Structural determination of a dimeric side-product accompanying dihydropyrazine preparation

Acta Chemica Scandinavica

Volumn 51, Issue 9, 1997, Pages 938-941

  Gopal, Damodaragounder ^a   Macikenas, Dainius ^a   Sayre, Lawrence M ^a   Protasiewicz, John D ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PYRAZINE DERIVATIVE;

ARTICLE; AUDIOVISUAL EQUIPMENT; CHEMISTRY; CONFORMATION; MASS FRAGMENTOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL CHEMISTRY; SYNTHESIS; ULTRAVIOLET SPECTROPHOTOMETRY; X RAY CRYSTALLOGRAPHY;

CHEMISTRY, PHYSICAL; CRYSTALLOGRAPHY, X-RAY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MAGNETIC RESONANCE IMAGING; MODELS, STRUCTURAL; MOLECULAR CONFORMATION; PYRAZINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0031227794     PISSN: 0904213X     EISSN: None     Source Type: Journal    
DOI: 10.3891/acta.chem.scand.51-0938     Document Type: Article

References (8)

1. Akiyama, T., Enomoto, Y. and Shibamoto, T. J. Agric. Food Chem. 26 (1978) 1176.
2. Peer, H. G. and Van der Heijden, A. Recl. Trav. Chim. Pays-Bas 8 (1969) 1335.
3. Mason, J. P. Chimia 21 (1967) 510.
4. Flament, I. and Stoll, M. Helv. Chim. Acta 50 (1967) 1754.
5. Felder, E., Pitre, D., Boveri, S. and Grabitz, E. B. Chem. Ber. 100 (1967) 555.
6. While this manuscript was being reviewed, a recent literature report appeared (Yamaguchi, T., Eto, M., Watanabe, K., Kashige, N. and Harano, K. Chem. Pharm. Bull. 44 (1996) 1977) that includes, among other topics, the generation of dimer 2 from dihydropyrazine 1 and essentially the same crystal formulation of 2. However, the mechanism invoked to explain this transformation differs from ours, and the spectral characterizations we obtained were not reported.
7. SHELXTL, version 5, Siemens Analytical X-Ray Instruments, Madison, WI 1994.
8. Bürgi, H.-B. and Dunitz, J. D., Eds., Structure Correlation, VCH, New York 1994, Vol. 2.