Structural immuno-analysis of human and porcine interferon gamma: Identification of shared antigenic domain

Cytokine

Volumn 9, Issue 8, 1997, Pages 550-555

  Kontsek, Peter ^a,b   Martens, Erik ^a   Vandenbroeck, Koen ^a   Kontseková, Eva ^c   Waschütza, Gero ^d   Sareneva, Timo ^e   Billiau, Alfons ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b INSTITUTE OF VIROLOGY   (Slovakia)

^c Physics and Informatics   (Slovakia)

^d FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^e NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ANTIGEN ANTIBODY REACTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CROSS REACTION; DISULFIDE BOND; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOGENICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; SWINE;

MURINAE; SUIDAE; SUS SCROFA; UNIDENTIFIED BACULOVIRUS;

EID: 0031214673     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1997.0200     Document Type: Article

References (17)

1. 1. Ealick SE, Cook WJ, Vijay-Kumar S, Carson M, Nagabhushan TL, Trotta PP, Bugg CE (1991) Three-dimensional structure of recombinant human interferon-gamma. Science 252:698-702.
2. 2. Samudzi CT, Burton LE, Rubin JR (199) Crystal structure of recombinant rabbit interferon-gamma at 2.7-A resolution. J Biol Chem 266:21791-21797.
3. 3. Vandenbroeck K, Martens E, D'Andréa S, Billiau A (1993) Refolding and single-step purification of porcine interferon-gamma from Escherichia coli inclusion bodies. Eur J Biochem 215:481-486.
4. 4. Alcami A, Smith GL (1992) A soluble receptor for interleukin-1 beta encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection. Cell 71:153-167.
5. 5. Rinderknecht E, O'Connor BH, Rodriguez H (198) Natural human interferon-gamma. J Biol Chem 259:6790-6797.
6. 6. Walter MR, Windsor WT, Nagabhushan TL, Lundell DJ, Lunn CA, Zavodny PJ, Narula SK (1995) Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor. Nature 376:230-235.
7. 7. Lunn CA, Fossetta J, Dalgarno D, Murgolo N, Windsor W, Zavodny PJ, Narula SK, Lundell D (1992) A point mutation of human interferon-gamma abolishes receptor recognition. Protein Eng 5:253-257.
8. 8. Vandenbroeck K, Willems L, Billiau A, Opdenakker G, Huybrechts R (1994) Glycoform heterogeneity of porcine interferon-gamma expressed in Sf9 cells. Lymphokine Cytokine Res 13:253-258.
9. 9. Slodowski O, Böhm J, Schöne B, Otto B (1991) Carboxy-terminal truncated rhIFN-γ with a substitution of Gln133 or Ser132 to leucine leads to higher biological activity than in the wild type. Eur J Biochem 202:1133-1140.
10. 10. Waschütza G, Li V, Schäfer T, Schomburg D, Zakaria H, Otto B (1995) Engineered disulfide bonds in recombinant human interferon-gamma: the impact of the N-terminal helix A and the AB-loop for protein stability. J Interferon Cytokine Res 15 (Suppl. 1): S141.
11. 11. Sareneva T, Pirhonen J, Cantell K, Kalkkinen N, Julkunen I (1994) Role of N-glycosylation in the synthesis, dimerization and secretion of human interferon-gamma. Biochem J 303:831-840.
12. 12. Heremans H, Van Damme J, Dillen C, Dijkmans R, Billiau A (1990) Interferon gamma, a mediator of lethal lipopolysaccharide-induced Shwartzman-like shock reaction in mice. J Exp Med 171:1853-1869.
13. 13. Kontseková E, Novák M, Kontsek P, Borecký L, Leśšo J (1988) The effect of postfusion cell density on establishment of hybridomas. Folia Biol (Praque) 34:18-22.
14. 14. Martens E, Dillen C, Put W, Heremans H, Van Damme J, Billiau A (1993) Increased circulating interleukin-6 (IL-6) activity in endotoxin-challenged mice pretreated with anti-IL-6 antibody is due to IL-6 accumulated in antigen-antibody complexes. Eur J Immunol 23:2026-2029.
15. 15. Sandvig S, Laskay T, Andersson J, De Ley M, Andersson U (1987) Gamma-interferon is produced by CD3+ and CD3-lymphocytes. Immunol Rev 97:51-65.
16. 16. Van der Meide PH, Dubbeld M, Vijverberg K, Kos T, Schellekens H (1986) The purification and characterization of rat gamma Interferon by use of two monoclonal antibodies. J Gen Virol 67:1059-1071.
17. 17. Kawade Y (1986) Quantitation of neutralization of interferon by antibody. Methods Enzymol 119:558-573.