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Volumn 65, Issue 4, 1997, Pages 339-354

Clinical use of hematopoietic growth factors in patients with myelodysplastic syndromes

Author keywords

Cytokines; Erythropoietin; G CSF; IL 3; Myelodysplastic syndromes

Indexed keywords

CYTARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOGLOBIN; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 3; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT INTERLEUKIN 6; RETINOIC ACID; THROMBOPOIETIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0031172780     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0925-5710(96)00562-2     Document Type: Review
Times cited : (14)

References (161)
  • 1
    • 0026665815 scopus 로고
    • Clinical course of myelodysplastic syndromes
    • [1] Ganser A, Hoelzer D. Clinical course of myelodysplastic syndromes. Hematol/Oncol Clin North Am 1992;6:607-618.
    • (1992) Hematol/Oncol Clin North Am , vol.6 , pp. 607-618
    • Ganser, A.1    Hoelzer, D.2
  • 2
    • 0021192215 scopus 로고
    • 'Atypical' leukemias: Preleukemia, smoldering leukemia and hypoplastic leukemia
    • [2] Hoelzer D, Ganser A, Heimpel H. 'Atypical' leukemias: preleukemia, smoldering leukemia and hypoplastic leukemia. Rec Res Cancer Res 1984;93:69-101.
    • (1984) Rec Res Cancer Res , vol.93 , pp. 69-101
    • Hoelzer, D.1    Ganser, A.2    Heimpel, H.3
  • 3
    • 0019952276 scopus 로고
    • Proposals for the classification of the myelodysplastic syndromes
    • [3] Bennett JM, Catovsky D, Daniel M et al. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 1982;51:189-199.
    • (1982) Br J Haematol , vol.51 , pp. 189-199
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.3
  • 4
    • 0023096812 scopus 로고
    • Histopathology and myelodysplastic syndromes: The FAB classification (proposals) applied to bone marrow biopsy
    • [4] Delacretaz F, Schmidt PM, Piguet D et al. Histopathology and myelodysplastic syndromes: the FAB classification (proposals) applied to bone marrow biopsy. Am J Clin Pathol 1987;87:180-189.
    • (1987) Am J Clin Pathol , vol.87 , pp. 180-189
    • Delacretaz, F.1    Schmidt, P.M.2    Piguet, D.3
  • 6
    • 0026704814 scopus 로고
    • Molecular genetic aspects of myelodysplastic syndromes
    • [6] Bartram CR. Molecular genetic aspects of myelodysplastic syndromes. Hematol/Oncol Clin North Am 1992;6:557-570.
    • (1992) Hematol/Oncol Clin North Am , vol.6 , pp. 557-570
    • Bartram, C.R.1
  • 7
    • 0026148503 scopus 로고
    • Genetic lesions in preleukemia
    • [7] Jacobs A. Genetic lesions in preleukemia. Leukemia 1991;5:277-282.
    • (1991) Leukemia , vol.5 , pp. 277-282
    • Jacobs, A.1
  • 8
    • 0018138805 scopus 로고
    • A common progenitor for myeloid and lymphoid cells
    • [8] Prchal JT, Trockmorton DW, Carrol AJ et al. A common progenitor for myeloid and lymphoid cells. Nature 1978;274:590-591.
    • (1978) Nature , vol.274 , pp. 590-591
    • Prchal, J.T.1    Trockmorton, D.W.2    Carrol, A.J.3
  • 9
    • 0029020851 scopus 로고
    • Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes
    • [9] Raza A, Gezer S, Mundle S et al. Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes. Blood 1995;86:268-276.
    • (1995) Blood , vol.86 , pp. 268-276
    • Raza, A.1    Gezer, S.2    Mundle, S.3
  • 10
    • 0028930939 scopus 로고
    • Simultaneous assessment of cell kinetics and programmed cell death in bone marrow biopsies of myelodysplastics reveals extensive apoptosis as the probable basis for ineffective hematopoiesis
    • [10] Raza A, Mundle S, Iftikhar A et al. Simultaneous assessment of cell kinetics and programmed cell death in bone marrow biopsies of myelodysplastics reveals extensive apoptosis as the probable basis for ineffective hematopoiesis. Am J Hematol 1995;48:143-154.
    • (1995) Am J Hematol , vol.48 , pp. 143-154
    • Raza, A.1    Mundle, S.2    Iftikhar, A.3
  • 11
    • 0029126331 scopus 로고
    • Two karyotypically unrelated clones with 5q-and 20q-in a primary myelodysplastic syndrome patient evolving into acute nonlymphocytic leukemia
    • [11] Hirokawa M, Miura I, Miura AB. Two karyotypically unrelated clones with 5q-and 20q-in a primary myelodysplastic syndrome patient evolving into acute nonlymphocytic leukemia. Int J Hematol 1995;62:121-125.
    • (1995) Int J Hematol , vol.62 , pp. 121-125
    • Hirokawa, M.1    Miura, I.2    Miura, A.B.3
  • 12
    • 0028869121 scopus 로고
    • Cytogenetic clonality analysis in myelodysplastic syndrome: Monosomy 7 can be demonstrated in the myeloid and in the lymphoid lineage
    • [12] Van Lom K, Hagemeijer A, Smit E, Hahlen K, Groeneveld K, Löwenberg B. Cytogenetic clonality analysis in myelodysplastic syndrome: monosomy 7 can be demonstrated in the myeloid and in the lymphoid lineage. Leukemia 1995;9:1818-1821.
    • (1995) Leukemia , vol.9 , pp. 1818-1821
    • Van Lom, K.1    Hagemeijer, A.2    Smit, E.3    Hahlen, K.4    Groeneveld, K.5    Löwenberg, B.6
  • 14
    • 9044229714 scopus 로고    scopus 로고
    • Morphologic, immunologic, and cytogenetic classification of acute myeloid leukemia and myelodysplastic syndrome in childhood: A report from the Children Cancer Group
    • [14] Barnard DR, Kalousek DK, Wiersma SR et al. Morphologic, immunologic, and cytogenetic classification of acute myeloid leukemia and myelodysplastic syndrome in childhood: a report from the Children Cancer Group. Leukemia 1996;10:5-12.
    • (1996) Leukemia , vol.10 , pp. 5-12
    • Barnard, D.R.1    Kalousek, D.K.2    Wiersma, S.R.3
  • 15
    • 0024410652 scopus 로고
    • Effect of tumor necrosis factor-alpha on human hematopoietic progenitor cells
    • [15] Völkers B, Ganser A, Greher J et al. Effect of tumor necrosis factor-alpha on human hematopoietic progenitor cells. Onkologie 1989;12:109-115.
    • (1989) Onkologie , vol.12 , pp. 109-115
    • Völkers, B.1    Ganser, A.2    Greher, J.3
  • 16
    • 0027086859 scopus 로고
    • Measurement of serum cytokine levels in patients with myelodysplastic syndromes
    • [16] Verhoef GE, De Schouwer P, Ceuppens JL et al. Measurement of serum cytokine levels in patients with myelodysplastic syndromes. Leukemia 1992;6:1268-1272.
    • (1992) Leukemia , vol.6 , pp. 1268-1272
    • Verhoef, G.E.1    De Schouwer, P.2    Ceuppens, J.L.3
  • 17
    • 4243577371 scopus 로고
    • Impaired erythropoiesis in myelodysplastic syndrome is associated with the inability of erythropoietin receptor to activate STAT-5
    • [17] Hoefsloot LH, van Amelsvoort MP, Broeders CCAM et al. Impaired erythropoiesis in myelodysplastic syndrome is associated with the inability of erythropoietin receptor to activate STAT-5. Blood 1995;86(Suppl 1):271A.
    • (1995) Blood , vol.86 , Issue.SUPPL. 1
    • Hoefsloot, L.H.1    Van Amelsvoort, M.P.2    Broeders, C.C.A.M.3
  • 18
    • 0025781542 scopus 로고
    • Serum erythropoietin concentrations in patients with myelodysplastic syndromes
    • [18] Aul C, Arning M, Runde V, Schneider W. Serum erythropoietin concentrations in patients with myelodysplastic syndromes. Leuk Res 1991;15:571-575.
    • (1991) Leuk Res , vol.15 , pp. 571-575
    • Aul, C.1    Arning, M.2    Runde, V.3    Schneider, W.4
  • 19
    • 0025218074 scopus 로고
    • Serum erythropoietin and erythropoiesis in patients with myelodysplastic syndromes
    • [19] Bowen DT, Jacobs A, Cotes MP et al. Serum erythropoietin and erythropoiesis in patients with myelodysplastic syndromes. Eur J Haematol 1990;44:30-32.
    • (1990) Eur J Haematol , vol.44 , pp. 30-32
    • Bowen, D.T.1    Jacobs, A.2    Cotes, M.P.3
  • 20
    • 0024448197 scopus 로고
    • Circulating erythropoietin in patients with myelodysplastic syndromes
    • [20] Jacobs A, Janowska-Wieczorek A, Caro J et al. Circulating erythropoietin in patients with myelodysplastic syndromes. Br J Haematol 1989;73:36-39.
    • (1989) Br J Haematol , vol.73 , pp. 36-39
    • Jacobs, A.1    Janowska-Wieczorek, A.2    Caro, J.3
  • 21
    • 0026688084 scopus 로고
    • Age-related incidence and other epidemiological aspects of myelodysplastic syndromes
    • [21] Aul C, Gattermann N, Schneider W. Age-related incidence and other epidemiological aspects of myelodysplastic syndromes. Br J Haematol 1992;82:358-367.
    • (1992) Br J Haematol , vol.82 , pp. 358-367
    • Aul, C.1    Gattermann, N.2    Schneider, W.3
  • 22
    • 0019431593 scopus 로고
    • Preleukemia in children
    • [22] Blank J, Lange B. Preleukemia in children. J Pediatr 1981;98:565-569.
    • (1981) J Pediatr , vol.98 , pp. 565-569
    • Blank, J.1    Lange, B.2
  • 23
    • 0028145022 scopus 로고
    • Establishing the incidence of myelodysplastic syndrome
    • [23] Williamson PJ, Kruger AR, Reynolds PJ et al. Establishing the incidence of myelodysplastic syndrome. Br J Haematol 1994;87:743-745.
