Hepatoprotective effect of a nonselective endothelin receptor antagonist (TAK-044) in the transplanted liver

Journal of Surgical Research

Volumn 70, Issue 2, 1997, Pages 156-160

  Yamanaka, Naoki ^a   Takaya, Yutaka ^a   Oriyama, Takeshi ^a   Furukawa, Kazutaka ^a   Tanaka, Tsuneo ^a   Tanaka, Wataru ^a   Ichikawa, Nobutaka ^a   Yasui, Chiaki ^a   Ando, Tatsuya ^a   Yamanaka, Junichi ^a   Kuroda, Nobukazu ^a   Ko, Motohiro ^a   Takada, Masafumi ^a   Imakita, Masamichi ^a   Kitayama, Yoshihiro ^a   Okamoto, Eizo ^a   Sasaki, Sadao ^a   Nakagaki, Ikuko ^a   Hori, Seiki ^a   Ito, Takaaki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BILE ACID; BILIRUBIN; CALCIUM; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; EURO COLLINS SOLUTION; INDOCYANINE GREEN; LIVER ENZYME; RINGER LACTATE SOLUTION; TAK 044;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON PROBE MICROANALYSIS; ENZYME IMMUNOASSAY; FEMALE; LIVER; LIVER BIOPSY; LIVER BLOOD FLOW; LIVER FUNCTION TEST; LIVER PROTECTION; LIVER TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; SWINE; TRANSMISSION ELECTRON MICROSCOPY; X RAY MICROANALYSIS;

EID: 0031194065     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1997.5116     Document Type: Article

References (32)

