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Volumn 38, Issue 4 PART 2, 1997, Pages 724-731

Clinical implications of studies with MnDPDP in animal models of hepatic abnormalities

Author keywords

Contrast media, manganese; Experimental; Hepatic dysfunction, MR imaging; Liver neoplasms, cholestasis; Mangafodipir trisodium

Indexed keywords

CONTRAST MEDIUM; DIAGNOSTIC AGENT; DRUG DERIVATIVE; EDETIC ACID; MANGANESE; N,N' BIS(PYRIDOXAL 5 PHOSPHATE)ETHYLENEDIAMINE N,N' DIACETIC ACID; N,N'-BIS(PYRIDOXAL-5-PHOSPHATE)ETHYLENEDIAMINE-N,N'-DIACETIC ACID; PYRIDOXAL 5 PHOSPHATE;

EID: 0031180050     PISSN: 02841851     EISSN: None     Source Type: Journal    
DOI: 10.3109/02841859709172405     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 0026572576 scopus 로고
    • Hepatic MR imaging with Mn-DPDP. Safety, image quality, and sensitivity
    • BERNARDINO M. E., YOUNG S. W., LEE J. K. T. & WEINREB J. C.: Hepatic MR imaging with Mn-DPDP. Safety, image quality, and sensitivity. Radiology 183 (1992), 53.
    • (1992) Radiology , vol.183 , pp. 53
    • Bernardino, M.E.1    Young, S.W.2    Lee, J.K.T.3    Weinreb, J.C.4
  • 2
    • 0030210744 scopus 로고    scopus 로고
    • Uptake of mangafodipir trisodium (MnDPDP) by hepatocellular carcinoma. Correlation with unenhanced imaging findings and histopathologic features
    • CHEZMAR J., REDVANLY R. D. & SEWELL C. W.: Uptake of mangafodipir trisodium (MnDPDP) by hepatocellular carcinoma. Correlation with unenhanced imaging findings and histopathologic features. Acad. Radiol. 3 (1996), S413.
    • (1996) Acad. Radiol. , vol.3
    • Chezmar, J.1    Redvanly, R.D.2    Sewell, C.W.3
  • 4
    • 0026018467 scopus 로고
    • Preclinical evaluation of Mn-DPDP. New paramagnetic hepatobiliary contrast agent for MR imaging
    • ELIZONDO G., FRETZ C. J., STARK D. D. et al.: Preclinical evaluation of Mn-DPDP. New paramagnetic hepatobiliary contrast agent for MR imaging. Radiology 178 (1991), 73.
    • (1991) Radiology , vol.178 , pp. 73
    • Elizondo, G.1    Fretz, C.J.2    Stark, D.D.3
  • 5
    • 0028285237 scopus 로고
    • Biodistribution and in vivo stability of manganese dipyridoxyl-diphosphate in relation to imaging efficacy
    • GRANT D., HOLTZ E. & ZECH K.: Biodistribution and in vivo stability of manganese dipyridoxyl-diphosphate in relation to imaging efficacy. Invest. Radiol. 29 (1994), S249.
    • (1994) Invest. Radiol. , vol.29
    • Grant, D.1    Holtz, E.2    Zech, K.3
  • 6
    • 0031182075 scopus 로고    scopus 로고
    • Tissue distribution and general safety of MnDPDP in male beagle dogs, with or without total common bile duct obstruction
    • GRANT D., TOFT K. G., MARTINSEN I. & ATZPODIEN E.: Tissue distribution and general safety of MnDPDP in male beagle dogs, with or without total common bile duct obstruction. Acta. Radiol. 38 (1997), 732.
    • (1997) Acta. Radiol. , vol.38 , pp. 732
    • Grant, D.1    Toft, K.G.2    Martinsen, I.3    Atzpodien, E.4
  • 7
    • 0026500525 scopus 로고
    • Focal liver lesions. MR imaging with Mn-DPDP - Initial clinical results in 40 patients
    • HAMM B., VOGL T. J., BRANDING G. et al.: Focal liver lesions. MR imaging with Mn-DPDP - Initial clinical results in 40 patients. Radiology 182 (1992), 167.
