-
1
-
-
0024603946
-
The double prodrug concept and its applications
-
Bundgaard H., "The double prodrug concept and its applications." Adv. Drug. Deliv. Rev. 3:39-65, 1989.
-
(1989)
Adv. Drug. Deliv. Rev.
, vol.3
, pp. 39-65
-
-
Bundgaard, H.1
-
2
-
-
0016622773
-
Structure and properties of pharmacologically active polymers
-
Ringsdorf H., "Structure and properties of pharmacologically active polymers." J. Polymer Sci. Symposia 51:135-, 1975.
-
(1975)
J. Polymer Sci. Symposia
, vol.51
, pp. 135
-
-
Ringsdorf, H.1
-
3
-
-
0024410772
-
Soluble macromolecular carriers for the delivery of antitumor drugs
-
Sesaki H., Takakura Y. and Hashida M., "Soluble macromolecular carriers for the delivery of antitumor drugs." Adv. Drug Deliv. Rev. 3:247-, 1989.
-
(1989)
Adv. Drug Deliv. Rev.
, vol.3
, pp. 247
-
-
Sesaki, H.1
Takakura, Y.2
Hashida, M.3
-
4
-
-
0003013730
-
Antimetabolites
-
(Eds., Goodman L.S., Sarkar F.H., Crissman J.D. and Fridman R.) McMillan New York
-
Calabresi P. and Parks Jr. R.E., "Antimetabolites." In: Pharmacological Basis of Therapeutics (Eds., Goodman L.S., Sarkar F.H., Crissman J.D. and Fridman R.) pp. 1268-1276, McMillan New York, 1985.
-
(1985)
Pharmacological Basis of Therapeutics
, pp. 1268-1276
-
-
Calabresi, P.1
Parks Jr., R.E.2
-
5
-
-
11944275900
-
New aspects of polymer drugs
-
Akashi M. and Takemoto K., "New aspects of polymer drugs." Adv. Polymer Sci. 97:108-146, 1990.
-
(1990)
Adv. Polymer Sci.
, vol.97
, pp. 108-146
-
-
Akashi, M.1
Takemoto, K.2
-
6
-
-
0025327413
-
Synthesis and antitumor activity of conjugates of poly(α-malic acid) and 5-fluorouracil bound via ester, amide or carbamoyl bonds
-
Ouchi T., Fujino A., Tanaka K. and Banba Y., "Synthesis and antitumor activity of conjugates of poly(α-malic acid) and 5-fluorouracil bound via ester, amide or carbamoyl bonds." J. Controlled Release 12:143-153, 1990.
-
(1990)
J. Controlled Release
, vol.12
, pp. 143-153
-
-
Ouchi, T.1
Fujino, A.2
Tanaka, K.3
Banba, Y.4
-
7
-
-
0026466814
-
Synthesis and antitumor activity of poly(ethylene glycol)s linked to 5-fluorouracil via urethane or urea bonds
-
Ouchi T., Hagihara Y., Takashi K., Takano Y. and Igarashi I., "Synthesis and antitumor activity of poly(ethylene glycol)s linked to 5-fluorouracil via urethane or urea bonds," Drug Design Discovery 9:93-105, 1992.
-
(1992)
Drug Design Discovery
, vol.9
, pp. 93-105
-
-
Ouchi, T.1
Hagihara, Y.2
Takashi, K.3
Takano, Y.4
Igarashi, I.5
-
8
-
-
0025086630
-
Synthesis and antitumor activity of conjugates of 5-fluorouracil and chito-oligosaccharides involving a hexamethylene spacer group and carbamoyl bonds
-
Ouchi T., Banba T., Matsumoto T., Suzuki S. and Suzuki M., "Synthesis and antitumor activity of conjugates of 5-fluorouracil and chito-oligosaccharides involving a hexamethylene spacer group and carbamoyl bonds." Drug Design Delivery 6:281-287, 1990.
-
(1990)
Drug Design Delivery
, vol.6
, pp. 281-287
-
-
Ouchi, T.1
Banba, T.2
Matsumoto, T.3
Suzuki, S.4
Suzuki, M.5
-
9
-
-
0029089856
-
Macromolecular prodrugs of 5-fluorouracil. 1. Synthesis and hydrolytic stability
-
Nichifor M., Coessens V. and Schacht E. H., "Macromolecular prodrugs of 5-fluorouracil. 1. Synthesis and hydrolytic stability." J. Bioact. Comp. Polymers 10:199-222, 1995.
-
(1995)
J. Bioact. Comp. Polymers
, vol.10
, pp. 199-222
-
-
Nichifor, M.1
Coessens, V.2
Schacht, E.H.3
-
10
-
-
0029877192
-
Macromolecular prodrugs of 5-fluorouracil. 2. Enzymatic degradation
-
Nichifor M., Seymour L. W. and Schacht E. H., "Macromolecular prodrugs of 5-fluorouracil. 2. Enzymatic degradation." J. Controlled Release 39:79-92, 1996.
-
(1996)
J. Controlled Release
, vol.39
, pp. 79-92
-
-
Nichifor, M.1
Seymour, L.W.2
Schacht, E.H.3
-
11
-
-
0028997949
-
In vitro cytotoxicity of macromolecules in different cell culture systems
-
Choksakulnimitr S., Masuda S., Tokuda H., Takakura Y. and Hashida M., "In vitro cytotoxicity of macromolecules in different cell culture systems." J. Controlled Release 34:233-241, 1995.