1. Yanagisawa M., Kurihara H., Kimura S., Tomobe Y., Kobayashi M., Mitsui Y., Yazaki Y., Goto K., Masaki T. A novel potent vaso-constrictor peptide produced by vascular endothelial cells. Nature. 332:1988;411.
2. Goto M., Takei Y., Kawano S., Nagano K., Tsuji S., Masuda E., Nishimura Y., Okamura S., Kashiwagi T., Fusamoto H., Kamada T. Endothelin-1 is involved in the pathogenesis of ischemia/reperfusion liver injury by hepatic microcirculatory disturbances. Hepatology. 19:1994;675.
3. Okumura S., Takei Y., Kawano S., Nagano K., Masuda E., Goto M., Tsuji S., Michida T., Chen S. S., Kashiwagi T., Fusamoto H., Kamada T., Sato N. Vasoconstrictive effect of endothelin-1 on rat liver in vivo. Hepatology. 19:1994;155.
4. Kawamura E., Yamanaka N., Okamoto E., Tomoda F., Furukawa K. Response of plasma and tissue endothelin-1 to liver ischemia and its implication in ischemia-reperfusion injury. Hepatology. 21:1995;1138.
5. Y. Kitayama, N. Yamanaka, E. Kawamura, N. Kuroda, E. Okamoto, Hepatoprotective effect of the endothelin receptor antagonist TAK-044 against ischemia-reperfusion injury in the liver, Hepatology.
6. Lerman A., Click R. L., Narr B. J., Wiesner R. H., Krom R. A. F., Textor S. C., Burnett J. C. Elevation of plasma endothelin associated with systemic hypertension in humans following orthotopic liver transplantation. Transplantation. 51:1991;646.
7. Kikuchi T., Ohtaki T., Kawata A., Imada T., Asami T., Masuda Y., Sugo T. Cyclic hexapeptide endothelin receptor antagonist highly potent for both receptor subtypes ETA and ETB. Biochem. Biophys. Res. Commun. 200:1994;1708.
8. Buja J. E., Burton K. P., Haglar H. K., Willerson J. T. Quantitative X-ray microanalysis of the elemental composition of individual myocytes in hypoxic rabbit myocardium. Circulation. 69:1983;872.
9. Von Zglinicke T., Rimmler M., Purz H. J. Best cryosection technique for X-ray microanalysis. J. Microsc. 141:1986;79.
10. Somlyo A. P. Cell calcium measurement with electron probe and electron energy loss analysis. Cell Calcium. 6:1983;197.
11. Sasaki S., Nakagaki I., Mori H., Imai Y. Intracellular calcium store and transport of elements in acinar cells of the salivary gland determined by electron probe X-ray microanalysis. Jpn. J. Physiol. 33:1983;69.
12. Suzuki N., Matumoto H., Kitada C., Masaki T., Fujino M. A sensitive sandwich-enzyme immunoassay for human endothelin. J. Immunol. Methods. 118:1989;245.
13. Ohlstein E. H., Nambi P., Douglas S. A., Edwards R. M., Gellai M., Lago A., Leber J. D., Cousins R. D., Gao A., Frazee J. S. SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist. Proc. Natl. Acad. Sci. USA. 91:1994;8052.
14. Clozel M., Breu V., Gray G. A., Kalina B., Loffler B. M., Burri K., Cassal J. M., Hirth G., Muller M., Neidhart W. Pharmacological characterization of Bosentan, new potent orally active nonpeptide endothelin receptor antagonist. JPET. 270:1994;228.
15. Awane Y., Kusumoto K., Kubo K. Pharmacological profile in vitro of a new endothelin receptor antagonist, TAK-044. Jpn. J. Pharmacol. 64:1994;167.
16. Ikeda S., Awane Y., Kusumoto K., Wakimasu M., Watanabe T., Fujino M. A new endothelin receptor antagonist, TAK-044, shows long-lasting inhibition of both ETA- and ETB-mediated blood pressure responses in rats. J. Pharmacol. Exp. Ther. 270:1994;728.
17. Watanabe T., Awane Y., Ikeda S., Fujiwara S., Kubo K., Kikuchi T., Kusumoto K., Wakimastu M., Fujino M. Pharmacology of a non selective ETA and ETB receptor antagonist, TAK-044, and the inhibition of myocardial infarct size in rats. Br. J. Pharmacol. 114:1995;949.
18. Kusumoto K., Kubo K., Kandori H., Kitayoshi T., Sato S., Wakimatsu M., Watanabe T., Fujino M. Effects of a new endothelin antagonist, TAK-044, on post-ischemic acute renal failure in rats. Life Sci. 55:1994;301.
19. Housset C., Rockey D. C., Bissell D. M. Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin-1. Proc. Natl. Acad. Sci. USA. 90:1993;9266.
20. Kawada N., Tran-Thi T., Klein H., Decker K. The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Eur. J. Biochem. 213:1993;815.
21. Zhang J. X., Pegoli W. Jr., Clemens M. G. Endothelin-1 induces direct constriction of hepatic sinusoids. Am. J. Physiol. 266:1994;G624.
22. Hochachka P. W. Defence strategies against hypoxia and hypothermia. Science. 231:1986;234.
23. Somlyo A. P., Bond M., Somlyo A. V. Calcium content of mitochondria and endoplasmic reticulum in liver frozen rapidly in vivo. Nature. 314:1985;622.
24. Somlyo A. P. Cellular site of calcium regulation. Nature. 309:1984;516.
25. Duchen M. R., Peuchen S., Nowicky A. Changes in mitochondrial function in response to changes in cytosolic Ca++ concentration. Biomed. Res. 14:1993;139.
26. Carafoli E. Intracellular calcium homeostasis. Annu. Rev. Biochem. 56:1987;395.
27. Gal C. S. L., Jouneaux C., Sanchez Bueno A., Raufaste D., Roche B., Preaux A. M., Maffrand J. P. Endothelin activation in rat liver. J. Clin. Invest. 87:1991;133.
28. Tanaka A., Katagiri K., Hoshino M., Hayakawa T., Tsukada K., Takeuchi T. Endothelin-1 stimulates bile acid secretion and vesicular transport in the isolated perfused rat liver. Am. J. Physiol. 266:1994;G324.
29. Gandhi C. R., Behal R. H., Harvey S. A. K., Nouch T. A., Olson M. S. Hepatic effect of endothelin. Biochem. J. 287:1992;897.
30. Striggow F., Bohnensack R. Verapamil and diltiazem inhibit receptor-operated calcium channels and intracellular calcium oscillations in rat hepatocytes. FEBS Lett. 318:1993;341.
31. Rakugi H., Tabuchi Y., Nakamaru M., Nagano M., Higashimori K., Mikami H., Ogihara T. Evidence for endothelin-1 release from resistance vessels of rats in response to hypoxia. Biochem. Biophys. Res. Commun. 169:1990;973.
32. Yu P. C., Kuo J. S., Lin H. C., Yang M. C. Effect of endothelin in portal hypertensive rats. Clin. Sci. 83:1992;165.