Clobetasol Propionate Emollient 0.05 Percent: Hypothalamic-Pituitary-Adrenal-Axis Safety and Four-Week Clinical Efficacy Results in Plaque-Type Psoriasis

Cutis

Volumn 60, Issue 1, 1997, Pages 55-60

  Jorizzo, Joseph L ^a   Magee, Karen ^b   Stewart, Daniel M ^c   Lebwohl, Mark G ^d   Rajagopalan, Rukmini ^e   Brown, Jeanine J ^e  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c Midwest Cutaneous Research Corp   (United States)

^d MOUNT SINAI MEDICAL CENTER   (United States)

^e GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOBETASOL; DERMATOLOGICAL AGENT; DRUG DERIVATIVE; EMOLLIENT AGENT; HYDROCORTISONE;

ADULT; AGED; ARTICLE; BLOOD; CHEMICAL BURN; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG SCREENING; ECZEMA; FEMALE; FUNCTIONS OF THE SKIN AND ITS APPENDAGES; HUMAN; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; MIDDLE AGED; OUTCOME ASSESSMENT; PATHOLOGY; PATHOPHYSIOLOGY; PHASE 3 CLINICAL TRIAL; PRURITUS; PSORIASIS; RANDOMIZED CONTROLLED TRIAL; SKIN; TIME; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; BURNS, CHEMICAL; CLOBETASOL; CROSS-OVER STUDIES; DERMATOLOGIC AGENTS; DOUBLE-BLIND METHOD; DRUG EVALUATION; ECZEMA; EMOLLIENTS; FEMALE; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); PITUITARY-ADRENAL SYSTEM; PRURITUS; PSORIASIS; SKIN; SKIN PHYSIOLOGY; TIME FACTORS; TREATMENT OUTCOME;

EID: 0031181257     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (5)

1. Data on file, Glaxo Dermatology, Research Triangle Park, North Carolina.
2. Mensing H, Korsukewitz G, Yawalkar S: A double-blind, multicenter comparison between 0.05% halobetasol propionate ointment and 0.05% betamethasone dipropionate ointment in chronic plaque psoriasis. J Am Acad Dermatol 25: 1149-1152, 1991.
3. Marks R: Adverse side effects from the use of topical corticosteroids. In, Topical Corticosteroids (Maibach HI, Surber CH, eds), pp 170-183. Basel, Switzerland, S. Karger, 1992.
4. Maloney JM, Morman MR, Stewart DM, et al: Clinical efficacy and safety of clobetasol propionate emollient 0.05% in the treatment of moderate to severe atopic dermatitis. Int J Dermatol (in press).
5. Anonymous: Physicians' Desk Reference, 50th ed. Montvale, NJ, Medical Economics Data Production Company, 1996, pp 1179-1181.