    • (1992) Radiology , vol.182 , pp. 167
    • Hamm, B.1    Vogl, T.J.2    Branding, G.3
  • 8
    • 0031184555 scopus 로고    scopus 로고
    • Plasma pharmacokinetics, tissue distribution and excretion of MnDPDP in the rat and dog after intravenous administration
    • HUSTVEDT S. O., GRANT D., SOUTHON T. E. & ZECH K.: Plasma pharmacokinetics, tissue distribution and excretion of MnDPDP in the rat and dog after intravenous administration. Acta. Radiol. 38 (1997), 690.
    • (1997) Acta. Radiol. , vol.38 , pp. 690
    • Hustvedt, S.O.1    Grant, D.2    Southon, T.E.3    Zech, K.4
  • 9
    • 0016271925 scopus 로고
    • Biliary excretion of manganese in rats, rabbits and dogs
    • KLAASSEN C. D.: Biliary excretion of manganese in rats, rabbits and dogs. Toxicol. Appl. Pharmacol. 29 (1974), 458.
    • (1974) Toxicol. Appl. Pharmacol. , vol.29 , pp. 458
    • Klaassen, C.D.1
  • 10
    • 0028432361 scopus 로고
    • Enhanced tumor detection in the presence of fatty liver disease. Cell-specific contrast agents
    • KREFT B. P., TANIMOTO A., BABA Y., ZHAO L., FINN J. P. & STARK D. D.: Enhanced tumor detection in the presence of fatty liver disease. Cell-specific contrast agents. J. Magn. Reson. Imaging 4 (1994), 337.
    • (1994) J. Magn. Reson. Imaging , vol.4 , pp. 337
    • Kreft, B.P.1    Tanimoto, A.2    Baba, Y.3    Zhao, L.4    Finn, J.P.5    Stark, D.D.6
  • 11
    • 0018757484 scopus 로고
    • Dose and time relationship in manganese-bilirubin cholestasis
    • DE LAMIRANDE E. & PLAA G. L.: Dose and time relationship in manganese-bilirubin cholestasis. Toxicol. Appl. Pharmacol. 49 (1979), 257.
    • (1979) Toxicol. Appl. Pharmacol. , vol.49 , pp. 257
    • De Lamirande, E.1    Plaa, G.L.2
  • 12
    • 0018185001 scopus 로고
    • Role of manganese, bilirubin and sulfobromophtalein in manganese-bilirubin cholestasis in rats
    • DE LAMIRANDE E. & PLAA G. L.: Role of manganese, bilirubin and sulfobromophtalein in manganese-bilirubin cholestasis in rats. Proc. Soc. Exp. Biol. Med. 158 (1978), 283.
    • (1978) Proc. Soc. Exp. Biol. Med. , vol.158 , pp. 283
    • De Lamirande, E.1    Plaa, G.L.2
  • 15
    • 0027979676 scopus 로고
    • Differentiation of hepatomas from nonhepatomatous masses. Use of MnDPDP-enhanced MR images
    • LIOU J., LEE J. K. T., BORRELLO J. A. & BROWN J. J.: Differentiation of hepatomas from nonhepatomatous masses. Use of MnDPDP-enhanced MR images. Magn. Reson. Imaging 12 (1994), 71.
    • (1994) Magn. Reson. Imaging , vol.12 , pp. 71
    • Liou, J.1    Lee, J.K.T.2    Borrello, J.A.3    Brown, J.J.4
  • 17
    • 0027296346 scopus 로고
    • Comparison between Gd-DTPA, Gd-EOB-DTPa and Mn-DPDP in induced HCC in rats. a correlation study of MR imaging, microangiography and histology
    • MARCHAL G., ZHANG X., NI Y., YU J. & BAERT A.: Comparison between Gd-DTPA, Gd-EOB-DTPA and Mn-DPDP in induced HCC in rats. A correlation study of MR imaging, microangiography and histology. Magn. Reson. Imaging 11 (1993), 665.
