The transition from proliferation to differentiation in nerve cells: What can we learn from muscle?

Experimental Cell Research

Volumn 234, Issue 2, 1997, Pages 193-204

  Piette, Jacques ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; GENE EXPRESSION REGULATION; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0031214922     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1997.3588     Document Type: Article

References (117)

1. 1. Akazawa, C., Sasai, Y., Nakanishi, S., and Kageyama, R. (1992) Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system. J. Biol. Chem. 267, 21879-21885.
2. 2. Andrés, V., and Walsh, K. (1996) Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis. J. Cell Biol. 132, 657-666.
3. 12 myoblasts by the Id3 helix-loop-helix protein. Cell Growth Differ. 7, 1059-1066.
4. 4. Bartek, J., Bartkova, J., and Lukas, J. (1996) The retinoblastoma protein pathway and the restriction point. Curr. Opin. Cell Biol. 8, 805-814.
5. 5. Bates, S., and Vousden, K. H. (1996) p53 in signaling checkpoint arrest or apoptosis. Curr. Opin. Genet. Dev. 6, 12-19.
6. 6. Benezra, R., Davis, R. L., Lockson, D., Turner, D. L., and Weintraub, H. (1990) The protein Id: A negative regulator of helix-loop-helix DNA binding proteins. Cell 61, 49-59.
7. 7. Bengal, E., Ransone, L., Scharfmann, R., Dwarki, V. J., Tapscott, S. J., Weintraub, H., and Verma, I. M. (1992) Functional antagonism between c-Jun and MyoD proteins: A direct physical association. Cell 68, 507-519.
8. 8. Biggs, J., Murphy, E. V., and Israel, M. A. (1992) A human Id-like helix-loop-helix protein expressed during early development. Proc. Natl. Acad. Sci. USA 89, 1512-1516.
9. WAF1/CIP1 is induced through a p300-dependent mechanism during NGF-mediated neuronal differentiation of PC12 cells. Oncogene 13, 2047-2054.
10. 10. Bischoff, R., and Holtzer, H. (1969) Mitosis and the processes of differentiation in myogenic cells in vitro. J. Cell Biol. 41, 188-200.
11. 11. Blaschke, A. J., Staley, K., and Chun, J. (1996) Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex. Development 122, 1165-1174.
12. 12. Boulukos, K. E., and Ziff, E. B. (1993) Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism. Oncogene 8, 237-248.
13. 13. Brugarolas, J., Chandrasekaran, C., Gordon, J. I., Beach, D., Jacks, T., and Hannon, G. J. (1995) Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377, 552-557.
14. cdc2 kinases in PC12 pheochromocytoma cells. Mol. Biol. Cell 5, 1225-1241.
15. 15. Caruso, M., Martelli, F., Giordano, A., and Felsani, A. (1993) Regulation of MyoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein. Oncogene 8, 267-278.
16. 16. Caviness, V. S., Jr., Takahashi, T., and Nowakowski, R. S. (1995) Numbers, time and neocortical neurogenesis: A general developmental and evolutionary model. Trends Neurosci. 18, 379-383.
17. 17. Chitnis, A., and Kintner, C. (1996) Sensitivity of proneural genes to lateral inhibition affects the pattern of primary neurons in Xenopus embryos. Development 122, 2295-2301.
18. 18. Christy, B. A., Sanders, L. K., Lau, L. F., Copeland, N. G., Jenkins, N. A., and Nathans, D. (1991) An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene. Proc. Natl. Acad. Sci. USA 88, 1815-1819.
19. 19. Cobrinik, D., Lee, M.-H., Hannon, G., Mulligan, G., Bronson, R. T., Dyson, N., Harlow, E., Beach, D., Weinberg, D., and Jacks, T. (1996) Shared role of the pRb-related p130 and p107 proteins in limb development. Genes Dev. 10, 1633-1644.
20. 20. Corbeil, H. B., Whyte, P., and Branton, P. E. (1995) Characterization of transcription factor E2F complexes during muscle and neuronal differentiation. Oncogene 11, 909-920.
21. 21. Davis, R. L., Weintraub, H., and Lassar, A. B. (1987) Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51, 987-1000.
22. CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82, 675-684.
23. 23. Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Butel, J. S., and Bradley, A. (1992) Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356, 215-221.
24. 24. Dorée, M., and Galas, S. (1994) The cyclin-dependent protein kinases and the control of cell division. FASEB J. 8, 1114-1121.
