The role of the epithelium in mucosal immunity

Research in Immunology

Volumn 148, Issue 8-9, 1997, Pages 498-504

  Mayer, L ^a  

^a MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN; CD1 ANTIGEN; CD8 ANTIGEN; CYTOKINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; CELL INTERACTION; CYTOKINE RELEASE; IMMUNOGENICITY; IMMUNOREGULATION; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; LYMPHOCYTE SUBPOPULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MUCOSAL IMMUNITY; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE ACTIVATION;

EID: 0031254998     PISSN: 09232494     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2494(98)80143-0     Document Type: Article

References (60)

1. [1] Wiman, K., Curman, B., Forsum, U., Klareskvg, L., Malmas-Tjernlund, U., Rask, L., Tragardh, L. & Peterson, P.A. (1978), Occurrence of Ia antigens on tissues of non-lymphoid origin. Nature, 276, 711-713.
2. [2] Kalb, T.H., Chuang, M.T., Marom, Z. & Mayer, L. (1991), Evidence for accessory cell function by class II MHC antigen expressing airway epithelial cells. Am. J. Resp. Cell Mol. Biol., 4, 320-329.
3. [3] Mayrhofer, G. & Schon-Hegrad, M.A. (1983), Ia antigens in rat kidney with special reference to their expression in tubular epithelium. J. Exp. Med., 157, 2097-2109.
4. [4] Bottazzo, G.F., Pujo-Burrell, R., Hanafusa, T. & Feldmann, M. (1983), Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity. Lancet, ii, 1115-1117.
5. [5] Sanderson, I.R., Oullette, A.J., Carter, E.A., Walker, W.A. & Harmatz, P.R. (1993), Differential regulation of B7 mRNA in enterocytes and lymphoid cells. Immunology, 79, 434-438.
6. [6] Targan, S.R., Kagnoff, M.F., Brogan, M.D. & Shanahan, F. (1987), Immunologic mechanisms in intestinal diseases. Ann. Int. Med., 106, 853-870.
7. [7] Mayer, L., So, L.P., Yio, X.Y. & Small, G. (1996), Antigen trafficking in the Intestine. Ann. N.Y. Acad. Sci., 778, 28-35.
8. [8] Webb, K.E. (1986), Amino acid and peptide absorption from the gastrointestinal tract. Fed. Proc., 45, 2268-2271.
9. [9] Gonella, P.A. & Neutra, M.R. (1984), Membrane-bound and fluid-phase macromolecules enter separate prelysosomal compartments in absorptive cells of suckling rat ileum. J. Cell Biol, 99, 907-917.
10. [10] Gonella, P.A. & Wilmore, D.W. (1993), Co-localization of class II antigen and exogenous antigen in the rat enterocyte. J. Cell Sci., 106, 937-940.
11. [12] Heyman, M., Lain-Denoyelle, A.M., Nath, S.K. & Desjeux, J.F. (1990), Quantification of protein transcytosis in the human colon carcinoma cell line Caco-2. J. Cell. Physiol., 143, 391-395.
12. [12] Hughson, E.J. & Hopkins, C.R. (1990), Endocytic pathway in polarized Caco-2 cells: identification of an endosomal compartment accessible form both apical and basolateral surfaces. J. Cell Biol., 110, 337-348.
13. [12] Hughson, E.J., Cutler, D.F. & Hopkins, C.R. (1989), Basolateral secretion of kappa light chain in the polarised epithelial cell line, Caco-2. J. Cell Sci., 94, 327-332.
14. [13] Brandeis, J.M., Sayegh, M.H., Gallon, L. et al. (1994), Rat intestinal epithelial cells present major histocompatibility complex allopeptides to primed T cells. Gastroenterology, 107, 1537-1542.
15. [15] Berin, M.C., Kiliaan, A.J., Yang, P.C., Groot, J.A., Taminiau, J.A.J.M. & Perdue, M.H. (1997), Rapid transepithelial antogen transport in rat jejunum: impact of sensitization and the hypersensitivity reaction. Gastroenterology, 113, 856-864.
16. [16] Bland, P.W. & Whiting, C.V. (1989), Antigen processing by isolated rat intestinal villus enterocytes. Immunology, 68(4), 497-502.
17. [17] Panja, A., Barrone, A. & Mayer, L. (1994), Stimulation of lamina propria lymphocytes by intestinal epithelial cells: evidence for recognition of nonclassical classI/II molecules. J. Exp. Med., 179, 943-950.
18. [18] Bland, P.W. & Warren, L.G. (1986), Antigen presentation by epithelial cells of the rat small intestine. -I. Kinetics, antigen specificity and blocking by anti-Ia antisera. Immunology, 58, 1-7.
19. [19] Chapman, H.A., Jr, Munger, J.S. & Shi, G.P. (1994), The role of thiol proteases in tissue injury and remodeling. Am. J. Respir. Crit. Care Med., 150, S155-S159.
