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Volumn 159, Issue 7, 1997, Pages 3354-3363

Domain-Switched Mouse IgM/IgG2b Hybrids Indicate Individual Roles for Cμ2, Cμ3, and Cμ4 Domains in the Regulation of the Interaction of IgM with Complement C1q

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1Q; HYBRID PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

EID: 0031252319     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (22)

References (49)
  • 1
    • 0016637561 scopus 로고
    • Characterization of a plasmin-digesl fragment of rabbit immunoglobulin gamma that binds antigen and complement
    • Colomb, M., and R. R. Porter. 1975. Characterization of a plasmin-digesl fragment of rabbit immunoglobulin gamma that binds antigen and complement. Biochem. J. 145:177.
    • (1975) Biochem. J. , vol.145 , pp. 177
    • Colomb, M.1    Porter, R.R.2
  • 2
    • 0017253131 scopus 로고
    • Structure and function of immunoglobulin domains. III. Isolation and characterization of a fragment corresponding to the Cγ2 homology region of human immunoglobulin G
    • Ellerson, J. R., D. Yasmeen, R. H. Painter, and K. J. Dorrington. 1976. Structure and function of immunoglobulin domains. III. Isolation and characterization of a fragment corresponding to the Cγ2 homology region of human immunoglobulin G. J. Immunol. 116:510.
    • (1976) J. Immunol. , vol.116 , pp. 510
    • Ellerson, J.R.1    Yasmeen, D.2    Painter, R.H.3    Dorrington, K.J.4
  • 3
    • 0017250165 scopus 로고
    • The structure and function of immunoglobulin domains. IV. The distribution of some effector functions among the Cγ2 and Cγ3 homology regions of human immunoglobulin G
    • Yasmeen, D., J. R. Ellerson, K. J. Dorrington, and R. H. Painter. 1976. The structure and function of immunoglobulin domains. IV. The distribution of some effector functions among the Cγ2 and Cγ3 homology regions of human immunoglobulin G. J. Immunol. 116:518.
    • (1976) J. Immunol. , vol.116 , pp. 518
    • Yasmeen, D.1    Ellerson, J.R.2    Dorrington, K.J.3    Painter, R.H.4
  • 4
    • 0023897194 scopus 로고
    • The binding site for C1q on IgG
    • Duncan, A. R., and G. Winter. 1988. The binding site for C1q on IgG. Nature 332:738.
    • (1988) Nature , vol.332 , pp. 738
    • Duncan, A.R.1    Winter, G.2
  • 5
    • 0027828448 scopus 로고
    • The binding of C1q to immunoglobulins
    • Painter, R. H. 1993. The binding of C1q to immunoglobulins. Behring Inst. Mitt. 93:131.
    • (1993) Behring Inst. Mitt. , vol.93 , pp. 131
    • Painter, R.H.1
  • 6
    • 0015894484 scopus 로고
    • Complete amino acid sequence of the mu heavy chain of a human IgM immunoglobulin
    • Putnam, F. W., G. Florent, C. Paul, T. Shinoda, and A. Shimizu. 1973. Complete amino acid sequence of the mu heavy chain of a human IgM immunoglobulin. Science 182:287.
    • (1973) Science , vol.182 , pp. 287
    • Putnam, F.W.1    Florent, G.2    Paul, C.3    Shinoda, T.4    Shimizu, A.5
  • 7
    • 0642315750 scopus 로고
    • Tertiary structure of the constant regions of immunoglobulins in relation to their function
    • Feinstein, A., and N. E. Richardson. 1981. Tertiary structure of the constant regions of immunoglobulins in relation to their function. Monogr. Allergy 17:28.
    • (1981) Monogr. Allergy , vol.17 , pp. 28
    • Feinstein, A.1    Richardson, N.E.2
  • 8
    • 0020629997 scopus 로고
    • A monoclonal antibody with specificity for murine mu heavy chain which inhibits the formation of antigen-specific direct IgM plaques
    • Leptin, M., and F. Melchers. 1983. A monoclonal antibody with specificity for murine mu heavy chain which inhibits the formation of antigen-specific direct IgM plaques. J. Immunol. Methods 59:53.
