Anti-platelet action of nitric oxide and selective phosphodiesterase inhibitors

Shock

Volumn 8, Issue 2, 1997, Pages 115-118

  Sly, M Kurt ^b,c   Eberhart, Robert C ^a,b   Prager, Morton D ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c Johnson and Johnson Medical Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; MILRINONE; NITRIC OXIDE; PHOSPHODIESTERASE INHIBITOR; PURINE DERIVATIVE; PYRIDONE DERIVATIVE; ZAPRINAST;

ANIMAL; ARTICLE; CELL CULTURE; DRUG EFFECT; RABBIT; THROMBOCYTE AGGREGATION;

ANIMALS; CELLS, CULTURED; MILRINONE; NITRIC OXIDE; PHOSPHODIESTERASE INHIBITORS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PURINONES; PYRIDONES; RABBITS;

EID: 0031204010     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199708000-00009     Document Type: Article

References (21)

1. Siess W: Molecular mechanisms of platelet activation. Physiol Rev 69:58-178, 1989.
2. Dohlman HG: Model systems for the study of seven-transmembrane segment receptors. Annu Rev Biochem 60:653-688, 1991.
3. 2 receptor. Nature 349:617-620, 1991.
4. Hwang S-B, Lan M-H, Pong S-S: Ionic and GTP regulation of binding of platelet-activating factor to receptors and platelet-activating factor -induced activation of GTPase in rabbit platelet membranes. J Biol Chem 261:532-537, 1986.
5. Tandon NN, Kralisz U, Jamieson GA: Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion. J Biol Chem 264:7576-7583, 1989.
6. 3H] dihydroergocryptine binding with aggregation and adenylate cyclase inhibition. J Clin Invest 61:1136-1144, 1978.
7. Greco NJ, Yamamoto N, Jackson BW, Tandon NN, Moos M, Jamieson GA: Identification of a nucleotide-binding site on glycoprotein lib. Relationship to ADP-induced platelet activation. J Biol Chem 266:13627-13633, 1991.
8. IIb/33 (platelet GPIIb-IIIa). Cell 65:409-416, 1991.
9. Baldassare JJ, Henderson PA, Burns D, Loomis C, Fisher GJ: Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels. J Biol Chem 267:15585-15590, 1992.
10. Radomski MW, Palmer RMJ, Moncada S: An arginine/nitric oxide pathway present in human platelets regulates aggregation. Proc Natl Acad Sci USA 87:5193-5197, 1990.
11. Sly MK, Prager MD, Li J, Harris FB, Shastri P, Bhujle R, Chao R, Kulkarni PV, Constantinescu A, Jessen MJ, Eberhart RC: Platelet and neutrophil distributions in pump- oxygenator circuits. I. Influence of nitric oxide gas infusion. ASAIO J 42:M494-M499, 1996.
12. Sly MK, Prager, MD, Eberhart RC, Jessen ME, Kulkarni PV: Inhibition of surface-induced platelet activation by nitric oxide. ASAIO J 41:M394-M398, 1995.
13. Doyle MP, Hoekstra JW: Oxidation of nitrogen oxides by bound dioxygen in hemoproteins. J Inorg Biochem 14:351-358, 1981.
14. Beavo JA, Reisfsnyder DH: Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. Trends Pharmacol Sci 11:150-155, 1990.
15. Nicholson CD, Challiss RAJ, Shahid M: Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes. Trends Pharmacol Sci 12:19-27, 1991.
16. Lindgren SHS, Andersen TLG, Vinge E, Andersson K-E: Effects of isozyme-selective phosphodiesterase inhibitors on rat aorta and human platelets: smooth muscle tone, platelet aggregation and cAMP levels. Acta Physiol Scand 140:209-219, 1990.
17. Simpson AWM, Reeves ML, Rink TJ: Effects of SK&F 94120, an inhibitor of cyclic nucleotide phosphodiesterase type III, on human platelets. Biochem Pharmacol 37:2315-2320, 1988.
18. Robichon A: A new cGMP phosphodiesterase isolated from bovine platelets is substrate for cAMP- and cGMP-dependent protein kinases: evidence for a key role in the process of platelet activation. J Cell Biochem 47:147-157, 1991,
19. Anderson TLG, Vinge E: Interaction between isoprenaline, sodium nitroprusside, and isozyme-selective phosphodiesterase inhibitors on ADP-induced aggregation and cyclic nucleotide levels in human platelets. J Cardiovasc Pharmacol 18:237-242, 1991.
20. Mellion BT, Ignarro LJ, Ohlstein EH, Pontecorvo EG, Hyman AL, Kadowitz PJ: Evidence for the inhibitory role of guanosine 3′,5′-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators. Blood 57:946-955, 1981.
21. Nguyen BL, Saitoh M, Ware, JA: Interaction of nitric oxide and cGMP with signal transduction in activated platelets. Am J Physiol 261:H1043-H1052, 1991.