Teratogenicity of methanol following a single oral dose in Long-Evans rats

Reproductive Toxicology

Volumn 11, Issue 4, 1997, Pages 503-510

  Youssef, Ashraf F ^a,d   Baggs, Raymond B ^a,b   Weiss, Bernard ^a   Miller, Richard K ^a,c  

^a Environmental Health Sciences Center   (United States)

^b Div of Laboratory Animal Medicine   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d TAP Holdings Inc   (United States)

Author keywords

Methanol; Oral; Rats; Teratogenicity

Indexed keywords

METHANOL; MINERAL OIL;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOPHTHALMIA; ARTICLE; BODY WEIGHT; CHEMICAL TERATOGENESIS; CONGENITAL MALFORMATION; CONTROLLED STUDY; CRYPTORCHISM; DOSE RESPONSE; DRUG EFFECT; EXOPHTHALMOS; FEMALE; FETUS; FETUS WEIGHT; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PREGNANCY; RAT; TERATOGENICITY; WEIGHT REDUCTION;

ABNORMALITIES, DRUG-INDUCED; ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; MALE; METHANOL; PREGNANCY; RATS;

ANIMALIA;

EID: 0031195305     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(97)00017-8     Document Type: Article

References (43)

1. 1. Potts AM. Duality of optic nerve in toxicology. In: Merigan WH, Weiss B, eds. Neurotoxicity of the visual system. New York: Raven Press; 1980:1-5.
2. 2. Environmental Protection Agency (EPA). Summary review of health effects associated with methanol: health issue assessment. Research and development preliminary draft ECAD-R-134A. 1987.
3. 3. Greizerstein HB. Congener contents of alcoholic beverages. J Stud Alcohol. 1981;42:1030-7.
4. 4. Youssef AF, Weiss B. The toxicity of ethanol-methanol combination. Arch Compl Environ Stud. 1990;2:23-30.
5. 5. Anzimlt KC. Methanol levels in methylated spirits drinking alcoholics. N Z Med J. 1986;99:764-5.
6. 6. Jones AW. Abnormally high concentrations of methanol in breath: a useful biochemical marker of recent heavy drinking. Clin Chem. 1986;32:1241-2.
7. 7. Streissguth AP, Landesman-Dwyer S, Martin JC, Smith DW. Teratogenic effects of alcohol in humans and laboratory animals. Science. 1980:209:353-61.
8. 8. Nelson BK, Brightwell WS, MacKenzie OR, Khan A, Burg JR. Weigel WW, Goad PT. Teratological assessment of methanol and ethanol at high inhalation levels in rats. Fundam Appl Toxicol. 1985;5:727-36.
9. 9. New Energy Development Organization (NEDO). Toxicological research of methanol as a fuel for power stations, Tokyo (personal communication, 1987).
10. 10. De-Carvalho RR, Delgado IF, Souza CAM, Chahoud I, Paumgartten FJR. Embryotoxicity of methanol in well-nourished and malnourished rats. Braz J Med Biol Res. 1994:27:2915-23.
11. 11. Stanton ME, Crofton KM, Gray LE, Gordon CM, Boyes WK, Mole ML, Peele DB, Bushnell PJ. Assessment of offspring development and behavior following gestational exposure to inhaled methanol in the rat. Fundam Appl Toxicol. 1995;28:100-10.
12. 12. Infurna R, Weiss B. Neonatal behavioral toxicity in rats following prenatal exposure to methanol. Teratology. 1986:33:259-65.
13. 13. Bolon B, Dorman DC, Janszen D, Waisen F. Phase specific developmental toxicity in mice follwoing maternal methanol inhalation. Fundam Appl Toxciol. 1993;49:497-517.
14. 14. Rogers JM, Mole ML, Chernoff N, Barbee BD, Turner CI, Lodgsdon TR, Kavlock RJ. The developmental toxicity of inhaled methanol in the CD-1 mouse, with quantitative dose-response modeling for estimation of benchmark doses. Teratology. 1993;47:175-88.
15. 15. Youssef AF, Madkour K, Cox C, Weiss B. The lethality of ethyl alcohol, methyl alcohol, and mixtures. J Appl Toxicol. 1992;12: 193-7.
16. 16. Moser VC, McCormick JP, Creason JP, MacPhail RC. Comparison of chlordimeform and carbaryl using a functional observational battery. Fundam Appl Toxicol. 1988:11:189-216.
17. 17. Wilson, JG. Embryological considerations in teratology. In: Wilson JG, Warkany J, eds. Teratology principles and techniques. Chicago: The University of Chicago Press; 1965:251-77.
18. 18. Dawson AB. A note on the stanining of the skeleton of cleared specimens with Alizarin Red S. Stain Technol. 1926;1:123-4.
