Requirement of CD4 T Cells for Skin Graft Rejection Against Thymus Leukemia (TL) Antigen and Multiple Epitopes on the TL Molecule Recognized by CD4 T Cells

Journal of Immunology

Volumn 159, Issue 1, 1997, Pages 159-166

  Tsuji, Kazuhide ^b   Obata, Yuichi ^b   Takahashi, Toshitada ^b   Arata, Jiro ^b   Nakayama, Eiichi ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; TUMOR ANTIGEN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; C3H MOUSE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; EPITOPE MAPPING; GENETICS; GRAFT REJECTION; IMMUNOLOGY; MOLECULAR GENETICS; MOUSE; SKIN TRANSPLANTATION; T CELL LEUKEMIA;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, NEOPLASM; CD4-POSITIVE T-LYMPHOCYTES; EPITOPE MAPPING; EPITOPES; GRAFT REJECTION; IMMUNITY, CELLULAR; LEUKEMIA, T-CELL; MICE; MICE, INBRED C3H; MOLECULAR SEQUENCE DATA; SKIN TRANSPLANTATION;

EID: 0031182986     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Klein, J., Z. Zhu, J. Gutknecht, F. Figueroa, and M. Kasahara. 1991. Mhc: lessons in evolution. In Immunogenetics of the Major Histocompatibility Complex. R. Srivastava, B. P. Ram, and P. Tyle, eds. VCH, New York, p. 18.
2. Steinmetz, M., A. Winoto, K. Minard, and L. Hood. 1982. Clusters of genes encoding mouse transplantation antigens. Cell 28:489.
3. Campbell, R. D., and J. Trowsdale. 1993. Map of the human MHC. Immunol. Today 14:349.
4. Shawar, S. M., J. M. Vyas, J. R. Rodgers, and R. R. Rich. 1994. Antigen presentation by major histocompatibility complex class I-b molecules. Annu. Rev. Immunol. 12:839.
5. Loveland, B., C.-R. Wang, H. Yonekawa, E. Hermel, and K. Fischer Lindahl. 1990. Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein. Cell 60:971.
6. Shawar, S. M., R. G. Cook, J. R. Rodgers, and R. R. Rich. 1990. Specialized functions of MHC class I molecules. I. An N-formyl peptide receptor is required for construction of the class I antigen Mta. J. Exp. Med. 171:897.
7. Shawar, S. M., J. M. Vyas, J. R. Rodgers, R. G. Cook, and R. R. Rich. 1991. Specialized functions of major histocompatibility complex class I molecules. II. Hmt binds N-formylated peptides of mitochondrial and prokaryotic origin. J. Exp. Med. 174:941.
8. Rötzschke, O., K. Falk, S. Stevanovic, B. Grahovac, M. J. Soloski, G. Jung, and H.-G. Rammensee. 1993. Qa-2 molecules are peptide receptors of higher stringency than ordinary class I molecules. Nature 361:642.
9. Joyce, S., P. Tabaczewski, R. H. Angeletti, S. G. Nathenson, and I. Stroynowski. 1994. A nonpolymorphic major histocompatibility complex class Ib molecule binds a large array of diverse self-peptides. J. Exp. Med. 179:579.
10. Old, L. J., and E. Stockert. 1977. Immunogenetics of cell surface antigens of mouse leukemia. Annu. Rev. Genet. 11:127.
11. Chen, Y.-T., Y. Obata, E. Stockert, T. Takahashi, and L. J. Old. 1987. Tla-region genes and their products. Immunol. Res. 6:30.
12. Boyse, E. A., L. J. Old, and S. Luell. 1963. Antigenic properties of experimental leukemias. II. Immunological studies in vivo with C57BL/6 radiation-induced leukemias. J. Natl. Cancer Inst. 31:987.
13. Hershberg, R., P. Eghtesady, B. Sydora, K. Brorson, H. Cheroutre, R. Modlin, and M. Kronenberg, 1990. Expression of the thymus leukemia antigen in mouse intestinal epithelium. Proc. Natl. Acad. Sci. USA 87:9727.
14. Wu, M., L. V. Kaer, S. Itohara, and S. Tonegawa. 1991. Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells. J. Exp. Med. 174:213.
15. Obata, Y., O. Taguchi, Y. Matsudaira, H. Hasegawa, N. Hamasima, and T. Takahashi. 1991. Abnormal thymic development, impaired immune function and γδ T cell lymphomas in a TL transgenic mouse strain. J. Exp. Med. 174:351.
16. Morita, A., T. Takahashi, E. Stockert, E. Nakayama, T. Tsuji, Y. Matsudaira, L. J. Old, and Y. Obata. 1994. TL antigen as a transplantation antigen recognised by TL-restricted cytotoxic T cells. J. Exp. Med. 179:777.
17. Hamasima, N., T. Takahashi, O. Taguchi, Y. Nishizuka, R. Stockert, L. J. Old, and Y. Obata. 1989. Expression of TL, H-2, and chimeric H-2/TL genes in transgenic mice: abnormal thymic differentiation and T-cell lymphomas in a TL transgenic strain. Proc. Natl. Acad. Sci. USA 86:7995.