25. 25. Duncan, M., DiCicco-Bloom, E. M., Xiang, X., Benezra, R., and Chada, K. (1992) The gene for the helix-loop-helix protein, Id, is specifically expressed in neural precursors. Dev. Biol. 154, 1-10.
26. 26. Eckner, R., Yao, T.-P., Oldread, E., and Livingston, D. M. (1996) Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev. 10, 2478-2490.
27. 27. Edgar, B. (1995) Diversification of cell cycle controls in developing embryos. Curr. Opin. Cell Biol. 7, 815-824.
28. 28. Einarson, M. B., and Chao, M. V. (1995) Regulation of Id1 and its association with basic helix-loop-helix proteins during nerve growth factor-induced differentiation of PC12 cells. Mol. Cell. Biol. 15, 4175-4183.
29. 29. Eizenberg, O., Faber-Elman, A., Gottlieb, E., Oren, M., Rotter, V., and Schwartz, M. (1996) p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells. Mol. Cell. Biol. 16, 5178-5185.
30. 30. Endo, T., and Nadal-Ginard, B. (1989) in SV40 Large T Antigen Induces Re-entry of Terminally Differentiated Myotubes into the Cell Cycle (Kedes, L. H., and Stockdale, F., Eds.), pp. 95-104, Liss, New York.
31. 31. Feder, J. N., Jan, L. Y., and Jan, Y. N. (1993) A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation. Mol. Cell. Biol. 13, 105-113.
32. 32. Ferreira, A., and Kosik, K. S. (1996) Accelerated neuronal differentiation induced by p53 suppression. J. Cell Sci. 109, 1509-1516.
33. 33. Ferreiro, B., Skoglund, P., Bailey, A., Dorsky, R., and Harris, W. A. (1993) XASH1, a Xenopus homolog of achaete-scute: A proneural gene in anterior regions of the vertebrate CNS. Mech. Dev. 40, 25-36.
34. 34. Galaktionov, K., Chen, X., and Beach, D. (1996) Cdc25 cell-cycle phosphatase as a target of c-myc. Nature 382, 511.
35. 35. Greene, L. A., and Tischler, A. S. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.
36. 36. Gu, W., Schneider, J. W., Condorelli, G., Kaushal, S., Mahdavi, V., and Nadal-Ginard, B. (1993) Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72, 309-324.
37. 37. Guillemot, F., Lo, L.-C., Johnson, J. E., Auerbach, A., Anderson, D. J., and Joyner, A. L. (1993) Mammalian achaete-scute homologue 1 is required for the early development of olfactory and autonomic neurons. Cell 75, 463.
38. 38. Guo, K., Wang, J., Andres, V., Smith, R. C., and Walsh, K. (1995) MyoD-induced expression pf p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol. Cell. Biol. 15, 3823-3829.
39. 39. Halevy, O., Novitch, B. G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., Beach, D., and Lassar, A. B. (1995) Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 267, 1018-1021.
40. 40. Hebrock, M., Wertz, K., and Fuchtbauer, E. M. (1994) M-Twist is an inhibitor of muscle differentiation. Dev. Biol. 165, 537-544.
41. 41. Hoshimura, M., Ray, J., Sah, D. W. Y., and Gage, F. H. (1996) Differentiation of the immortalized adult neuronal cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene. Proc. Natl. Acad. Sci. USA 93, 1518-1523.
42. 42. Iavarone, A., Garg, P., Lasorella, A., Hsu, J., and Israel, M. A. (1994) The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein. Genes Dev. 8, 1270-1284.
43. 43. Ishibashi, M., Ang, S. L., Shiota, K., Nakanishi, S., Kageyama, R., and Guillemot, F. (1995) Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev. 9, 3136-3148.
44. 44. Iujvidin, S., Fuchs, O., Nudel, U., and Yaffe, D. (1990) SV40 immortalizes myogenic cells: DNA synthesis and mitosis in differentiated myotubes. Differentiation 43, 192-203.
45. 45. Jacks, T., Fazeli, A., Schmitt, E. M., Bronson, R. T., Goodell, M. A., and Weinberg, R. (1992) Effects of an Rb mutation in the mouse. Nature 359, 295-300.
46. 46. Jacobson, M. (1991) Developmental Neurobiology, Plenum, New York/London.
