Oral coenzyme Q10 administration prevents the development of ischemic brain lesions in a rabbit model of symptomatic vasospasm

Acta Neuropathologica

Volumn 94, Issue 4, 1997, Pages 363-368

  Grieb, Paweł ^a   Ryba, Mirosław S ^a   Sawicki, Jan ^a   Chrapusta, Stanisław J ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Antioxidants; Free radicals; Low density lipoproteins; Subarachnoid hemorrhage

Indexed keywords

LIPOPROTEIN; UBIDECARENONE; ANTIOXIDANT; DRUG DERIVATIVE; LOW DENSITY LIPOPROTEIN; UBIQUINONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN STEM; BRAIN VASOSPASM; CONTROLLED STUDY; FEMALE; LIPOPROTEIN BLOOD LEVEL; MALE; MONONUCLEAR CELL; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RABBIT; SUBARACHNOID SPACE; ANIMAL; BLOOD; BRAIN; DRUG EFFECT; LIPID PEROXIDATION; PATHOLOGY; SUBARACHNOID HEMORRHAGE; TRANSIENT ISCHEMIC ATTACK;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; BRAIN; FEMALE; ISCHEMIC ATTACK, TRANSIENT; LIPID PEROXIDATION; LIPOPROTEINS, LDL; MALE; RABBITS; SUBARACHNOID HEMORRHAGE; UBIQUINONE;

EID: 0031255803     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050720     Document Type: Article

References (39)

