메뉴 건너뛰기




Volumn 19, Issue 9-10, 1997, Pages 569-572

Oral dosing of rats with OM-89 results in the appearance of specific OM- 89 antibodies of the IgG2(2a) isotype: Possible significance in the treatment of rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2A; OM 89;

EID: 0031224892     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0192-0561(97)00053-2     Document Type: Conference Paper
Times cited : (2)

References (28)
  • 2
    • 0025962975 scopus 로고
    • Biological activity of bacterial surface components: Immunogenicity and immunomodulatory properties of a bacterial extract from Escherichia coli
    • Bessler, W. G., Beck, P., Konetznick, U., Loleit, M., Sedelmeier, E., Hoffmann, P., Strecker, M. & Stocklin, S. (1991) Biological activity of bacterial surface components: immunogenicity and immunomodulatory properties of a bacterial extract from Escherichia coli. Arzneim Forsch./ Drug Res., 41(1), 274-279.
    • (1991) Arzneim Forsch./ Drug Res. , vol.41 , Issue.1 , pp. 274-279
    • Bessler, W.G.1    Beck, P.2    Konetznick, U.3    Loleit, M.4    Sedelmeier, E.5    Hoffmann, P.6    Strecker, M.7    Stocklin, S.8
  • 3
    • 0025038041 scopus 로고
    • A myvobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic
    • Billingham, M. E. J., Careny, S., Butler, R. & Colston, M. J. (1990) A myvobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic. J. exp. Med., 171, 339-344.
    • (1990) J. Exp. Med. , vol.171 , pp. 339-344
    • Billingham, M.E.J.1    Careny, S.2    Butler, R.3    Colston, M.J.4
  • 4
    • 0023736776 scopus 로고
    • Enhancement of the humoral reponse and resistance to bacterial infection in mice by oral administration of a bacterial immunomodulator (OM-89)
    • Bosch, A., Benedi, V. J., Pares, R. & Jofre, J. (1988) Enhancement of the humoral reponse and resistance to bacterial infection in mice by oral administration of a bacterial immunomodulator (OM-89). Immunopharmacol. Immunotoxicol., 10, 333-343.
    • (1988) Immunopharmacol. Immunotoxicol. , vol.10 , pp. 333-343
    • Bosch, A.1    Benedi, V.J.2    Pares, R.3    Jofre, J.4
  • 5
    • 0024236431 scopus 로고
    • Effects of two bacterial extracts, OM-89 and Broncho-Vaxom, on IL-1 release and metabolic activity of a human macrophage cell line
    • Bottex, C., Cristaw, B., Corazza, J. L., Mougin, B. & Fontagnes, R. (1988) Effects of two bacterial extracts, OM-89 and Broncho-Vaxom, on IL-1 release and metabolic activity of a human macrophage cell line. Int. J. Immunother., 4, 203-312.
    • (1988) Int. J. Immunother. , vol.4 , pp. 203-312
    • Bottex, C.1    Cristaw, B.2    Corazza, J.L.3    Mougin, B.4    Fontagnes, R.5
  • 6
    • 0025130854 scopus 로고
    • Action of a mycotoxin (Diacetoxyscirpenol) on the immune response of the mouse-interaction with an immunodulator (OM-89)
    • Bottex, C., Martin, A. & Fontages, R. (1990) Action of a mycotoxin (Diacetoxyscirpenol) on the immune response of the mouse-interaction with an immunodulator (OM-89). Immunopharmacol. Immunotoxicol., 12, 311-321.
    • (1990) Immunopharmacol. Immunotoxicol. , vol.12 , pp. 311-321
    • Bottex, C.1    Martin, A.2    Fontages, R.3
  • 7
    • 0024560450 scopus 로고
    • OM-8980 in rheumatoid arthritis: A six month double blind placebo controlled multicentre study
    • Brackertz, D. & Vischer, T. L. (1986) OM-8980 in rheumatoid arthritis: a six month double blind placebo controlled multicentre study. J. Rheumatol., 16, 19-23.
    • (1986) J. Rheumatol. , vol.16 , pp. 19-23
    • Brackertz, D.1    Vischer, T.L.2
  • 8
    • 0026567911 scopus 로고
    • A case for chaperones in antigen processing
    • DeNagel, D. C. & Pierce, S. K. (1992) A case for chaperones in antigen processing. Immunol. Today, 13(3), 86-89.
    • (1992) Immunol. Today , vol.13 , Issue.3 , pp. 86-89
    • DeNagel, D.C.1    Pierce, S.K.2
  • 9
    • 0002302894 scopus 로고
    • Comparison of two disease modifying antirheumatic drugs - Auranofin and OM-89 on adjuvant arthritis in the rat
    • Farine, J. C. & Farre, A. J. (1988) Comparison of two disease modifying antirheumatic drugs - Auranofin and OM-89 on adjuvant arthritis in the rat. Int. J. Immunopath. Pharm., 1, 39-44.
