Memory and behavior: A second generation of genetically modified mice

Current Biology

Volumn 7, Issue 9, 1997, Pages

  Mayford, Mark ^a   Mansuy, Isabelle M ^b   Muller, Robert U ^c   Kandel, Eric R ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b New York State Psychiatric Institute ^*  (United States)

^c SUNY Downstate Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0031240002     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(06)00287-9     Document Type: Review

References (48)

1. Squire LR, Zola SM: Memory, memory impairment, and the medial temporal lobe. Cold Spring Harb Symp 1996, 61:183-185.
2. Carew TJ: Molecular enhancement of memory formation. Neuron 1996, 16:5-8.
3. Martin KC, Kandel ER: Cell adhesion molecules, CREB, and the formation of new synaptic connections. Neuron 1996, 17:567-570.
4. Tully T, Bolwig G, Christensen J, Connolly J, DelVecchio M, DeZazzo J, Dubnau J, Jones G, Pinto S, Regulski M, et al.: A return to genetic dissection of memory in Drosophila. Cold Spring Harb Symp 1996, 61:207-218.
5. Scoville WB, Milner B: Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry 1957, 20:11-21.
6. Burwell RD, Suzuki WA, Insausti R, Amaral DG: Some observations on the perirhinal and parahippocampal cortices in the rat, monkey and human brains. In Perception, Memory and Emotion: Frontiers in Neuroscience, Edited by Ono T, McNaughton BL, Molotchnikoff S, Rolls ET, Nishigo H. Pergamon Press: Elsevier Science Ltd; 1996:
7. Bliss TV, Lomo T: Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J Physiol 1973, 232:331-356.
8. Bliss TV, Collingridge GL: A synaptic model of memory: long-term potentiation in the hippocampus. Nature 1993, 361:31-39.
9. Morris RG, Garrud P, Rawlins JN, O'Keefe J: Place navigation impaired in rats with hippocampal lesions. Nature 1982, 297:681-683.
10. O'Keefe J, Dostrovsky J: The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. Brain Res 1971, 34:171-175.
11. Silva AJ, Stevens CF, Tonegawa S, Wang Y: Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science 1992, 257:201-206.
12. Silva AJ, Paylor R, Wehner JM, Tonegawa S: Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science 1992, 257:206-211.
13. Grant SG, O'Dell TJ, Karl KA, Stein PL, Soriano P, Kandel ER: Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice [see comments]. Science 1992, 258:1903-1910.
14. Mayford M, Baranes D, Podsypanina K, Kandel ER: The 3′-untranslated region of CaMKIIα is a cis-acting signal for the localization and translation of mRNA in dendrites. Proc Natl Acad Sci USA 1996, 93:13250-13255.
15. Kojima N, Wang J, Mansuy IM, Grant SGN, Mayford M, Kandel ER: Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene. Proc Natl Acad Sci USA 1997, 34:4761-4765.
16. Mayford M, Bach ME, Huang YY, Wang L, Hawkins RD, Kandel ER: Control of memory formation through regulated expression of CaMKIIα transgene. Science 1996, 274:1678-1683.
17. Tsien JZ, Chen DF, Gerber D, Tom C, Mercer EH, Anderson DJ, Mayford M, Kandel ER, Tonegawa S: Subregion- and cell type- restricted gene knockout in mouse brain. Cell 1996, 87:1317-1326.
18. Gu H, Marth JD, Orban PC, Mossmann M, Rajewsky K: Deletion of a DNA polymerase beta gene segment in T cells using cells using type-specific gene targeting. Science 1994, 265:103-106.
19. Lakso M, Sauer B, Mosinger B Jr, Lee EJ, Manning RW, Yu S-H, Mulder KL, Westphal H: Targeted oncogene activation by site- specific recombination in transgenic mice. Proc Natl Acad Sci USA 1992, 89:6232-6236.
20. Abremski K, Hoess R: Bacteriophage P1 site-specific recombination. Purification and properties of the Cre recombinase protein. J Biol Chem 1984, 259:1509-1514.
