메뉴 건너뛰기




Volumn 2, Issue 3, 1997, Pages 173-180

A randomized cross-over study comparing pharmacodynamic and metabolic variables of a new combiphasic and a well-established triphasic oral contraceptive

Author keywords

Combiphasic; Desogestrel; Levonorgestrel; Oral contraceptive; Pharmacodynamics; Triphasic

Indexed keywords

ANTITHROMBIN III; CARRIER PROTEIN; DESOGESTREL; ESTRADIOL; ESTRADIOL DERIVATIVE; ETHINYLESTRADIOL; ETHINYLESTRADIOL PLUS NORGESTREL; ORAL CONTRACEPTIVE AGENT; PROGESTERONE; PROGESTERONE DERIVATIVE;

EID: 0031217021     PISSN: 13625187     EISSN: None     Source Type: Journal    
DOI: 10.3109/13625189709167473     Document Type: Article
Times cited : (8)

References (48)
  • 1
    • 0025780913 scopus 로고
    • Multicentre study with a new biphasic oral contraceptive containing ethinylestradiol and desogestrel
    • Dieben TOM, van Beek A, Coelingh Bennink HJT. Multicentre study with a new biphasic oral contraceptive containing ethinylestradiol and desogestrel. Arzneimittelforschung 1991; 41: 996-8
    • (1991) Arzneimittelforschung , vol.41 , pp. 996-998
    • Dieben, T.O.M.1    Van Beek, A.2    Coelingh Bennink, H.J.T.3
  • 4
    • 0028067970 scopus 로고
    • The effects of CTR-24, a biphasic oral contraceptive combination, compared to Diane-35 in women with acne
    • Dieben TOM, Vromans L, Theeuwes A, Coelingh Bennink HJT. The effects of CTR-24, a biphasic oral contraceptive combination, compared to Diane-35 in women with acne. Contraception 1994; 50: 373-82
    • (1994) Contraception , vol.50 , pp. 373-382
    • Dieben, T.O.M.1    Vromans, L.2    Theeuwes, A.3    Coelingh Bennink, H.J.T.4
  • 5
    • 0026366233 scopus 로고
    • Acne treatment with a new estroprogestinic biphasic combination containing desogestrel
    • Falsetti L. Acne treatment with a new estroprogestinic biphasic combination containing desogestrel. Acta Eur Fertil 1991; 22: 283-6
    • (1991) Acta Eur Fertil , vol.22 , pp. 283-286
    • Falsetti, L.1
  • 6
    • 0028316454 scopus 로고
    • Efficacy on hyperandrogenism and safety of a new oral contraceptive biphasic formulation containing desogestrel
    • Volpe A, Silferi M, Mauri A, et al. Efficacy on hyperandrogenism and safety of a new oral contraceptive biphasic formulation containing desogestrel. Eur J Obstet Gynecol Reprod Biol 1994; 53: 205-9
    • (1994) Eur J Obstet Gynecol Reprod Biol , vol.53 , pp. 205-209
    • Volpe, A.1    Silferi, M.2    Mauri, A.3
  • 7
    • 0019506253 scopus 로고
    • Antithrombin III: Referenzwerte mit einem chromogenen Substrat (Cromozym TH)
    • Hesse R, Tritschler W, Castelfranchi G, Bablok W. Antithrombin III: Referenzwerte mit einem chromogenen Substrat (Cromozym TH). Blut 1981; 42: 227-34
    • (1981) Blut , vol.42 , pp. 227-234
    • Hesse, R.1    Tritschler, W.2    Castelfranchi, G.3    Bablok, W.4
  • 8
    • 34250919144 scopus 로고
    • Enzymatische Bestimmung der Glucose in Blut, Liquor und Harn
    • Barthelmai W, Czok R. Enzymatische Bestimmung der Glucose in Blut, Liquor und Harn. Klin Wochenschr 1962; 40: 585-9
    • (1962) Klin Wochenschr , vol.40 , pp. 585-589
    • Barthelmai, W.1    Czok, R.2
  • 9
    • 0015376786 scopus 로고
    • Determination of total serum insulin (IRI) in insulin-treated diabetic patients
    • Heding LG. Determination of total serum insulin (IRI) in insulin-treated diabetic patients. Diabetologia 1972; 8: 260-6
    • (1972) Diabetologia , vol.8 , pp. 260-266
    • Heding, L.G.1
  • 10
    • 1842733360 scopus 로고
    • Serum glycosylated proteins as a measure of carbohydrate metabolism in OC users
    • Harrison R, Bonnar J, Thompson W, eds. Lancaster: MTP Press
    • Kloosterboer HJ, Bruining GJ, Lund L, et al. Serum glycosylated proteins as a measure of carbohydrate metabolism in OC users. In Harrison R, Bonnar J, Thompson W, eds. Trends in Oral Contraception. Lancaster: MTP Press, 1983; 9-15
