A review of patient outcomes in pharmacological studies from the psychiatric literature, 1966-1993

Science and Engineering Ethics

Volumn 3, Issue 4, 1997, Pages 395-406

  Shamoo, Adil E ^a   Irving, Dianne N ^b   Langenberg, Patricia ^c  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b De Sales School of Theology ^*  (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

Clinical research ethics; Informed and proxy consent; Institutional Review Boards; Integrity of research data; Protocol design; Relapses; Schizophrenia; Suicides

Indexed keywords

PSYCHOTROPIC AGENT;

ARTICLE; BIOMEDICAL AND BEHAVIORAL RESEARCH; COMPARATIVE STUDY; EMPIRICAL APPROACH; EMPIRICAL RESEARCH; HUMAN; HUMAN EXPERIMENT; INFORMED CONSENT; INTERPERSONAL COMMUNICATION; MENTAL CAPACITY; MENTAL HEALTH THERAPIES; MENTAL PATIENT; METHODOLOGY; RESEARCH; RESEARCH SUBJECT; SCHIZOPHRENIA; STATISTICS; SUICIDE; TREATMENT OUTCOME; TREATMENT WITHDRAWAL; UNITED KINGDOM; UNITED STATES;

BIOMEDICAL AND BEHAVIORAL RESEARCH; EMPIRICAL APPROACH; MENTAL HEALTH THERAPIES;

DISCLOSURE; EMPIRICAL RESEARCH; GREAT BRITAIN; HUMAN EXPERIMENTATION; HUMANS; INFORMED CONSENT; MENTAL COMPETENCY; MENTALLY ILL PERSONS; PSYCHOTROPIC DRUGS; RESEARCH; RESEARCH DESIGN; RESEARCH SUBJECTS; SCHIZOPHRENIA; STATISTICS; SUICIDE; TREATMENT OUTCOME; UNITED STATES; WITHHOLDING TREATMENT;

EID: 0031240296     PISSN: 13533452     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11948-997-0043-1     Document Type: Review

References (56)