    • (1994) Br J Haematol , vol.87 , pp. 743-745
    • Williamson, P.J.1    Kruger, A.R.2    Reynolds, P.J.3
  • 24
    • 0022804866 scopus 로고
    • Myelodysplastic syndromes. Natural history and features of prognostic significance
    • [24] Mufti GJ, Galton DAG. Myelodysplastic syndromes. Natural history and features of prognostic significance. Clin Haematol 1986;15:953-978.
    • (1986) Clin Haematol , vol.15 , pp. 953-978
    • Mufti, G.J.1    Galton, D.A.G.2
  • 25
    • 0020629536 scopus 로고
    • Blood neutrophil function in primary myelodysplastic syndromes
    • [25] Boogaerts MA. Nelissen V, Roelant C, Goossens W. Blood neutrophil function in primary myelodysplastic syndromes. Br J Haematol 1983;55:217-223.
    • (1983) Br J Haematol , vol.55 , pp. 217-223
    • Boogaerts, M.A.1    Nelissen, V.2    Roelant, C.3    Goossens, W.4
  • 27
    • 0001032498 scopus 로고
    • Myelodysplastic syndromes. A prognostic factor analysis of 221 untreated patients
    • [27] Aul C, Schneider W. Myelodysplastic syndromes. A prognostic factor analysis of 221 untreated patients. Blut 1983;57:234-241.
    • (1983) Blut , vol.57 , pp. 234-241
    • Aul, C.1    Schneider, W.2
  • 28
    • 0023089077 scopus 로고
    • Utility of the FAB classification for myelodysplastic syndromes. Investigation of prognostic factors in 237 cases
    • [28] Kerkhofs H, Hermans I, Haak HL, Leeksma CHW. Utility of the FAB classification for myelodysplastic syndromes. Investigation of prognostic factors in 237 cases. Br J Haematol 1987;65:73-81.
    • (1987) Br J Haematol , vol.65 , pp. 73-81
    • Kerkhofs, H.1    Hermans, I.2    Haak, H.L.3    Leeksma, C.H.W.4
  • 29
    • 0021988836 scopus 로고
    • Myelodysplastic syndromes. A scoring system with prognostic significance
    • [29] Mufti GJ, Stevens JR, Oscier DG et al. Myelodysplastic syndromes. A scoring system with prognostic significance. Br J Haematol 1985;59:425-431.
    • (1985) Br J Haematol , vol.59 , pp. 425-431
    • Mufti, G.J.1    Stevens, J.R.2    Oscier, D.G.3
  • 30
    • 0024402407 scopus 로고
    • Two regression models and a scoring system for predicting survival and planning treatment in myelodysplastic syndromes. A multivariate analysis of prognostic factors in 370 patients
    • [30] Sanz GF, Sanz MA, Vallespi T et al. Two regression models and a scoring system for predicting survival and planning treatment in myelodysplastic syndromes. A multivariate analysis of prognostic factors in 370 patients. Blood 1989;74:395-402.
    • (1989) Blood , vol.74 , pp. 395-402
    • Sanz, G.F.1    Sanz, M.A.2    Vallespi, T.3
  • 31
    • 0021854535 scopus 로고
    • Prognostic factors in the myelodysplastic syndromes. Importance of initial data on peripheral blood counts, bone marrow cytology, trephine biopsy and chromosomal analysis
    • [31] Tricot G, Vlietinck R, Boogaerts MA et al. Prognostic factors in the myelodysplastic syndromes. Importance of initial data on peripheral blood counts, bone marrow cytology, trephine biopsy and chromosomal analysis. Br J Haematol 1985;60:19-22.
    • (1985) Br J Haematol , vol.60 , pp. 19-22
    • Tricot, G.1    Vlietinck, R.2    Boogaerts, M.A.3
  • 32
    • 0021917122 scopus 로고
    • Modifications in the classification of primary myelodysplastic syndromes. The addition of a scoring system
    • [32] Varela GL, Chuang C, Woll JE, Bennett JM. Modifications in the classification of primary myelodysplastic syndromes. The addition of a scoring system. Haematol Oncol 1985;3:55-60.
    • (1985) Haematol Oncol , vol.3 , pp. 55-60
    • Varela, G.L.1    Chuang, C.2    Woll, J.E.3    Bennett, J.M.4
  • 33
    • 0024571720 scopus 로고
    • Recombinant human granulocyte-macrophage colony-stimulating factor and low-dose cytosine arabinoside in patients with myelodysplastic syndrome. A pilot study
    • [33] Ganser A, Ottmann OG, Schulz G et al. Recombinant human granulocyte-macrophage colony-stimulating factor and low-dose cytosine arabinoside in patients with myelodysplastic syndrome. A pilot study. Onkologie 1989;12:13-15.
    • (1989) Onkologie , vol.12 , pp. 13-15
    • Ganser, A.1    Ottmann, O.G.2    Schulz, G.3
  • 34
    • 0026594343 scopus 로고
    • Treatment of myelodysplastic syndromes with cytokines and cytotoxic drugs
    • [34] Ganser A, Seipelt G, Eder M et al. Treatment of myelodysplastic syndromes with cytokines and cytotoxic drugs. Semin Oncol 1992;19(Suppl 4):95-101.
    • (1992) Semin Oncol , vol.19 , Issue.SUPPL. 4 , pp. 95-101
    • Ganser, A.1    Seipelt, G.2    Eder, M.3
  • 35
    • 0027447158 scopus 로고
    • Aggressive chemotherapy combined with G-CSF and maintenance therapy with interleukin-2 for patients with advanced myelodysplastic syndrome, subacute or secondary acute myeloid leukemia - Initial results
    • [35] Ganser A, Heil G, Kolbe K et al. Aggressive chemotherapy combined with G-CSF and maintenance therapy with interleukin-2 for patients with advanced myelodysplastic syndrome, subacute or secondary acute myeloid leukemia - initial results. Ann Hematol 1993;66:123-125.
    • (1993) Ann Hematol , vol.66 , pp. 123-125
    • Ganser, A.1    Heil, G.2    Kolbe, K.3
  • 36
    • 0028316289 scopus 로고
    • Effect of combination therapy with all-trans retinoic acid and recombinant human granulocyte colony-stimulating factor in patients with myelodysplastic syndromes
    • [36] Ganser A, Seipelt G, Verbeeck W et al. Effect of combination therapy with all-trans retinoic acid and recombinant human granulocyte colony-stimulating factor in patients with myelodysplastic syndromes. Leukemia 1994;8:369-375.
    • (1994) Leukemia , vol.8 , pp. 369-375
    • Ganser, A.1    Seipelt, G.2    Verbeeck, W.3
  • 37
    • 0029865715 scopus 로고    scopus 로고
    • Improved multilineage response of hematopoiesis in patients with myelodysplastic syndromes to a combination therapy with all-trans-retinoic acid, granulocyte colony-stimulating factor, erythropoietin, and x-tocopherol
    • [37] Ganser A, Maurer A, Contzen C et al. Improved multilineage response of hematopoiesis in patients with myelodysplastic syndromes to a combination therapy with all-trans-retinoic acid, granulocyte colony-stimulating factor, erythropoietin, and x-tocopherol. Ann Hematol 1996;72:237-244.
    • (1996) Ann Hematol , vol.72 , pp. 237-244
    • Ganser, A.1    Maurer, A.2    Contzen, C.3
  • 38
    • 0026754254 scopus 로고
    • Intensive chemotherapy and bone marrow transplantation for myelodysplastic syndromes
    • [38] Löffler H, Schmilz N, Gassmann W. Intensive chemotherapy and bone marrow transplantation for myelodysplastic syndromes. Hematol/Oncol Clin North Am 1992;6:619-632.
    • (1992) Hematol/Oncol Clin North Am , vol.6 , pp. 619-632
    • Löffler, H.1    Schmilz, N.2    Gassmann, W.3
  • 40
    • 0028789739 scopus 로고
    • Idarubicin in combination with cytarabine and VP-16 in the treatment of post myelodysplastic syndrome acute myeloblastic leukemia (MDS-AML)
    • [40] Pogliani EM, Baldicchi L, Pioltelli P, Miccolis IR, Mangiagalli M, Corneo GM. Idarubicin in combination with cytarabine and VP-16 in the treatment of post myelodysplastic syndrome acute myeloblastic leukemia (MDS-AML). Leuk Lymphoma 1995;19:473-477.
    • (1995) Leuk Lymphoma , vol.19 , pp. 473-477
    • Pogliani, E.M.1    Baldicchi, L.2    Pioltelli, P.3    Miccolis, I.R.4    Mangiagalli, M.5    Corneo, G.M.6
  • 41
    • 0027162443 scopus 로고
    • Allogeneic bone marrow transplantation for 93 patients with myelodysplastic syndrome
    • [41] Anderson JE, Appelbaum FR, Fisher LD et al. Allogeneic bone marrow transplantation for 93 patients with myelodysplastic syndrome. Blood 1993;82:677-681.
    • (1993) Blood , vol.82 , pp. 677-681
    • Anderson, J.E.1    Appelbaum, F.R.2    Fisher, L.D.3
  • 42
    • 0030069853 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation for myelodysplastic syndrome with advanced disease morphology: A phase II study of busulfan, cyclophosphamide, and total-body irradiation and analysis of prognostic factors
    • [42] Anderson JE, Appelbaum FR, Schoch G et al. Allogeneic bone marrow transplantation for myelodysplastic syndrome with advanced disease morphology: a phase II study of busulfan, cyclophosphamide, and total-body irradiation and analysis of prognostic factors. J Clin Oncol 1996;14:220-226.
    • (1996) J Clin Oncol , vol.14 , pp. 220-226
    • Anderson, J.E.1    Appelbaum, F.R.2    Schoch, G.3
  • 43
    • 0028036887 scopus 로고
    • Hematopoietic growth factors and the treatment of tumor-associated anemias
    • [43] Dührsen U, Hossfeld D. Hematopoietic growth factors and the treatment of tumor-associated anemias. Ann Hematol 1994;69:213-221.
    • (1994) Ann Hematol , vol.69 , pp. 213-221
    • Dührsen, U.1    Hossfeld, D.2
  • 44
    • 0026637152 scopus 로고
    • Treatment of myelodysplastic syndromes with hematopoietic growth factors
    • [44] Ganser A, Hoelzer D. Treatment of myelodysplastic syndromes with hematopoietic growth factors. Hematol/ Oncol Clin North Am 1992;6:633-654.