    • (1993) Magn. Reson. Imaging , vol.11 , pp. 665
    • Marchal, G.1    Zhang, X.2    Ni, Y.3    Yu, J.4    Baert, A.5
  • 18
    • 0028858193 scopus 로고
    • A toxicologic risk for using manganese complexes? A literature survey of existing data through several medical specialties
    • MISSELWITZ B., MÜHLER A. & WEINMANN H. J.: A toxicologic risk for using manganese complexes? A literature survey of existing data through several medical specialties. Invest. Radiol. 30 (1995), 611.
    • (1995) Invest. Radiol. , vol.30 , pp. 611
    • Misselwitz, B.1    Mühler, A.2    Weinmann, H.J.3
  • 19
    • 0006419795 scopus 로고
    • Complete elimination of the hepatobiliary MR contrast agent Gd-EOB-DTPA in hepatic dysfunction. An experimental study using transport-deficient, mutant rats
    • MÜHLER A., OUDE ELFERINK R. P. J. & WEINMANN H. J.: Complete elimination of the hepatobiliary MR contrast agent Gd-EOB-DTPA in hepatic dysfunction. An experimental study using transport-deficient, mutant rats. MAGMA 1 (1993), 134.
    • (1993) MAGMA , vol.1 , pp. 134
    • Mühler, A.1    Oude Elferink, R.P.J.2    Weinmann, H.J.3
  • 20
    • 0029994023 scopus 로고    scopus 로고
    • Hepatocellular carcinoma. MR imaging with mangafodipir trisodium (Mn-DPDP)
    • MURAKAMI T., BARON R., PETERSON M. S. et al.: Hepatocellular carcinoma. MR imaging with mangafodipir trisodium (Mn-DPDP). Radiology 200 (1996), 69.
    • (1996) Radiology , vol.200 , pp. 69
    • Murakami, T.1    Baron, R.2    Peterson, M.S.3
  • 21
    • 0026784206 scopus 로고
    • MR imaging, microangiography and histology in a rat model of primary liver cancer
    • NI Y., MARCHAL G., VAN DAMME B. et al.: MR imaging, microangiography and histology in a rat model of primary liver cancer. Invest. Radiol. 27 (1992), 689.
    • (1992) Invest. Radiol. , vol.27 , pp. 689
    • Ni, Y.1    Marchal, G.2    Van Damme, B.3
  • 22
    • 0028438298 scopus 로고
    • Prolonged positive enhancement by Gd-EOB-DTPA in experimental liver tumors. Potential value in tissue characterization
    • NI Y., MARCHAL G., YU J., MÜHLER A., LUKITO G. & BAERT A. L.: Prolonged positive enhancement by Gd-EOB-DTPA in experimental liver tumors. Potential value in tissue characterization. J. Magn. Reson. Imaging 4 (1994), 355.
    • (1994) J. Magn. Reson. Imaging , vol.4 , pp. 355
    • Ni, Y.1    Marchal, G.2    Yu, J.3    Mühler, A.4    Lukito, G.5    Baert, A.L.6
  • 23
    • 0027818685 scopus 로고
    • The uptake of manganese dipyridoxal-diphosphate by chemically induced hepatocellular carcinoma in rats. A correlation between contrast-media-enhanced magnetic resonance imaging, tumor differentiation and vascularization
    • NI Y., MARCHAL G., ZHANG X. et al.: The uptake of manganese dipyridoxal-diphosphate by chemically induced hepatocellular carcinoma in rats. A correlation between contrast-media-enhanced magnetic resonance imaging, tumor differentiation and vascularization. Invest. Radiol. 28 (1993), 520.
