Host genetic factors influencing the outcome of hepatitis

Journal of Viral Hepatitis

Volumn 4, Issue 4, 1997, Pages 215-220

  Thursz, M R ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

DRBI*1302; Hepatitis B; Hepatitis C; Major histocompatibility complex; Mannose binding protein; TNF

Indexed keywords

DISEASE PREDISPOSITION; GENETICS; HEPATITIS B; HEPATITIS C; HUMAN; IMMUNOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX; REVIEW;

DISEASE SUSCEPTIBILITY; HEPATITIS B; HEPATITIS C; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX;

EID: 0031180927     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2893.1997.00052.x     Document Type: Review

References (34)

1. Lin TM, Chen CJ, Wu MM et al. Hepatitis B virus markers in Chinese twins. Anticancer Research 1989; 9: 737-742.
2. Hann H-WL, Kim CY, London WT, Whitford P, Blumberg BS. Hepatitis B virus and primary hepatocellular carcinoma: family studies in Korea. Int J Cancer 1982; 30: 47-51.
3. London WT, Drew JS. Sex differences in response to hepatitis B infection among patients receiving chronic dialysis treatment. Proc Natl Acad Scii USA 1977; 74: 2561-2563.
4. Craxi A, Montano L, Goodall A, Thomas HC. Genetic and sex-linked factors influencing HBs antigen clearance: non-immune clearance in inbred strains of mice. J Med Virol 1982; 9: 117-121.
5. Ferrari C, Penna A, Bertoletti A et al. Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection. J Immunol 1990; 145(10): 3442-3449.
6. Thursz MR, Kwiatkowski D, Allsopp CEM, Greenwood BM, Thomas HC, Hill AVS. Association between an MHC class II allele and clearance of hepatitis B virus in The Gambia. N Engl J Med 1995; 332: 1065-1069.
7. Hohler T, Gerken G, Notghi A et al. HLA-DRBI* 1301 and 1302 protect against chronic hepatitis B. J Hepatol 1997; 26(3): 503-507.
8. Almarri A, Batchelor JR. HLA and hepatitis B infection. Lancet 1994; 344: 1194-1195.
9. Bertoletti A, Ferrari C, Fiaccador F et al. HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen. Proc Natl Acad Sci USA 1991; 88(23): 10445-10449.
10. Waters JA, O'Rourke S, Schlict HJ, Thomas HC. Cytotoxic T cell responses in patients with chronic hepatitis B virus infection undergoing HBe antigen/antibody seroconversion. Clin Exp Immunol 1995; 102: 314-319.
11. Munoz LA. Serum opsonic activity and polymorphonuclear cell function in patients with chronic liver disease. 1987; University of London: PhD thesis.
12. Summerfield JA, Ryder S, Sumiya M et al. Mannose binding protein gene mutations associated with unusual and severe infections in adults. Lancet 1995; 345: 886-890.
13. Sumiya M, Super M, Tabona P et al. Molecular basis of opsonic defect in immunodeficient children. Lancet 1991; 337: 1569-1570.
14. Gerlich WH. Structure and molecular biology. In: Zuckerman AJ, Thomas HC, eds. Viral Hepatitis. Churchill Livingstone.
15. Thomas HC, Foster GR, Sumiya M, McIntosh D, Turner MW, Summerfield JA. Mutation of gene of mannose-binding protein associated with chronic hepatitis B viral infection. Lancet 1996; 348 (9039): 1417-1419.
16. Wilson AG, deVries N, Pociot F, di Giovine FS, van der Putte LBA, Duff GW. An allelic polymorphism within the tumour necrosis alpha promoter region is strongly associated with HLA A1, B8, DR3 alleles. J Exp Med 1993; 177: 557-560.
17. Gillies PN, Fey G, Chisari FV. TNFα negatively regulates hepatitis B virus gene expression in transgenic mice. J Virol 1992; 66(6): 3955-3960.
18. Mota AH, Fainboim H, Terg R, Fainboim L. Association of chronic active hepatitis and HLA B35 in patients with hepatitis B virus. Tissue Antigens 1987; 30: 238-240.
19. van Hattum J, Schreuder GMTh, Schalm SW. HLA antigens in patients with various courses after hepatitis B virus infection. Hepatology 1987; 7(1): 11-14.
20. Giani G, Chiaramonte M, Venturi Pasini C, Fagiolo U, Naccarato R. Hepatitis B surface antigenaemia and HLA antigens. N Engl J Med 1979; 296: 1056.
21. Kruskall MS, Alper CA, Awdeh Z, Yunis EJ, Marcus-Bagley D. The immune response to hepatitis B vaccine in humans: inheritance patterns in families. J Exp Med 1992; 175(2): 495-502.
22. Hatae K, Kimura A, Okubo R et al. Genetic control of non-responsiveness to hepatitis B virus vaccine by an extended HLA haplotype. Eur J Immunol 1992; 22(7): 1899-1905.
23. Jung MC, Diepolder HM, Spengler U et al. Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection. J Virol 1995; 69(6): 3358-3368.
24. Scully L, Brown D, Lloyd C, Shein R, Thomas H. Immunological studies before and during interferon therapy in chronic HBV infection: Identification of factors predicting response. Hepatology 1990: 12: 1111-1117.
25. Daniels HM, Meager A, Eddleston AL, Alexander GJ, Williams R. Spontaneous production of tumour necrosis factor alpha and interleukin 1 beta during interferon alpha treatment of chronic HBV infection. Lancet 1990; 335: 875-877.
26. McGlynn KA, Rosvold EA, Lustbader ED et al. Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1. Proc Natl Acad Sci USA 1995; 92(6): 2384-2387.
27. Vitte RL, Fortier C, Richardet JP et al. HLA antigens in patients with chronic hepatitis C. Tissue Antigens 1995; 45: 356-361.
28. Peano G, Menardi G, Ponzetto A, Fenoglio LM. HLA-DR5 antigen. A genetic factor influencing the outcome of hepatitis C virus infection? Arch Intern Med 1994; 154(23): 2733-2736.
29. Hohler T, Gerken G, Notghi A et al. MHC class II genes influence susceptibility to chronic hepatitis C. Human Immunol 1996; 47: 123.
30. Tibbs C, Donaldson P, Underbill J, Thomson L, Manabe K, Williams R. Evidence that the HLA DQA1*03 allele confers protection from chronic HCV infection in Northern European Caucasoids. Hepatology 1996; 24(6): 1342-1345.
31. Congia M, Clemente MG, Dessi C et al. HLA class II genes in chronic hepatitis C virus-infection and associated immunological disorders. Hepatology 1996; 24(6): 1338-1341.
32. Hoffmann RM, Diepolder HM, Zachoval R et al. Mapping of immunodominant CD4+ T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection. Hepatology 1995; 21(3): 632-638.
33. Tillmann HL, Chen DF, Boker K et al. Low frequency of HLA-DR5 in patients with HCV induced end-stage liver cirrhosis requiring transplantation. Human Immunol 1996; 47: 122.
34. Brandhagen DJ, Poterucha JJ, Gross Jr JB, Gossard AA, Therneau TM, Persing DH. The effects of HLA haplotype on interferon response in patients with chronic hepatitis C. Dig Dis Wkly 1996; 282: A-71.