    • (1992) Hematol/ Oncol Clin North Am , vol.6 , pp. 633-654
    • Ganser, A.1    Hoelzer, D.2
  • 45
    • 0029294859 scopus 로고
    • Hematopoietic growth factors in the treatment of myelodysplastic syndromes
    • [45] Ganser A. Hematopoietic growth factors in the treatment of myelodysplastic syndromes. Curr Opin Hematol 1995;2:204-209.
    • (1995) Curr Opin Hematol , vol.2 , pp. 204-209
    • Ganser, A.1
  • 47
    • 0027448223 scopus 로고
    • Hematopoietic growth factors and their receptors in acute leukemia
    • [47] Löwenberg B, Touw IP. Hematopoietic growth factors and their receptors in acute leukemia. Blood 1993;81:281-292.
    • (1993) Blood , vol.81 , pp. 281-292
    • Löwenberg, B.1    Touw, I.P.2
  • 48
    • 0025370701 scopus 로고
    • Maintenance therapy of patients with myelodysplastic syndromes using recombinant human granulocyte colony stimulating factor
    • [48] Negrin RS, Haeuber DH, Nagler A et al. Maintenance therapy of patients with myelodysplastic syndromes using recombinant human granulocyte colony stimulating factor. Blood 1990;76:36-43.
    • (1990) Blood , vol.76 , pp. 36-43
    • Negrin, R.S.1    Haeuber, D.H.2    Nagler, A.3
  • 49
    • 0024497887 scopus 로고
    • Treatment of myelodysplastic syndromes with human granulocyte colony-stimulating factor: A preliminary report
    • [49] Kobayashi Y, Okabe T, Ozawa K et al. Treatment of myelodysplastic syndromes with human granulocyte colony-stimulating factor: a preliminary report. Am J Med 1989;86:178-182.
    • (1989) Am J Med , vol.86 , pp. 178-182
    • Kobayashi, Y.1    Okabe, T.2    Ozawa, K.3
  • 50
    • 0024352258 scopus 로고
    • Treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor. A phase I/II trial
    • [50] Negrin R, Haeuber DH, Nagler A et al. Treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor. A phase I/II trial. Ann Intern Med 1989;110:976-984.
    • (1989) Ann Intern Med , vol.110 , pp. 976-984
    • Negrin, R.1    Haeuber, D.H.2    Nagler, A.3
  • 51
    • 0023201009 scopus 로고
    • Recombinant human granulocyte colony stimulating factor repairs the abnormalities of neutrophils in patients with myelodysplastic syndromes and chronic myelogenous leukemia
    • [51] Yuo A, Kitagawa S, Okabe T et al. Recombinant human granulocyte colony stimulating factor repairs the abnormalities of neutrophils in patients with myelodysplastic syndromes and chronic myelogenous leukemia. Blood 1987;70:404-411.
    • (1987) Blood , vol.70 , pp. 404-411
    • Yuo, A.1    Kitagawa, S.2    Okabe, T.3
  • 52
    • 0025161459 scopus 로고
    • Effects of prolonged treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor
    • [52] Greenberg P, Negrin R, Nagler A et al. Effects of prolonged treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor. Int J Cell Cloning 1990;8(Suppl 1):293-302.
    • (1990) Int J Cell Cloning , vol.8 , Issue.SUPPL. 1 , pp. 293-302
    • Greenberg, P.1    Negrin, R.2    Nagler, A.3
  • 53
    • 0027304592 scopus 로고
    • Treatment of the anemia of myelodysplastic syndromes using recombinant human granulocyte colony stimulating factor in combination with erythropoietin
    • [53] Negrin RS, Stein R, Vardiman J et al. Treatment of the anemia of myelodysplastic syndromes using recombinant human granulocyte colony stimulating factor in combination with erythropoietin. Blood 1993;82:737-743.
    • (1993) Blood , vol.82 , pp. 737-743
    • Negrin, R.S.1    Stein, R.2    Vardiman, J.3
  • 54
    • 0025764755 scopus 로고
    • A phase II trial of recombinant human granulocyte colony-stimulating factor in the myelodysplastic syndromes
    • [54] Yoshida Y, Hirashima K, Asano S et al. A phase II trial of recombinant human granulocyte colony-stimulating factor in the myelodysplastic syndromes. Br J Haematol 1991;78:378-384.
    • (1991) Br J Haematol , vol.78 , pp. 378-384
    • Yoshida, Y.1    Hirashima, K.2    Asano, S.3
  • 55
    • 0000399876 scopus 로고
    • Phase III randomized multicenter trial of G-CSF vs. observation for myelodysplastic syndromes (MDS)
    • [55] Greenberg P, Taylor K, Larson R et al. Phase III randomized multicenter trial of G-CSF vs. observation for myelodysplastic syndromes (MDS). Blood 1993;82(Suppl 1):196a.
    • (1993) Blood , vol.82 , Issue.SUPPL. 1
    • Greenberg, P.1    Taylor, K.2    Larson, R.3
  • 56
    • 0027330961 scopus 로고
    • All-trans retinoic acid in patients with myelodysplastic syndromes: Results of a pilot study
    • [56] Aul C, Runde V, Gattermann N. All-trans retinoic acid in patients with myelodysplastic syndromes: results of a pilot study. Blood 1993;82:1967-1974.
    • (1993) Blood , vol.82 , pp. 1967-1974
    • Aul, C.1    Runde, V.2    Gattermann, N.3
  • 57
    • 0027227770 scopus 로고
    • All-trans retinoic acid: Tolerance and biologic effects in myelodysplastic syndromes
    • [57] Kurzrock R, Estey E, Talpaz M. All-trans retinoic acid: tolerance and biologic effects in myelodysplastic syndromes. J Clin Oncol 1993;11:1489-1496.
    • (1993) J Clin Oncol , vol.11 , pp. 1489-1496
    • Kurzrock, R.1    Estey, E.2    Talpaz, M.3
  • 58
    • 0027409244 scopus 로고
    • Treatment of myelodysplastic syndromes with all-trans retinoic acid
    • [58] Ohno R, Naoe T, Hirano M et al. Treatment of myelodysplastic syndromes with all-trans retinoic acid. Blood 1993;81:1152-1154.
    • (1993) Blood , vol.81 , pp. 1152-1154
    • Ohno, R.1    Naoe, T.2    Hirano, M.3
  • 59
    • 0026683419 scopus 로고
    • All-trans retinoic acid improves erythropoiesis in myelodysplastic syndromes: A case report
    • [59] Visani G, Cenacchi A, Tosi P et al. All-trans retinoic acid improves erythropoiesis in myelodysplastic syndromes: a case report. Br J Haematol 1992;81:444-448.
    • (1992) Br J Haematol , vol.81 , pp. 444-448
    • Visani, G.1    Cenacchi, A.2    Tosi, P.3
  • 60
    • 0028949083 scopus 로고
    • Changes in erythroid progenitor cell and accessory cell compartments in patients with myelodysplastic syndromes during treatment with all-trans retinoic acid and haematopoietic growth factors
    • [60] Maurer AB, Ganser A, Seipelt G et al. Changes in erythroid progenitor cell and accessory cell compartments in patients with myelodysplastic syndromes during treatment with all-trans retinoic acid and haematopoietic growth factors. Br J Haematol 1995;89:449-456.
    • (1995) Br J Haematol , vol.89 , pp. 449-456
    • Maurer, A.B.1    Ganser, A.2    Seipelt, G.3
  • 61
    • 0025804122 scopus 로고
    • Effects of low doses of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with myelodysplastic syndromes
    • [61] Estey EH, Kurzrock R, Talpaz M et al. Effects of low doses of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with myelodysplastic syndromes. Br J Haematol 1991;77:291-295.
    • (1991) Br J Haematol , vol.77 , pp. 291-295
    • Estey, E.H.1    Kurzrock, R.2    Talpaz, M.3
  • 62
    • 0025910278 scopus 로고
    • Differential dose-related haematological effects of GM-CSF in pancytopenia: Evidence supporting the advantage of lowover high-dose administration in selected patients
    • [62] Kurzrock R, Talpaz M, Gomez JA et al. Differential dose-related haematological effects of GM-CSF in pancytopenia: evidence supporting the advantage of lowover high-dose administration in selected patients. Br J Haematol 1991;78:352-358.
    • (1991) Br J Haematol , vol.78 , pp. 352-358
    • Kurzrock, R.1    Talpaz, M.2    Gomez, J.A.3
  • 63
    • 0027978962 scopus 로고
    • Treatment with very low-dose GM-CSF in myelodysplastic syndromes with neutropenia. A report on 28 cases
    • [63] Rose C, Wattel E, Bastion Y et al. Treatment with very low-dose GM-CSF in myelodysplastic syndromes with neutropenia. A report on 28 cases. Leukemia 1994;8:1458-1462.
    • (1994) Leukemia , vol.8 , pp. 1458-1462
    • Rose, C.1    Wattel, E.2    Bastion, Y.3
  • 64
    • 0000225805 scopus 로고
    • Randomized phase II study of recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) in patients with neutropenia secondary to myelodysplastic syndrome (MDS)
    • [64] Schuster MW, Thompson JA, Larson R et al. Randomized phase II study of recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) in patients with neutropenia secondary to myelodysplastic syndrome (MDS). Blood 1995;86(Suppl 1):338a.
    • (1995) Blood , vol.86 , Issue.SUPPL. 1
    • Schuster, M.W.1    Thompson, J.A.2    Larson, R.3
  • 65
    • 0025349412 scopus 로고
    • Recurrent spleen enlargement during cyclic granulocyte-macrophage colony-stimulating factor therapy for myelodysplastic syndromes
    • [65] Delmer A, Karmochkine M, Cadiou M et al. Recurrent spleen enlargement during cyclic granulocyte-macrophage colony-stimulating factor therapy for myelodysplastic syndromes. Am J Hematol 1990;34:73-74.
    • (1990) Am J Hematol , vol.34 , pp. 73-74
    • Delmer, A.1    Karmochkine, M.2    Cadiou, M.3
  • 66
    • 0023783964 scopus 로고
    • Phase I/II study of recombinant human granulocyte-macrophage colony stimulating factor in aplastic anemia and myelodysplastic syndrome
    • [66] Antin JH, Smith BR, Holmes W et al. Phase I/II study of recombinant human granulocyte-macrophage colony stimulating factor in aplastic anemia and myelodysplastic syndrome. Blood 1988;72:705-713.