1. Asano T (1987) Relevance of the metabolism of membrane lipids to cerebral vasospasm and ischemic brain damage. In: Sano K, Asano T, Tamura A (eds) Acute aneurysm surgery. Springer, Wien New York, pp 53-125
2. Asano T, Takakura K, Sano K, Kikuchi H, Nagai H, Saito I, Tamura A, Ochiai C, Sasaki T (1996) Effects of a hydroxyl radical scavenger on delayed ischemic neurological deficits following aneurysmal subarachnoid hemorrhage: results of a multicenter, placebo-controlled double-blind trial. J Neurosurg 84: 792-803
3. Brightman MW (1989) The anatomic basis of the blood-brain barrier. In: Neuwelt EA (ed) Implications of the blood-brain barrier and its manipulation, vol I; Basic science aspects. Plenum Medical Book, New York, pp 53-83
4. Charcot JM, Bouchard CH (1988) Nouvelles recherches sur la pathogenic de l'hemorrhagie cerebrale. Arch Physiol Paris 1: 110
5. Chungcharoen D, De Burgh Daly M, Neil E, Schweitzer A (1952) The effect of carotid occlusion upon the intrasinusal pressure with special reference to vascular communications between the carotid and vertebral circulations in the dog, cat and rabbit. J Physiol (Lond) 117: 56-76
6. Chyatte D, Sundt TM Jr (1984) Response of chronic experimental cerebral vasospasm to methylprednisolone and dexamethasone. J Neurosurg 60: 932-936
7. Cole FM, Yates PO (1967) Intracerebral microaneurysms and small cerebrovascular lesions. Brain 90: 759-768
8. Cole FM, Yates PO (1967) The occurrence and significance of intracerebral microaneurysms. J Pathol Bacteriol 93: 393-411
9. Duff TA, Louie J, Feilbach JA, Scott G (1988) Erythrocytes are essential for development of cerebral vasculopathy resulting from subarachnoid hemorrhage in cats. Stroke 19: 68-72
10. Endo S, Branson P, Alksne JF (1988) Experimental model of symptomatic vasospasm in rabbits. Stroke 19: 1420-1425
11. Foley PL, Kassell NF, Hudson SB, Lee KS (1993) Hemoglobin penetration in the wall of the basilar artery after subarachnoid hemorrhage. In: Findlay JM (ed) Cerebral vasospasm. Proceedings of the Vth international conference on cerebral vasospasm, Edmonton and Jasper, Alberta, Canada, 17-21 May 1993. Elsevier, Amsterdam, pp 155-158
12. Halliwell B (1994) Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? Lancet 344: 721-724
13. Handa Y, Hayashi M, Takeuchi H, Kabayashi H, Kawano H, Kabuto M (1991) Effect of cyclosporine on the development of cerebral vasospasm in a primate model. Neurosurgery 28: 542-549
14. Heros RC, Zervas NT, Varsos V (1983) Cerebral vasospasm after subarachnoid hemorrhage: an update. Ann Neurol 14: 599-608
15. Ishii R (1979) Regional blood flow in patients with ruptured intracranial aneurysms. J Neurosurg 50: 587-594
16. Johshita H, Kassel NF, Sasaki T (1990) Blood-brain barrier disturbance following subarachnoid hemorrhage in rabbits. Stroke 21: 1051-1058
17. Kassell NF, Sasaki T, Colohan ART, Nazar G (1985) Cerebral vasospasm following subarachnoid hemorrhage. Stroke 16: 562-572
18. Macdonald RL, Weir BKA (1991) A review of hemoglobin and the pathogenesis of cerebral vasospasm. Stroke 22: 971-982
19. Mayberg MR, Okada T, Bark DH (1990) The role of hemoglobin in arterial narrowing after subarachnoid hemorrhage. J Neurosurg 72: 634-640
20. Misra HP, Fridovich I (1972) The generation of superoxide radical during the autooxidation of hemoglobin. J Biol Chem 21: 6960-6962
21. 10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta 1126: 247-254
22. Nakagomi T, Yamakawa K, Tsubaki S, Sasaki T, Saito I, Takakura K (1990) Effect of a new free radical scavenger, MCI-186, on experimental cerebral vasospasm. In: Sano K, Takakura K, Kassell NF, Sasaki T (eds) Cerebral vasospasm. University of Tokyo Press, Tokyo, pp 141-142
23. Ohue S, Sakaki S, Nakamura H, Kohno K, Matsuoka K (1990) Free radical reaction and biological defense mechanism in the pathogenesis of prolonged vasospasm. In: Sano K, Takakura K, Kassell NF, Sasaki T (eds) Cerebral vasospasm. University of Tokyo Press, Tokyo, pp 137-138
24. Peterson JW, Nishizawa S, Hackett JD, Bun T, Teramura A, Zervas NT (1990) Cyclosporine A reduces cerebral vasospasm after subarachnoid hemorrhage in dogs. Stroke 21: 133-137
25. Russell RWR (1963) Observations of intracranial aneurisms. Brain 86: 425-441
26. Ryba M, Pastuszko M, Iwańska K, Bidziński J, Dziewiȩcki C (1992) Cyclosporine A prevents neurological deterioration of patients wit SAH - a preliminary report. Acta Neurochir (Wien) 112: 25-27
27. Ryba M, Jarza̧bek-Chorzelska M, Chorzelski T, Pastuszko M (1992) Is vascular angiopathy following intracranial aneurysm rupture immunologically mediated? Acta Neurochir (Wien) 117: 34-36
28. Ryba M, Grieb P, Walski M, Sawicki J, Pastuszko M (1993) 2-Chloro-2′-deoxyadenosine prevents angiopathic changes in cerebral arteries in experimental SAH in rabbits. Acta Neurochir (Wien) 122: 118-121
29. Ryba M, Grieb P, Pastuszko M, Wȩgier-Filipiuk B, Mrowiec E, Andrychowski J, Konopka L (1993) Impaired in vitro proliferative response of suppressor lymphocytes in patients with subarachnoid haemorrhage from ruptured intracranial aneurysm. Acta Neurochir (Wien) 122: 240-243
30. Ryba M, Grieb P, Pastuszko M, Bidziński J, Andrychowski J, Dziewiȩcki C, Bojarski P, Królicki L (1993) Succesful prevention of neurological deficits in SAH patients with 2-chloro-deoxyadenosine. Acta Neurochir (Wien) 124: 61-65
31. Sano K (1994) Acute ischaemic and delayed ischaemic neurological deficits as the causes of bad grading in aneurysmal subarachnoid hemorrhage. Neurol Res 16: 35-39
32. Sasaki T, Wakai S, Asano T, Watanabe T, Kirino T, Sano K (1981) The effect of a lipid hydroperoxide of arachidonic acid on the canine basilar artery. J Neurosurg 54: 357-365
33. Sasaki T, Kassell N, Yamashita M, Fujiwara S, Zuccarello M (1985) Barrier disruption in the major cerebral arteries following experimental subarachnoid hemorrhage. J Neurosurg 63: 443-440
34. Shepherd J, Bicker S, Lorimer AR, Packard CJ (1979) Receptor-mediated low density lipoprotein catabolism in man. J Lipid Res 20: 999-1006
35. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 320: 915-924
36. Wahlgren NG, Bergstrom K (1983) Determination of haem derivatives in the cerebrospinal fluid: a semi-quantitative method. J Neurol Neurosurg Psychiatry 46: 653-658
37. Watanabe T, Asano T, Shimizu T, Seyama Y, Takakura K (1988) Participation of lipoxygenase products from arachidonic acid in the pathogenesis of cerebral vasospasm. J Neurochem 50: 1145-1150
38. Watanabe T, Hori T, Asano T, Saito I, Takakura K, Sano K (1990) Effects of ebselen (PZ-51) on experimental and clinical cerebral vasospasm. In: Sano K, Takakura K, Kassell NF, Sasaki T (eds) Cerebral vasospasm. University of Tokyo Press, Tokyo, pp 139-140
39. Weir BKA (1983) The relationship between arterial spasm and neurological deficits. In: Battye R (ed) Calcium antagonists. Possible therapeutic role in neurosurgery. Dorado Beach, Puerto Rico