    • (1983) J. Immunol. Methods , vol.59 , pp. 53
    • Leptin, M.1    Melchers, F.2
  • 9
    • 0021255402 scopus 로고
    • Monoclonal antibodies specific for murine IgM. I. Characterization of antigenic determinants on the four constant domains of the μ heavy chain
    • Leptin, M., M. J. Potash, R. Grutzmann, C. Heusser, M. Shulman, G. Kohler, and F. Melchers. 1984. Monoclonal antibodies specific for murine IgM. I. Characterization of antigenic determinants on the four constant domains of the μ heavy chain. Eur. J. Immunol. 14:534.
    • (1984) Eur. J. Immunol. , vol.14 , pp. 534
    • Leptin, M.1    Potash, M.J.2    Grutzmann, R.3    Heusser, C.4    Shulman, M.5    Kohler, G.6    Melchers, F.7
  • 10
    • 0016827673 scopus 로고
    • C1 fixation and classical complement pathway activation by a fragment of the Cμ4 domain of IgM
    • Hurst, M. M., J. E. Volanakis, R. M. Stroud, and J. C. Bennett. 1975. C1 fixation and classical complement pathway activation by a fragment of the Cμ4 domain of IgM. J. Exp. Med. 142:1322.
    • (1975) J. Exp. Med. , vol.142 , pp. 1322
    • Hurst, M.M.1    Volanakis, J.E.2    Stroud, R.M.3    Bennett, J.C.4
  • 11
    • 0023770759 scopus 로고
    • C1 binding by murine IgM: The effect of a Pro-to-Ser exchange at residue 436 of the μ-chain
    • Wright, J. F., M. J. Shulman, D. E. Isenman, and R. H. Painter. 1988. C1 binding by murine IgM: the effect of a Pro-to-Ser exchange at residue 436 of the μ-chain. J. Biol. Chem. 263:11221.
    • (1988) J. Biol. Chem. , vol.263 , pp. 11221
    • Wright, J.F.1    Shulman, M.J.2    Isenman, D.E.3    Painter, R.H.4
  • 12
    • 0025372203 scopus 로고
    • C1 binding by mouse IgM: The effect of abnormal glycosylation at position 402 resulting from a serine to asparagine exchange at residue 406 of the μ-chain
    • Wright, F. J., M. J. Shulman, D. E. Isenman, and R. H. Painter. 1990. C1 binding by mouse IgM: the effect of abnormal glycosylation at position 402 resulting from a serine to asparagine exchange at residue 406 of the μ-chain. J. Biol. Chem. 265:10506.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10506
    • Wright, F.J.1    Shulman, M.J.2    Isenman, D.E.3    Painter, R.H.4
  • 13
    • 0028258180 scopus 로고
    • Mapping of amino acid residues in the Cμ3 domain of mouse IgM important in macromolecular assembly and complement-dependent cytolysis
    • Arya, S. K., F. Chen, S. Spycher, D. E. Isenman, M. J. Shulman, and R. H. Painter. 1994. Mapping of amino acid residues in the Cμ3 domain of mouse IgM important in macromolecular assembly and complement-dependent cytolysis. J. Immunol. 152:1206.
    • (1994) J. Immunol. , vol.152 , pp. 1206
    • Arya, S.K.1    Chen, F.2    Spycher, S.3    Isenman, D.E.4    Shulman, M.J.5    Painter, R.H.6
  • 14
    • 0014768883 scopus 로고
    • The fixation of complement and the activated first component (C1) of complement by complexes formed between antibody and divalent hapten
    • Hyslop, N. E. J., R. R. Dourmashkin, N. M. Green, and R. R. Porter. 1970. The fixation of complement and the activated first component (C1) of complement by complexes formed between antibody and divalent hapten. J. Exp. Med. 131:783.