    • (1988) Blood , vol.72 , pp. 705-713
    • Antin, J.H.1    Smith, B.R.2    Holmes, W.3
  • 67
    • 0024498045 scopus 로고
    • Recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes - A phase I/II trial
    • [67] Ganser A, Völkers B, Greher J et al. Recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes - a phase I/II trial. Blood 1989;73:31-37.
    • (1989) Blood , vol.73 , pp. 31-37
    • Ganser, A.1    Völkers, B.2    Greher, J.3
  • 68
    • 0025809950 scopus 로고
    • Comparison of intravenous versus subcutaneous recombinant human granulocyte-macrophage colony-stimulating factor in patients with primary myelodysplasia
    • [68] Rosenfeld CS, Sulecki M, Evans C et al. Comparison of intravenous versus subcutaneous recombinant human granulocyte-macrophage colony-stimulating factor in patients with primary myelodysplasia. Exp Hematol 1991;19:273-277.
    • (1991) Exp Hematol , vol.19 , pp. 273-277
    • Rosenfeld, C.S.1    Sulecki, M.2    Evans, C.3
  • 69
    • 0024498901 scopus 로고
    • Subcutaneous granulocyte macrophage colony-stimulating factor in patients with myelodysplastic syndrome: Toxicity, pharmacokinetics, and hematological effects
    • [69] Thompson JA, Douglas JL, Kidd P et al. Subcutaneous granulocyte macrophage colony-stimulating factor in patients with myelodysplastic syndrome: toxicity, pharmacokinetics, and hematological effects. J Clin Oncol 1989;7:629-637.
    • (1989) J Clin Oncol , vol.7 , pp. 629-637
    • Thompson, J.A.1    Douglas, J.L.2    Kidd, P.3
  • 70
    • 0023571993 scopus 로고
    • Phase I study of recombinant human granulocyte-macrophage colony stimulating factor in patients with myelodysplastic syndrome
    • [70] Vadhan-Raj S, Kellagher MJ, Keating M et al. Phase I study of recombinant human granulocyte-macrophage colony stimulating factor in patients with myelodysplastic syndrome. N Engl J Med 1988;317:1545-1552.
    • (1988) N Engl J Med , vol.317 , pp. 1545-1552
    • Vadhan-Raj, S.1    Kellagher, M.J.2    Keating, M.3
  • 71
    • 0027481294 scopus 로고
    • Bone marrow histiocytic proliferation in association with colony-stimulating factor therapy
    • [71] Wilson PA, Ayscue LH, Jones GR et al. Bone marrow histiocytic proliferation in association with colony-stimulating factor therapy. Am J Clin Pathol 1993;99:311-313.
    • (1993) Am J Clin Pathol , vol.99 , pp. 311-313
    • Wilson, P.A.1    Ayscue, L.H.2    Jones, G.R.3
  • 72
    • 0000957436 scopus 로고
    • Restoration of impaired cytokine secretion from patients with myelodysplastic syndromes after in vivo treatment with GM-CSF or IL-3
    • [72] Maurer AB, Ganser A, Buhl R et al. Restoration of impaired cytokine secretion from patients with myelodysplastic syndromes after in vivo treatment with GM-CSF or IL-3. Leukemia 1993;7:189-195.
    • (1993) Leukemia , vol.7 , pp. 189-195
    • Maurer, A.B.1    Ganser, A.2    Buhl, R.3
  • 73
    • 0024204534 scopus 로고
    • Effect of recombinant GM-CSF and IL-3 on the metabolism of cytosine arabinoside in normal and leukemic human bone marrow cells
    • [73] Bhalla K, Birkhofer M, Arlin Z et al. Effect of recombinant GM-CSF and IL-3 on the metabolism of cytosine arabinoside in normal and leukemic human bone marrow cells. Leukemia 1988;2:810-813.
    • (1988) Leukemia , vol.2 , pp. 810-813
    • Bhalla, K.1    Birkhofer, M.2    Arlin, Z.3
  • 74
    • 0025120522 scopus 로고
    • Effect of interleukin-3 on cytosine arabinoside-mediated cytotoxicity of leukemic myeloblasts
    • [74] Brach M, Klein H, Platzer E et al. Effect of interleukin-3 on cytosine arabinoside-mediated cytotoxicity of leukemic myeloblasts. Exp Hematol 1990;18:748-753.
    • (1990) Exp Hematol , vol.18 , pp. 748-753
    • Brach, M.1    Klein, H.2    Platzer, E.3
  • 75
    • 0025805274 scopus 로고
    • Prolonged exposure to cytosine arabinoside in the presence of hematopoietic growth factors preferentially kills leukemic versus normal clonogenic cells
    • [75] Van der Lely N, De Witte T, Muus P et al. Prolonged exposure to cytosine arabinoside in the presence of hematopoietic growth factors preferentially kills leukemic versus normal clonogenic cells. Exp Hematol 1991;19:267-272.
    • (1991) Exp Hematol , vol.19 , pp. 267-272
    • Van Der Lely, N.1    De Witte, T.2    Muus, P.3
  • 76
    • 0028144466 scopus 로고
    • A randomized phase II study of low-dose cytosine arabinoside (LD-AraC) plus granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in myelodysplastic syndromes (MDS) with a high risk of developing leukemia
    • [76] Gerhartz HH, Marcus R, Delmer A et al. A randomized phase II study of low-dose cytosine arabinoside (LD-AraC) plus granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in myelodysplastic syndromes (MDS) with a high risk of developing leukemia. Leukemia 1994;8:16-23.
    • (1994) Leukemia , vol.8 , pp. 16-23
    • Gerhartz, H.H.1    Marcus, R.2    Delmer, A.3
  • 77
    • 0025271460 scopus 로고
    • Recombinant human granulocyte macrophage colony-stimulating factor and low-dose cytosine-arabinoside in the treatment of patients with myelodysplastic syndromes. A phase II study
    • [77] Höffken K, Overkamp F, Stirbu J et al. Recombinant human granulocyte macrophage colony-stimulating factor and low-dose cytosine-arabinoside in the treatment of patients with myelodysplastic syndromes. A phase II study. Onkologie 1990;13:33-37.
    • (1990) Onkologie , vol.13 , pp. 33-37
    • Höffken, K.1    Overkamp, F.2    Stirbu, J.3
  • 78
    • 0024995395 scopus 로고
    • Effect of treatment with rhGM-CSF and low-dose cytosine arabinoside on leukemic blast cells in patients with myelodysplastic syndromes
    • [78] Hoelzer D, Ganser A, Ottmann OG et al. Effect of treatment with rhGM-CSF and low-dose cytosine arabinoside on leukemic blast cells in patients with myelodysplastic syndromes. Haematol Blood Transfusion 1990;33:763-769.
    • (1990) Haematol Blood Transfusion , vol.33 , pp. 763-769
    • Hoelzer, D.1    Ganser, A.2    Ottmann, O.G.3
  • 79
    • 0023352145 scopus 로고
    • Low dose ara-C in acute non-lymphocytic leukemia and myelodysplastic syndromes: A review of 20 years experience
    • [79] Cheson BD, Simon R. Low dose ara-C in acute non-lymphocytic leukemia and myelodysplastic syndromes: a review of 20 years experience. Semin Oncol 1987;14(Suppl 1):126-133.
    • (1987) Semin Oncol , vol.14 , Issue.SUPPL. 1 , pp. 126-133
    • Cheson, B.D.1    Simon, R.2
  • 80
    • 0025005499 scopus 로고
    • The effect of recombinant human interleukin-3 in patients with normal hemopoiesis and in patients with secondary bone marrow failure
    • [80] Ganser A, Lindemann A, Seipelt G et al. The effect of recombinant human interleukin-3 in patients with normal hemopoiesis and in patients with secondary bone marrow failure. Blood 1990;76:666-676.
    • (1990) Blood , vol.76 , pp. 666-676
    • Ganser, A.1    Lindemann, A.2    Seipelt, G.3
  • 81
    • 0011171361 scopus 로고
    • A randomized trial of two doses of recombinant interleukin-3 in patients with myelodysplastic syndrome
    • [81] Bernstein SF, Gilliland DG, Aster J et al. A randomized trial of two doses of recombinant interleukin-3 in patients with myelodysplastic syndrome. Blood 1992;80(Suppl. 1):410a.
    • (1992) Blood , vol.80 , Issue.SUPPL. 1
    • Bernstein, S.F.1    Gilliland, D.G.2    Aster, J.3
  • 82
    • 0011200210 scopus 로고
    • Sequential treatment with recombinant human growth factors to compare activity of GM-CSF and IL3 in the treatment of primary myelodysplasia
    • [82] Dunbar CE, Smith D, Kimball J et al. Sequential treatment with recombinant human growth factors to compare activity of GM-CSF and IL3 in the treatment of primary myelodysplasia. Blood 1990;76(Suppl 1):141a.
    • (1990) Blood , vol.76 , Issue.SUPPL. 1
    • Dunbar, C.E.1    Smith, D.2    Kimball, J.3
  • 83
    • 0025082534 scopus 로고
    • Effects of recombinant human interleukin-3 in patients with myelodysplastic syndromes
    • [83] Ganser A, Seipelt G, Lindemann A et al. Effects of recombinant human interleukin-3 in patients with myelodysplastic syndromes. Blood 1990;76:455-462.
    • (1990) Blood , vol.76 , pp. 455-462
    • Ganser, A.1    Seipelt, G.2    Lindemann, A.3
  • 84
    • 0027267421 scopus 로고
    • Effect of long-term treatment with recombinant human interleukin-3 in patients with myelodysplastic syndromes
    • [84] Ganser A, Ottmann OG, Seipelt G et al. Effect of long-term treatment with recombinant human interleukin-3 in patients with myelodysplastic syndromes. Leukemia 1993;7:696-701.
    • (1993) Leukemia , vol.7 , pp. 696-701
    • Ganser, A.1    Ottmann, O.G.2    Seipelt, G.3
  • 85
    • 0025765633 scopus 로고
    • Phase i study of recombinant human interleukin-3 in patients with bone marrow failure
    • [85] Kurzrock R, Talpaz M, Estrov Z et al. Phase I study of recombinant human interleukin-3 in patients with bone marrow failure. J Clin Oncol 1991;9:1241-1250.
