A novel approach to stabilization of protein drugs in poly(lactic-co-glycolic acid) microspheres

American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

Volumn 38, Issue 2, 1997, Pages 604-605

  Li, Jia Kui ^a   Wang, Nuo ^a   Wu, Xue Shen ^a,b  

^a LONG ISLAND UNIVERSITY   (United States)

^b POLYTECHNIC UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CARBOXYLIC ACIDS; CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; EMULSIONS; ENCAPSULATION; GELATION; PARTICLES (PARTICULATE MATTER); PROTEINS;

GELATIN NANOPARTICLES; OIL IN OIL EMULSION; POLYMERIC MICROSPHERES; PROTEIN DRUGS;

COPOLYMERS;

EID: 0031232564     PISSN: 00323934     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Article

References (4)

1. Cohen, S.; Yoshioka, T.; Lucarelli, M.; Hwang, L. H.; Langer, R. Controlled delivery systems for proteins based on poly(lactic/glycolic acid) nucrospheres. Pharm. Res. 1991, 8, 713-720.
2. Csemus, V. J., Sxende, B., Schally, A. V. Release of peptides from sustained delivery systems (microcapsules and microparticles) in vivo. Intern. J. Peptide Protein Res. 1990, 35, 557-565.
3. Sluzky, V.; Tamada, J. A.; Klibanov, A. M.; Langer, R. Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces. Proc. Natl. Acad. Sci. USA 1991, 88, 9377-9381.
4. J. K. Li. N. Wang, and X. S. Wu. Gelatin nanoencapsulation of protein/peptide/ drugs using an emulsifier-free emulsion method. J. Microencapsulation in press.