21. Sauer B, Henderson N: Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc Natl Acad Sci USA 1988, 85:5166-5170.
22. Tsien JZ, Huerta PT, Tonegawa S: The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 1996, 87:1327-1338.
23. Huang YY, Kandel ER, Varshavsky L, Brandon EP, P M, Idzerda RL, McKnight GS, Bourtchouladze R: A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning. Cell 1995, 83:1211-1222.
24. Gossen M, Bujard H: Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992, 89:5547-5551.
25. Furth PA, St Onge L, Boger H, Gruss P, Gossen M, Kistner A, Bujard H, Hennighausen L: Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc Natl Acad Sci USA 1994, 91:9302-9306.
26. Malinow R, Schulman H, Tsien RW: Inhibition of postsynaptic PKC or CaMKIIα blocks induction but not expression of LTP. Science 1989, 245:862-866.
27. Malenka RC, Kauer JA, Perkel DJ, Mauk MD, Kelly PT, Nicol RA, Waxham MN: An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation. Nature 1989, 340:554-557.
28. 2+-triggered molecular switch. Cell 1986, 44:861-870.
29. Lisman JE: The CaMKIIα hypothesis for the storage of synaptic memory. Trends Neurosci 1994, 17:406-412.
30. 2+/calmodulin-dependent protein kinase II. Identification of a regulatory autophosphorylation site adjacent to the inhibitory and calmodulin-binding domains. J Biol Chem 1988, 263:13486-13489.
31. 2+-independent activity. Neuron 1988, 1:593-604.
32. 2+-independent activity. Proc Natl Acad Sci USA 1988, 85:6331-6341.
33. 2+/calmodulin-dependent protein kinase. J Neurosci 1989, 9:2020-2032.
34. 2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate. J Biol Chem 1989, 264:16759-16763.
35. 2+ independent for functional studies. Biochemistry 1990, 29:1679-1684.
36. Mayford M, Wang J, Kandel ER, O'Dell TJ: CaMKIIα regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell 1995, 81:891-904.
37. Bach ME, Hawkins RD, Osman M, Kandel ER, Mayford M: Impairment of spatial but not contextual memory in CaMKIIα mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency. Cell 1995, 81:905-915.
38. Staubli U, Lynch G. Stable hippocampal long-term potentiation elicited by 'theta' pattern stimulation. Brain Res 1987, 435:227-234.
39. Huerta PT, Lisman JE: Bidirectional synaptic plasticity induced by a single burst during cholinergic theta oscillation in CA1 in vitro. Neuron 1995, 15:1053-1063.
40. Bostook E, Muller RU, Kubie JL: Experience-dependent modifications of hippocampal place cell firing. Hippocampus 1991, 1:193-205.
41. Muller RU: A quarter of a century of place cells. Neuron 1996, 17:813-822.
42. Rotenberg A, Mayford M, Hawkins RD, Kandel ER, Muller RU: Mice expressing activated CaMKII lack low frequency LTP and do not form stable place cells in the CA1 region of the hippocampus. Cell 1996, 87:1351-1361.
43. Muller RU, Kubie JL, Ranck JB: Spatial firing patterns of hippocampal complex-spike cells in a fixed environment. J Neurosci 1987, 7:1935-1950.
44. McHugh TJ, Blum K, Tsien JZ, Tonegawa S, Wilson MA: Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice. Cell 1996, 87:1339-1349.
45. Gossen M, Freundlieb S, Bender G, Muller G, Hillen W, Bujard H: Transcriptional activation by tetracyclines in mammalian cells. Science 1995, 268:1766-1769.
46. Kistner A, Gossen M, Zimmermann F, Jerecie J, Ullmer C, Lubbert H, Bujard H: Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci USA 1996, 93:10933-10938.
47. Feil R, Brocard J, Mascrez B, LeMeur M, Metzger D, Chambon P: Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci USA 1996, 93:10887-108890.
48. No D, Yao T-P, Evans RM: Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc Natl Acad Sci USA 1996, 93:3346-3351.