    • (1991) J Clin Oncol , vol.9 , pp. 1241-1250
    • Kurzrock, R.1    Talpaz, M.2    Estrov, Z.3
  • 86
    • 0028094426 scopus 로고
    • A phase I/II study of the interleukin-3 in patients with aplastic anemia and myelodysplasia
    • [86] Nimer SD, Pacquette RL, Ireland P et al. A phase I/II study of the interleukin-3 in patients with aplastic anemia and myelodysplasia. Exp Hematol 1994;22:875-880.
    • (1994) Exp Hematol , vol.22 , pp. 875-880
    • Nimer, S.D.1    Pacquette, R.L.2    Ireland, P.3
  • 87
    • 0028357534 scopus 로고
    • Induction of soluble IL-2 receptor in patients with myelodysplastic syndromes undergoing high-dose interleukin-3 treatment
    • [87] Seipelt G, Ganser A, Duranceyk H et al. Induction of soluble IL-2 receptor in patients with myelodysplastic syndromes undergoing high-dose interleukin-3 treatment. Ann Hematol 1994;68:167-170.
    • (1994) Ann Hematol , vol.68 , pp. 167-170
    • Seipelt, G.1    Ganser, A.2    Duranceyk, H.3
  • 88
    • 0025818028 scopus 로고
    • Soluble interleukin-2 (IL-2) receptor expression in patients with myelodysplastic syndromes is induced by granulocyte macrophage colony-stimulating factor and IL-3
    • [88] Zwierzina H, Herold M, Geissler D et al. Soluble interleukin-2 (IL-2) receptor expression in patients with myelodysplastic syndromes is induced by granulocyte macrophage colony-stimulating factor and IL-3. Blood 1991;77:2795-2796.
    • (1991) Blood , vol.77 , pp. 2795-2796
    • Zwierzina, H.1    Herold, M.2    Geissler, D.3
  • 89
    • 0027203322 scopus 로고
    • Induction of TNF-x in patients with myelodysplastic syndromes undergoing treatment with interleukin-3
    • [89] Seipelt G, Ganser A, Duranceyk H et al. Induction of TNF-x in patients with myelodysplastic syndromes undergoing treatment with interleukin-3. Br J Haematol 1993;84:749-751.
    • (1993) Br J Haematol , vol.84 , pp. 749-751
    • Seipelt, G.1    Ganser, A.2    Duranceyk, H.3
  • 90
    • 0029075385 scopus 로고
    • A phase I trial of recombinant human interleukin-6 in patients with myelodysplastic syndromes and thrombocytopenia
    • [90] Gordon MS, Nemunaitis J, Hoffman R et al. A phase I trial of recombinant human interleukin-6 in patients with myelodysplastic syndromes and thrombocytopenia. Blood 1995;85:3066-3076.
    • (1995) Blood , vol.85 , pp. 3066-3076
    • Gordon, M.S.1    Nemunaitis, J.2    Hoffman, R.3
  • 91
    • 0028887065 scopus 로고
    • A novel factor-dependent human myelodysplastic cell line, MDS92, contains haemopoietic cells of several lineages
    • [91] Toyhama K, Toyhama Y, Nakayama T, Ueda T, Nakamura T, Yoshida Y. A novel factor-dependent human myelodysplastic cell line, MDS92, contains haemopoietic cells of several lineages. Br J Haematol 1995;91:795-799.
    • (1995) Br J Haematol , vol.91 , pp. 795-799
    • Toyhama, K.1    Toyhama, Y.2    Nakayama, T.3    Ueda, T.4    Nakamura, T.5    Yoshida, Y.6
  • 92
    • 0025910001 scopus 로고
    • The clearance of a single i.v. bolus of recombinant human erythropoietin from the serum of patients with myelodysplastic syndromes and its effects on erythropoiesis
    • [92] Bowen D, Ehmer B, Neubert P et al. The clearance of a single i.v. bolus of recombinant human erythropoietin from the serum of patients with myelodysplastic syndromes and its effects on erythropoiesis. Exp Hematol 1991;19:613-616.
    • (1991) Exp Hematol , vol.19 , pp. 613-616
    • Bowen, D.1    Ehmer, B.2    Neubert, P.3
  • 93
    • 0028953367 scopus 로고
    • Efficacy of erythropoietin in the myelodysplastic syndromes: A meta-analysis of 205 patients from 17 studies
    • [93] Hellström-Lindberg E. Efficacy of erythropoietin in the myelodysplastic syndromes: a meta-analysis of 205 patients from 17 studies. Br J Haematol 1995;89:6771.
    • (1995) Br J Haematol , vol.89 , pp. 6771
    • Hellström-Lindberg, E.1
  • 94
    • 0029933087 scopus 로고    scopus 로고
    • The effect of iron chelation on haemopoiesis in MDS patients with transfusional iron overload
    • [94] Jensen PD, Heickendorff L, Pedersen B et al. The effect of iron chelation on haemopoiesis in MDS patients with transfusional iron overload. Br J Haematol 1996;94:288-299.
    • (1996) Br J Haematol , vol.94 , pp. 288-299
    • Jensen, P.D.1    Heickendorff, L.2    Pedersen, B.3
  • 95
    • 0027361750 scopus 로고
    • A combination of granulocyte colony-stimulating factor and erythropoietin may synergistically improve the anaemia in patients with myelodysplastic syndromes
    • [95] Hellström-Lindberg E, Birgegard G, Carlsson MD et al. A combination of granulocyte colony-stimulating factor and erythropoietin may synergistically improve the anaemia in patients with myelodysplastic syndromes. Leuk Lymph 1993;11:221-228.
    • (1993) Leuk Lymph , vol.11 , pp. 221-228
    • Hellström-Lindberg, E.1    Birgegard, G.2    Carlsson, M.D.3
  • 96
    • 0028260993 scopus 로고
    • Failure of combination therapy with recombinant granulocyte colony-stimulating factor and erythropoietin in myelodysplastic syndromes
    • [96] Imamura M, Kobayashi M, Kobayashi S et al. Failure of combination therapy with recombinant granulocyte colony-stimulating factor and erythropoietin in myelodysplastic syndromes. Ann Hematol 1994;68:163-166.
    • (1994) Ann Hematol , vol.68 , pp. 163-166
    • Imamura, M.1    Kobayashi, M.2    Kobayashi, S.3
  • 97
    • 0029940725 scopus 로고    scopus 로고
    • Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: Evidence for in vivo synergy
    • [97] Negrin RS, Stein R, Doherty K et al. Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: evidence for in vivo synergy. Blood 1996;87:4076-4081.
    • (1996) Blood , vol.87 , pp. 4076-4081
    • Negrin, R.S.1    Stein, R.2    Doherty, K.3
  • 98
    • 0027752906 scopus 로고
    • Subcutaneous recombinant human erythropoietin for the treatment of anemia in myelodysplastic syndromes
    • [98] Ghio R, Balleari E, Ballestrero A et al. Subcutaneous recombinant human erythropoietin for the treatment of anemia in myelodysplastic syndromes. Acta Haematol 1993;90:58-64.
    • (1993) Acta Haematol , vol.90 , pp. 58-64
    • Ghio, R.1    Balleari, E.2    Ballestrero, A.3
  • 99
    • 0027371975 scopus 로고
    • Recombinant human granulocyte macrophage colony-stimulating factor plus erythropoietin may improve anemia in selected patients with myelodysplasia
    • [99] Hansen PB, Hippe E, Hellström-Lindberg E et al. Recombinant human granulocyte macrophage colony-stimulating factor plus erythropoietin may improve anemia in selected patients with myelodysplasia. Am J Hematol 1993;44:229-236.
    • (1993) Am J Hematol , vol.44 , pp. 229-236
    • Hansen, P.B.1    Hippe, E.2    Hellström-Lindberg, E.3
  • 100
    • 0001204341 scopus 로고
    • Combined treatment of myelodysplastic syndromes (MDS) with recombinant human interleukin-3 (IL-3) and erythropoietin (EPO)
    • [100] List AL, Noyes W, Power J et al. Combined treatment of myelodysplastic syndromes (MDS) with recombinant human interleukin-3 (IL-3) and erythropoietin (EPO). Blood 1993;82(Suppl 1):377a.
    • (1993) Blood , vol.82 , Issue.SUPPL. 1
    • List, A.L.1    Noyes, W.2    Power, J.3
  • 101
    • 0001204341 scopus 로고
    • Treatment of myelodysplastic syndromes (MDS) with the combination of interleukin-3 and erythropoietin
    • [101] Verhoef G, Demuynck H, Zachäe P et al. Treatment of myelodysplastic syndromes (MDS) with the combination of interleukin-3 and erythropoietin. Blood 1993;82(Suppl 1):377a.
    • (1993) Blood , vol.82 , Issue.SUPPL. 1
    • Verhoef, G.1    Demuynck, H.2    Zachäe, P.3
  • 102
    • 0028123294 scopus 로고
    • A phase I/II study of sequential interleukin-3 and granulocyte-macrophage colony-stimulating factor in myelodysplastic syndromes
    • [102] Nand S, Sosman J, Godwin JE et al. A phase I/II study of sequential interleukin-3 and granulocyte-macrophage colony-stimulating factor in myelodysplastic syndromes. Blood 1994;83:357-360.
    • (1994) Blood , vol.83 , pp. 357-360
    • Nand, S.1    Sosman, J.2    Godwin, J.E.3
  • 103
    • 0026680585 scopus 로고
    • Sequential in vivo treatment with two recombinant human hematopoietic growth factors (interleukin-3 and granulocyte-macrophage colony-stimulating factor) as a new therapeutic modality to stimulate hematopoiesis
    • [103] Ganser A, Lindemann A, Ottmann OG et al. Sequential in vivo treatment with two recombinant human hematopoietic growth factors (interleukin-3 and granulocyte-macrophage colony-stimulating factor) as a new therapeutic modality to stimulate hematopoiesis. Blood 1992;79:2583-2591.
    • (1992) Blood , vol.79 , pp. 2583-2591
    • Ganser, A.1    Lindemann, A.2    Ottmann, O.G.3
  • 104
    • 0029068452 scopus 로고
    • A controlled study of recombinant human granulocyte colony-stimulating factor in elderly patients after treatment for acute myelogenous leukemia
    • [104] Dombret H, Chastang C, Fenaux P et al. A controlled study of recombinant human granulocyte colony-stimulating factor in elderly patients after treatment for acute myelogenous leukemia. N Engl J Med 1995;332:1678-1683.
