-releasing factor and somatotropin: The somatotropic axis in lactating primiparous cows. J. Dairy Sci. 78:2140-2149.
35. Vezinhet, A. 1968a. Effect of hypophysectomy on the weight gain of the lamb. C. R. Hebd. Seances Acad. Sci. Ser. D. Sci. Nat. 266: 388-390.
36. Vezinhet, A. 1968b. Effect of hypophysectomy on the weight gain of the rabbit. C. R. Hebd. Seances Acad. Sci. Ser. D. Sci. Nat. 266: 2348-2351.
37. Volta, C., S. Bernasconi, L. Lughetti, L. Ghizzoni, M. Rossi, M. Costa, and A. Cozzini. 1995. Growth hormone response to growth hormone-releasing hormone (GHRH), insulin, clonidine and arginine after GHRH pretreatment in obese children: Evidence of somatostatin increase? Eur. J. Endocrinol. 132: 716-721.
38. Williams, A. P., and D. Hewitt. 1979. The amino acid requirements of the preruminant calf. Br. J. Nutr. 41:311-319.
39. Wong, J. M., and T. R. Billiar. 1995. Regulation and function of inducible nitric oxide synthase during sepsis and acute inflammation. In: Nitric Oxide: Biochemistry, Molecular Biology and Therapeutic Implications. p 155. Academic Press, New York.