    • (1993) Invest. Radiol. , vol.28 , pp. 520
    • Ni, Y.1    Marchal, G.2    Zhang, X.3
  • 24
    • 0029279096 scopus 로고
    • The effect of Mn-DPDP on liver MR imaging and serum bilirubin in rats with removable biliary obstruction
    • NI Y., PETRÉ C., LUKITO G. et al.: The effect of Mn-DPDP on liver MR imaging and serum bilirubin in rats with removable biliary obstruction. Acad. Radiol. 2 (1995), 300.
    • (1995) Acad. Radiol. , vol.2 , pp. 300
    • Ni, Y.1    Petré, C.2    Lukito, G.3
  • 25
    • 0028113914 scopus 로고
    • Potential role of bile duct collaterals in the recovery of the biliary obstruction. Experimental study in rats with microcholangiography, histology, serology and magnetic resonance imaging
    • NI Y., LUKITO G., MARCHAL G. et al.: Potential role of bile duct collaterals in the recovery of the biliary obstruction. Experimental study in rats with microcholangiography, histology, serology and magnetic resonance imaging. Hepatology 20 (1994), 1557.
    • (1994) Hepatology , vol.20 , pp. 1557
    • Ni, Y.1    Lukito, G.2    Marchal, G.3
  • 26
    • 0027160584 scopus 로고
    • Experimental liver cancers. Mn-DPDP-enhanced rims in MR-microangiographic-histologic correlation study
    • NI Y., MARCHAL G., YU J. et al.: Experimental liver cancers. Mn-DPDP-enhanced rims in MR-microangiographic-histologic correlation study. Radiology 188 (1993), 45.
    • (1993) Radiology , vol.188 , pp. 45
    • Ni, Y.1    Marchal, G.2    Yu, J.3
  • 28
    • 0001309141 scopus 로고
    • Manganese (II) N, N′-dipyridoxylethylen-ediamine-NN′-diacetate 5,5′-bis (phosphate). Synthesis and characterization of a paramagnetic chelate for magnetic resonance imaging enhancement
    • ROCKLAGE S. M., CAAHERIS W. P., QUAY S. C., HAHN F. E. & RAYMOND K. N.: Manganese (II) N, N′-dipyridoxylethylen-ediamine-NN′-diacetate 5,5′-bis (phosphate). Synthesis and characterization of a paramagnetic chelate for magnetic resonance imaging enhancement. Inorg. Chem. 28 (1989). 477.
    • (1989) Inorg. Chem. , vol.28 , pp. 477
    • Rocklage, S.M.1    Caaheris, W.P.2    Quay, S.C.3    Hahn, F.E.4    Raymond, K.N.5
  • 29
    • 0346821631 scopus 로고
    • Hepatobiliary contrast agents. An overview of the development of manganese dipyridoxyl diphosphate (MnDPDP)
    • Edited by J. T. Ferrucci & D. D. Stark. Andover Medical, Boston
    • ROCKLAGE S. M. & VANWAGONER M.: Hepatobiliary contrast agents. An overview of the development of manganese dipyridoxyl diphosphate (MnDPDP). In: Liver imaging, p. 374. Edited by J. T. Ferrucci & D. D. Stark. Andover Medical, Boston 1990.
    • (1990) Liver Imaging , pp. 374
    • Rocklage, S.M.1    Vanwagoner, M.2
  • 31
    • 0025838385 scopus 로고
    • Manganese-DPDP as a hepatobiliary contrast agent in the magnetic resonance imaging of liver tumors. Results of clinical phase II trials in Germany including 141 patients
    • RUMMENY E., EHRENHEIM C., GEHL H. B. et al.: Manganese-DPDP as a hepatobiliary contrast agent in the magnetic resonance imaging of liver tumors. Results of clinical phase II trials in Germany including 141 patients. Invest. Radiol. 26 (1991), S142.