47. 47. Johnson, J. E., Birren, S. J., and Anderson, D. J. (1990) Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors. Nature 346, 858-861.
48. 48. Johnson, J. E., Zimmerman, K., Saito, T., and Anderson, D. J. (1992) Induction and repression of mammalian achaete-scute homologue (MASH) gene expression during neuronal differentiation of P19 embryonal carcinoma cells. Development 114, 75-87.
49. 49. Kageyama, R., Sasai, C., Akazawa, C., Ishibashi, M., Takebayashi, K., Shimizu, C., Tomita, K., and Nakanishi, S. (1995) Regulation of mammalian neural development by helix-loop-helix transcription factors. Crit. Rev. Neurobiol. 9, 177-188.
50. 6 myoblast differentiation. Cell Growth Differ. 6, 1287-1298.
51. 51. Kopan, R., Nye, J. S., and Weintraub, H. (1994) The intracellular domain of mouse notch-a constitutively activated represser of myogenesis directed at the basic helix-loop-helix region of MyoD. Development 120, 2385-2396.
52. 52. Kranenburg, O., Scharnhorst, V., Van der Eb, A. J., and Zantema, A. (1995) Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells. J. Cell Biol. 131, 227-234.
53. 53. Lapham, L. W. (1967) Tetraploid DNA content of Purkinje neurons of human cerebellar cortex. Science 159, 310-312.
54. 54. Lardelli, M., Williams, R., and Lendahl, U. (1995) Notch-related genes in animal development. Int. J. Dev. Biol. 39, 769-780.
55. 55. Lassar, A., and Münsterberg, A. (1994) Wiring diagrams: Regulatory circuits and the control of skeletal myogenesis. Curr. Opin. Cell Biol. 6, 432-442.
56. 56. Lee, E. Y.-H., Chang, C.-Y., Hu, N., Wang, Y.-C., Lai, C.-C., Herrup, K., Lee, W.-H., and Bradley, A. (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359, 288-294.
57. 57. Lee, E. Y.-H. P., Hu, N., Yuan, S.-S. F., Cox, L. A., Bradley, A., Lee, W.-H., and Herrup, K. (1994) Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 8, 2008-2021.
58. 58. Lee, J. E., Hollenberg, S. M., Snider, L., Turner, D. L., Lipnick, N., and Weintraub, H. (1995) Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 168, 836-844.
59. Kip1 in neurons. Proc. Natl. Acad. Sci. USA 93, 3259-3263.
60. 60. Lee, M.-H., Williams, B. O., Mulligan, G., Mukai, S., Bronson, R. T., Dyson, N., Harlow, E., and Jacks, T. (1996) Targeted disruption of p 107: Functional overlap between p107 and Rb. Genes Dev. 10, 1621-1632.
61. 61. Levine, A. J. (1993) Annu. Rev. Biochem. 62, 623-651.
62. 62. Lew, D. J., and Kornbluth, S. (1996) Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. Curr. Opin. Cell Biol. 8, 795-804.
63. 63. Li, L., Zhou, J., James, G., Heller-Harrison, R., Czech, M. P., and Olson, E. N. (1992) FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains. Cell 71, 1181-1194.
64. 64. Lindsell, C. E., Shawber, C. J., Boulter, J., and Weinmaster, G. (1995) Jagged - A mammalian ligand that activates notch 1. Cell 80, 909-917.
65. 65. Lois, A. F., Cooper, L. T., Geng, Y., Nobori, T., and Carson, D. (1995) Expression of the p16 and p15 cyclin-dependent kinase inhibitors in lymphocyte activation and neuronal differentiation. Cancer Res. 55, 4010-4013.
66. 66. LoPresti, P., Poluha, W., Poluha, D. K., Drinkwater, E., and Ross, A. H. (1992) Neuronal differentiation triggered by blocking cell proliferation. Cell Growth Differ. 3, 627-635.
67. 67. Ma, Q., Kintner, C., and Anderson, D. J. (1996) Cell 87, 43.
68. 68. Macleod, K. F., Hu, Y., and Jacks, T. (1996) Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J. 15, 6178-6188.
69. 69. Maruyama, K., Schiavi, S. C., Huse, W., Johnson, G. L., and Ruley, H. E. (1987) myc and E1A oncogenes alter the responses of PC12 cells to nerve growth factor and block differentiation. Oncogene 1, 361-367.
70. 70. McConnell, S. K. (1995) Constructing the cerebral cortex: Neurogenesis and fate determination. Neuron 15, 761-768.