    • (1970) J. Exp. Med. , vol.131 , pp. 783
    • Hyslop, N.E.J.1    Dourmashkin, R.R.2    Green, N.M.3    Porter, R.R.4
  • 15
    • 0016017730 scopus 로고
    • Effect of antigen binding on the properties of antibody
    • Metzger, H. 1974. Effect of antigen binding on the properties of antibody. Adv. Immunol. 18:169.
    • (1974) Adv. Immunol. , vol.18 , pp. 169
    • Metzger, H.1
  • 16
    • 0018156557 scopus 로고
    • The effects of antigen on antibodies: Recent studies
    • Metzger, H. 1978. The effects of antigen on antibodies: recent studies. Contemp. Top. Mol. Immunol. 7:119.
    • (1978) Contemp. Top. Mol. Immunol. , vol.7 , pp. 119
    • Metzger, H.1
  • 17
    • 0019021430 scopus 로고
    • Dimeric, trimeric and tetrameric complexes of immunoglobulin G fix complement
    • Wright, J. K., J. Tschopp, J. C. Jaton, and J. Engel. 1980. Dimeric, trimeric and tetrameric complexes of immunoglobulin G fix complement. Biochem. J. 187:775.
    • (1980) Biochem. J. , vol.187 , pp. 775
    • Wright, J.K.1    Tschopp, J.2    Jaton, J.C.3    Engel, J.4
  • 18
    • 0028985495 scopus 로고
    • Addition of a μ-tailpiece to IgG results in polymeric antibodies with enhanced effector functions including complement-mediated cytolysis by IgG4
    • Smith, R. I. F., M. J. Coloma, and S. L. Morrison. 1995. Addition of a μ-tailpiece to IgG results in polymeric antibodies with enhanced effector functions including complement-mediated cytolysis by IgG4. J. Immunol. 154:2226.
    • (1995) J. Immunol. , vol.154 , pp. 2226
    • Smith, R.I.F.1    Coloma, M.J.2    Morrison, S.L.3
  • 19
    • 0014693139 scopus 로고
    • Conformation of the free and antigen-bound IgM antibody molecules
    • Feinstein, A., and E. A. Munn. 1969. Conformation of the free and antigen-bound IgM antibody molecules. Nature 224:1307.
    • (1969) Nature , vol.224 , pp. 1307
    • Feinstein, A.1    Munn, E.A.2
  • 21
    • 0642285245 scopus 로고
    • C1q binding properties of monomer and polymer forms of mouse IgM μ chain variants: Pro544Gly, and Pro434Ala
    • Taylor, B., J. F. Wright, S. Arya, D. E. Isenman, M. J. Shulman, and R. H. Painter. 1994. C1q binding properties of monomer and polymer forms of mouse IgM μ chain variants: Pro544Gly, and Pro434Ala. J. Immunol. 145:925.
    • (1994) J. Immunol. , vol.145 , pp. 925
    • Taylor, B.1    Wright, J.F.2    Arya, S.3    Isenman, D.E.4    Shulman, M.J.5    Painter, R.H.6
  • 22
    • 0023890929 scopus 로고
    • C1q binding by a high affinity anti-fluorescein murine monoclonal IgM antibody and monomeric subunits
    • Swanson, S. M., M. A. Dombrink-Kurtzman, and E. W. Voss, Jr. 1988. C1q binding by a high affinity anti-fluorescein murine monoclonal IgM antibody and monomeric subunits. Mol. Immunol. 25:545.
    • (1988) Mol. Immunol. , vol.25 , pp. 545
    • Swanson, S.M.1    Dombrink-Kurtzman, M.A.2    Voss Jr., E.W.3
  • 23
    • 26344478141 scopus 로고
    • Studies on the interaction between IgM and C1q using domain-shuffled hybrid IgM/IgG antibodies
    • Chen, F. H., D. E. Isenman, M. J. Shulman, S. Arya, and R. H. Painter. 1994. Studies on the interaction between IgM and C1q using domain-shuffled hybrid IgM/IgG antibodies. FASEB J. 8:A.
