Involvement of interleukin-1β, nerve growth factor, and prostaglandin-E2 in the hyperalgesia induced by intraplantar injections of low doses of thymulin

Brain, Behavior, and Immunity

Volumn 11, Issue 3, 1997, Pages 185-200

  Safieh Garabedian, Bared ^a   Kanaan, Salim A ^a   Jalakhian, Raffy H ^a   Jabbur, Suhayl J ^a   Saadé, Nayef E ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

Hyperalgesia; Interleukin 1 ; Nerve growth factor; Neuroimmunology; PGE2; Thymulin

Indexed keywords

DEXAMETHASONE; INDOMETACIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; NERVE GROWTH FACTOR; POLYCLONAL ANTIBODY; PROSTAGLANDIN E2; THYMULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HOT PLATE TEST; HYPERALGESIA; MALE; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; TAIL FLICK TEST;

EID: 0031231441     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1006/brbi.1997.0491     Document Type: Article

References (33)

1. Aloisi, A. M., Porro, C. A., Cavazzuti, M., Baraldi, P., & Carli, G. (1993). 'Mirror pain' in the formalin test: Behavioral and 2-deoxyglucose studies. Pain 55, 267-273.
2. Bach, J-F. (1983). Thymulin (FTS-Zn). Clinics Immunol. Allergy 3, 133-156.
3. Bordigoni, P., Bene, M. C., Faure, G., Donner, C., Janot, M., Dardenne, M., Duheille, J., & Olive, D. (1984). Allogenic bone marrow transplantation in man: In vitro activity of FTS-Zn on T cell markers and functions. Br. J. Haematol. 58, 661-669.
4. Cunha, F. Q., Poole, S., Lorenzetti, B. B., & Ferreira, S. H. (1992). The pivotal role of tumor necrosis factor α in the development of inflammatory hyperalgesia. Br. J. Pharmacol. 107, 660-664.
5. Dardenne, M., Pléau, J. M., Nabarra, B., Lefranchie, P., Derrien, M., Choay, J., & Bach, J. F. (1977). Structural isolation of circulating thymic factor. A peptide isolated from pig serum. 1. Isolation and purification. J. Biol. Chem. 252, 8040-8044.
6. Davis, A. J., & Perkins, M. N. (1994). The involvement of bradykinin B1 and B2 receptor mechanisms in cytokine-induced mechanical hyperalgesia in the rat. Br. J. Pharmacol. 113, 63-68.
7. Donnerer, J., Schuligoi, R., & Stein, C. (1992). Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: Evidence for a regulatory function of nerve growth factor in vivo. Neuroscience 49, 693-698.
8. Ferreira, S. H. (1972). Prostaglandins, aspirin like drugs and analgesia. Nature 240, 200-203.
9. Ferreira, S. H., Lorenzetti, B. B., Bristow, A. F., & Poole, S. (1988). Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue. Nature 334, 698-700.
10. Flower, R. J., & Rothwell, N. J. (1994). Lipocotin-1: Cellular mechanisms and clinical relevance. Trends Pharmacol. Sci. 15, 71.
11. Gualde, N., Rigaud, M., & Bach, J. F. (1982). Stimulation of prostaglandin synthesis by the serum factor (FTS). Cell Immunol. 70, 362-366.
12. Hingtgen, C. M., Waite, K. J., & Vasko, M. R. (1995). Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3′,5′-cyclic monophosphate transduction cascade. J. Neurosci. 15, 5411-5419.
13. Incefy, G. S., Mertelsmann, R., Yata, K., Dardenne, M., Bach, J. F., & Good, R. A. (1980). Induction of differentiation of markers in human marrow T-cell precursors by the synthetic serum thymic factor (FTS). Clin. Exp. Immunol. 40, 396-400.
14. Jonaikat, G. M. (1993). Neural-immune interactions in sympathetic ganglia. Trends Neurosciences 10, 419-423.