71. 71. Melnikova, I. N., and Christy, B. A. (1996) Muscle cell differentiation is inhibited by the helix-loop-helix protein Id3. Cell Growth Differ. 7, 1067-1079.
72. 72. Molkentin, J. D., and Olson, E. N. (1996) Defining the regulatory networks for muscle development. Curr. Opin. Genet. Dev. 6, 445-453.
73. 73. Morgan, D. O. (1996) The dynamics of cyclin dependent kinase structure. Curr. Opin. Cell Biol. 8, 767-772.
74. 74. Mymryk, J. S., Lee, R. W. H., and Bayley, S. T. (1992) Mol. Biol. Cell 3, 1107-1115.
75. 75. Nadal-Ginard, B. (1978) Commitment, fusion and biochemical differentiation of a myogenic cell line in the absence of DNA synthesis. Cell 15, 855-864.
76. Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85, 707-720.
77. 77. Neuman, T., Keen, A., Zuber, M. X., Kristjansson, G. I., Gruss, P., and Nornes, H. O. (1993) Neuronal expression of regulatory helix-loop-helix factor Id2 gene in mouse. Dev. Biol. 160, 185-195.
78. 78. Nevins, J. R. (1992) E2F: A link between the Rb tumor suppressor protein and viral oncoproteins. Science 258, 424-429.
79. 2 phases of the cell cycle. J. Cell Biol. 135, 441-456.
80. 80. Ogryzko, V. V., Schlitz, R. L., Russanova, V., Howard, B. H., and Nakatani, Y. (1996) The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87, 953-959.
81. 81. Olson, E. N. (1992) Interplay between proliferation and differentiation within the myogenic lineage. Dev. Biol. 154, 261-272.
82. 82. Olson, E. N., Sternberg, W., Hu, J. S., Spizz, G., and Wilcox, C. (1986) Regulation of myogenic differentiation by type b transforming growth factor. J. Cell Biol. 103, 1799-1805.
83. 83. Parker, S. B., Eichele, G., Zhang, P., Rawls, A., Sands, A. T., Bradley, A., Olson, E. N., Harper, J. W., and Elledge, S. J. (1995) p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267, 1024-1027.
84. 84. Peverali, F. A., Orioli, D., Tonon, L., Ciana, P., Bunone, G., Negri, M., and Della-Valle, G. (1996) Retinoic acid-induced growth arrest and differentiation of neuroblastoma cells are counteracted by N-myc and enhanced by max overexpression. Oncogene 12, 457-462.
85. WAF1 is required for survival of differentiating neuroblastoma cells. Mol. Cell. Biol. 16, 1335-1341.
86. 86. Polyak, K., Waldmann, T., He, T.-C., Kinzler, K. W., and Vogelstein, B. (1996) Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev. 10, 1945-1952.
87. 87. Rao, S. S., Chu, C., and Kohtz, D. S. (1994) Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators. Mol. Cell. Biol. 14, 5259-5267.
88. 88. Rao, S. S., and Kohtz, D. S. (1995) Positive and negative regulation of D-type cyclin expression in skeletal myoblasts y basic fibroblast factor beta. A role for cyclin D1 in control of myoblast differentiation. J. Biol. Chem. 270, 4093-4100.
89. 89. Riechmann, V., van Cruchten, I., and Sablitzki, F. (1994) The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. Nucleic Acids Res. 22, 749-755.
90. 90. Rudkin, B. B., Lazarovici, P., Levi, B.-Z., Abe, Y., Fujita, K., and Guroff, G. (1989) EMBO J. 8, 3319-3325.
91. 91. Sah, V. P., Attardi, L. D., Mulligan, G. J., Williams, B. O., Bronson, R. T., and Jacks, T. (1995) A subset of p53-deficient embryos exhibit exencephaly. Nature Genet. 10, 175-179.
92. 92. Sardet, C., LeCam, L., Fabbrizio, E., and Vidal, M. (in press) in E2Fs and the Retinoblastoma Protein Family (Karin, M., and Yaniv, M., Eds.), Birkhaüser, Basel.
93. 93. Sasai, Y., Kageyama, R., Tagawa, Y., Shigemoto, R., and Nakanishi, S. (1992) Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev. 6, 2620-2634.
