Clinical study of the antinflammatory activity and gastroenteric tolerability of amtolmetin guacyl, a new nsaid, in comparison with diclofenac in elderly osteoarthritic patients;Studio clinico sull'attività antiinfiammatoria e sulla tollerabilità gastro-enterica di amtolmètineguacil, un nuovo FANS, in confronta a diclofenac su pazienti anziani con patologie osteoarticolari

Clinica Terapeutica

Volumn 148, Issue 11, 1997, Pages 543-548

  Tavella, Antonino ^a,b   Ursini, Giuseppe ^a,b  

^a FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^b NONE   (Italy)

Author keywords

Amtolm tineguacil; Diclofenac; Gastroscopia

Indexed keywords

AMTOLMETIN GUACIL; DICLOFENAC; DRUG DERIVATIVE; GLYCINE; NONSTEROID ANTIINFLAMMATORY AGENT; PYRROLE DERIVATIVE;

AGE; AGED; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; DRUG EFFECT; DRUG TOLERANCE; FEMALE; GASTROSCOPY; HUMAN; INTESTINE MUCOSA; MIDDLE AGED; MONITORING; ORAL DRUG ADMINISTRATION; OSTEOARTHRITIS; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; STOMACH MUCOSA;

ADMINISTRATION, ORAL; AGE FACTORS; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DATA INTERPRETATION, STATISTICAL; DICLOFENAC; DRUG TOLERANCE; FEMALE; GASTRIC MUCOSA; GASTROSCOPY; GLYCINE; HUMANS; INTESTINAL MUCOSA; MIDDLE AGED; MONITORING, PHYSIOLOGIC; OSTEOARTHRITIS; PYRROLES;

EID: 0031262539     PISSN: 00099074     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Gabriel S.E., Jaakkimainen L., Bombardier C.: Risk for serious gastrointestinal complications related to the use of non-steroidal antiinflammatory drugs: meta-analysis. Ann Intern Med 115:787-796, 1991.
2. Fries J.F., Williams C.A., Bloch D.A.: The relative toxicity of non-steroidal anti-inflammatory drugs. Arthritis Rheum. 34; 1353-60, 1991.
3. Zeider H.: Epidemiology of NSAID induced gastropathy. J Rheumatol 18 (supp.); 2-5, 1991.
4. Fries J.F., Williams C.A., Boch D.A., Michel B.A.: Non steroidal anti-inflammatory drug-associated gastropathy:inddence and risk factor models. Am J Med 91; 213-22, 1991.
5. Soll A.H., Weinstein W.M., Kurata J., McCarthy D.: Non steroidal drugs and peptic ulcer diseases. Ann Int Med 114; 307-19, 1991.
6. Schlegel S.I., Paulus H.E.: Non-steroidal and analgesic therapy in the elderly. Clin Rheumat Dis 12; 245-73, 1986.
7. Pincus T., Griffin M.: Gastrointestinal disease associated with non-steroidal anti-inflammatory drugs, new insights from observational studies and functional status questionnaires. Am J Med 91; 209-12, 1991.
8. Hodinka L.: Improving the risk-benefit ratio of NSAID therapy in the elderly. Scand J Rheumatol 9 (suppl.); 3-8, 1991.
9. Weinblatt M.E.: Non steroidal anti-inflammatory drug toxicity:increased risk in the elderly Scan. J. Rheum. 91 (suppl); 9-17, 1991.
10. Tubaro E., Belogi L., Mezzadri C.M., Ruco L., Stoppacciaro A.: Studies on the Gastric Tolerability of the New Non-steroidal Anti-inflammatory Drug Amtolmètine Guacyl. Arzneim Forsch Drug Res 45; 1298-1302, 1995.
11. Graham D.Y., Domschke W., Damman H.G. (editors). In: Prostaglandins and leukotrienes in gastrointestinal diseases. Springer-Verlag,Berlin-Heidelberg. 161-67, 1988.