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Volumn 37, Issue 6, 1997, Pages 1129-1137

Using artificial neural networks to classify the activity of capsaicin and its analogues

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ANALYSIS; COMPUTER SIMULATION; DRUG PRODUCTS; MOLECULAR STRUCTURE; OPTIMIZATION; ORGANIC COMPOUNDS; TOPOLOGY;

EID: 0031260659     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci9700384     Document Type: Article
Times cited : (19)

References (16)
  • 1
    • 0027291395 scopus 로고
    • Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents; Structure - Activity Studies. Part 1. The Aromatic "A-Region"
    • Walpole, C. S. J.; Wrigglesworth, R.; Bevan, S.; Campbell, E. A.; Dray, A.; James, I. F.; Perkins, M. N.; Reid, D. J.; Winter, J. Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents; Structure - Activity Studies. Part 1. The Aromatic "A-Region". J. Med. Chem. 1993, 36, 2362-2372.
    • (1993) J. Med. Chem. , vol.36 , pp. 2362-2372
    • Walpole, C.S.J.1    Wrigglesworth, R.2    Bevan, S.3    Campbell, E.A.4    Dray, A.5    James, I.F.6    Perkins, M.N.7    Reid, D.J.8    Winter, J.9
  • 2
    • 0027296078 scopus 로고
    • Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents; Structure - Activity Studies. Part 2. The Amide-Bond "B-Region
    • Walpole, C. S. J.; Wrigglesworth, R.; Bevan, S.; Campbell, E. A.; Dray, A.; James, I. F.; Perkins, M. N.; Reid, D. J.; Winter, J. Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents; Structure - Activity Studies. Part 2. The Amide-Bond "B-Region J. Med. Chem. 1993, 36, 2373-2380.
    • (1993) J. Med. Chem. , vol.36 , pp. 2373-2380
    • Walpole, C.S.J.1    Wrigglesworth, R.2    Bevan, S.3    Campbell, E.A.4    Dray, A.5    James, I.F.6    Perkins, M.N.7    Reid, D.J.8    Winter, J.9
  • 3
    • 0027270897 scopus 로고
    • Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents; Structure - Activity Studies. Part 3. The Hydrophobic Side-Chain "C-Region"
    • Walpole, C. S. J.; Wrigglesworth, R. ; Bevan, S.; Campbell, E. A.; Dray, A.; James, I. F.; Perkins, M. N.; Reid, D. J.; Winter, J. Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents; Structure - Activity Studies. Part 3. The Hydrophobic Side-Chain "C-Region". J. Med. Chem. 1993, 36, 2381-2389.
    • (1993) J. Med. Chem. , vol.36 , pp. 2381-2389
    • Walpole, C.S.J.1    Wrigglesworth, R.2    Bevan, S.3    Campbell, E.A.4    Dray, A.5    James, I.F.6    Perkins, M.N.7    Reid, D.J.8    Winter, J.9
  • 4
    • 0029319957 scopus 로고
    • Quantitative structure-agonist activity relationship of capsaicin analogues
    • Klopman, G.; Li, J. Quantitative structure-agonist activity relationship of capsaicin analogues. J. Comput. Aided. Mol. Des. 1995, 9, 283-294.
    • (1995) J. Comput. Aided. Mol. Des. , vol.9 , pp. 283-294
    • Klopman, G.1    Li, J.2
  • 5
    • 0029065819 scopus 로고
    • Prediction of Receptor Properties and Binding Affinity of Ligands to Benzodiazepines/GABAA Receptors Using Artificial Neural Networks
    • Maddalena, D. J.; Johnston, J. A. R. Prediction of Receptor Properties and Binding Affinity of Ligands to Benzodiazepines/GABAA Receptors Using Artificial Neural Networks. J. Med. Chem. 1995, 38, 715-724.
    • (1995) J. Med. Chem. , vol.38 , pp. 715-724
    • Maddalena, D.J.1    Johnston, J.A.R.2
  • 6
    • 0029919098 scopus 로고    scopus 로고
    • Applications of Artificial Neural Networks to Quantitative Structure Activity Relationships
    • Maddalena, D. J. Applications of Artificial Neural Networks to Quantitative Structure Activity Relationships. Expert Opin. Ther. Pat. 1996, 6, 239-251.
    • (1996) Expert Opin. Ther. Pat. , vol.6 , pp. 239-251
    • Maddalena, D.J.1
  • 7
    • 0030026012 scopus 로고    scopus 로고
    • Using Artificial Neural Networks to Predict Biological Activity from Simple Molecular Structural Considerations
    • Burden, F. R. Using Artificial Neural Networks to Predict Biological Activity from Simple Molecular Structural Considerations. Quant. Struct. - Act. Relat. 1996, 15, 7-11.
    • (1996) Quant. Struct. - Act. Relat. , vol.15 , pp. 7-11
    • Burden, F.R.1
  • 8
    • 0000526832 scopus 로고
    • Applications of Neural Networks in Chemistry. 1. Prediction of Electrophilic Substitution Reactions
    • Elrod, D. W.; Maggiora, G. M. Applications of Neural Networks in Chemistry. 1. Prediction of Electrophilic Substitution Reactions. J. Chem. Inf. Comput. Sci. 1990, 30, 477-484.
    • (1990) J. Chem. Inf. Comput. Sci. , vol.30 , pp. 477-484
    • Elrod, D.W.1    Maggiora, G.M.2
  • 14
    • 0000241930 scopus 로고
    • Using Molecular Representations in Combination with Neural Networks. A Case Study: Prediction of HPLC Retention Index
    • Meissen, W. J.; Smits, J. R. M.; Daalmans, G. J.; Kateman, G. Using Molecular Representations in Combination with Neural Networks. A Case Study: Prediction of HPLC Retention Index. Comput. Chem. 1994, 157-172.
    • (1994) Comput. Chem. , pp. 157-172
    • Meissen, W.J.1    Smits, J.R.M.2    Daalmans, G.J.3    Kateman, G.4
  • 15
    • 85033179075 scopus 로고    scopus 로고
    • Bioactivnet is a back-propagation ANN generation program available from AiMaze (desm@mail.usyd.edu.au), 14 Birch Place, Kirrawee, NSW 2232, Australia
    • Bioactivnet is a back-propagation ANN generation program available from AiMaze (desm@mail.usyd.edu.au), 14 Birch Place, Kirrawee, NSW 2232, Australia.
  • 16
    • 85033184820 scopus 로고    scopus 로고
    • Use of Artificial Neural Networks as Receptor Pharmacaphores for Flexible Molecules
    • in press
    • Maddalena, D. J.; Johnston, G. A. R. Use of Artificial Neural Networks as Receptor Pharmacaphores for Flexible Molecules. J. Mol. Graph., in press.
    • J. Mol. Graph.
    • Maddalena, D.J.1    Johnston, G.A.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.