    • (1995) N Engl J Med , vol.332 , pp. 1678-1683
    • Dombret, H.1    Chastang, C.2    Fenaux, P.3
  • 105
    • 0025187881 scopus 로고
    • Effect of granulocyte-colony-stimulating factor after intensive induction therapy in relapsed or refractory acute leukemia
    • [105] Ohno R, Tomonaga M, Kobayashi T et al. Effect of granulocyte-colony-stimulating factor after intensive induction therapy in relapsed or refractory acute leukemia. N Engl J Med 1990;323:871-877.
    • (1990) N Engl J Med , vol.323 , pp. 871-877
    • Ohno, R.1    Tomonaga, M.2    Kobayashi, T.3
  • 106
    • 0029015209 scopus 로고
    • A randomized placebo-controlled phase III study of granulocyte-macrophage colony-stimulating factor in adult patients ( > 55 to 70 years of age) with acute myelogenous leukemia. A study of the Eastern Cooperative Oncology Group (E 1490)
    • [106] Rowe JM, Andersen J, Mazza J et al. A randomized placebo-controlled phase III study of granulocyte-macrophage colony-stimulating factor in adult patients ( > 55 to 70 years of age) with acute myelogenous leukemia. A study of the Eastern Cooperative Oncology Group (E 1490). Blood 1995;86:457-462.
    • (1995) Blood , vol.86 , pp. 457-462
    • Rowe, J.M.1    Andersen, J.2    Mazza, J.3
  • 107
    • 0029033064 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia
    • [107] Stone R, Berg DT, George SL et al. Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia. N Engl J Med 1995;332:1671-1677.
    • (1995) N Engl J Med , vol.332 , pp. 1671-1677
    • Stone, R.1    Berg, D.T.2    George, S.L.3
  • 108
    • 0030034127 scopus 로고    scopus 로고
    • Feasability of peripheral blood progenitor cell harvest and transplantation in patients with poor-risk myelodysplastic syndromes
    • [108] Demuynck H, Delforge M, Verhoef GEG et al. Feasability of peripheral blood progenitor cell harvest and transplantation in patients with poor-risk myelodysplastic syndromes. Br J Haematol 1996;92:351-359.
    • (1996) Br J Haematol , vol.92 , pp. 351-359
    • Demuynck, H.1    Delforge, M.2    Verhoef, G.E.G.3
  • 109
    • 0028805708 scopus 로고
    • Polyclonal primitive hematopoietic progenitors can be detected in mobilized peripheral blood from patients with high-risk myelodysplastic syndromes
    • [109] Delforge M, Demuynck H, Vandenberghe P et al. Polyclonal primitive hematopoietic progenitors can be detected in mobilized peripheral blood from patients with high-risk myelodysplastic syndromes. Blood 1995;86:3660-3667.
    • (1995) Blood , vol.86 , pp. 3660-3667
    • Delforge, M.1    Demuynck, H.2    Vandenberghe, P.3
  • 110
    • 0028344644 scopus 로고
    • Use of granulocyte colony-stimulating factor before, during, and after fludarabine plus cytarabine induction therapy of newly diagnosed acute myelogenous leukemia or myelodysplastic syndromes: Comparison with fludarabine plus cytarabine without granulocyte colony-stimulating factor
    • [110] Estey EH, Thall P, Andreef M et al. Use of granulocyte colony-stimulating factor before, during, and after fludarabine plus cytarabine induction therapy of newly diagnosed acute myelogenous leukemia or myelodysplastic syndromes: comparison with fludarabine plus cytarabine without granulocyte colony-stimulating factor. J Clin Oncol 1994;12:671-678.
    • (1994) J Clin Oncol , vol.12 , pp. 671-678
    • Estey, E.H.1    Thall, P.2    Andreef, M.3
  • 111
    • 0028073456 scopus 로고
    • Recombinant human granulocyte-macrophage colony-stimulating factor in combination with standard induction chemotherapy in acute myeloid leukemia evolving from myelodysplastic syndromes: A pilot study
    • [111] Bernell P, Kimby E, Hast R. Recombinant human granulocyte-macrophage colony-stimulating factor in combination with standard induction chemotherapy in acute myeloid leukemia evolving from myelodysplastic syndromes: a pilot study. Leukemia 1994;8:1631-1639.
    • (1994) Leukemia , vol.8 , pp. 1631-1639
    • Bernell, P.1    Kimby, E.2    Hast, R.3
  • 112
    • 0023678691 scopus 로고
    • Growth characteristics of marrow hematopoietic progenitor/precursor cells from patients on a phase I clinical trial with purified recombinant human granulocyte-macrophage colony-stimulating factor
    • [112] Broxmeyer HE, Cooper S, Williams DE et al. Growth characteristics of marrow hematopoietic progenitor/precursor cells from patients on a phase I clinical trial with purified recombinant human granulocyte-macrophage colony-stimulating factor. Exp Hematol 1988;16:594-602.
    • (1988) Exp Hematol , vol.16 , pp. 594-602
    • Broxmeyer, H.E.1    Cooper, S.2    Williams, D.E.3
  • 113
    • 0024470396 scopus 로고
    • Stimulation of nonclonal hematopoiesis and suppression of the neoplastic clone after treatment with recombinant human granulocyte-macrophage colony-stimulating factor in a patient with therapy-related myelodysplastic syndrome
    • [113] Vadhan-Raj S, Broxmeyer HE, Spitzer G et al. Stimulation of nonclonal hematopoiesis and suppression of the neoplastic clone after treatment with recombinant human granulocyte-macrophage colony-stimulating factor in a patient with therapy-related myelodysplastic syndrome. Blood 1989;74:1491-1498.
    • (1989) Blood , vol.74 , pp. 1491-1498
    • Vadhan-Raj, S.1    Broxmeyer, H.E.2    Spitzer, G.3
  • 114
    • 0025135233 scopus 로고
    • Effects of recombinant human interleukin-3 on human hematopoietic progenitor and precursor cells in vivo
    • [114] Ottmann OG, Ganser A, Seipelt G et al. Effects of recombinant human interleukin-3 on human hematopoietic progenitor and precursor cells in vivo. Blood 1990;76:1494-1502.
    • (1990) Blood , vol.76 , pp. 1494-1502
    • Ottmann, O.G.1    Ganser, A.2    Seipelt, G.3
  • 115
    • 0026539156 scopus 로고
    • Recombinant human erythropoietin for treatment of myelodysplastic syndromes
    • [115] Rafanelli D, Grossi A, Longo G et al. Recombinant human erythropoietin for treatment of myelodysplastic syndromes. Leukemia 1992;6:323-327.
    • (1992) Leukemia , vol.6 , pp. 323-327
    • Rafanelli, D.1    Grossi, A.2    Longo, G.3
  • 116
    • 0025735327 scopus 로고
    • Recombinant human erythropoietin in patients with myelodysplastic syndromes
    • [116] Schouten HC, Vellenga E, van Rhenen DJ et al. Recombinant human erythropoietin in patients with myelodysplastic syndromes. Leukemia 1991;5:432-436.
    • (1991) Leukemia , vol.5 , pp. 432-436
    • Schouten, H.C.1    Vellenga, E.2    Van Rhenen, D.J.3
  • 117
    • 0025913199 scopus 로고
    • Effect of subcutaneously administered human recombinant erythropoietin on erythropoiesis in patients with myelodysplasia
    • [117] Van Kamp H, Tineke C, Prinsze-Postema TC et al. Effect of subcutaneously administered human recombinant erythropoietin on erythropoiesis in patients with myelodysplasia. Br J Haematol 1991;78:488-493.
    • (1991) Br J Haematol , vol.78 , pp. 488-493
    • Van Kamp, H.1    Tineke, C.2    Prinsze-Postema, T.C.3
  • 118
    • 0029145108 scopus 로고
    • Responsiveness to stem cell factor (SCF) of peripheral blood colony-forming cells from patients with myelodysplastic syndromes (MDS)
    • [118] Masters GS, Baines P, Tang C, Bowen D, Burnett AK. Responsiveness to stem cell factor (SCF) of peripheral blood colony-forming cells from patients with myelodysplastic syndromes (MDS). Leuk Res 1995;19:561-566.
    • (1995) Leuk Res , vol.19 , pp. 561-566
    • Masters, G.S.1    Baines, P.2    Tang, C.3    Bowen, D.4    Burnett, A.K.5
  • 119
    • 0029024169 scopus 로고
    • The effect of stem-cell factor, interleukin-3 and erythropoietin on in vitro erythropoiesis in myelodysplastic syndromes
    • [119] Verbeek W, Vehmeyer K, Wörmann B, Hiddemann W. The effect of stem-cell factor, interleukin-3 and erythropoietin on in vitro erythropoiesis in myelodysplastic syndromes. J Cancer Res Clin Oncol 1995;121:338-342.
    • (1995) J Cancer Res Clin Oncol , vol.121 , pp. 338-342
    • Verbeek, W.1    Vehmeyer, K.2    Wörmann, B.3    Hiddemann, W.4
  • 120
    • 0028158659 scopus 로고
    • Stem cell factor improvement of proliferation and maintenance of hematopoietic progenitors in myelodysplastic syndromes
    • [120] Piacibello W, Sanavio F, Bresso P et al. Stem cell factor improvement of proliferation and maintenance of hematopoietic progenitors in myelodysplastic syndromes. Leukemia 1994;8:250-257.
    • (1994) Leukemia , vol.8 , pp. 250-257
    • Piacibello, W.1    Sanavio, F.2    Bresso, P.3
  • 121
    • 0028337826 scopus 로고
    • Evidence for nonclonal hematopoietic progenitor cell populations in bone marrow of patients with myelodysplastic syndromes
    • [121] Asano H, Ohashi H, Ichihara M et al. Evidence for nonclonal hematopoietic progenitor cell populations in bone marrow of patients with myelodysplastic syndromes. Blood 1994;84:588-594.
    • (1994) Blood , vol.84 , pp. 588-594
    • Asano, H.1    Ohashi, H.2    Ichihara, M.3
  • 122
    • 0028224769 scopus 로고
    • Growth analysis of marrow CD34-positive hematopoietic progenitor cells in patients with myelodysplastic syndromes
    • [122] Asano H, Hotta T, Ichihara M, Murate T, Kobayashi M, Saito H. Growth analysis of marrow CD34-positive hematopoietic progenitor cells in patients with myelodysplastic syndromes. Leukemia 1994;8:833-838.
