Expression of the farnesyltransferase β-subunit gene in human ovarian carcinoma: Correlation to K-ras mutation

Gynecologic Oncology

Volumn 66, Issue 2, 1997, Pages 308-312

  Tanimoto, H ^a   Mehta, K D ^a   Parmley, T H ^a   Shigemasa, K ^b   Parham, G P ^a   Clarke, J ^a   O'Brien, T J ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b NATIONAL HOSPITAL ORGANIZATION KURE MEDICAL CENTER AND CHUGOKU CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYSTEINE; FARNESYL TRANSFERASE; MESSENGER RNA; RAS PROTEIN; TETRAPEPTIDE; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; BETA CHAIN; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; ONCOGENE K RAS; OVARY CARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0031214066     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1997.4750     Document Type: Article

References (16)

1. Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson J D. Molecular Biology of the Cell. 1994;Garland, New York. p. 763-.
2. Bos J L. ras. Cancer Res. 49:1989;4682-4689.
3. Bos J L, Fearon E R, Hamilton S R, Verlaan-de Vries M, van Boom J H, van der Eb A J, Vogelstein B. Prevalence ofras. Nature. 327:1987;293-297.
4. Newman C MH, Magee A I. Posttranslational processing of theras. Biochim Biophys Acta. 1155:1993;79-96.
5. Casey P J, Solski P A, Der C J, Buss J E. p21ras. Proc Natl Acad Sci USA. 86:1989;8323-8327.
6. Hancock J F, Magee A I, Childs J E, Marshall C J. Allras. Cell. 57:1989;1167-1177.
7. K-ras(B). EMBO J. 10:1991;641-646.
8. K, Shigemasa, C, Hu, C, M, West, S, H, Moon, G, P, Parham, T, H, Parmley, S, Korourian, V, V, Baker, T, J, O'Brien, 21p: A monitor of p53 dysfunction, Int J Gynecol Cancer.
9. Shigemasa K, Hu C, West C M, Clarke J, Parham G P, Parmley T H, Korourian S, Baker V V, O'Brien T J. p16 overexpression: A potential early indicator of transformation in ovarian carcinoma. J Soc Gynecol Invest. 1997.
10. Noonan K E, Beck C, Holzmayer T A, Chin J E, Wunder J S, Andrulis I L, Gazdar A F, Willman C L, Griffith B, Von Hoff D D, Roninson I B. Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. Proc Natl Acad Sci USA. 87:1990;7160-7164.
11. Willumsen B M, Christensen A, Hubbert N L, Papageorge A G, Lowy D R. The p21ras. Nature. 310:1984;583-586.
12. Gibbs J B. ras. Cell. 65:1991;1-4.
13. Gibbs J B, Oliff A, Kohl N E. Farnesyltransferase inhibitors:ras. Cell. 77:1994;175-178.
14. Sun J, Qian Y, Hamilton A D, Sebti S M. rasras. Cancer Res. 55:1995;4243-4247.
15. Fukuda Y, Takao T, Ohguro H, Yoshizawa T, Akino T, Shimonishi Y. Farnesylated γ-subunit of photoreceptor G protein indispensable for GTP-binding. Nature. 346:1990;658-660.
16. Glomset J A, Gelb M H, Farnsworth C C. Prenyl proteins in eukaryotic cells: A new type of membrane anchor. Trends Biochem Sci. 15:1990;139-142.