    • (1983) Trends in Oral Contraception , pp. 9-15
    • Kloosterboer, H.J.1    Bruining, G.J.2    Lund, L.3
  • 11
    • 0016331976 scopus 로고
    • Measurement of ceruloplasmin from its oxidase activity in serum by use of O-dianisidine dihydrochloride
    • Schosinski KH, Lehman HP, Beller MF. Measurement of ceruloplasmin from its oxidase activity in serum by use of O-dianisidine dihydrochloride. Clin Chem 1974; 20: 1556-63
    • (1974) Clin Chem , vol.20 , pp. 1556-1563
    • Schosinski, K.H.1    Lehman, H.P.2    Beller, M.F.3
  • 12
    • 0017295079 scopus 로고
    • A filter assay for the corticosteroid binding globulin of human serum
    • Schiller HS, Petra PH. A filter assay for the corticosteroid binding globulin of human serum. J Steroid Biochem 1976; 7: 55-9
    • (1976) J Steroid Biochem , vol.7 , pp. 55-59
    • Schiller, H.S.1    Petra, P.H.2
  • 13
    • 0019801474 scopus 로고
    • Effects of oral contraceptive combinations containing levonorgestrel or desogestrel on serum proteins and androgen binding
    • Bergink EW, Holma P, Pyörälä T. Effects of oral contraceptive combinations containing levonorgestrel or desogestrel on serum proteins and androgen binding. Scand J Clin Lab Invest 1981; 41: 663-8
    • (1981) Scand J Clin Lab Invest , vol.41 , pp. 663-668
    • Bergink, E.W.1    Holma, P.2    Pyörälä, T.3
  • 14
    • 84964162953 scopus 로고
    • Simple turbidimetric method for the determination of serum cholesterol
    • Trinder P. Simple turbidimetric method for the determination of serum cholesterol. Ann Clin Biochem 1969; 6 165-6
    • (1969) Ann Clin Biochem , vol.6 , pp. 165-166
    • Trinder, P.1
  • 15
    • 0013886273 scopus 로고
    • Eine neue Bestimmung der Neutralfette im Blutserum und Gewebe
    • Eggstein H, Kreutz FH. Eine neue Bestimmung der Neutralfette im Blutserum und Gewebe. Klin Wochenschr 1966; 44: 262-7
    • (1966) Klin Wochenschr , vol.44 , pp. 262-267
    • Eggstein, H.1    Kreutz, F.H.2
  • 16
    • 0017656417 scopus 로고
    • A new enzymatic method for determination of serum choline-containing phospholipids
    • Takayama M, Itoh S, Nagasaki T, Tamimizu I. A new enzymatic method for determination of serum choline-containing phospholipids. Clin Chem Acta 1977; 79: 93-8
    • (1977) Clin Chem Acta , vol.79 , pp. 93-98
    • Takayama, M.1    Itoh, S.2    Nagasaki, T.3    Tamimizu, I.4
  • 17
    • 0019508807 scopus 로고
    • Improved techniques for the separation of serum lipoproteins by density gradient ultracentrifugation: Visualization by prestaining and rapid separation of serum lipoproteins from small volumes of serum
    • Terpstra AHM, Woodward CJH, Sanchez-Muniz FJ. Improved techniques for the separation of serum lipoproteins by density gradient ultracentrifugation: visualization by prestaining and rapid separation of serum lipoproteins from small volumes of serum. Anal Biochem 1981; 111: 149-57
    • (1981) Anal Biochem , vol.111 , pp. 149-157
    • Terpstra, A.H.M.1    Woodward, C.J.H.2    Sanchez-Muniz, F.J.3
  • 18
    • 0014876627 scopus 로고
    • Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions
    • Burstein M, Scholnick HR, Morfin R. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J Lipid Res 1978; 11: 583-95
    • (1978) J Lipid Res , vol.11 , pp. 583-595
    • Burstein, M.1    Scholnick, H.R.2    Morfin, R.3
  • 19
    • 0017350190 scopus 로고
    • Cholesterol determination in high-density lipoproteins separated by three methods
    • Lopes-Virella MF, Stone P, Ellis S, Colwell JA. Cholesterol determination in high-density lipoproteins separated by three methods. Clin Chem 1977; 23: 882-4
    • (1977) Clin Chem , vol.23 , pp. 882-884
    • Lopes-Virella, M.F.1    Stone, P.2    Ellis, S.3    Colwell, J.A.4
  • 20
    • 0013895324 scopus 로고
    • Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies
    • Laurell CB. Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Anal Biochem 1966; 15: 45-52