    • (1994) FASEB J. , vol.8
    • Chen, F.H.1    Isenman, D.E.2    Shulman, M.J.3    Arya, S.4    Painter, R.H.5
  • 24
    • 0028902638 scopus 로고
    • Structure and function of several anti-dansyl chimeric antibodies formed by domain interchanges between human IgM and mouse IgG2b
    • Poon, P. H., S. L. Morrison, and V. N. Schumaker. 1995. Structure and function of several anti-dansyl chimeric antibodies formed by domain interchanges between human IgM and mouse IgG2b. J. Biol. Chem. 270:8571.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8571
    • Poon, P.H.1    Morrison, S.L.2    Schumaker, V.N.3
  • 25
    • 0018305685 scopus 로고
    • Mutations affecting immunoglobulin light chain secretion by myeloma cells. I. Functional analysis by cell fusion
    • Mosmann, T. R., R. Baumal, and A. R. Williamson. 1979. Mutations affecting immunoglobulin light chain secretion by myeloma cells. I. Functional analysis by cell fusion. Eur. J. Immunol. 9:511.
    • (1979) Eur. J. Immunol. , vol.9 , pp. 511
    • Mosmann, T.R.1    Baumal, R.2    Williamson, A.R.3
  • 26
    • 0023741405 scopus 로고
    • Homologous recombination can restore normal immunoglobulin production in a mutant hybridoma cell line
    • Baker, M. D., N. Pennell, L. Bosnoyan, and M. J. Shulman. 1988. Homologous recombination can restore normal immunoglobulin production in a mutant hybridoma cell line. Proc. Natl. Acad. Sci. USA 85:6432.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6432
    • Baker, M.D.1    Pennell, N.2    Bosnoyan, L.3    Shulman, M.J.4
  • 28
    • 0025314153 scopus 로고
    • Isotype modulation of idiotypic expression in recombinant isotypic variants of MOPC 315
    • Rinfret, A., C. Horne, H. Boux, A. Marks, K. J. Dorrington, and M. Klein. 1990. Isotype modulation of idiotypic expression in recombinant isotypic variants of MOPC 315. J. Immunol. 145:925.
    • (1990) J. Immunol. , vol.145 , pp. 925
    • Rinfret, A.1    Horne, C.2    Boux, H.3    Marks, A.4    Dorrington, K.J.5    Klein, M.6
  • 30
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680.
    • (1970) Nature , vol.227 , pp. 680
    • Laemmli, U.K.1
  • 31
    • 84911733382 scopus 로고
    • Generation of humoral responses: Secondary immunization to nitrophenyl haptens
    • B. B. Mishell and R. I Mishell, eds. W. H. Freeman, San Francisco
    • Mishell, R. I. 1980. Generation of humoral responses: secondary immunization to nitrophenyl haptens. In Selected Methods in Cellular Immunology. B. B. Mishell and R. I Mishell, eds. W. H. Freeman, San Francisco.
    • (1980) Selected Methods in Cellular Immunology
    • Mishell, R.I.1
  • 32
    • 0019472804 scopus 로고
    • Purification and radiolabelng of human C1
    • Tenner, A. J., P. H. Lesavre, and N. R. Cooper. 1981. Purification and radiolabelng of human C1. J. Immunol. 127:648.
    • (1981) J. Immunol. , vol.127 , pp. 648
    • Tenner, A.J.1    Lesavre, P.H.2    Cooper, N.R.3
  • 33
    • 0022512382 scopus 로고
    • A region of the immunoglobulin μ-heavy chain necessary for forming pentameric IgM
    • Baker, M. D., G. E. Wu, W. M. Toonem, H. Murialdo, A. Davis, and M. J. Shulman. 1986. A region of the immunoglobulin μ-heavy chain necessary for forming pentameric IgM. J. Immunol. 137:1724.