94. 94. Schneider, J. W., Gu, W., Zhu, L., Mahdavi, V., and NadalGinard, B. (1994) Reversal of terminal differentiation mediated by p107 in Rb -/-muscle cells. Science 264, 1467-1471.
95. 95. Sherr, C. J. (1994) G1 phase progression: Cycling on cue. Cell 79, 551-555.
96. 96. Sherr, C. J., and Roberts, J. M. (1995) Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9, 1149-1163.
97. 97. Shin, E. K., Shin, A., Paulding, C., Schaffhausen, B., and Yee, A. S. (1995) Multiple changes in E2F function and regulation occur upon muscle differentiation. Mol. Cell. Biol. 15, 2252-2262.
98. 98. Skapek, S. X., Rhee, J., Kim, P. S., Novitch, B. G., and Lassar, A. B. (1996) Cyclin-mediated inhibition of muscle gene expression via a mechanism that is independent of pRb hyperphosphorylation. Mol. Cell. Biol. 16, 7043-7053.
99. 99. Skapek, S. X., Rhee, J., Spicer, D. B., and Lassar, A. B. (1995) Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase. Science 267, 1022-1024.
100. 100. Soddu, S., Blandino, G., Scardigli, R., Coen, S., Marcchetti, A., Rizzo, M. G., Bossi, G., Cimino, L., Crescenzi, M., and Sacchi, A. (1996) Interference with p53 protein inhibits hematopoietic and muscle differentiation. J. Cell Biol. 134, 193-204.
101. 101. Sorrentino, V., Pepperkok, R., Davis, R. L., Ansorge, W., and Phillipson, L. (1990) Cell proliferation inhibited by MyoD independently of myogenic differentiation. Nature 345, 813-815.
102. 102. Spicer, D. B., Rhee, J., Cheung, W. L., and Lassar, A. B. (1996) Inhibition of myogenic bHLH and MEF2 transcription factors by the bHLH protein twist. Science 272, 1476-1480.
103. 103. Spizz, G., Roman, D., Strauss, A., and Olson, E. N. (1986) Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of cell proliferation. J. Cell Biol. 261, 9438-9488.
104. 104. Stockdale, F. E., and Holtzer, H. (1961) DNA synthesis and myogenesis. Exp. Cell Res. 24, 508-520.
105. 105. Stuart, E. T., and Gruss, P. (1996) PAX: developmental control genes in cell growth and differentiation? Cell Growth Differ. 7, 405-412.
106. 106. Stuart, E. T., Haffner, R., Oren, M., and Gruss, P. (1995) Loss of p53 function through PAX-mediated transcriptional repression. EMBO J. 14, 5638-5645.
107. 107. Tanabe, Y., and Jessell, T. M. (1996) Diversity and pattern in the developing spinal cord. Science 274, 1115-1123.
108. 108. Tapscott, S. J., Davis, R. L., Thayer, M. J., Cheng, P.-F., Weintraub, H., and Lassar, A. B. (1988) MyoD1: A nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts. Science 242, 405-411.
109. 109. Voyvodic, J. T. (1996) Cell death in cortical development: How much? Why? So what? Neuron 16, 693-696.
110. 110. Webster, K. A., Muscat, G. E. O., and Kedes, L. (1988) Adenovirus E1A products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters. Nature 332, 553-557.
111. 111. Weinberg, R. A. (1995) The retinoblastoma protein and cell cycle control. Cell 81, 323-330.
112. 112. Yaffe, D. (1968) Retention of differentiation potentialities during prolonged cultivation of myogenic cells. Proc. Natl. Acad. Sci. USA 61, 725-727.
113. 113. Yan, G.-z., and Ziff, E. B. (1995) NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1. J. Neurosci. 15, 6200-6212.
114. 114. Yang, X. J., Ogryzko, V. V., Nishikawa, J., Howard, B. H., and Nakatani, Y. (1996) A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382, 319-324.
115. 115. Yuan, W., Condorelli, G., Caruso, M., Felsani, A., and Giordano, A. (1996) Human p300 protein is a coactivator for the transcription factor MyoD. J. Biol. Chem. 271, 9009-9013.
116. 116. Yun, K., and Wold, B. (1996) Skeletal muscle determination and differentiation: Story of a core regulatory network and its context. Curr. Opin. Cell Biol. 8, 877-889.
117. 117. Zacksenhaus, E., Jiang, Z., Chung, D., Marth, J. D., Philips, R. A., and Gallie, B. (1996) pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev. 10, 3051-3064.