    • (1966) Anal Biochem , vol.15 , pp. 45-52
    • Laurell, C.B.1
  • 21
    • 0018398041 scopus 로고
    • The two-period cross-over clinical trial
    • Hills M, Armitage P. The two-period cross-over clinical trial. Br J Clin Pharmacol 1979; 8: 7-20
    • (1979) Br J Clin Pharmacol , vol.8 , pp. 7-20
    • Hills, M.1    Armitage, P.2
  • 22
    • 0023141562 scopus 로고
    • The forgotten pill - and the paramount importance of the pill-free week
    • Guillebaud J. The forgotten pill - and the paramount importance of the pill-free week. Br J Fam Plann 1987; 12(Suppl 4): 35-43
    • (1987) Br J Fam Plann , vol.12 , Issue.4 SUPPL. , pp. 35-43
    • Guillebaud, J.1
  • 23
    • 0027518467 scopus 로고
    • The effect of a biphasic desogestrel-containing oral contraceptive on carbohydrate metabolism and various hormonal parameters
    • Kuhl H, Jung-Hoffmann C, Weber J, Boehm BO. The effect of a biphasic desogestrel-containing oral contraceptive on carbohydrate metabolism and various hormonal parameters. Contraception 1993; 47: 55-68
    • (1993) Contraception , vol.47 , pp. 55-68
    • Kuhl, H.1    Jung-Hoffmann, C.2    Weber, J.3    Boehm, B.O.4
  • 24
    • 0015405115 scopus 로고
    • The effect of estrogens on carbohydrate metabolism: Glucose, insulin, and growth hormone studies in one hundred and seventy women ingesting Premarin, mestranol, and ethinyl estradiol for six months
    • Spellacy WN, Buhi WC, Birk SA. The effect of estrogens on carbohydrate metabolism: glucose, insulin, and growth hormone studies in one hundred and seventy women ingesting Premarin, mestranol, and ethinyl estradiol for six months. Am J Obstet Gynecol 1972; 114: 378-92
    • (1972) Am J Obstet Gynecol , vol.114 , pp. 378-392
    • Spellacy, W.N.1    Buhi, W.C.2    Birk, S.A.3
  • 25
    • 0019997196 scopus 로고
    • The effects of two years of mestranol treatment on carbohydrate metabolism
    • Spellacy WN, Buhi WC, Birk SA. The effects of two years of mestranol treatment on carbohydrate metabolism. Metabolism 1982; 31: 1006-8
    • (1982) Metabolism , vol.31 , pp. 1006-1008
    • Spellacy, W.N.1    Buhi, W.C.2    Birk, S.A.3
  • 26
    • 0026579457 scopus 로고
    • Insulin resistance, secretion, and metabolism in users of oral contraceptives
    • Godsland IF, Walton C, Felton C, et al. Insulin resistance, secretion, and metabolism in users of oral contraceptives. J Clin Endocrinol Metab 1991; 74: 64-70
    • (1991) J Clin Endocrinol Metab , vol.74 , pp. 64-70
    • Godsland, I.F.1    Walton, C.2    Felton, C.3
  • 27
    • 0025082495 scopus 로고
    • Clinical aspects of the relationship between oral contraceptives, abnormalities in carbohydrate metabolism, and the development of cardiovascular disease
    • Gaspard U, Lefebre PJ. Clinical aspects of the relationship between oral contraceptives, abnormalities in carbohydrate metabolism, and the development of cardiovascular disease. Am J Obstet Gynecol 1990; 163: 334-43
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 334-343
    • Gaspard, U.1    Lefebre, P.J.2
  • 28
    • 0019502458 scopus 로고
    • Human corticosteroid binding globulin
    • Brien TG. Human corticosteroid binding globulin. Clin Endocrinol 1981; 14: 193-212
    • (1981) Clin Endocrinol , vol.14 , pp. 193-212
    • Brien, T.G.1
  • 29
    • 0014387214 scopus 로고
    • Investigations on the effects of an oral contraceptive and its components on liver function, serum proteins, copper, ceruloplasmin and gamma-glutamyl peptidase in postmenopausal women
    • Adlercreutz H, Eisalo A, Heino A, et al. Investigations on the effects of an oral contraceptive and its components on liver function, serum proteins, copper, ceruloplasmin and gamma-glutamyl peptidase in postmenopausal women. Scand J Gastroenterol 1968; 3: 273-84
    • (1968) Scand J Gastroenterol , vol.3 , pp. 273-284
    • Adlercreutz, H.1    Eisalo, A.2    Heino, A.3