1. Shamoo, A.E., Keay, T.J. (1996) Ethical Concerns About Relapse Studies. Cambridge Quarterly of Healthcare Ethics 5:373-386.
2. Shamoo, A.E., Irving, D.N. (1993) Accountability in research using persons with mental illness. Accountability in Research 3:1-17.
3. Shamoo, A.E. (1994) Our responsibilities toward persons with mental illness as human subjects in research. J. of the California Alliance for the Mentally Ill 5(5):14-16.
4. Irving, D.N. (1994) Psychiatric research. Reality check. J of the California Alliance for the Mentally Ill 5(5):42-44.
5. Shamoo, A.E. (1996) Editor, "Ethics in Neurobiological Research with Human Subjects", The Baltimore Conference on Ethics held January 7-9, 1995, Baltimore, Maryland, pp. 1-337, Gordon and Breach Science Publishers, New York, N.Y.
6. Journal of the California Alliance for the Mentally Ill. 'Ethics in neurobiological research with human subjects' (series of articles) 1994;5(5):1-69.
7. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
8. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
9. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
10. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
11. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
12. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
13. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
14. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
15. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
16. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
17. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
18. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath,
19. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
20. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
21. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
22. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
23. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
24. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
25. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
26. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
27. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
28. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
29. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting side-effects of antipsychotic drugs. International Clinical Psychopharmacology 2(1):55-67; McKane, J.P., Robinson, A.D., Wiles, D.H., McCreadie, R.G. & Stirling, G.S. (1987) Haloperidol decanoate V. fluphenazine decanoate as maintenance therapy in chronic schizophrenic in-patients. British Journal of Psychiatry 151:333-6; Johnson, D.A., Ludlow, JM., Street, K. & Taylor, R.D. (1987) Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilized out-patients with schizophrenia. British Journal of Psychiatry 151:634-8; Nishikawa, T., Tanaka, M., Tsuda, A., Koga, I., & Uchida, Y. (1989) Prophylactic effects of neuroleptics in symptoms-free schizophrenia: A comparative dose-response study of timiperone and sulpiride. Biol. Psychiatry 25:861-866; Soni, S.D., Sampath, G., Shah, A. & Krska, J. (1992) Rationalizing neuroleptic polypharmacy in chronic schizophrenics: Effects of changing to a single depot preparation. Acta Psychiatr. Scand. 85:354-359.
30. Johnson, D.A.W. (1976) The Duration of Maintenance Therapy in Chronic Schizophrenia. Acta Psychiat. Scand. 53:298-301; Andrews, P, Hall, J.N. and Snaith, R.P. (1976) A Controlled Trial of Phenothiazine Withdrawal in Chronic Schizophrenic Patients. Brit. J. Psychiat 128:451-455; Stevens, B. (1976) The social value of fluphenazine deconate. Acta psychiat. belg. 76:792-804; Kingstone, E., Grof, P., Furlong, W., Jacques, W., Vire, L. & Daigle, L. (1977) Penfluridol, A Peroral Long-Acting Neuroleptic, for the Maintenance Treatment of Schizophrenic Patients Who Relapse. J. Clinical Pharmacology 17:252-258; Dencker, S.J., Lepp, M. & Malm, U. (1980) Clopenthixol and flupenthixol depot preparations in outpatient schizophrenia, I. A one year double-blind study of clophenthixol deconate and flupenthixol palmitate, Acta Psychiat. Scand. (Suppl) 279:10-28; Dencker, S.J., Lepp, M. & Malm, U. (1980) Do schizophrenic well adapted in the community need neuroleptics? Depot neuroleptic withdrawal study. Acta Psychiatrica Scandinavica - Supplementum 279:64-76; McCredie, R.G., Dingwall, J.M., Wiles, D.H. & Heykants, J.J. (1980) Intermittent pimozide versus fluphenazine decanoate as maintenance. British Journal of Psychiatry 137:510-517; Capstick, N. (1980) Long-term fluphenazine decanoate maintenance dosage requirements of chronic schizophrenic patients. Acta Psychiatrica Scandinavica 61(3):256-262; Zander, K.J., Fischer, B., Zimmer, R. & Ackenheil, M. (1981) Long-term neuroleptic treatment of chronic schizophrenic patients: Clinical and biochemical effects of withdrawal. Psychopharmacology 73(1):43-47; Wistedt, B. (1981) A depot neuroleptic withdrawal study. A controlled study of the clinical effects of the withdrawal of depot fluphenazine decanoate and depot flupenthixol decanoate in chronic schizophrenic patients. Acta Psychiatric Scandinavica 64(1):65-84; Cheung, H.K. (1981) Schizophrenic fully remitted on neuroleptics for 3-5 years - to stop or continue drugs? British Journal of Psychiatry 138:490-494; Odejide, O.A. & Aderounmu, A.F. (1982) Double-blind placebo substitution: withdrawal of fluphenazine decanoate in schizophrenic patients. Journal of clinical psychiatry 43(5):195-196; McCreadie, R., Mackie, M., Morrison, D. & Kidd, J. (1982) Once weekly pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia. British Journal of Psychiatry 140:280-286; Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry 44(10):369-71; Johnson, D.A., Pasterski, G., Ludlow, J.M., Street, K. & Taylor, R.D. (1983) The discontinuance of maintanence neuroleptic therapy in chronic schizophrenic patients: drug and social consequences. Acta Psychiatrica Scandinavica 67(5):339-52; Perenyi, A., Kuncz, E. & Bagdy, G. (1985) Early relapse after sudden withdrawal or dose reduction of clozapine (Letter). Psychopharmacology 86(1-2):244; Frecska, E., Perenyi, A., Bagdy, G. & Revai, K. (1985) CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment. Psychiatry Research 16(3):221-6; McMillan, D.E., Fody, E.P., Couch, L., Harrison, R.H., Newton, J.E. & Reese, W.G. (1986) Drug holidays and serum haloperidol levels in schizophrenic patients. Journal of Clinical Psychiatry 47(7):373-4; Dencker SJ, Malm U, Lepp M. Schizophrenic relapse after drug withdrawal is predictable. Acta Psyhiatrica Scandinavica, 1986;73(2):181-5; Fleischhacker, WW., Stuppack, C., Barnas, C., Unterweger, B. & Hinterhuber, H. (1987) Low-dose zotepine in the maintenance treatment of schizophrenia. Pharmacopsychiatry 20(1 Spec No):61-3; Menkes, D.B., Clarkson, H.O., Caradoc-Davies, G. & Mullen, P.E. (1987) Anticholinergic equivalents and parkinsonism: a model for predicting
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