    • (1986) J. Immunol. , vol.137 , pp. 1724
    • Baker, M.D.1    Wu, G.E.2    Toonem, W.M.3    Murialdo, H.4    Davis, A.5    Shulman, M.J.6
  • 34
    • 0021803124 scopus 로고
    • Efficiency of activation of complement by antihapten antibodies at the red cell surface: Effect of patchy vs random distribution of hapten
    • Circolo, A., P. Battista, and T. Borsos. 1985. Efficiency of activation of complement by antihapten antibodies at the red cell surface: effect of patchy vs random distribution of hapten. Mol. Immunol. 22:207.
    • (1985) Mol. Immunol. , vol.22 , pp. 207
    • Circolo, A.1    Battista, P.2    Borsos, T.3
  • 35
    • 0021991644 scopus 로고
    • Segmental flexibility of the C1q subcomponent of human complement and its possible role in the immune response
    • Hanson, D. C., R. C. Siegel, and V. N. Schumaker. 1985. Segmental flexibility of the C1q subcomponent of human complement and its possible role in the immune response. J. Biol. Chem. 260:3576.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3576
    • Hanson, D.C.1    Siegel, R.C.2    Schumaker, V.N.3
  • 36
    • 0022557568 scopus 로고
    • A molecular mechanism for the activation of the first component of complement by immune complexes
    • Schumaker, V. N., D. C. Hanson, E. Kilchherr, M. L. Phillips, and P. H. Poon. 1986. A molecular mechanism for the activation of the first component of complement by immune complexes. Mol. Immunol. 23:557.
    • (1986) Mol. Immunol. , vol.23 , pp. 557
    • Schumaker, V.N.1    Hanson, D.C.2    Kilchherr, E.3    Phillips, M.L.4    Poon, P.H.5
  • 37
    • 0023137465 scopus 로고
    • A functional model of the human C1 complex
    • Arlaud, G. J., M. G. Colomb, and J. Gagnon. 1987. A functional model of the human C1 complex. Immunol. Today 8:106.
    • (1987) Immunol. Today , vol.8 , pp. 106
    • Arlaud, G.J.1    Colomb, M.G.2    Gagnon, J.3
  • 38
    • 0023879177 scopus 로고
    • The distortive mechanism for the activation of complement component C1 supported by studies with a monoclonal antibody against the "arms" of C1q
    • Hoekzema, R., M. Martens, M. C. Brouwer, and C. E. Hack. 1988. The distortive mechanism for the activation of complement component C1 supported by studies with a monoclonal antibody against the "arms" of C1q. Mol. Immunol. 25:485.
    • (1988) Mol. Immunol. , vol.25 , pp. 485
    • Hoekzema, R.1    Martens, M.2    Brouwer, M.C.3    Hack, C.E.4
  • 39
    • 0013799985 scopus 로고
    • Hemolysin titration based on fixation of the activated first component of complement: Evidence that one molecule of hemolysin suffices to sensitize an erythrocyte
    • Borsos, T., and H. J. Rapp. 1965. Hemolysin titration based on fixation of the activated first component of complement: evidence that one molecule of hemolysin suffices to sensitize an erythrocyte. J. Immunol. 95:559.
    • (1965) J. Immunol. , vol.95 , pp. 559
    • Borsos, T.1    Rapp, H.J.2
  • 40
    • 0001321260 scopus 로고
    • Complement fixation on cell surfaces by 19S and 7S antibody
    • Borsos, T., and H. J. Rapp. 1965. Complement fixation on cell surfaces by 19S and 7S antibody. Science 150:505.