  • 30
    • 0026987502 scopus 로고
    • Serum concentrations of ethinylestradiol, 3-keto-desogestrel, SHBG, CBG and gonadotropins during treatment with a biphasic oral contraceptive containing desogestrel
    • Jung-Hoffmann C, Storch A, Kuhl H. Serum concentrations of ethinylestradiol, 3-keto-desogestrel, SHBG, CBG and gonadotropins during treatment with a biphasic oral contraceptive containing desogestrel. Horm Res 1992; 38: 184-9
    • (1992) Horm Res , vol.38 , pp. 184-189
    • Jung-Hoffmann, C.1    Storch, A.2    Kuhl, H.3
  • 31
    • 0019940475 scopus 로고
    • On the use of plasma proteins as indicators of the metabolic effects of combined oral contraceptives
    • Cullberg G, Dovré PA, Lindstedt G, Steffensen K. On the use of plasma proteins as indicators of the metabolic effects of combined oral contraceptives. Acta Obstet Gynecol Scand 1982; (Suppl 111): 47-54
    • (1982) Acta Obstet Gynecol Scand , Issue.111 SUPPL. , pp. 47-54
    • Cullberg, G.1    Dovré, P.A.2    Lindstedt, G.3    Steffensen, K.4
  • 32
    • 0023848910 scopus 로고
    • Progestagen-dependent effect on some plasma proteins during oral contraception
    • Liukko P, Erkkola R, Bergink EW. Progestagen-dependent effect on some plasma proteins during oral contraception. Gynecol Obstet Invest 1988; 25: 118-22
    • (1988) Gynecol Obstet Invest , vol.25 , pp. 118-122
    • Liukko, P.1    Erkkola, R.2    Bergink, E.W.3
  • 33
    • 84907038143 scopus 로고
    • Androgen transport proteins: Physical properties, hormonal regulation, and possible mechanism of TeBG and ABP action
    • Lobl TJ. Androgen transport proteins: physical properties, hormonal regulation, and possible mechanism of TeBG and ABP action. Arch Androl 1981; 7: 133-51
    • (1981) Arch Androl , vol.7 , pp. 133-151
    • Lobl, T.J.1
  • 34
    • 0023802958 scopus 로고
    • Selectivity in progesterone- and androgen-receptor binding of progestogens used in oral contraceptives
    • Kloosterboer HJ, Vonk Noordegraaf CA, Turpijn EW. Selectivity in progesterone- and androgen-receptor binding of progestogens used in oral contraceptives. Contraception 1988; 38: 325-32
    • (1988) Contraception , vol.38 , pp. 325-332
    • Kloosterboer, H.J.1    Vonk Noordegraaf, C.A.2    Turpijn, E.W.3
  • 35
    • 0020040466 scopus 로고
    • Oral contraception and blood coagulation: A critical review
    • Mammen EF. Oral contraception and blood coagulation: a critical review. Am J Obstet Gynecol 1982; 142: 781-90
    • (1982) Am J Obstet Gynecol , vol.142 , pp. 781-790
    • Mammen, E.F.1
  • 36
    • 0027497664 scopus 로고
    • Effect on lipid metabolism of a biphasic desogestrel-containing oral contraceptive: Divergent changes in apolipoprotein B and e and transitory decrease in Lp(a) levels
    • Kuhl H, März W, Jung-Hoffmann C, et al. Effect on lipid metabolism of a biphasic desogestrel-containing oral contraceptive: divergent changes in apolipoprotein B and E and transitory decrease in Lp(a) levels. Contraception 1993; 47: 69-83
    • (1993) Contraception , vol.47 , pp. 69-83
    • Kuhl, H.1    März, W.2    Jung-Hoffmann, C.3
  • 37
    • 0025014653 scopus 로고
    • High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: The follow-up study of the Lipid Research Clinics Prevalence Study
    • Jacobs DR, Mebane IL, Bangdiwala SI, et al. High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: the follow-up study of the Lipid Research Clinics Prevalence Study. Am J Epidemiol 1990; 131: 32-47
    • (1990) Am J Epidemiol , vol.131 , pp. 32-47
    • Jacobs, D.R.1    Mebane, I.L.2    Bangdiwala, S.I.3
  • 38
    • 0023189234 scopus 로고
    • Metabolic risk factors for coronary heart disease in women: Perspective from the Framingham Study
    • Kannel WB. Metabolic risk factors for coronary heart disease in women: perspective from the Framingham Study. Am Heart J 1987; 114: 413-19
