Mathematical analysis of an enzymatic reaction in an aqueous/organic two-phase system: Tyrosinase-catalysed hydroxylation of phenol

Journal of Chemical Technology and Biotechnology

Volumn 70, Issue 2, 1997, Pages 163-170

  Chae, Hee Jeong ^a,b   Yoo, Young Je ^a  

^a Seoul National University   (South Korea)

^b R and D Center   (South Korea)

Author keywords

Mass transfer model; Optimization; Organic solvent; Phenol hydroxylation; Two phase reaction; Tyrosinase

Indexed keywords

CATALYSIS; COMPUTER SIMULATION; HYDROXYLATION; INTERFACES (MATERIALS); MASS TRANSFER; MATHEMATICAL MODELS; NUMERICAL ANALYSIS; OPTIMIZATION; ORGANIC COMPOUNDS; ORGANIC SOLVENTS; PHENOLS;

ENZYME INACTIVATION; TWO PHASE SYSTEM; TYROSINASE;

ENZYME KINETICS;

MONOPHENOL MONOOXYGENASE; PHENOL;

ARTICLE; CHEMICAL REACTION KINETICS; ENZYME ACTIVITY; HYDROXYLATION; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; PARTITION COEFFICIENT;

EID: 0031257403     PISSN: 02682575     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4660(199710)70:2<163::AID-JCTB754>3.0.CO;2-9     Document Type: Article

References (22)

1. Brink, L. E. S., Tramper, J., Luyben, K. Ch. A. M. & Van't Riet, K., Biocatalysis in organic media. Enzyme Microb. Technol., 10 (1988) 736-43.
2. Laan, C., Tramper, J. & Lilly, M. D. (eds), Biocatalysis in Organic Media. Elsevier, Amsterdam, 1987.
3. Lilly, M. D., Two-liquid-phase biocatalytic reactions. J. Chem. Tech. Biotechnol., 32 (1982) 162-9.
4. Cassells, J. M. & Halling, P. J., Protease-catalysed peptide synthesis in aqueous-organic two-phase systems: reactant precipitation and interfacial inactivation. Enzyme Microb. Technol., 12 (1990) 755-9.
5. Abramowicz, D. A. & Keese, C. R., Enzymatic transesterifications of carbonates in water-restricted environments. Biotechnol. Bioeng., 33 (1989) 149-56.
6. Woodley, J. M., Brazier, A. J. & Lilly, M. D., Lewis cell studies to determine reactor design data for two-liquid-phase bacterial and enzymic reactions. Biotechnol. Bioeng., 37 (1991) 133-40.
7. Kamat, S., Beckman, E. J. & Russell, A. J., Role of diffusion in nonaqueous enzymology. 1. theory. Enzyme Microb. Technol., 14 (1992) 265-71.
8. Tramper, J., Vermue, M. H., Beeftink, H. H. & von Stocker, U. (eds), Biocatalysis in Non-Conventional Media. Elsevier, Amsterdam, 1992.
9. Antonini, E., Carrea, G. & Cremonesi, P., Enzyme catalysed reactions in water-organic solvent two-phase systems. Enzyme Microb. Technol., 3 (1981) 291-6.
10. Boeren, S. & Laane, C., Steroid conversions by Flavobacterium dehydrogenases in two-liquid-phase systems. Biotechnol. Bioeng., 29 (1987) 305-9.
11. Cantarella, M., Cantarella, L. & Alfani, F., Hydrolytic reactions in two-phase systems. Effect of water-immiscible organic solvents on stability and activity of acid phosphatase, β-glucosidase and β-fructofuranosidase. Enzyme Microb. Technol., 13 (1991) 547-53.
12. Miyake, Y., Ohkubo, M. & Teramoto, M., Lipase-catalysed hydrolysis of 2-naphthyl esters in biphasic system. Biotechnol. Bioeng., 38 (1991) 30-6.
13. Pereira, V., Tigli, H. & Gryte, C. C., Mathematical analysis of two-phase mass transfer in a batch reactor for the chemical transformation of a steroid. Biotechnol. Bioeng., 30 (1987) 505-13.
14. Horowitz, N. H., Feldman, H. M. & Pall, M. L., Depression of tyrosinase synthesis in Neurospora by cycloheximide. J. Biol. Chem., 245 (1970) 2784-8.
15. Ettinger, M. B., Ruchhoft, C. C. & Lishka, R. J., Sensitive 4-aminoantipyrine method for phenolic compounds. Anal. Chem., 23 (1951) 1783-7.
16. Arnow, L. E., Colorimetric determination of the components of 3,4-dihydroxyphenylalanine-tyrosine mixtures. J. Biol. Chem., 118 (1937) 531-7.
17. Nelson, J. M. & Dawson, C. R., Tyrosinase. In Advances in Enzymology, eds F. F. Nord & C. H. Werkman. Interscience, New York, 1944, pp. 99-152.
18. Asimov, I. & Dawson, C. R., On the reaction inactivation of tyrosinase during the aerobic oxidation of catechol. J. Am. Chem. Soc., 72 (1950) 820-8.
19. Ingraham, L. L., Reaction-inactivation of polyphenol oxidase: catechol and oxygen dependence. J. Am. Chem. Soc., 77 (1955) 2875-6.
20. Cánovas, F. G., Tudela, J., Madrid, C. M., Varón, R., Carmona, F. G. & Lozano, J. A., Kinetic study on the suicide inactivation of tyrosinase induced by catechol. Biochim. Biophys. Acta, 912 (1987) 417-23.
21. Kazandjian, R. Z. & Klibanov, A. M., Regioselective oxidation of phenols catalysed by polyphenol oxidase in chloroform. J. Am. Chem. Soc., 107 (1985) 5448-50.
22. Press, W. H., Flannery, B. P., Teukolsky, S. A. & Vetterling, W. T. (eds), Numerical Recipes: The Art of Scientific Computing. Cambridge Univ. Press, New York, 1986.