    • (1965) Science , vol.150 , pp. 505
    • Borsos, T.1    Rapp, H.J.2
  • 41
    • 0014291397 scopus 로고
    • Fixation of C′ and C′ 1a by rabbit γ-G- and γ-M-antibodies with particulate and soluble antigens
    • Ishizaka, T., T. Tada, and K. Ishizaka. 1968. Fixation of C′ and C′ 1a by rabbit γ-G- and γ-M-antibodies with particulate and soluble antigens. J. Immunol. 100:1145.
    • (1968) J. Immunol. , vol.100 , pp. 1145
    • Ishizaka, T.1    Tada, T.2    Ishizaka, K.3
  • 42
    • 0015953119 scopus 로고
    • Thermodynamics of hapten binding to MOPC 315 and MOPC 460 mouse myeloma proteins
    • Johnston, M. F. M., B. G. Barisas, and J. M. Sturtevant. 1974. Thermodynamics of hapten binding to MOPC 315 and MOPC 460 mouse myeloma proteins. Biochemistry 13:390.
    • (1974) Biochemistry , vol.13 , pp. 390
    • Johnston, M.F.M.1    Barisas, B.G.2    Sturtevant, J.M.3
  • 43
    • 0024552303 scopus 로고
    • Structural requirements for IgM assembly and cytolytic activity: Effect of mutations in the oligosaccharide acceptor site at Asn402
    • Muraoka, S., and M. J. Shulman. 1989. Structural requirements for IgM assembly and cytolytic activity: effect of mutations in the oligosaccharide acceptor site at Asn402. J. Immunol. 142:695.
    • (1989) J. Immunol. , vol.142 , pp. 695
    • Muraoka, S.1    Shulman, M.J.2
  • 44
    • 0023765625 scopus 로고
    • Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q
    • Bindon, C. I., G. Hale, M. Bruggemann, and H. Waldmann. 1988. Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q. J. Exp. Med. 168:127.
    • (1988) J. Exp. Med. , vol.168 , pp. 127
    • Bindon, C.I.1    Hale, G.2    Bruggemann, M.3    Waldmann, H.4
  • 45
    • 0022358372 scopus 로고
    • Immunoglobulin M possesses two binding sites for complement subcomponent C1q, and soluble 1:1 and 2:1 complexes are formed in solution at reduced ionic strength
    • Poon, P. H., M. L. Phillips, and V. N. Schumaker. 1985. Immunoglobulin M possesses two binding sites for complement subcomponent C1q, and soluble 1:1 and 2:1 complexes are formed in solution at reduced ionic strength. J. Biol. Chem. 260:9357.
    • (1985) J. Biol. Chem. , vol.260 , pp. 9357
    • Poon, P.H.1    Phillips, M.L.2    Schumaker, V.N.3
  • 46
    • 0026009904 scopus 로고
    • Solution structure of human and mouse immunoglobulin M by synchrotron X-ray scattering and molecular graphics modeling: A possible mechanism for complement activation
    • Perkins, S. J., A. S. Nealis, B. J. Sutton, and A. Feinstein. 1991. Solution structure of human and mouse immunoglobulin M by synchrotron X-ray scattering and molecular graphics modeling: a possible mechanism for complement activation. J. Mol. Biol. 221:1345.
    • (1991) J. Mol. Biol. , vol.221 , pp. 1345
    • Perkins, S.J.1    Nealis, A.S.2    Sutton, B.J.3    Feinstein, A.4
  • 47
    • 0024386066 scopus 로고
    • Models for the C1 complex determined by physical techniques
    • Perkins, S. J. 1989. Models for the C1 complex determined by physical techniques. Behring Inst. Mitt. 84:129.
    • (1989) Behring Inst. Mitt. , vol.84 , pp. 129
    • Perkins, S.J.1
  • 49
    • 0025006089 scopus 로고
    • The biological effects of IgM hexamer formation
    • Randall, T. D., L. B. King, and R. B. Corley. 1990. The biological effects of IgM hexamer formation. Eur. J. Immunol. 20:1971.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 1971
    • Randall, T.D.1    King, L.B.2    Corley, R.B.3


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