    • (1987) Am Heart J , vol.114 , pp. 413-419
    • Kannel, W.B.1
  • 39
    • 0024551344 scopus 로고
    • Multivariate analysis of the twenty-year follow-up of the Donol-Tel Aviv Prospective Coronary Artery Disease Study and the usefulness of high density lipoprotein cholesterol percentage
    • Livshits G, Weisbort J, Meshulam N, Brunner D. Multivariate analysis of the twenty-year follow-up of the Donol-Tel Aviv Prospective Coronary Artery Disease Study and the usefulness of high density lipoprotein cholesterol percentage. Am J Cardiol 1989; 63: 676-81
    • (1989) Am J Cardiol , vol.63 , pp. 676-681
    • Livshits, G.1    Weisbort, J.2    Meshulam, N.3    Brunner, D.4
  • 40
    • 0023726344 scopus 로고
    • Lipoprotein alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study
    • Manninen V, Elo MO, Frick MH, et al. Lipoprotein alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study. J Am Med Assoc 1988; 260: 641-51
    • (1988) J Am Med Assoc , vol.260 , pp. 641-651
    • Manninen, V.1    Elo, M.O.2    Frick, M.H.3
  • 41
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • Brown G, Albers JJ, Fisher LD, et al. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N Engl J Med 1990; 323: 1289-98
    • (1990) N Engl J Med , vol.323 , pp. 1289-1298
    • Brown, G.1    Albers, J.J.2    Fisher, L.D.3
  • 42
    • 84948007950 scopus 로고
    • Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts
    • Blankenhorn DH, Johnson RL, Nessim SA, et al. Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts. J Am Med Assoc 1987; 257: 3233-40
    • (1987) J Am Med Assoc , vol.257 , pp. 3233-3240
    • Blankenhorn, D.H.1    Johnson, R.L.2    Nessim, S.A.3
  • 43
    • 0022485574 scopus 로고
    • The triglyceride issue: A view from Framingham
    • Castelli WP. The triglyceride issue: a view from Framingham. Am Heart J 1986; 112: 432-7
    • (1986) Am Heart J , vol.112 , pp. 432-437
    • Castelli, W.P.1
  • 44
    • 0027506828 scopus 로고
    • Triglyceride, high-density lipoprotein, and coronary heart disease
    • NIH Consensus Development Panel on Triglyceride, High-Density Lipoprotein, and Coronary Heart Disease. Triglyceride, high-density lipoprotein, and coronary heart disease. J Am Med Assoc 1993; 269: 505-10
    • (1993) J Am Med Assoc , vol.269 , pp. 505-510
  • 45
    • 0023265766 scopus 로고
    • Cardiovascular mortality and non-contraceptive estrogen use in women: Results from the Lipid Research Clinics' Program Follow-Up Study
    • Bush TL, Barrett-Connor E, Cowan LD, et al. Cardiovascular mortality and non-contraceptive estrogen use in women: results from the Lipid Research Clinics' Program Follow-Up Study. Circulation 1987; 75: 1002-9
    • (1987) Circulation , vol.75 , pp. 1002-1009
    • Bush, T.L.1    Barrett-Connor, E.2    Cowan, L.D.3
  • 46
    • 0029671040 scopus 로고    scopus 로고
    • Lewis MA, Spitzer WO, Heinemann LA, et al. on behalf of the Transnational Research Group on Oral Contraceptives and the Health of Young Women. Br Med J 1996; 312: 88-90
    • (1996) Br Med J , vol.312 , pp. 88-90
    • Lewis, M.A.1    Spitzer, W.O.2    Heinemann, L.A.3
  • 47
    • 0030025822 scopus 로고    scopus 로고
    • Risk of acute myocardial infarction and low-dose combined oral contraceptives
    • Jick H, Jick SS, Wald Myers M, Vasilakis C. Risk of acute myocardial infarction and low-dose combined oral contraceptives. Lancet 1996; 347: 627-8
    • (1996) Lancet , vol.347 , pp. 627-628
    • Jick, H.1    Jick, S.S.2    Wald Myers, M.3    Vasilakis, C.4
  • 48
    • 0025372083 scopus 로고
    • Metabolic aspects of oral contraceptives of relevance for cardiovascular diseases
    • Consensus Development meeting. Metabolic aspects of oral contraceptives of relevance for cardiovascular diseases. Am J Obstet Gynecol 1990; 162: 1335-7
    • (1990) Am J Obstet Gynecol , vol.162 , pp. 1335-1337


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.