Expression of HuD (a paraneoplastic encephalomyelitis antigen) mRNA in lung cancer

Journal of Korean Medical Science

Volumn 12, Issue 4, 1997, Pages 305-310

  Cho, Jeong Hee ^a   Noguchi, Masayuki ^b  

^a Dankook University   (South Korea)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Direct DNA sequencing; HuD gene; Non small cell lung cancer; RT PCR; Small cell lung cancer

Indexed keywords

ELAVL4 PROTEIN, HUMAN; HU ANTIGEN; MESSENGER RNA; NERVE PROTEIN; RNA BINDING PROTEIN; TUMOR ANTIGEN;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CLINICAL TRIAL; FEMALE; GENETIC TRANSCRIPTION; GENETICS; HUMAN; IMMUNOLOGY; LUNG TUMOR; MALE; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SMALL CELL CARCINOMA;

ANTIGENS, NEOPLASM; BASE SEQUENCE; CARCINOMA, SMALL CELL; FEMALE; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; LUNG NEOPLASMS; MALE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0031204808     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.1997.12.4.305     Document Type: Article

References (21)

1. Dalmau J, Furneaux HM, Rosenblum MK, Graus F, and Posner JB. Detection of anti-Hu antibody in specific regions of the nervous system and tumor from patients with paraneoplastic encephalomyelitis/sensory neuropathy. Neurology 1991 ; 41 : 1757-64.
2. Dalmau J, Graus F, Rosenblum MK, and Posner JB. Anti-Hu-associated paraneoplastic encephalomyelitis/sensory neuropathy : a clinical study of 71 patients. Medicine 1992 ; 71 : 59-72.
3. Dalmau J, Hurneaux HM, Gralla R, Kris M, and Posner JB. Detection of the anti-Hu antibody in the serum of patients with small cell lung cancer - a quantitative Western blot analysis. Ann Neurol 1990 ; 27 : 544-52.
4. Furneaux HF, Reich L, and Posner JB. Autoantibody synthesis in the central nervous system of patients with paraneoplastic syndromes. Neurology 1990 ; 40 : 1085-91.
5. Graus F, Cordon-Cardo C, and Posner JB. Neuronal anti-nuclear antibody in sensory neuropathy from lung cancer. Neurology 1985 ; 35 : 538-43.
6. Graus F, Elkon KB, Cordon-Cardo C, and Posner JB. Sensory-neuropathy and small cell lung cancer : Antinuclear antibody that also reacts with the tumor. Am J Med 1986 ; 80 : 45-52.
7. Dalmau J, Furneaux HM, Cordon-Cardo C, and Posner JB. The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuropathy) antigen in human normal and tumor tissues. Am J Pathol 1992 ; 141 : 881-6.
8. Budde-Steffen C, Anderson NE, Rosenblum MK, and Posner JB. Erpression of antigen in small cell lung carcinoma lines detected by antibody from patients with paraneoplastic dorsal root ganglinopathy. Cancer Res 1988 ; 48 : 430-34.
9. Szabo A, Dalmau J, Manley G, Rosenfeld M, Wong E, Henson J, Posner JB, Furneaux HM. HuD, a paraneoplastic encephalomyelitis antigen contains RNA-binding domains and is homologous to Elav and sex-lethal. Cell 1991 ; 67 : 325-33.
10. Robinow S, and White K. The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages. Dev Biol 1988 ; 126 : 294-303.
11. Deguchi T, Doi T, Ehara H, Ito S, Takahashi Y, Nishino Y, Fujihiro S, Kawamura T, Komeda H, Horie M, Kaji H, Shimokawa K, Tanaka T, and Kawada Y. Detection of micrometastatic prostate cancer cells in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res 1993 ; 53 : 5350-4.
12. Carney DN, Gazdar AF, Bepler G, Guccion JG, Marangos PJ, Moody TW, Zweig MH, and Minna JD. Establishment and identification of small cell lung cancer cell lines having classic and variant features. Cancer Res 1985 ; 45 : 2913-23.
13. Matsumoto T, Terasaki T, Mukai K, Wada M, Okamoto A, Yikota J, Yamaguchi K, Kato K, Nagatsu T, Shimosato Y. Relation between nucleolar size and growth characteristic in small cell lung cancer cell lines. Jpn J Cancer Res 1991 ; 82 : 820-8.
14. Colby TV, Koss MN, Travis WD. Tumors of the lower repiratory tract. Atlas of tumor pathology, third series, fascicle 13. Washington D.C., Armed Forces Institute of Pathology, 1995.
15. Sato Y, Mukai K, Watanabe S, Goto M, Shimosato Y. The AMeX method : a simple technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining. Am J Pathol 1986 ; 125 : 431-5.
16. Chomaczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987 ; 162 : 156-9.
17. Sambrook J, Fritsh EF, Maniatis T. Molecular cloning, A laboratory Manual 2. In : Fritsh EF, ed. NY : Cold Spring Harbor Laboratory, 1989 ; 726.
18. Cho JH, Noguchi M, Ochiai A, Uchino S, Hirohashi S. Analysis of regional differences of p53 mutation in advanced gastric carcinoma : relation to heterogeneous differentiation and invasiveness. Mod Pathol 1994 ; 17 : 205-11.
19. Higuchi RG, Ochman H. Production of single-strand DNA templates by exonuclease digestion following the polymerase reaction. Nucleic Acids Res 1989 ; 17 : 5865.
20. Noguchi M, Hirohashi S, Shimosato Y. Immunohistochemical detection of cluster 1 small cell lung cancer antigen and chromogranin A in lung carcinomas. Jpn J Cancer Res 1992 ; 22 : 10-6.
21. Sato Y, Mukai K, Furuya S, Shimosato Y. The AMeX method : a multipurpose tissue-processing and paraffin- embedding method. III Extraction and purification of RNA and application to slot-blot hybridization analysis. J Pathol 1991 ; 163 : 81-5.