mRNA expression of insulin-like growth factor-I (IGF-I) is suppressed and those of IGF-II and IGF-binding protein-1 are constantly expressed in the endometrium during use of an intrauterine levonorgestrel system

Molecular Human Reproduction

Volumn 3, Issue 9, 1997, Pages 749-754

  Rutanen, E M ^a   Salmi, A ^a   Nyman, T ^b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

Author keywords

Endometrium; IGFBP 1; IGFs; Levonorgestrel; mRNA

Indexed keywords

CONTRACEPTIVE AGENT; LEVONORGESTREL; MESSENGER RNA; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN C;

ADULT; ARTICLE; COMPARATIVE STUDY; DECIDUA; DRUG ANTAGONISM; DRUG EFFECT; ENDOMETRIUM; FEMALE; GENE EXPRESSION; GENETICS; HUMAN; INTRAUTERINE CONTRACEPTIVE DEVICE; METABOLISM; NORTHERN BLOTTING; PREGNANCY; TIME;

ADULT; BLOTTING, NORTHERN; CONTRACEPTIVE AGENTS, FEMALE; DECIDUA; ENDOMETRIUM; FEMALE; GENE EXPRESSION; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; INTRAUTERINE DEVICES, MEDICATED; LEVONORGESTREL; PREGNANCY; RNA, MESSENGER; TIME FACTORS;

EID: 0031226055     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/3.9.749     Document Type: Article

References (43)