20. [20] Finzi, G., Cornaggia, M., Capeella, C., Fiocca, R., Bosi, F., Solcia, E. & Samloff, I.M. (1993). Cathepsin E in follicle-associated epithelium of intestine and tonsils: localization to M cells and possible role in antigen processing. Histochemistry, 99, 201-211.
21. [21] Hershberg, R.M., Framson, P.E., Cho, D.H., Lee, L.Y., Kovats, S., Baltz, J., Blum, J.B. & Nepom, G.T. (1997), Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing. J. Clin. Invest., 100, 204-215.
22. [22] Sanderson, I.R., Oullette, A.J., Carter, E.A. & Harmatz, P.R. (1993), Ontogeny of Ia messenger RNA in the mouse small intestinal epithelium is modulated by age of weaning and diet. Gastroenterology, 105, 974-980.
23. [23] Mayer, L. & Shlien, R. (1987), Evidence for function of a Ia molecule on gut epithelial cells in man. J. Exp. Med., 166, 1471.
24. [24] Bland, P.W. & Warren, L.G. (1986), Antigen presentation by epithelial cells of the rat small intestine. -II. Selective induction of suppressor T cells. Immunology, 58, 9-24.
25. [25] Panja, A., Blumberg, R.S., Balk, S.P. & Mayer, L. (1993), CD1d is involved in T cell: epithelial cell interactions. J. Exp. Med., 178, 1115-1120.
26. [26] Balk, S.P., Ebert, E.C., Blumenthal, R.L., McDermott, F.V. et al. (1991), Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes. Science, 253, 1411.
27. [27] Hershberg, R., Eghtesady, P., Sydora, B., Brorson, K. et al. (1990), Expression of the thymus leukemia antigen in mouse intestinal epithelium. Proc. Natl. Acad. Sci. USA, 87(24), 9727-9731.
28. [28] Castano, A.R., Tangri, S., Miller, J.E.W., Holcombe, H.R., Jackson, M.R., Huse, W.D., Kronenberg, M. & Peterson, P.A. (1995), Peptide binding and presentation by mouse CD1, Science, 269, 223-226.
29. [29] Beckman, E.M., Porcelli, S.A., Morita, C.T., Behar, S.M., Furlong, S.T. & Brenner, M.B. (1994), Recognition of a lipid antigen by CD1, restricted alpha beta+ T cells. Nature, 372, 691-694.
30. [30] Jullien, D., Stenger, S., Ernst, W.A. & Modlin, R.L. (1997), CD1 presentation of microbial nonpeptide antigens to T cells. J. Clin. Invest., 99(9), 2071-2074.
31. [31] Doyle, C. & Strominger, J.L. (1987), Interaction between CD4 and Class II MHC molecules mediates cell adhesion. Nature, 330, 256-259.
32. [32] Gallagher, P.F., de St. Groth, B.F. & Miller, J.F. (1989), CD4 and CD8 molecules can physically associate with the same T cell receptor. Proc. Natl. Acad. Sci. USA, 86, 10044-10048.
33. [33] Li, Y., Yio, X.Y. & Mayer, L. (1995), Human intestinal epithelial cell induced CD8+ T cell activation is mediated through CD8 and the activation of CD8-associated p561ck. J. Exp. Med., 182, 1079-1088.
34. [34] Yio, X. Y. & Mayer, L. (1997), Characterization of a 180 kDa intestinal epithelial cell membrane glycoprotein, gp180: a candidate molecule mediating T cell: epithelial cell interactions. J. Biol. Chem., 272, 12786-12792.
35. [35] Campbell, N., Yio, X.Y., Blumberg, R. & Mayer, L. (1996), Non-classical class I molecule CD1d, associates with gp180, a CD8 ligand expressed by intestinal epithelial cells. Gastroenterology, 110, A876.
36. [36] Kaiserlian, D., Vidal, K. & Revillard, J.P. (1989), Murine enterocytes can present soluble antigen to specific class II, restricted CD4+ T cells. Eur. J. Immunol., 12(8), 1513-1516.
37. [37] Mayer, L., Siden, E., Becker, S. & Eisenhardt, D. (1990), Antigen handling in the intestine mediated by normal enterocytes, in "Adv. Mucosal Immunol." (MacDonald, Challacombe, Bland, Stokes, Healthy, Mowat) (pp. 23-2886). Kluwer Acad. Pub. Dordrecht, Netherlands.
38. [38] Mayer, L. & Eisenhardt, D. (1990), Lack of induction of suppressor T cells by intestinal epithelial cells from patients with inflammatory bowel disease. J. Clin. Invest., 86, 1255-1260.
39. [39] Nakazawa, A., Kanai, T., Hayashi, T., Naganuma, N., Iwao, Y., Ishii, H., Azuma, M., Watanabe, W. & Hibi, T. (1997), The expression and function of costimulatory molecules CD86 in the colonic epithelial cells. Gastroenterology, 112, A1049 (abstract).
40. [40] Ernst, P.B., Dean Befus, A. & Bienenstock, J. (1985), Leukocytes in the intestinal epithelium: an unusual immunological compartment. Immunol. Today, 6, 50-55.
