Structure-Activity and Mechanism Studies on Silicon Phthalocyanines with Plasmodium falciparum in the Dark and under Red Light

Photochemistry and Photobiology

Volumn 66, Issue 2, 1997, Pages 282-287

  Zhao, Xiao Juan ^a   Lustigman, Sara ^b   Kenney, Malcolm E ^c   Ben Hur, Ehud ^a  

^a VI Technologies Inc   (United States)

^b NEW YORK BLOOD CENTER   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMODIUM FALCIPARUM;

ANTIMALARIAL AGENT; BIS(TRI N HEXYLSILOXY)(2,3 NAPHTHALOCYANINATO)SILICON; BIS(TRI-N-HEXYLSILOXY)(2,3-NAPHTHALOCYANINATO)SILICON; INDOLE DERIVATIVE; ORGANOSILICON DERIVATIVE; PHOTOSENSITIZING AGENT; SILANE DERIVATIVE; SILICON PHTHALOCYANINE;

ANIMAL; ARTICLE; DARKNESS; DRUG EFFECT; ELECTRON MICROSCOPY; LIGHT; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE;

ANIMALS; ANTIMALARIALS; DARKNESS; INDOLES; LIGHT; MICROSCOPY, ELECTRON; ORGANOSILICON COMPOUNDS; PHOTOSENSITIZING AGENTS; PLASMODIUM FALCIPARUM; SILANES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031196339     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1997.tb08656.x     Document Type: Article

References (22)

1. Grant, D. B., M. S. Perinpanayagem, P. G. Shute and R. A. Zeitlin (1960) A case of malignant tertian (Plasmodium falciparum) malaria after blood transfusion. Lancet 2, 469-470.
2. Chojnacki, R. E., J. H. Brazinsky and O. Barrett (1968) Transfusion-induced falciparum malaria. N. Engl. J. Med. 279, 984-985.
3. Espinal, C. A. and P. De Morales (1984) Indirect ELISA test for malaria in blood donors. Trans. Soc. Trop. Med. Hyg. 78, 645-647.
4. Nahlen, B. L., H. O. Lobel, S. E. Cannon and C. C. Campbel (1991) Reassessment of blood donor selection criteria for United States travelers to malarious areas. Transfusion 31, 798-804.
5. Basco, L. K., P. Eldin de Pecoules, C. M. Wilson, J. Le Bras and A. Mazabraud (1995) Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanyl resistance in Plasmodium falciparum. Mol. Biochem. Parasitol. 69, 135-138.
6. Bzik, D. J., W. B. Li, T. Horii and J. Inselburg (1987) Molecular cloning and sequence analysis of the Plasmodium falciparum hydrofolate reductase-thymidylate synthase gene. Proc. Natl. Acad. Sci. USA 84, 8360-8364.
7. Brooks, D. R., P. Wang, M. Reed, W. M. Watkins, P. F. G. Sims and J. E. Hyde (1994) Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite Plasmodium falciparum, with differing resistance to sulfadoxine. Eur. J. Biochem. 224, 397-405.
8. Horowitz, B., B. Williams, S. Rywkin, A. M. Prince, D. Pascual, N. Geacintov and J. Walinsky (1991) Inactivation of viruses in blood with aluminum phthalocyanine derivatives. Transfusion 31, 102-108.
9. Rywkjn, S., E. Ben-Hur, Z. Malik, A. M. Prince, Y. S. Lee, M. E. Kenney, N. L. Oleinick and B. Horowitz (1994) New phthalocyanines for photodynamic virus inactivation in red blood cell concentrates. Photochem. Photobiol. 60, 165-170.
10. Ben-Hur, E.. S. Rywkin, I. Rosenthal, N. E. Geacintov and B. Horowitz (1995) Virus inactivation in red cell concentrates by photosensitization with phthalocyanines: protection of red cells but not of vesicular stomatitis virus with a water-soluble analog of vitamin E. Transfusion 35, 401-406.
11. Gottlieb, P., L. G. Shen, E. Chimezie, S. Bahng, M. E. Kenney, B. Horowitz and E. Ben-Hur (1995) Inactivation of Trypanosoma cruzi trypomastigote forms in blood components by photodynamic treatment with phthalocyanines. Photochem. Photobiol. 62, 869-874.
12. Lustigman, S. and E. Ben-Hur (1996) Photosensitized inactivation of Plasmodium falciparum in human erythrocytes by phthalocyanines. Transfusion 36, 543-546.
13. Oleinick, N. L., A. R. Antunez, M. E. Clay, B. D. Rihter and M. E. Kenney (1993) New phthalocyanine photosensitizers for photodynamic therapy. Photochem. Photobiol. 57, 242-247.
14. Esposito, J. N., J. E. Lloyd and M. E. Kenney (1966) The synthesis and physical properties of some organo-and organosiloxysilicon phthalocyanines. Inorg. Chem. 5, 1979-1984.
15. Trager, W. and B. Jensen (1976) Human malaria parasites in continuous culture. Science 193, 673-675.
16. Trager, W. (1994) Cultivation of malaria parasites. Methods Cell Biol. 45, 7-25.
17. O'Neill, M. J., D. H. Bray, P. Boardman, J. D. Phillipson and D. C. Warhurst (1985) Plants as sources of amimalarial drugs. Part 1. In vitro test method for the evaluation of crude extracts from plants. Planta Med. 47, 394-397.
18. Lustigman, S., R. F. Anders, G. V. Brown and R. L. Coppel (1988) A component of an antigenic rhoptry complex of Plasmodium falciparum is modified after merozoite invasion. Mol. Biochem. Parasitol. 30, 217-224.
19. Makler, M. T., J. M. Ries, J. A. Willams, J. E. Bancroft, R. C. Piper, B. L. Gibbins and D. J. Hinrichs (1993) Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity. Am. J. Trop. Med. Hyg. 48, 739-741.
20. Basco, L. K., F. Marquet, M. M. Makler and J. Bras (1995) Plasmodium falciparum and Plasmodium vivax: lactate dehydrogenase activity and its application for in vitro drug susceptibility assay. Exp. Parasitol. 80, 260-270.
21. Ben-Hur, E. and B. Horowitz (1995) Advances in photochemical approaches for blood sterilization. Photochem. Photobiol. 62, 383-388.
22. Ben-Hur, E. and B. Horowitz (1996) Virus inactivation in blood. AIDS 10, 1183-1190.