15. Kanaan, S. A., Saadé, N. E., Haddad, J. J., Abdelnoor, A. M., Atweh, S. F., Jabbur, S. J., & Safieh-Garabedian, B. (1996). Endotoxin-induced local inflammation and hyperalgesia in rats and mice: A new model for inflammatory pain. Pain 66, 373-379.
16. Lee, S. W., Tsou, A. P., Chan, H., Thomas, J., Petrie, K., Eugui, E. M., & Allison, A. C. (1988). Glucocorticoids selectively inhibit the transcription of the interleukin-1 beta and decrease the stability of interleukin-1 beta mRNA. Proc. Natl. Acad. Sci. USA 85, 1204-1208.
17. Lewin, G. R., & Mendell, L. M. (1993). Nerve growth factor and nociception. Trends Neurosciences 16, 353-358.
18. Lewin, G. R., Ritter, A. M., & Mendell, L. M. (1993). Nerve growth factor induced hyperalgesia in the neonatal and adult rat. J. Neurosci. 13, 2136-2148.
19. Lindholm, D., Hengerer, B., Heumann, R., Caroll, P., & Thoenen, H. (1990). Glucocorticoid hormones negatively regulate nerve growth factor expression in vivo and cultured rat fibroblasts. Eur. J. Neurosci. 2, 795-801.
20. Mitchell, J. A., Akarasereenont, P., Themermann, C., Flower, R. J., & Vane, J. R. (1993). Selectivity of non steroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. USA 90, 11693-11697.
21. Muzzioli, M., Mocchegiani, E., Bressani, N., Bevilacqua, P., & Fabris, N. (1992). In vitro restoration by thymulin of NK activity of cells from old mice. Int. J. Immunopharmacol. 14, 57-61.
22. 193-195. Br. J. Pharmacol. 106, 489-492.
23. 2. Eur. J. Immunol. 15, 548-552.
24. Safieh, B., Kendall, M. D., Norman, J. C., Metreau, E., Dardenne, M., Bach, J. F., & Pléau, J. M. (1990). A new radioimmunoassay for the thymic peptide thymulin, and its application for measuring thymulin in blood samples. J. Immunol. Meth. 127, 255-262.
25. Safieh-Garabedian, B., Ahmed, K., Khamashta, M. A., & Hughes, G. R. V. (1993). Thymulin modulates cytokine release by peripheral blood mononuclear cells: A comparison between healthy volunteers and patients with systemic lupus erythematosus. Int. Arch. Allergy Immunol. 101, 126-131.
26. Safieh-Garabedian, B., Poole, S., Allchorne, A., Winter, J., & Woolf, C. J. (1995). Contribution of interleukin-1β to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br. J. Pharmacol. 115, 1265-1275.
27. Safieh-Garabedian, B., Jalakhian, R. H., Saadé, N. E., Haddad, J. J., Jabbur, S. J., & Kanaan, S. A. (1996). Thymulin reduces hyperalgesia induced by peripheral endotoxin injection in rats and mice. Brain Res. 717, 179-183.
28. 2. J. Neuroimmunol. 73, 162-168.
29. Taktak, Y. S., Selkirk, S., Bristow, A. F., Carpenter, A., Ball, C., Rafferty, B., & Poole, S. (1991). Assay of pyrogens by interleukin-6 release from monocyte cell lines. J. Pharm. Pharmacol. 43, 578-582.
30. Vane, J. R., Mitchell, J. A., Appleton, I., Tomlinson, A., Bishop-Bailey, D., Croxtall, J., & Willoughby, D. A. (1994). Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc. Natl. Acad. Sci. USA 91, 2046-2050.
31. Weskamp, G., & Otten, U. (1987). An enzyme-linked immunoassay for nerve growth factor (NGF): A tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues. J. Neurochem. 48, 1779-1786.
32. Woolf, C. J., Safieh-Garabedian, B., Ma, Q-P., Crilly, P., & Winter, J. (1994). Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience 62, 327-331.
33. Zimmerman, M. (1983). Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16, 109-110.