    • (1994) Leukemia , vol.8 , pp. 833-838
    • Asano, H.1    Hotta, T.2    Ichihara, M.3    Murate, T.4    Kobayashi, M.5    Saito, H.6
  • 123
    • 0028318183 scopus 로고
    • Mast cell growth factor (c-kit ligand) restores growth of multipotent progenitors in myelodysplastic syndrome
    • [123] Glinsman-Gibson B, Spier C, Baier M, Taetle R, Broudy VC, List AF. Mast cell growth factor (c-kit ligand) restores growth of multipotent progenitors in myelodysplastic syndrome. Leukemia 1994;8:827-832.
    • (1994) Leukemia , vol.8 , pp. 827-832
    • Glinsman-Gibson, B.1    Spier, C.2    Baier, M.3    Taetle, R.4    Broudy, V.C.5    List, A.F.6
  • 124
    • 0027979602 scopus 로고
    • Effects of recombinant human stem cell factor (rh-SCF) on colony formation and long-term bone marrow cultures (LTBMC) in patients with myelodysplastic syndromes
    • [124] Soligo D, Servida F, Cortelezzi A et al. Effects of recombinant human stem cell factor (rh-SCF) on colony formation and long-term bone marrow cultures (LTBMC) in patients with myelodysplastic syndromes. Eur J Haematol 1994;52:53-60.
    • (1994) Eur J Haematol , vol.52 , pp. 53-60
    • Soligo, D.1    Servida, F.2    Cortelezzi, A.3
  • 125
    • 0027941810 scopus 로고
    • Effect of stem cell factor (c-kit ligand) on clonogenic leukemic precursor cells: Synergy with other hematopoietic growth factors
    • [125] Wu HK, Chiba S, Hirai H, Takaku F, Yazaki Y. Effect of stem cell factor (c-kit ligand) on clonogenic leukemic precursor cells: synergy with other hematopoietic growth factors. Am J Hematol 1994;47:328-330.
    • (1994) Am J Hematol , vol.47 , pp. 328-330
    • Wu, H.K.1    Chiba, S.2    Hirai, H.3    Takaku, F.4    Yazaki, Y.5
  • 126
    • 0026795839 scopus 로고
    • Cytogenetic effects on cells derived from patients with myelodysplastic syndromes during treatment with hematopoietic growth factors
    • [126] Verhoef G, Van Den Berghe H, Boogaerts M. Cytogenetic effects on cells derived from patients with myelodysplastic syndromes during treatment with hematopoietic growth factors. Leukemia 1992;6:766-769.
    • (1992) Leukemia , vol.6 , pp. 766-769
    • Verhoef, G.1    Van Den Berghe, H.2    Boogaerts, M.3
  • 127
    • 0025852635 scopus 로고
    • In vivo effects of granulocyte-macrophage colony-stimulating factor and interleukin-3 on clonal and non-clonal cell populations in patients with clonal hematopoietic disorders
    • [127] Ganser A, Janssen JWG, Ottmann OG et al. In vivo effects of granulocyte-macrophage colony-stimulating factor and interleukin-3 on clonal and non-clonal cell populations in patients with clonal hematopoietic disorders. Leukemia 1991;5:487-492.
    • (1991) Leukemia , vol.5 , pp. 487-492
    • Ganser, A.1    Janssen, J.W.G.2    Ottmann, O.G.3
  • 128
    • 0027476532 scopus 로고
    • Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: Lineage, response to growth factor therapy and clonal expansion
    • [128] Anastasi J, Feng J, LeBeau MM et al. Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy and clonal expansion. Blood 1993;81:1580-1585.
    • (1993) Blood , vol.81 , pp. 1580-1585
    • Anastasi, J.1    Feng, J.2    LeBeau, M.M.3
  • 129
    • 0024841855 scopus 로고
    • Hematologic and cytogenetic findings in myelodysplastic syndromes treated with recombinant human granulocyte colony-stimulating factor
    • [129] Ohyashiki K, Ohyashiki JH, Toyama K et al. Hematologic and cytogenetic findings in myelodysplastic syndromes treated with recombinant human granulocyte colony-stimulating factor. Jpn J Cancer Res 1989;80:848-854.
    • (1989) Jpn J Cancer Res , vol.80 , pp. 848-854
    • Ohyashiki, K.1    Ohyashiki, J.H.2    Toyama, K.3
  • 130
    • 0027482698 scopus 로고
    • Lowdose filgrastim therapy for chronic neutropenia
    • [130] Kaczmarski RS, Mufti GJ. Lowdose filgrastim therapy for chronic neutropenia. N Engl J Med 1993;329:1280-1281.
    • (1993) N Engl J Med , vol.329 , pp. 1280-1281
    • Kaczmarski, R.S.1    Mufti, G.J.2
  • 131
    • 0024553901 scopus 로고
    • Effect of recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome with excess blasts
    • [131] Herrmann F, Lindemann A, Klein H et al. Effect of recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome with excess blasts. Leukemia 1989;3:335-338.
    • (1989) Leukemia , vol.3 , pp. 335-338
    • Herrmann, F.1    Lindemann, A.2    Klein, H.3
  • 132
    • 0011178711 scopus 로고
    • A randomized phase I/II study with recombinant human GMCSF in patients (pts) with myelodysplastic syndromes at a relatively low risk of developing acute leukemia
    • [132] Willemze R, Visani G, de Witte Th et al. A randomized phase I/II study with recombinant human GMCSF in patients (pts) with myelodysplastic syndromes at a relatively low risk of developing acute leukemia. Blood 1990;76(Suppl 1):337a.
    • (1990) Blood , vol.76 , Issue.SUPPL. 1
    • Willemze, R.1    Visani, G.2    De Witte, Th.3
  • 133
    • 0026463803 scopus 로고
    • Clinical and cytogenetic responses to granulocyte-macrophage colony-stimulating factor in therapy-related myelodysplasia
    • [133] Gradishar WJ, LeBeau MM, O'Laughlin R et al. Clinical and cytogenetic responses to granulocyte-macrophage colony-stimulating factor in therapy-related myelodysplasia. Blood 1992;80:2463-2470.
    • (1992) Blood , vol.80 , pp. 2463-2470
    • Gradishar, W.J.1    LeBeau, M.M.2    O'Laughlin, R.3
  • 134
    • 0027515118 scopus 로고
    • Phase II study of recombinant human granulocyte-macrophage colony-stimulating factor in myelodysplastic syndrome and aplastic anemia
    • [134] Takahasha M, Yoshida Y, Kaku K et al. Phase II study of recombinant human granulocyte-macrophage colony-stimulating factor in myelodysplastic syndrome and aplastic anemia. Acta Haematol 1993;89:189-194.
    • (1993) Acta Haematol , vol.89 , pp. 189-194
    • Takahasha, M.1    Yoshida, Y.2    Kaku, K.3
  • 135
    • 0029115252 scopus 로고
    • Effects of long-term treatment with recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome
    • [135] Yoshida Y, Nakahata T, Shibata A et al. Effects of long-term treatment with recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome. Leuk Lymph 1995;18:457-463.
    • (1995) Leuk Lymph , vol.18 , pp. 457-463
    • Yoshida, Y.1    Nakahata, T.2    Shibata, A.3
  • 136
    • 0025013590 scopus 로고
    • Improvement of anemia by recombinant human erythropoietin in patients with myelodysplastic syndromes and aplastic anemia
    • [136] Bessho M, Jinnai I, Matsuda A et al. Improvement of anemia by recombinant human erythropoietin in patients with myelodysplastic syndromes and aplastic anemia. Int J Cell Clon 1990;8:445-458.
    • (1990) Int J Cell Clon , vol.8 , pp. 445-458
    • Bessho, M.1    Jinnai, I.2    Matsuda, A.3
  • 137
    • 0001620661 scopus 로고
    • Evaluation of erythropoietin (EPO) in the treatment of patients with myelodysplastic syndromes (MDS) - Preclinical data supporting a rationale for sequential therapy with granulocyte-macrophage colony stimulating factor (GM-CSF) and EPO
    • [137] Oster W, Krumwieh D, Brune T et al. Evaluation of erythropoietin (EPO) in the treatment of patients with myelodysplastic syndromes (MDS) - preclinical data supporting a rationale for sequential therapy with granulocyte-macrophage colony stimulating factor (GM-CSF) and EPO. J Cancer Clin Oncol 1990;116(Suppl):280.
    • (1990) J Cancer Clin Oncol , vol.116 , Issue.SUPPL. , pp. 280
    • Oster, W.1    Krumwieh, D.2    Brune, T.3
  • 138
    • 0025647617 scopus 로고
    • High-dose recombinant human erythropoietin for treatment of anemia in myelodysplastic syndromes and paroxysmal nocturnal hemoglobinuria: A pilot study
    • [138] Stebler C, Ticheili A, Dazzi H et al. High-dose recombinant human erythropoietin for treatment of anemia in myelodysplastic syndromes and paroxysmal nocturnal hemoglobinuria: a pilot study. Exp Hematol 1990;18:1204-1208.
    • (1990) Exp Hematol , vol.18 , pp. 1204-1208
    • Stebler, C.1    Ticheili, A.2    Dazzi, H.3
  • 139
    • 0025827934 scopus 로고
    • The treatment of anaemia in the myelodysplastic syndromes with recombinant human erythropoietin
    • [139] Bowen D, Culligan D, Jacobs A. The treatment of anaemia in the myelodysplastic syndromes with recombinant human erythropoietin. Br J Haematol 1991;77:419-423.
    • (1991) Br J Haematol , vol.77 , pp. 419-423
    • Bowen, D.1    Culligan, D.2    Jacobs, A.3
  • 140
    • 0026319476 scopus 로고
    • Treatment of myelodysplastic syndromes with recombinant human erythropoietin
    • [140] Hellström E, Birgegard G, Locker D et al. Treatment of myelodysplastic syndromes with recombinant human erythropoietin. Eur J Haematol 1991;47:355-360.
    • (1991) Eur J Haematol , vol.47 , pp. 355-360
    • Hellström, E.1    Birgegard, G.2    Locker, D.3
  • 141
    • 0026062644 scopus 로고
    • Pharmacologic doses of recombinant human erythropoietin in the treatment of myelodysplastic syndromes
    • [141] Stein RS, Abels RI, Krantz SB. Pharmacologic doses of recombinant human erythropoietin in the treatment of myelodysplastic syndromes. Blood 1991;78:1658-1663.
