Selective precipitation of antibody with ligand-modified phospholipids: Effect of lipid chain length

Biotechnology Progress

Volumn 13, Issue 4, 1997, Pages 446-452

  Kilpatrick, Peter K ^a   Lisi, James F ^a   Carbonell, Ruben G ^a  

^a North Carolina State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPOSITION EFFECTS; CRITICAL MICELLE CONCENTRATION; LIGHT SCATTERING; LIPIDS; MATHEMATICAL MODELS; MOLECULAR STRUCTURE; PRECIPITATION (CHEMICAL); REACTION KINETICS;

LIGAND MODIFIED PHOSPHOLIPIDS; MIE THEORY; POLYCLONAL ANTIBIOTIN ANTIBODY; SMOLUCHOWSKI THEORY;

ANTIBODIES;

EID: 0031194089     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp9700521     Document Type: Article

References (10)

1. Adamson, A. W. Physical Chemistry of Surfaces, 4th ed.; Wiley: New York, 1982.
2. Bayer, E. A.; Rivnay, B.; Skutelsky, E. On the mode of liposome-cell interactions: biotin-conjugated lipids as ultrastructural probes. Biochim. Biophys. Acta 1979, 464-473, 550.
3. Guzman, R. Z.; Kilpatrick, P. K.; Carbonell, R. G. Affinity precipitation of avidin using ligand-modified surfactants. Downstream Processing and Bioseparation: Recovery and Purification of Biological Products; Hamel, J. F., Hunter, J. B., Sikdar, S. K., Eds.; ACS Symposium Series 419; American Chemical Society: Washington, DC, 1990; pp 212-236.
4. Harkins, W. D.; Jordan, H. F. J. Am. Chem. Soc. 1930, 52, 1772.
5. Powers, D. D.; Willard, B.; Carbonell, R. G.; Kilpatrick, P. K. Affinity precipitation of proteins by surfactant-solubilized ligand-modified phospholipids. Biotechnol. Prog. 1992, 8, 436-453.
6. Powers, D. D.; Carbonell, R. G.; Kilpatrick, P. K. Selective precipitation of antibodies with ligand-modified phospholipids. Biotechnol. Bioeng. 1994, 44, 509-522.
7. Powers, J. D.; Kilpatrick, P. K.; Carbonell, R. G. Protein purification by affinity binding to unilamellar vesicles. Biotechnol. Bioeng. 1989, 33, 1267-1276.
8. Tanford, C. The Hydrophobic Effect, 2nd ed.; Wiley: New York, 1980.
9. Tausk, R. J. M.; Karmiggelt, J.; Oudshoorn, C.; Overbeek, J. Th. G. Physical chemical studies of short-chain lecitihin homologues. I. Influence of the chain length of the fatty acid ester and of electrolytes on the critical micelle concentration. Biophys. Chem. 1974a, 1, 175.
10. Tausk, R. J. M.; Van Esch, J.; Karmiggelt, J.; Voordouw, G.; Overbeek, J. Th. G. Physical chemical studies of short-chain lecitihin homologues. II. Micellar weights of dihexanoyl-and diheptanoyllecithin. Biophys. Chem. 1974b, 1, 184.