Comparison of p53 expression in proximal and distal gastric cancer: Histopathologic correlation and prognostic significance

Annals of Surgical Oncology

Volumn 4, Issue 6, 1997, Pages 470-474

  Tang, Huihuan ^b   Hokita, Shuichi ^a   Che, Xiangming ^a   Baba, Masamichi ^a   Aridome, Kuniaki ^a   Kijima, Fumio ^a   Tanabe, Gen ^a   Takao, Sonshin ^a   Aikou, Takashi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Gastric cancer; p53 overexpression; Prognosis

Indexed keywords

MONOCLONAL ANTIBODY; PROTEIN P53; TUMOR MARKER;

ADULT; AGED; ARTICLE; BIOSYNTHESIS; CANCER INVASION; COMPARATIVE STUDY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; STOMACH TUMOR; SURVIVAL RATE;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PROGNOSIS; RETROSPECTIVE STUDIES; STOMACH NEOPLASMS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031227474     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02303670     Document Type: Review

References (25)

1. Levine AJ, Momand J, Finlay GA. The p53 tumour suppressor gene. Nature 1991;351:453-6.
2. Vogelstein B, Kinzler KW. p53 function and dysfunction. Cell 1992;70:523-6.
3. Bartek J, Iggo R, Gannon J, Lane DP. Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene 1990;5:893-9.
4. Barnes DM, Dublin EA, Fisher CJ, Levision DA, Millis PR. Immunohistochemical detection of p53 protein in mammary carcinoma: an important new independent indicator of prognosis. Hum Pathol 1993;24:469-76.
5. Akiko S, David EF. p53 in life and death. Clin Cancer Res 1996; 2:435-40.
6. Fonseca L, Yonemura Y, De-Aretxabala X, Yamaguchi A, Niwa K, Miyazaki L. p53 detection as a prognostic factor in early gastric cancer. Oncology 1994;51:485-90.
7. Joypaul BV, Hopwood D, Newman EL, et al. The prognostic significance of the accumulation of p53 tumour suppressor geneprotein in gastric adenocarcinoma. Br J Cancer 1994;69:943-6.
8. Uchino S, Noguchi M, Hirota T, et al. High incidence of nuclear accumulation of p53 portion in gastric cancer. Jpn J Clin Oncol 1992;22:225-31.
9. Hongyo T, Gregory SB, Domenico P, Christopher MW, Andrea A, Monica G. Mutations of the K-ras and p53 genes in gastric adenocarcinomas from a high-incidence region around Florence, Italy. Cancer Res 1995;55:2665-72.
10. Thor AD, Moor DH, Edgerton SM, et al. Accumulation of p53 tumour suppressor gene protein: an independent marker of prognosis in breast cancer. J Natl Cancer Inst 1992;84:845-55.
11. Quinlan DC, Davidson AG, Summers CL, Warden HE, Doshi AM. Accumulation of p53 protein correlates with poor prognosis in human lung cancer. Cancer Res 1992;52:4828-31.
12. Sun XF, Carstensen JM, Zhang H, et al. Prognosis significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma. Lancet 1992;340:1369-73.
13. Bell SM, Scott N, Cross D, et al.: Prognosis value of p53 overexpression and C-Ki-ras gene mutations in colorectal cancer. Gastroenterology 1993;104:57-64.
14. Sarbia M, Forschen R, Borchard F, Horstmann O, Willeas R, Gabbet HE. p53 protein expression and prognosis in squamous cell carcinoma of the esophagus. Cancer 1994;74:2218-23.
15. Joypaul BV, Newman SL, Hopwood D, et al. Expression of p53 protein in normal dysplastic and malignant gastric mucosa; an immunohistochemical study. J Pathol 1993;170:279-83.
16. Yonezawa S, Tachikawa T, Shin S, Sato E. Sialosyl-In antigen: its distribution in normal human tissues and expression in adenocarcinoma. Am J Clin Pathol 1992;98:161-7.
17. Schneider BG, Hilsenbeck SG, Hensel CH, et al. p53 mutation in gastric and colorectal cancers Texas Hispanics versus Anglos. Virchows Arch 1994;424:187-93.
18. Martin HM, Filipe MI, Morris RW, Lane DP, Silvestre F. p53 expression and prognosis in gastric carcinoma. Int J Cancer 1992; 50:859-62.
19. Starzynska T, Markiewski M, Domagala W, et al. The clinical significance of p53 accumulation in gastric carcinoma. Cancer 1996;77:2005-11.
20. Gabbert HE, Muller W, Schneiders A, Meier S, Hommel G. The relationship of p53 expression to the prognosis of 418 patients with gastric carcinoma. Cancer 1995;76:720-6.
21. Tahara E, Semba S, Tahara H. Molecular biological observations in gastric cancer. Semin Oncol 1996;23:307-15.
22. Sano T, Tsujno T, Yoshida K, Nakayama H, Haruma K, Ito H, Nakamura K. Frequent loss of heterozygosity on chromosomes 1q, 5q and 17p in human gastric carcinomas. Cancer Res 1991;51: 2926-31.
23. Uchino S, Noguchi M, Ochiai A, Saito T, Kobayashi M, Hirohashi S. p53 mutation in gastric cancer, a genetic model for carcinogenesis is common to gastric and colorectal cancer. Int J Cancer 1993;54:759-64.
24. Gomyo Y, Osaki M, Kaibara N, Ito H. Numerical aberration and point mutation of p53 gene in human gastric intestinal metaplasia and well-differentiated adenocarcinoma, analysis by fluorescence in situ hybridization (FISH) and PCR-SSCP. Int J Cancer 1996; 66:594-9.
25. Schneider PM, Casson AG, Levin B, et al. Mutations of p53 in Barrett's esophagus and Barrett's cancer, a prospective study of ninety-eight cases. J Thorac Cardiovasc Surg 1996;111:323-33.