    • (1991) Blood , vol.78 , pp. 1658-1663
    • Stein, R.S.1    Abels, R.I.2    Krantz, S.B.3
  • 142
    • 0026035696 scopus 로고
    • Recombinant human erythropoietin at high dose is effective for the treatment of the anemia of myelodysplastic syndromes
    • [142] Laporte JPN, Isnard F, Fenaux P. Recombinant human erythropoietin at high dose is effective for the treatment of the anemia of myelodysplastic syndromes. Contrib Nephrol 1991;88:271-272.
    • (1991) Contrib Nephrol , vol.88 , pp. 271-272
    • Laporte, J.P.N.1    Isnard, F.2    Fenaux, P.3
  • 143
    • 0026410636 scopus 로고
    • Erythropoietin treatment in patients with myelodysplastic syndrome and anemia
    • [143] Kurzrock R, Talpaz M, Estey E et al. Erythropoietin treatment in patients with myelodysplastic syndrome and anemia. Leukemia 1991;5:985-990.
    • (1991) Leukemia , vol.5 , pp. 985-990
    • Kurzrock, R.1    Talpaz, M.2    Estey, E.3
  • 144
    • 0026557392 scopus 로고
    • Recombinant human erythropoietin for the treatment of anemia in the myelodysplastic syndromes: A clinical and erythrokinetic assessment
    • [144] Verhoef GE, Zachee P, Ferrant A et al. Recombinant human erythropoietin for the treatment of anemia in the myelodysplastic syndromes: a clinical and erythrokinetic assessment. Ann Hematol 1992;64:16-21.
    • (1992) Ann Hematol , vol.64 , pp. 16-21
    • Verhoef, G.E.1    Zachee, P.2    Ferrant, A.3
  • 145
    • 0026538225 scopus 로고
    • Erythropoietin therapy of myelodysplastic syndromes
    • [145] Shepherd JD, Currie CJ, Sparling TG et al. Erythropoietin therapy of myelodysplastic syndromes. Blood 1992;79:1891-1892.
    • (1992) Blood , vol.79 , pp. 1891-1892
    • Shepherd, J.D.1    Currie, C.J.2    Sparling, T.G.3
  • 146
    • 0026516808 scopus 로고
    • Subcutaneous erythropoietin for treatment of refractory anemia in hematologic disorders: Results of a phase I/II clinical trial
    • [146] Cazzola M, Ponchio L, Beguin Y et al. Subcutaneous erythropoietin for treatment of refractory anemia in hematologic disorders: results of a phase I/II clinical trial. Blood 1992;79:29-37.
    • (1992) Blood , vol.79 , pp. 29-37
    • Cazzola, M.1    Ponchio, L.2    Beguin, Y.3
  • 147
    • 0027241779 scopus 로고
    • High doses of intravenous recombinant erythropoietin for the treatment of anaemia in myelodysplastic syndrome
    • [147] Goy A, Belanger C, Casadevall N et al. High doses of intravenous recombinant erythropoietin for the treatment of anaemia in myelodysplastic syndrome. Br J Haematol 1993;84:232-237.
    • (1993) Br J Haematol , vol.84 , pp. 232-237
    • Goy, A.1    Belanger, C.2    Casadevall, N.3
  • 148
    • 0027478320 scopus 로고
    • Erythropoietin treatment for chronic anemia of selected hematological malignancies and solid tumors
    • [148] Ludwig H, Fritz E, Leitgeb C et al. Erythropoietin treatment for chronic anemia of selected hematological malignancies and solid tumors. Ann Oncol 1993;4:161-167.
    • (1993) Ann Oncol , vol.4 , pp. 161-167
    • Ludwig, H.1    Fritz, E.2    Leitgeb, C.3
  • 149
    • 0027230892 scopus 로고
    • Serum erythropoietin level and marrow erythroid infiltration predict response to recombinant-human-erythropoietin in myelodysplastic syndromes
    • [149] Depaoli L, Levis A, Isabella N et al. Serum erythropoietin level and marrow erythroid infiltration predict response to recombinant-human-erythropoietin in myelodysplastic syndromes. Haematologica 1993; 78:118-122.
    • (1993) Haematologica , vol.78 , pp. 118-122
    • Depaoli, L.1    Levis, A.2    Isabella, N.3
  • 150
    • 0027263163 scopus 로고
    • Serial changes in endogenous erythropoietin levels in patients with myelodysplastic syndromes and aplastic anemia undergoing erythropoietin treatment
    • [150] Yoshida Y, Anzai N, Kawabata H et al. Serial changes in endogenous erythropoietin levels in patients with myelodysplastic syndromes and aplastic anemia undergoing erythropoietin treatment. Ann Hematol 1993;66:175-180.
    • (1993) Ann Hematol , vol.66 , pp. 175-180
    • Yoshida, Y.1    Anzai, N.2    Kawabata, H.3
  • 151
    • 0027419815 scopus 로고
    • Recombinant human erythropoietin (rHuEPO) for treatment of myelodysplastic syndrome
    • [151] Zeigler ZR, Jones D, Rosenfeld CS et al. Recombinant human erythropoietin (rHuEPO) for treatment of myelodysplastic syndrome. Stem Cells 1993;11:49-55.
    • (1993) Stem Cells , vol.11 , pp. 49-55
    • Zeigler, Z.R.1    Jones, D.2    Rosenfeld, C.S.3
  • 152
    • 0027521757 scopus 로고
    • Prediction of response to treatment with recombinant erythropoietin in myelodysplastic syndromes
    • [152] Stenke L, Wallvik J, Celsing F et al. Prediction of response to treatment with recombinant erythropoietin in myelodysplastic syndromes. Leukemia 1993;7:1324-1327.
    • (1993) Leukemia , vol.7 , pp. 1324-1327
    • Stenke, L.1    Wallvik, J.2    Celsing, F.3
  • 153
    • 0027650997 scopus 로고
    • Phase II clinical study of recombinant erythropoietin on the anemia of myelodysplastic syndrome
    • [153] Urabe A, Mizoguchi H, Takaku F et al. Phase II clinical study of recombinant erythropoietin on the anemia of myelodysplastic syndrome. Rinsho Ketsueko 1993;4: 928-936.
    • (1993) Rinsho Ketsueko , vol.4 , pp. 928-936
    • Urabe, A.1    Mizoguchi, H.2    Takaku, F.3
  • 154
    • 0027377687 scopus 로고
    • Characterization of circulating erythrocytes from myelodysplastic patients treated with recombinant human erythropoietin
    • [154] Shapiro S, Gershon H, Rosenbaum H et al. Characterization of circulating erythrocytes from myelodysplastic patients treated with recombinant human erythropoietin. Leukemia 1993;7:1328-1333.
    • (1993) Leukemia , vol.7 , pp. 1328-1333
    • Shapiro, S.1    Gershon, H.2    Rosenbaum, H.3
  • 155
    • 0027730520 scopus 로고
    • Recombinant erythropoietin in myelodysplastic syndromes: Whom to treat and how? more questions than answers
    • [155] Mittelman M. Recombinant erythropoietin in myelodysplastic syndromes: whom to treat and how? More questions than answers. Acta Haematol 1993;90:53-57.
    • (1993) Acta Haematol , vol.90 , pp. 53-57
    • Mittelman, M.1
  • 156
    • 0026725896 scopus 로고
    • Therapy with human recombinant erythropoietin in patients with myelodysplastic syndromes
    • [156] Razzano M, Caslini C, Cortellazzo S et al. Therapy with human recombinant erythropoietin in patients with myelodysplastic syndromes. Br J Haematol 1992;81:628-630.
    • (1992) Br J Haematol , vol.81 , pp. 628-630
    • Razzano, M.1    Caslini, C.2    Cortellazzo, S.3
  • 157
    • 0027175013 scopus 로고
    • Is recombinant human erythropoietin treatment in myelodysplastic syndromes worthwhile?
    • [157] Spiriti MAA, Petti MC, Latagliata R et al. Is recombinant human erythropoietin treatment in myelodysplastic syndromes worthwhile? Leuk Lymph 1993;9:79-83.
    • (1993) Leuk Lymph , vol.9 , pp. 79-83
    • Spiriti, M.A.A.1    Petti, M.C.2    Latagliata, R.3
  • 158
    • 0027730521 scopus 로고
    • Recombinant human erythropoietin in patients with myelodysplastic syndromes and myelofibrosis
    • [158] Mohr B, Herrmann R, Huhn D. Recombinant human erythropoietin in patients with myelodysplastic syndromes and myelofibrosis. Acta Haematol 1993;90:65-70.
    • (1993) Acta Haematol , vol.90 , pp. 65-70
    • Mohr, B.1    Herrmann, R.2    Huhn, D.3
  • 159
    • 0028226499 scopus 로고
    • Efficacy of recombinant human erythropoietin in the treatment of refractory anemias without excess of blasts in myelodysplastic syndromes
    • [159] Isnard F, Najman A, Jaar B et al. Efficacy of recombinant human erythropoietin in the treatment of refractory anemias without excess of blasts in myelodysplastic syndromes. Leuk Lymph 1994;12:307-314.
    • (1994) Leuk Lymph , vol.12 , pp. 307-314
    • Isnard, F.1    Najman, A.2    Jaar, B.3
  • 160
    • 0027998574 scopus 로고
    • Treatment with recombinant human erythropoietin in patients with myelodysplastic syndromes
    • [160] Stone RM, Bernstein SH, Demetri G et al. Treatment with recombinant human erythropoietin in patients with myelodysplastic syndromes. Leuk Leuk Res 1994;18:769-776.
    • (1994) Leuk Leuk Res , vol.18 , pp. 769-776
    • Stone, R.M.1    Bernstein, S.H.2    Demetri, G.3
  • 161
    • 0028900601 scopus 로고
    • The use of r-HuEpo in the treatment of anemia related to myelodysplasia (MDS)
    • [161] Rose EH, Abels RI, Nelson RA et al. The use of r-HuEpo in the treatment of anemia related to myelodysplasia (MDS). Br J Haematol 1995;89:831-837.
    • (1995) Br J Haematol , vol.89 , pp. 831-837
    • Rose, E.H.1    Abels, R.I.2    Nelson, R.A.3


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