19. 19. White TEK, Baggs RB, Miller RK. Central nervous system lesions in Wistar rat fetus following direct fetal injections of cadmium. Teratology. 1990;42:7-13.
20. 20. Beaudoin AR. Embryology and teratology. In: Baker HJ, Lindsey JR, Weisbroth SH, eds. The laboratory Rat, vol II. New York: Wiley and Sons; 1980:85.
21. 21. Manson JM, Zenick H, Saltzman RA. Teratology test method for laboratory animals. In: Hayes AW, ed. Principles and methods of toxicology. New York: Raven Press; 1982:141-84.
22. 22. Yager RM, Abel EL. Effects of methanol on pregnant rats and their offspring. Alcohol Clin Exp Res. 1990;14:354.
23. 23. Youssef EH, Raslan NA. Study of the factors which affect the descent of the testicles in man. Acta Anat (Basel). 1971;79:422-44.
24. 24. Radhakrishnan J, Morikawa Y, Donahoe PK, Handren WH. Observations on the gubernaculum during descent of the testis. Invest Urol. 1971;16:365.
25. 25. Moore KL. The developing human. In: Clinically oriented embryology, 4th ed. Philadelphia: W.B. Saunders Company; 1988.
26. 26. Baggs RB, Miller RK, German R, McKenzie RC. Teratogenic and neoplastic lesions of genitourinary system in Wistar rats exposed in utero to diethylstilbestrol (DES). Teratology. 1980;21:26A.
27. 27. Lee PA. Fertility in cryptorchidism. Does treatment make a difference? Endocrinol Metab Clin North Am. 1993;22:479-90.
28. 28. Cameron AM, Nelson OG, Haug E, Eik-Nes KB. Circulating concentrations of testosterone, luteinizing hormone and follicle stimulating hormone in male rats after inhalation of methanol. Arch Toxicol Suppl. 1984;7:441-3.
29. 29. Cooper RL, Mole ML, Rehnberg GL, Goldman JM, McElroy WK, Hein J, Stoker TE. Effect of inhaled methanol on pituitary and testicular hormones in chamber acclimated and nonacclimated rats. Toxicology. 1992;71:69-81.
30. 30. Coulombre AJ, Coulombre JL. Abnormal organogenesis in the eye. In: Wilson JG, Fraser FC, eds. Handbook of teratology, 2, mechanisms and pathogenesis. New York: Planeum Press; 1977:329-41.
31. 31. Hayreh MS, Hayreh G, Baumbach P, Cancilla G, Martin-Amat K, Tephly TR. Ocular toxicity of methanol: an experimental study. In: Merigan WH, Weiss B, eds. Neurotoxicity of the visual system. New York: Raven Press; 1980:33-5.
32. 32. Murray TG, Burton TC, Rajani C, Lewandowski MF, Burke JM, Eells JT. Methanol poisoning: a rodent model with structural and functional evidence for retinal involvement. Arch Opthalmol. 1991:109:1012-6.
33. 33. Neymeyer VR, Tephly TR. Detection and quantification of 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) in rat retina, optic nerve, and brain. Life Sci. 1994;54:395-9.
34. 34. Elles JT, Salzman MM, Ramirez. Formate-induced inhibition of retinal mitochondrial ATP synthesis. Fundam Appl Toxicol. 1996; 1:123.
35. 35. Perez-D'Gregorio RE, Miller RK. Teratogenicity of tellurium dioxide: prenatal assessment. Teratology. 1988;37:307-16.
36. 36. Shepard TH. Catalog of teratogenic agents. Baltimore: The Johns Hopkins University Press; 1986:1.
37. 37. Black KA, Elles JT, Noker PE, Hawtrey CA, Tephly TR. Role of hepatic tetrahydrofolate in species differences in methanol toxicity. Proc Natl Acad Sci USA. 1985:82:3845-58.
38. 38. El-Sayed NM, Abdel-Khalek CR, Gaafar KM, Kamal L. Methyl alcohol induced acidosis and retinal changes in rats. Egypt Med J. 1989;6:411-23.
39. 39. Horton VL, Higuchi MA, Rickert DE. Physiologically based pharmacokinetics model for methanol in rats, monkeys and humans. Toxicol Appl Pharmcol. 1992;117:26-36.
40. 40. Kavet R, Nauss KM. The toxicity of inhaled methanol vapors. CRC Crit Rev Toxicol. 1990;21:21-50.
41. 41. Kane RL, Talbert W, Harlen J. A methanol poisoning outbreak in Kentucky: a clinical epidemiological study. Arch Environ Health. 1968;17:119-29.
42. 42. Benton CD, Calhoun FP. The ocular effects of methyl alcohol poisoning: report on catastrophe involving 320 cases. Trans Am Acad Ophthalmol Otolaryngol. 1953:56:875-85.
43. 43. Boeckx RL, Cooding FL. An epidemic of gasoline sniffing. In: Sharp CW, Carroll LT, eds. Voluntary inhalation of industrial solvents. Maryland: National Institute on Drug Abuse, U.S. DHEW; 1987:179-86.