Co-transactivation of the 3' erythropoietin hypoxia inducible enhancer by the HIF-1 protein

Blood Cells, Molecules and Diseases

Volumn 23, Issue 2, 1997, Pages 169-176

  Madan, Ashima ^a,b   Varma, Sushama ^c   Cohen, Harvey J ^c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Division of Neonatology   (United States)

^c NONE

Author keywords

Co transactivation; Erythropoietin; Hypoxia

Indexed keywords

COMPLEMENTARY DNA; DNA BINDING PROTEIN; ERYTHROPOIETIN; LUCIFERASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; ENHANCER REGION; ERYTHROPOIESIS; GENE OVEREXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; HYPOXIA; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; TRANSACTIVATION;

ANIMALIA;

EID: 0031213514     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.1997.0134     Document Type: Article

References (21)

1. 1. Krantz SB. Erythropoietin. Blood 77: 419-434, 1991.
2. 2. Jelkman W. Erythropoietin. Structure, control of production and function. Physiol Rev 72:449-489. 1992.
3. 3. Jacobson LO, Goldwasser E, Fried W, Plzak L. Role of kidney in erythropoiesis. Nature 179:633-634. 1957.
4. 4. Fried W. The liver as a source of extrarenal Epo production. Blood 40:671-677. 1972.
5. 5. Beru N, McDonald J, Lacombe C, Goldwasser E. Expression of the erythropoietin gene. Mol Cell Biol 6:2571-2575, 1986.
6. 6. Bondurant MC, Koury MJ. Anemia induces accumulation of erythropoietin mRNA in the kidney and liver. Mol Cell Biol 6:2731-2733, 1986.
7. 7. Semenza GL. Regulation of Erythropoietin production. Hematol Oncol Clin N Am 8: 863-884, 1994.
8. 8. Wang GL, Semenza GL. General involvement of hypoxia inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci 90:4304-4308, 1993.
9. 9. Wang GL, Semenza GL. Characterization of hypoxia inducible factor 1 and regulation of DNA binding activity by hypoxia. J Biol Chem 268:21513-21518, 1993.
10. 10. Wang GL, Semenza GL. Purification and characterization of hypoxia-inducible Factor 1. J Biol Chem 270:1230-1237, 1995.
11. 11. Maxwell PH, Pugh CW, Ratcliffe PJ. Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: Evidence for a widespread oxygen-sensing system. Proc Natl Acad Sci USA 90:2423-2427, 1993.
12. 12. Madan A, Curtin P. A 24 base pair sequence 3′ to the human erythropoietin gene contains a hypoxia responsive transcriptional enhancer. Proc Natl Acad Sci USA 90:3928-3932, 1993.
13. 2 tension. Proc Natl Acad Sci USA 92:5510-5514, 1995.
14. 14. Semenza GL, Roth PH, Fang HM, Wang GL. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia inducible-factor 1. J Biol Chem 269:23757-23763, 1994.
15. 15. Levy AP, Levy NS, Wegner S, Goldberg. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem 270:13333-13340, 1995.
16. 16. Jiang BH, Rue E, Wang GL, Roe R, Semenza GL. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor-1. J Biol Chem 271:17771-17778, 1996.
17. 17. Semenza GL, Koury ST, Nejfelt MK, Gearhart JD, Antonarkis S. Cell type specific and hypoxia inducible expression of the human erythropoietin gene in transgenic mice. Proc Natl Acad Sci USA 88: 8725-8729, 1991.
18. 18. Madan A, Lin C, Hatch SL, Curtin PT. Regulated basal, inducible and tissue specific human Epo gene expression in transgenic mice requires multiple cis DNA sequences. Blood 85:2735-2741, 1995.
19. 19. Wood MS, Gleadle JM, Pugh CW, Hankinson O, Ratcliffe PJ. The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. J Biol Chem 271:15117-15123, 1996.
20. 20. Wenger RH, Rolfs A, Marti HH, Guenet JL, Gassman M. Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1α Biochem Biophys Res Commun 223:54-59, 1996.
21. 21. Huang LE, Arany Z, Livingston DM, Bunn HF. Activation of hypoxia -inducible transcription factor depends primarily upon redox sensitive stabilization of its alpha subunit. J Biol Chem 271(50):32253-32259, 1996.