Screening of a small set of random peptides: A new strategy to identify synthetic peptides that mimic epitopes

Journal of Molecular Recognition

Volumn 10, Issue 5, 1997, Pages 217-224

  Slootstra, J W ^a   Puijk, W C ^a   Ligtvoet, G J ^a   Kuperus, D ^a   Schaaper, W M M ^a   Meloen, R H ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Epitope; Mimics; Small diversity libraries

Indexed keywords

ANTIGEN STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE; PROTEIN PROTEIN INTERACTION; TRANSMISSIBLE GASTROENTERITIS VIRUS;

TRANSMISSIBLE GASTROENTERITIS VIRUS;

EID: 0031225120     PISSN: 09523499     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1099-1352(199709/10)10:5<217::aid-jmr371>3.0.co;2-%23     Document Type: Article

References (25)

1. Clackson, T. and Wells, J. A. (1994). In vitro selection from protein and peptide libraries. Trends Biotechnol. 12, 173-184.
2. Coursaget, P., Depril, N., Buisson, Y., Molinie, C. and Roue, R. (1994). Hepatitis type E in a French population: detection of anti-HEV by a synthetic peptide-based enzyme-tinked immunosorbent assay. Res. Virol. 145, 51-57.
3. Felici, F., Luzzago, A., Folgori, A. and Cortese, R. (1993). Mimicking of discontinuous epitopes by phage-displayed peptides, II. Selection of clones recognized by a protective monoclonal antibody against the Bordetella pertussis toxin from phage peptide libraries. Gene 128, 21-27.
4. Folgori, A., Tafi, R., Meola, A., Felici, F., Galfre, G., Cortese, R., Monaci, P. and Nicosia, A. (1994). A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. EMBO J. 13, 2236-2243.
5. Gebauer, F., Posthumus, W. P. A., Correa, I., Sune, C., Smerdou, C., Sanchez, C. M., Lenstra, J. A., Meloen, R. H. and Enjuanes, L. (1991). Residues involved in the antigenic sites of Transmissible Gastroenteritis coronavirus S glycoprotein, Virology 183, 225-238.
6. Geysen, H. M., Meloen, R. H. and Barteling, S. J. (1984). Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid. Proc. Natl Acad. Sci. USA 81, 3998-4002.
7. van Grunsven, W. M., Spaan, W. J. and Middeldorp, J. M. (1994). Localization and diagnostic application of immunodominant domains of the BFRF3-encoded Epstein-Sarr virus capsid protein. J. Infect. Dis. 170, 13-19.
8. Houghten, R. A. (1986). Facile determination of exact amino acid involvement in peptide antige/monoclonal antibody interactions. In Protides of the Biological Fluids, Proceedings of the 34th Colloquium, ed. by H. Peeters, pp. 19-22. Pergamon Press, Oxford.
9. Kobs-Conrad, S., Lee, H., DiGeorge, A. M. and Kaumaya, T. P. (1993). Engineered topographic determinants with alpha-beta, beta-alpha-beta, and beta-alpha-beta-alpha topologies show high affinity binding to native protein antigen (Lactate dehydrogenase-C4). J. Biol. Chem. 268, 25285-25295.
10. Ladner, R. C. (1995). Constrained peptides as binding entities. Trends Biotechnol. 13, 426-430.
11. Lang, E., Szendrei, G. I., Lee, V. M. and Otvos Jr., L. (1994). Spectroscopic evidence that monoclonal antibodies recognize the dominant conformation of medium-sized synthetic peptides. J. Immunol. Methods 170, 103-115.
12. Langeveld, J. P. M., Casal, J. I., Osterhaus, A. D. M. E., Cortes, E., Swart de, R., Vela, C., Dalsgaard, K., Puijk, W. C., Schaaper, W. M. M. and Meloen, R. H. (1994). First peptide vaccine providing protection against viral infection in the target animal: studies of canine parvovirus in dogs. J. Virology 68, 4506-4513.
13. Lenstra, J. A., Erkens, J. H. F., Langeveld, J. P. M., Posthumus W. P. A., Meloen, R. H., Gebauer F., Correa, I., Enjuanes, L. and Stanley, K. K. (1992). Isolation of sequences from a random-sequence expression library that mimic viral epitopes. J. Immunol. Methods 152, 149-157.
14. Mattioli, S., Imberti, L., Stellini, R. and Primi, D. (1995) Mimicry of the immunodominant conformation-dependent antigenic site of hepatitis A virus by motifs selected from synthetic peptide libraries. J. Virol. 69, 5294-5299.
15. McConnel, S. J., Kendall, M. L., Reilly, T. M. and Hoess, R. H. (1994). Constrained peptide libraries as a tool for finding mimotopes. Gene 151, 115-118.
16. McLafferty, M. A., Kent, R. B., Ladner, R. C. and Markland, W. (1993). M13 bacteriophage displaying disulfide-constrained microproteins. Gene 128, 29-36.
17. Meloen R. H., Casal, J. I., Dalsgaard K. and Langeveld J. P. M. (1995). Synthetic peptide vaccines: Success at last. Vaccine 13, 885-886.
18. Meola, A., Delmastro, P., Monaci, P., Luzzago, A., Nicosia, A., Felici, F., Cortese, R. and Galfre, G. (1995). Derivation of vaccines from mimotopes. Immunologic properties of human hepatitis B virus surface antigen mimotopes displayed on filamentous phage. J. Immunol. 154, 3162-3172.
19. Miceli, R. M., Graaf de, M. E. and Fischer, H. D. (1994). Two-stage selection of sequences from a random phage display library delineates both core residues and permitted structural range within an epitope. J. Immunol. Methods 167, 279-287.
20. Motti, C., Nuzzo, M., Meola, A., Galfre, G., Felici, F., Cortese, R., Nicosia, A. and Monaci, P. (1994). Recognition by human sera and immunogenicity of HBsAg mimotopes selected from an M13 phage display library. Gene 146, 191-198.
21. Pinilla, C., Appel, J. R. and Houghten, R. A. (1993). Functional importance of amino acid residues making up peptide antigenic determinants. Mol. Immunol. 30, 577-585.
22. Slootstra, J. W., Puijk, W. C. Ligtvoet, G. J., Langeveld, J. P. M. and Meloen, R. H. (1995). Structural aspects of antibody-antigen interaction revealed through small random peptide libraries. Molecular Diversity 1, 87-96.
23. Slootstra, J. W., Kuperus, D., Plückthun, A. and Meloen, R. H. (1996). Identification of new tag sequences with differential and selective recognition properties for the anti-FLAG monoclonal antibodies M1, M2 and M5. Molecular Diversity 2, 156-164.
24. Steward, M. W., Stanley, C. M. and Obeid, O. E. (1995). A mimotope from a solid-phase peptide library induces a measles virus-neutralizing and protective antibody response. J. Virol. 69, 7668-7673.
25. Stoute, J. A., Ballou, W. R., Kolodny, N., Deal, C. D., Wirtz, R. A. and Lindler, L. E. (1995). Induction of humoral immune response against Plasmodium falciparum sporozoites by immunization with a synthetic peptide mimotope whose sequence was derived from screening a filamentous phage epitope library. Infection and Immunity 63, 933-939.