    • (1988) Int. J. Immunopath. Pharm. , vol.1 , pp. 39-44
    • Farine, J.C.1    Farre, A.J.2
  • 10
    • 0028026941 scopus 로고
    • Rapamycin inhibits production of cytotoxic but not non-cytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats
    • Ferraresso, M., Tian, L., Ghobrial, R., Strepkowski, S. M. & Kahan, B. D. (1994) Rapamycin inhibits production of cytotoxic but not non-cytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats. J. Immunol., 153, 3307-3318.
    • (1994) J. Immunol. , vol.153 , pp. 3307-3318
    • Ferraresso, M.1    Tian, L.2    Ghobrial, R.3    Strepkowski, S.M.4    Kahan, B.D.5
  • 11
    • 0000624379 scopus 로고
    • Immunopharmacological investigation with the orally administered immunostimulant OM-89 in the mouse
    • (eds. Bizzini, B. and Bonmassar, E.), Pythagora Press, Rome
    • Fontagnes, R., Burkhart, M. F., Bottex, C. & Farine, J. C. (1988). Immunopharmacological investigation with the orally administered immunostimulant OM-89 in the mouse. In Advances in Immunmodulation (eds. Bizzini, B. and Bonmassar, E.), pp. 139-145. Pythagora Press, Rome.
    • (1988) Advances in Immunmodulation , pp. 139-145
    • Fontagnes, R.1    Burkhart, M.F.2    Bottex, C.3    Farine, J.C.4
  • 12
    • 0025892041 scopus 로고
    • Effects of a hydrosoluble bacterial extract of Eschericia coli (OM-89) on cytokine production by peripheral blood mononuclear cells from healthy subjects and patients with rheumatoid arthritis
    • Franchimont, N., Vrinddts-Gevaert, Y., Collette, Y. & Franchimont, P. (1991) Effects of a hydrosoluble bacterial extract of Eschericia coli (OM-89) on cytokine production by peripheral blood mononuclear cells from healthy subjects and patients with rheumatoid arthritis. Scand. J. Rheumatol., 20, 196-203.
    • (1991) Scand. J. Rheumatol. , vol.20 , pp. 196-203
    • Franchimont, N.1    Vrinddts-Gevaert, Y.2    Collette, Y.3    Franchimont, P.4
  • 13
    • 0017870165 scopus 로고
    • Two distinct mechanisms of immune suppression by antibody
    • Hoffmann, M. K. & Kappler, J. W. (1978) Two distinct mechanisms of immune suppression by antibody. Nature, 272, 64-65.
    • (1978) Nature , vol.272 , pp. 64-65
    • Hoffmann, M.K.1    Kappler, J.W.2
  • 14
    • 0028567838 scopus 로고
    • Prevention of diabetes in BB rats by an E. coli extract (OM-89)
    • Kiesal, U., Farine, J. C. & Kolb, H. (1994) Prevention of diabetes in BB rats by an E. coli extract (OM-89). Int. J. Immunopath. Pharm., 7, 193-199.
    • (1994) Int. J. Immunopath. Pharm. , vol.7 , pp. 193-199
    • Kiesal, U.1    Farine, J.C.2    Kolb, H.3
  • 15
    • 0030066630 scopus 로고    scopus 로고
    • A 71-kD heat-shock protein (hsp) from M. tuberculosis has modulatory effects on experimental rat arthritis
    • Kingston, A. E., Hicks, C. A., Colston, M. J. & Billingham, M. E. J. (1996) A 71-kD heat-shock protein (hsp) from M. tuberculosis has modulatory effects on experimental rat arthritis. Clin. exp. Immunol., 103, 77-82.
    • (1996) Clin. Exp. Immunol. , vol.103 , pp. 77-82
    • Kingston, A.E.1    Hicks, C.A.2    Colston, M.J.3    Billingham, M.E.J.4
  • 16
    • 0029920574 scopus 로고    scopus 로고
    • Mechanisms of action of intravenous immune globulin in immune-mediated diseases
    • Mouthon, L. (1996) Mechanisms of action of intravenous immune globulin in immune-mediated diseases. Clin. exp. Immunol., 104(1), 3-9.
    • (1996) Clin. Exp. Immunol. , vol.104 , Issue.1 , pp. 3-9
    • Mouthon, L.1
  • 17
    • 0027948240 scopus 로고
    • Molecular chaperones in the processing and presentation of antigen to helper T cells
    • Pierce, S. K. (1994) Molecular chaperones in the processing and presentation of antigen to helper T cells. Experentia, 50, 1026-1030.