41. [41] James, S.P., Zeitz, M., Kanof, M. & Kwan, W.C. (1988), Intestinal lymphocyte populations and mechanisms of cell-mediated immunity. Immunol. Allergy Clin. North Am., 8, 369-391.
42. [42] Huang, G.T., Eckmann, L., Savidge, T.C. & Kagnoff, M.F. (1996), Infection of human intestinal epithelial cells with invasive bacteria upregulates apical intercellular adhesion molecule-1 (ICAM-1) expression and neutrophil adhesion. J. Clin. Invest., 98(2), 572-583.
43. [43] Parkos, C.A., Colgan, S.P., Diamond, M.S., Nusrat, A., Liang, T.W., Springer, T.A. & Madara, J.L. (1996), Expression and polarization of intercellular adhesion molecule-1 on human intestinal epithelia: consequences for CD11b/CD18-mediated interactions with neutrophils. Mol. Med., 2(4), 489-505.
44. [44] Mayer, L., Panja, A., Li, Y., Siden, E., Pizzimenti, A., Gerardi, F. & Chandswang, N. (1992), Unique features of antigen presentation in the intestine. Ann. N.Y. Acad. Sci. 664, 39-47.
45. [45] Eckmann, L., Kagnoff, M.F. & Fierer, J. (1993), Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect. Immun., 61, 4569-4574.
46. [46] Eckman, L., Jung, H.C., Schurer-Maly, C., Panja, A., Morzycka-Wroblewska, E. & Kagnoff, M. (1993), Differential cytokine expression by human intestinal epithelial cells: regulated expression of interleukin-8. Gastroenterology, 105, 1689-1697.
47. [47] McGee, D.W., Beagley, K., Aicher, W.K. & McGhee, J.R. (1995), The regulation of IL-6 secretion from IEC-6 intestinal epithelial cells by cytokines and mucosally important antigens. Adv. Exp. med. Biol., 371A, 229-232.
48. [48] Reinecker, H.C., Loh, E.Y., Ringler, D.J., Mehta, A., Rombeau, J.L. & MacDermott, R.P. (1995), Monocyte-chemoattractant protein-1 gene expression in intestinal epithelial cells and inflammatory bowel disease. Gastroenterology, 108, 40-50.
49. [49] Panja, A., Siden, E. & Mayer, L. (1995), Synthesis and regulation of accessory/proinflammatory cytokines by intestinal epithelial cells. Clin. Exp. Immunol, 100, 298-305.
50. [50] Casini-Raggi, V., Kam, L., Chong, Y.J., Fiocchi, C., Pizarro, T.T. & Cominelli, F. (1995). Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. J. Immunol., 154(5), 2434-2440.
51. [51] McGee, D.W., Beagley, K.W., Aicher, W.K. et al. (1993), Transforming growth factor-b and IL-1b act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6. J. Immunol., 151, 970-978.
52. [52] Panja, A., Krishen, P. & Mayer, L. (1996), Expression of IL10 receptor on human epithelial cells and its functional consequences. Gastroenterology, 110, A986 (abstract).
53. [53] Suemoris, S., Ciacci, C. & Podolsky, D.K. (1991), Regulation of transforming growth factor expression in rat intestinal epithelial cell line. J. Clin. Invest., 87, 2216-2221.
54. [54] Giannasca, P.J., Giannasca, K.T., Falk, P., Gordon, J.I. & Neutra, M.R. (1994), Regional differences in glycoconjugates of intestinal M cells in mice: potential targets for mucosal vaccines. Am. J. Physiol., 267, 1108-1121.
55. [55] Sicinki, P.J., Rowinski, J.B., Warchol, A. et al. (1990), Poliovirus type I enters the human host through intestinal M cells. Gastroenterology, 98, 56-58.
56. [56] Bass, D.M., Trier, J.S., Dambrauskas, R. & Wolf, J.L. (1988), Reovirus type I infection of small intestinal epithelium in suckling mice and its effect on M cells. Lab. Invest., 58, 226-235.
57. [57] Frey, A., Giannasca, K.T., Weltzin, R., Giannasca, P.J., Reggio, H., Lencer, W.I. & Neutra, M.R. (1996), Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting. J. Exp. Med., 184(3), 1045-1059.
58. [58] Coffman, R.L., Lebman, D.A. & Shrader, B. (1989), Transforming growth factor-β specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes. J. Exp. Med., 170, 1039-1044.
59. [59] Richman, L.K., Graeff, A.S., Yarchoan, R. & Strober, W. (1981), Simultaneous induction of antigen-specific IgA helper T cells and IgG suppressor T cells in the murine Peyer's patch after protein feeding. J. Immunol., 126, 6, 2079-2083.
60. [60] Santos, L.M., Al-Sabbagh, A., Londono, A. & Weiner, H.L. (1994), Oral tolerance to myelin basic protein induces regulatory TGF-beta-secreting T cells in Peyer's patches of SJL mice. Cell Immunol., 157, 439-447.