18. Gausepohl, H., M. Kraft, Ch. Boulin, and R. W. Frank. 1990. Automated multiple peptide synthesis with BOP activation. In Proceedings of the 11th American Peptide Symposium. J. E. River and G. R. Marshall, eds. ESCOM, Leiden, The Netherlands, p. 1003.
19. Tanigawa, T., M. Hikida, T. Tukai, T. Yasuda, and H. Ohmori. 1993. Enhancement of expression of an introduced gene by 5-azacytidine in mammalian cell lines. J. Ferment. Bioeng. 75:254.
20. Matsutake, T., T. Susaki, T. Ogino, M. Kaku, and E. Nakayama. 1995. Prevention of mortality by in vivo depletion of αβ T cells in in murine lethal listeriosis and involvement of γδ T cells in bacterial elimination. Immunobiology 193:71.
21. Leo, O., M. Foo, D. H. Sachs, L. E. Samelson, and J. A. Bluestone. 1987. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc. Natl. Acad. Sci. USA 84:1374.
22. Kubo, R. T., W. Born, J. W. Kappler, P. Marrack, and M. Pigeon. 1989. Characterization of a monoclonal antibody which detects all inurine αβ T cell receptors. J. Immunol. 142:2736.
23. Itohura, S., N. Nakanishi, O. Kanagawa, R. Kubo, and S. Tonegawa. 1989, Monoclonal antibodies specific to native murine T-cell receptor γδ: analysis of γδ T cells during thymic ontogeny and in peripheral lymphoid organs. Proc. Natl. Acad. Sci. USA 86:5094.
24. Dialynas, D. P., Z. S. Quan, K. A. Wall, A. Pierres, J. Quintans, M. R. Loken, M. Pierres, and F. W. Fitch. 1983. Characterization of a murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule. J. Immunol. 131:2445.
25. Nakayama, E., and A. Uenaka. 1985. Effect of in vivo administration of Lyt antibodies: Lyt phenotype of T cells in lymphoid tissues and blocking of tumor rejection. J. Exp. Med. 161:345.
26. Ozato, K., N. Mayer, and D. H. Sachs. 1980. Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens. J. Immunol. 124:533.
27. Obata, Y., Y.-T. Chen, E. Stockert, and L. J. Old. 1985. Structural analysis of TL genes of the mouse. Proc. Natl. Acad. Sci. USA 82:5475.
28. - T cell receptor αβ T cells: generation of an in vitro major histocompatibility complex class I specific cytotoxic T lymphocyte response and allogeneic tumor rejection, J. Exp. Med. 174:193.
29. - T cell receptor-αβ phenotypes generated in CD8-depleted C57BL/6 mice. J. Immunol. 150:4900.
30. Ichikawa, T., E. Nakayama, A. Uenaka, M. Monden, and T. Mori. 1987. Effector cells in allelic H-2 class I-incompatible skin graft rejection. J. Exp. Med. 166:982.
31. b antigen. J. Exp. Med. 173:261.
32. Sprent, J., M. Schaefer, D. Lo, and R. Korngold. 1986. Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences. J. Exp. Med. 163:998.
33. b mutant skin allografts differing at class I MHC. Nature 322: 829.
34. Gracie, J.-A., E. M. Bolton, C. Porteous, and J. A. Bradley. 1990. T cell requirements for the rejection of renal allografts bearing an isolated class I MHC disparity. J. Exp. Med. 172:1547.
35. + T cell and B cell responses after cardiac allograft rejection. Transplantation 59:401.
36. + cells are essential for allorejection. J. Exp. Med 184:2013.
37. Rosenberg, A. S., T. Mizuochi, S. O. Sharrow, and A. Singer. 1987. Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection. J. Exp. Med. 165:1296.
38. Keene, J.-A., and J. Forman. 1982. Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J. Exp. Med. 155:768.
39. Rammensee, H.-G., T. Friede, and S. Stevanovic. 1995. MHC ligands and peptide motifs: first listing. Immunogenetics 41:178.
40. Fangmann, J., R. Dalchau, and J. W. Fabre. 1992. Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides. J. Exp. Med. 175:1521.
41. Liu, Z., N. S. Braunstein, and N. Suciu-Foca. 1992. T cell recognition of allopeptides in context of syngeneic MHC. J. Immunol. 148:35.
42. Benichou, G., P. A. Takizawa, C. A. Olson, M. McMillan, and E. E. Sercarz. 1992. Donor major histocompatibility complex (MHC) peplides are presented by recipient MHC molecules during graft rejection. J. Exp. Med. 175:305.