-
(1995)
J. Controlled Release
, vol.34
, pp. 233-241
-
-
Choksakulnimitr, S.1
Masuda, S.2
Tokuda, H.3
Takakura, Y.4
Hashida, M.5
-
12
-
-
0027253357
-
The conjugation of proteins with polyethylene glycol and other polymers
-
Katre N. V., "The conjugation of proteins with polyethylene glycol and other polymers." Adv. Drug Deliv. Rev. 10:91-114, 1993.
-
(1993)
Adv. Drug Deliv. Rev.
, vol.10
, pp. 91-114
-
-
Katre, N.V.1
-
13
-
-
0029216790
-
Effects of concentration, molecular weight, and exposure time of poly(ethylene glycol) on cell fusion
-
Nakajima N. and Ikada Y., "Effects of concentration, molecular weight, and exposure time of poly(ethylene glycol) on cell fusion." Polymer J. 27:211-219, 1995.
-
(1995)
Polymer J.
, vol.27
, pp. 211-219
-
-
Nakajima, N.1
Ikada, Y.2
-
14
-
-
0028145291
-
Cathepsin B and other proteases in human colorectal carcinoma
-
Milburn Jessup J., "Cathepsin B and other proteases in human colorectal carcinoma." Am. J. Patol 145:253-262, 1994.
-
(1994)
Am. J. Patol
, vol.145
, pp. 253-262
-
-
Milburn Jessup, J.1
-
15
-
-
0028145293
-
Cathepsin B expression in colorectal carcinomas correlates with tumor progression and shortened patient survival
-
Campo E., Munoz J., Miquel R., Palacin A., Cardesa A., Sloane B.F. and Emmert-Buck M.R., "Cathepsin B expression in colorectal carcinomas correlates with tumor progression and shortened patient survival." Am. J. Patol 145:301-309, 1994.
-
(1994)
Am. J. Patol
, vol.145
, pp. 301-309
-
-
Campo, E.1
Munoz, J.2
Miquel, R.3
Palacin, A.4
Cardesa, A.5
Sloane, B.F.6
Buck, M.R.7
-
16
-
-
0027235785
-
Preparation and properties of monomethoxy poly(ethylene glycol) doxorubicin conjugates linked by an amino acid or a peptide as spacer
-
Caliceti P., Monfardini C., Sartore L., Schiavon O., Baccichetti E, Carlassare F. and Veronese F.M., "Preparation and properties of monomethoxy poly(ethylene glycol) doxorubicin conjugates linked by an amino acid or a peptide as spacer." Il Farmaco 48:919-932, 1993.
-
(1993)
Il Farmaco
, vol.48
, pp. 919-932
-
-
Caliceti, P.1
Monfardini, C.2
Sartore, L.3
Schiavon, O.4
Baccichetti, E.5
Carlassare, F.6
Veronese, F.M.7
-
17
-
-
0017336288
-
High molecular weight derivatives of methotrexate as chemotherapeutic agents
-
Chu B.C.F. and Whiteley J.M., "High molecular weight derivatives of methotrexate as chemotherapeutic agents." Mol. Pharmacol 13:80-88, 1977.
-
(1977)
Mol. Pharmacol
, vol.13
, pp. 80-88
-
-
Chu, B.C.F.1
Whiteley, J.M.2
-
18
-
-
0028281777
-
Covalent coupling of methotrexate to dextran enhances the penetration of cytotoxicity into a tissue-like matrix
-
Dang W., Colvin O.M., Brem H. and Saltzman W.M., "Covalent coupling of methotrexate to dextran enhances the penetration of cytotoxicity into a tissue-like matrix." Cancer Res. 54:1729-1735, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1729-1735
-
-
Dang, W.1
Colvin, O.M.2
Brem, H.3
Saltzman, W.M.4
-
19
-
-
0023450012
-
Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal and intravenous administration to rats
-
Seynour L.W., Duncan R., Strohalm J. and Kopecek J., "Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal and intravenous administration to rats." J. Biomed Mater. Res. 21:1341-1358, 1987.
-
(1987)
J. Biomed Mater. Res.
, vol.21
, pp. 1341-1358
-
-
Seynour, L.W.1
Duncan, R.2
Strohalm, J.3
Kopecek, J.4
-
20
-
-
0026694788
-
Passive tumor targeting of soluble macromolecules and drug conjugates
-
Seymour L.W., "Passive tumor targeting of soluble macromolecules and drug conjugates." Crit. Rev. Therapeut. Drug Carrier Syst. 9:135-187, 1992.
-
(1992)
Crit. Rev. Therapeut. Drug Carrier Syst.
, vol.9
, pp. 135-187
-
-
Seymour, L.W.1
-
21
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer therapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS
-
Matsumura Y. and Maeda H. "A new concept for macromolecular therapeutics in cancer therapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS." Cancer Res. 46:6387-6393, 1986.
-
(1986)
Cancer Res.
, vol.46
, pp. 6387-6393
-
-
Matsumura, Y.1
Maeda, H.2
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