1. Andersson, K., Mattsson, L.-A., Rybo, G. and Stadberg, E. (1992a) Intrauterine release of levonorgestrel - a new way of adding progestogen in hormone replacement therapy. Obstet. Gynecol., 79, 963-967.
2. Andersson, K., Batar I. and Rybo, G. (1992b) Return to fertility after removal of a levonorgestrel-releasing intrauterine device and Nova-T. Contraception, 46, 575-584.
3. Andersson, J.K. and Rybo, G. (1990) Levonorgestrel-releasing intrauterine device in the treatment of menorrhagia. Br. J. Obstet. Gynaecol., 97, 690-694.
4. Barbosa, I., Bakos, O., Olsson, S.-E. et al (1990) Ovarian function during use of a levonorgestrel-releasing IUD. Contraception. 42, 51-66.
5. Barbu, V. and Dautry, F. (1989) Northern blot normalization with a 28S rRNA oligonucleotide probe. Nucleic Acids Res . 17, 7115.
6. Bell, G I., Merryweather, J.P., Sanchez-Pescador, R. et al. (1984) Sequence of a cDNA clone encoding human preproinsulin-like growth factor II. Nature, 310, 775-781.
7. Bell, S.C., Patel, S.R., Jackson, J.A. and Waites, G.T. (1988) Major secretory protein of human decidualized endometrium in pregnancy is an insulinlike growth factor-binding protein. J. Endocrinol., 118, 317-328.
8. Brinkman, A., Groffen, C.A.H., Kortleve, D.J. et al. (1988) Organization of the gene encoding the insulin-like growth factor binding protein IBP-1. Biochem . Biophys. Res. Comm., 157, 898-907.
9. Chomczynski, P. and Sacchi N. (1987) Single-step method of RNa isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
10. Dallenbach-Hellweg, G.G. (1987) The histopathology of the endometnum. In Histopathology of the Endometrium Springer Verlag, Berlin, pp. 158-200.
11. Fraser, I.S., Hickey, M , and Song, J (1996) A comparison of mechanisms underlying disturbances of bleeding caused by spontanous dysfunctional uterine bleeding or hormonal contraception. Hum. Reprod., 11 (Suppl. 2). 165-178.
12. Gao, J.-G., Zhu, H.H., Fan, J. et al (1995) Progestin and antiprogesun differentially regulate the expression of insulin-like growth factors (IGF-I and IGF-II) messenger ribonucleic acid in human endometrial stromal cells. Biol. Reprod., 53, 355-360.
13. Giudice, L.C., Dsupin, B.A., Jin, I.H. et al. (1993) Differential expression of messenger ribonucleic acids encoding insulin-like growth factors and their receptors in human uterine endometrium and decidua. J. Clin. Endocrinol. Metab.,16, 1115-1122.
14. Ignar-Trowbridge, D.M., Pimentel, M, Parker, M.G. et al. (1996) Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol. Endocrinology, 137, 1735-1744.
15. Irwin, J.C., Utian, W.H. and Eckert, R.L. (1991) Sex steroids and growth factors differentially regulate the growth and differentiation of cultured human endometrial stromal cells. Endocrinology; 129, 385-2392.
16. Johannisson E (1987) Mechanism of action of intrauterine devices: biochemical changes. Contraception, 36, 11-22.
17. Julkunen, M.,Koistinen, R., Suikkari, A-M. et al. (1990) Identification by hybridization histochemistry of human endometrial cells expressing mRNA encoding a uterine β-lactoglobulin homologue and insulin-like growth factor-binding protein-1. Mol. Endocrinol., 4, 700-707.
18. Lopez, M.F., Dikkes, P., Zurakowski, D. and Villa-Komaroff, L. (1996) Insulin-like growth factor II affects the appearance and glycogen content of glycogen cells in the murine placenta. Endocrinology, 137, 2100-2108.
19. Luukkainen, T. and Toivonen, J. (1995) Levonorgestrel-releasing IUD as a method of contraception with therapeutic properties. Contraception, 52, 269-276.
20. Marsh, M.M., Findlay, J.K. and Salamonsen, L.A. (1996) Endothelin and menstruation. Hum. Reprod., 11 (Suppl. 2) 83-89.
21. Murphy, L. and Ghahary, A. (1990) Uterine insulin-like growth factor-1: regulation of expression and its role in estrogen-induced uterine proliferation. Endocr. Rev., 11, 443-453.
22. Nilsson, C.G., Luukkainen, T. and Arko, H. (1978) Endometrial morphology of women using a D-norgestrel-releasing mtrauterine device. Fertil. Steril., 29, 397-401.
23. Nilsson, C-G., Lähteenmaki, P. and Luukkainen, T. (1984) Ovarian function in amenorrhoeic and menstruating users of a levonorgestrel-releasing intrauterine device. Fertil. Steril, 1, 52-55.
24. Noyes, R.W., Hertig, A.T. and Rock, J. (1950) Dating of endometrial biopsy. Fertil Steril., 1, 3-25.
25. Pekonen, F, Nyman, T., Lähteenmaki, P. et al. (1992) Intrauterine progestin induces continuous insulin-like growth factor binding protein-1 production in the human endometrium. J. Clin. Endocrinol. Metab., 75, 660-664.
26. Pekonen, F, Nyman, T., Ammalä, M. and Rutanen, E.-M. (1995) Decreased expression of messenger RNAs encoding endothelin receptors and neutral endopeptidase 24.11 in endometnal cancer. Br. J. Cancer, 71, 59-63.
27. Ponte, P, Ng, S-Y, Engel, J et al. (1984) Evolutionary conservation in the translated regions of actin mRNAs: DNA sequence of a human β-actin cDNA. Nucleic Acid Res.. 12, 1687-1696.
28. Raudaskoski, T.H., Lahti, E.I., Kauppila, A.J. et al. (1995) Transdermal estradiol with a levonorgestrel-releasmg intrauterine device: clinical and endometnal responses. Am. J. Obstet. Gynecol. 172, 114-119.
29. Rotwein, P. (1986) Two insulin-like growth factor I messenger RNAs are expressed in human liver. Proc Natl. Acad. Sci. USA. 83, 77-81.
30. Rotwein, P., Pollock, K.M., Didier, D.K. and Krivi, G G (1986) Organization and sequence of the human insulin-like growth factor I gene alternative RNA processing produces two insulin-like growth factor I precursor peptides. J. Biol. Chem., 261, 4828-4832.
31. Rutanen, E.-M. (1992) Insulin-like growth factor binding protein-1. Semin. eprod. Endocrinol., 10, 154-163.
32. Rutanen, E.-M., Pekonen, F. and Mäkinen, T. (1988) Soluble 34K binding protein inhibits the binding of insulin-like growth factor I to its receptors in human secretory phase endometrium: evidence for autocrine/paracrine regulation of growth factor action. J. Clin. Endocrinol. Metab., 66, 173-180.
33. Shen, S.-J., Daimon, M. and Wang, C.-Y. (1988) Isolation of the insulin-like growth factor II cDNA with a unique 5′ untranslated region from human placenta. Proc. Natl. Acad. Sci. USA, 85, 1947-1951.
34. Sheppard, B.L. (1987) Endometrial morphological changes in IUD users: a review. Contraception, 36, 1-10.
35. Shimasaki, S. and Ling, N. (1992) Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5, and -6). Prog. Growth Factor Res., 3, 243-266.
36. Silverberg, S.G., Haukkamaa, M., Arko, H. et al. (1992) Endometrial morphology during long-term use of levonorgestrel-releasing intrauterine devices. Int. J. Gynecol. Pathol., 5, 235-241.
37. Smith, S.K. (1996) Vascular endothelial growth factor and the endometrium. Hum. Reprod., 11 (Suppl. 2), 56-61.
38. Song, J.Y and Fraser, I.S. (1995) Effects of progestogens on human endometrium. Obstet. Gynecol. Surv., 50, 385-394.
39. Stewart, C.E. and Rotwein, P. (1996) Insulin-like growth factor-II is an autocrine survival actor for differentiating myoblasts. J. Biol. Chem., 271, 11330-11338
40. Suhonen, S., Haukkamaa, M., Holmstrom, T. et al. (1996) Endometrial response to hormone replacement therapy as assessed by expression of insulin-like growth factor-binding protein-1 in the endometrium. Fertil. Steril., 65, 776-782.
41. Suvanto-Luukkonen, E., Sundström, H., Penttinen, J. et al. (1995) Insulin-like growth factor-binding protein-1: a biochemical marker of endometrial response to progestin during hormone replacement therapy. Maturitas, 22, 255-262.
42. Umayahara, Y., Kawamori, R., Watada, H. et al. (1994) Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer. J. Biol. Chem., 269, 16433-16442.
43. Zhou, J., Dsupin, B A., Giudice, L.C. and Bondy, C. A. (1994) Insulin-like growth factor system gene expression in human endometrium during the menstrual cycle. J. Clin. Endocrinol. Metab., 79, 1723-1734.