    • (1994) Experentia , vol.50 , pp. 1026-1030
    • Pierce, S.K.1
  • 18
    • 0029100960 scopus 로고
    • Presence of hsp65 in bacterial extracts (OM-89): A possible mediator of orally induced tolerance?
    • Polla, B. S., Baladi, S., Fuller, K. & Rook, G. (1995) Presence of hsp65 in bacterial extracts (OM-89): a possible mediator of orally induced tolerance? Experentia, 51, 775-779.
    • (1995) Experentia , vol.51 , pp. 775-779
    • Polla, B.S.1    Baladi, S.2    Fuller, K.3    Rook, G.4
  • 19
    • 0028798787 scopus 로고
    • Biological activity of bacterial cell wall components: Immunogenicity of the bacterial extract OM-89
    • Sedelmeier, E. A. & Bessler, W. G. (1995) Biological activity of bacterial cell wall components: immunogenicity of the bacterial extract OM-89. Immunopharm., 29, 29-36.
    • (1995) Immunopharm. , vol.29 , pp. 29-36
    • Sedelmeier, E.A.1    Bessler, W.G.2
  • 21
    • 0026346571 scopus 로고
    • OM-89: Its effect on T suppressor cell migration and on the develpoment of systemic lupus erythematosus
    • Twisk, A. J., Hoeban-Schornagel, K. & Kraal, G. (1991) OM-89: its effect on T suppressor cell migration and on the develpoment of systemic lupus erythematosus. Int. J. Immunother., 7, 181-187.
    • (1991) Int. J. Immunother. , vol.7 , pp. 181-187
    • Twisk, A.J.1    Hoeban-Schornagel, K.2    Kraal, G.3
  • 24
    • 0025342459 scopus 로고
    • Metabolic and functional stimulation of lymphocytes and macrophages by an Eschericia coli extract (OM-89); in vitro studies
    • Van Pham, T., Kreis, B., Corradin-Betz, S., Bauer, J. & Mauel, J. (1990) Metabolic and functional stimulation of lymphocytes and macrophages by an Eschericia coli extract (OM-89); in vitro studies. J. Biol. Respon. Modifiers, 9, 231-240.
    • (1990) J. Biol. Respon. Modifiers , vol.9 , pp. 231-240
    • Van Pham, T.1    Kreis, B.2    Corradin-Betz, S.3    Bauer, J.4    Mauel, J.5
  • 25
    • 0000121803 scopus 로고
    • Enzyme linked immunosorbent assay (ELISA)
    • (ed. Thompson, R. A.), Blackwell Scientific, Oxford
    • Voller, A. & De Savigny, D. (1981). Enzyme linked immunosorbent assay (ELISA). In Techniques in Clinical Immunology (ed. Thompson, R. A.), pp. 160-162. Blackwell Scientific, Oxford.
    • (1981) Techniques in Clinical Immunology , pp. 160-162
    • Voller, A.1    De Savigny, D.2
  • 26
    • 0029611709 scopus 로고
    • Polyarthritis in the rat; effects of tolerance and sensitisation to the bacterial extract OM-89 with a possible mode of action
    • Willis, D., Moore, A. R., Gowland, G. & Willoughby, D. A. (1995) Polyarthritis in the rat; effects of tolerance and sensitisation to the bacterial extract OM-89 with a possible mode of action. Br. J. Rheum., 34, 1135-1138.
    • (1995) Br. J. Rheum. , vol.34 , pp. 1135-1138
    • Willis, D.1    Moore, A.R.2    Gowland, G.3    Willoughby, D.A.4
  • 27
    • 0029085246 scopus 로고
    • OM-89 modulation of chronic inflammation: Relevance to clinical use
    • Willis, D., Moore, A. R., Gowland, G. & Willoughby, D. A. (1995) OM-89 modulation of chronic inflammation: relevance to clinical use. Br. J. Rheum., 34, 525-528.
    • (1995) Br. J. Rheum. , vol.34 , pp. 525-528
    • Willis, D.1    Moore, A.R.2    Gowland, G.3    Willoughby, D.A.4
  • 28
    • 0024437547 scopus 로고
    • Enhance ment of cytokine production and natural killer cell activity by an Eschericia coli extract
    • Wybran, J., Libin, M. & Schandene, L. (1989) Enhance ment of cytokine production and natural killer cell activity by an Eschericia coli extract. Onkologie, 3(12), 22-25.
    • (1989) Onkologie , vol.3 , Issue.12 , pp. 22-25
    • Wybran, J.1    Libin, M.2    Schandene, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.