    • (1991) Invest. Radiol. , vol.26
    • Rummeny, E.1    Ehrenheim, C.2    Gehl, H.B.3
  • 32
    • 0002447917 scopus 로고
    • Value of delayed Mn-DPDP enhanced MR imaging in the detection and differential diagnosis of hepatic tumors
    • RUMMENY E., WIESMANN W., MENKER S., LODEMANN K. & PETER P. E.: Value of delayed Mn-DPDP enhanced MR imaging in the detection and differential diagnosis of hepatic tumors. J. Magn. Reson. Imaging 2 (1992), 65.
    • (1992) J. Magn. Reson. Imaging , vol.2 , pp. 65
    • Rummeny, E.1    Wiesmann, W.2    Menker, S.3    Lodemann, K.4    Peter, P.E.5
  • 33
    • 0000702437 scopus 로고
    • Manganese
    • chapter 15, Edited by L. Firebug et al. Elsevier Science Publishers B.V., Amsterdam
    • SARIC M.: Manganese. In: Handbook on the toxicology of metals, vol. 2, chapter 15, p. 354. Edited by L. Firebug et al. Elsevier Science Publishers B.V., Amsterdam 1986.
    • (1986) Handbook on the Toxicology of Metals , vol.2 , pp. 354
    • Saric, M.1
  • 34
    • 0027819162 scopus 로고
    • Manganese dipyridoxal diphosphate-enhanced magnetic resonance imaging in the evaluation of hepatocyte function
    • SIDHU M. K., MULLER H. H., AGGELER J., JONES A. L. & YOUNG S. W.: Manganese dipyridoxal diphosphate-enhanced magnetic resonance imaging in the evaluation of hepatocyte function. Invest. Radiol. 28 (1993), 903.
    • (1993) Invest. Radiol. , vol.28 , pp. 903
    • Sidhu, M.K.1    Muller, H.H.2    Aggeler, J.3    Jones, A.L.4    Young, S.W.5
  • 36
    • 0027668769 scopus 로고
    • Evaluation of hepatocyte-specific paramagnetic contrast media for MR imaging of hepatitis
    • TANIMOTO A., KREFT B. P., BABA Y. et al.: Evaluation of hepatocyte-specific paramagnetic contrast media for MR imaging of hepatitis. J. Magn. Reson. Imaging 3 (1993), 786.
    • (1993) J. Magn. Reson. Imaging , vol.3 , pp. 786
    • Tanimoto, A.1    Kreft, B.P.2    Baba, Y.3
  • 37
    • 0031182136 scopus 로고    scopus 로고
    • Metabolism and pharmacokinetics of MnDPDP in man
    • TOFT K. G., HUSTVEDT S. O., GRANT D. et al.: Metabolism and pharmacokinetics of MnDPDP in man. Acta Radiol. 38 (1997), 677.
    • (1997) Acta Radiol. , vol.38 , pp. 677
    • Toft, K.G.1    Hustvedt, S.O.2    Grant, D.3
  • 40
    • 0015011932 scopus 로고
    • Bilirubin as a cholestatic agent. Physiologic and morphologic observations
    • WITZLEBEN C. L.: Bilirubin as a cholestatic agent. Physiologic and morphologic observations. Am. J. Pathol. 62 (1971), 181.
    • (1971) Am. J. Pathol. , vol.62 , pp. 181
    • Witzleben, C.L.1
  • 42
    • 0024582714 scopus 로고
    • MRI measurement of hepatocyte toxicity using the new MRI contrast agent manganese dipyridoxal diphosphate, a manganese/pyridoxal-5-phosphate chelate
    • YOUNG S. W., SIMPSON B. B., RATNER A. V., MATKIN C. & CARTER E.: MRI measurement of hepatocyte toxicity using the new MRI contrast agent manganese dipyridoxal diphosphate, a manganese/pyridoxal-5-phosphate chelate. Magn. Reson. Med. 10 (1989), 1.
    • (1989) Magn. Reson. Med. , vol.10 , pp. 1
    • Young, S.W.1    Simpson, B.B.2    Ratner, A.V.3    Matkin, C.4    Carter, E.5


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