Detection and cellular localization of heparin-binding epidermal growth factor-like growth factor mRNA and protein in human atherosclerotic tissue

Journal of Molecular and Cellular Cardiology

Volumn 29, Issue 6, 1997, Pages 1639-1648

  Reape, Theresa J ^a,b   Wilson, Victoria J ^a,b   Kanczler, Janos M ^c   Ward, Jeremy P T ^a   Burnand, Kevin G ^a   Thomas, Chris R ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c New Frontiers Science Park North ^*

Author keywords

Atherosclerosis; Gene expression; Heparin binding epidermal growth factor like growth factor; Macrophage; Vascular smooth muscle cell

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; MITOGENIC AGENT; POLYCLONAL ANTIBODY; SULFUR 35;

ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BIOPSY; BLOOD VESSEL WALL; CELL CULTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MACROPHAGE; MESSENGER RNA SYNTHESIS; MONOCYTE; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROBE; SMOOTH MUSCLE FIBER; STAINING; VASCULAR SMOOTH MUSCLE;

EID: 0031172593     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1997.0399     Document Type: Article

References (24)

1. ABRAHAM JA, DAMM D, BAJARDI, A, MILLER J, KLAGSBRUN M, EZEKOWITZ AB, 1993. Heparin-binding EGF-like growth factor: characterization of rat and mouse cDNA clones, protein domain conservation across species, and transcript expression in tissues. Biochem Biophys Res Commun. 190: 125-133.
2. AVIEZER D, YAYON A, 1994. Heparin-dependent binding and autophosphorylation of epidermal growth factor (EGF) receptor by heparin-binding EGF-like growth factor but not by EGF. Proc Natl Acad Sci USA 91: 12173-12177.
3. CHOMOCZYNSKI P, SACCHI N, 1987. Single-step method of RNA isolation by acid guanidium thiocynate-phenolchloroform extraction. Anal Biochem 162: 156-159.
4. DLUZ SM, HIGASHIYAMA S, DAMM D, ABRAHAM JA, KLAGSBRUN M, 1993. Heparin-binding epidermal growth factor-like growth factor expression in cultured fetal human vascular smooth muscle cells. Induction of mRNA levels and secretion of active mitogen. J Biol Chem 268: 18330-18334.
5. FERNS GA, RAINES EW, SPRUGEL KH, MOTANI AS, REIDY MA, Ross R, 1991. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody of PDGF. Science 253: 1129-1132.
6. GRANT MB, WARGOVICH TJ, ELLIS ES, CABALLERO S, MANSOUR M, PEPINE CJ, 1994. Localization of insulin-like growth factor-I and inhibition of coronary smooth muscle cell growth by somatostatin analogues in human coronary smooth muscle cells. Circulation 89: 1511-1517.
7. HIGASHIYAMA S, ABRAHAM JA, MILLER J, FIDDES JC, KLAGSBRUN M, 1991. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 251: 936-939.
8. HIGASHIYAMA S, ABRAHAM JA, DAMM D, KLAGSBURN M, 1993a. Heparin-binding EGF-like growth factor (HBEGF) synthesis by smooth muscle cells. Horm Res (Basel) 42: 9-13.
9. HIGASHIYAMA S, ABRAHAM JA, KLAGSBRUN, 1993b. Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate. J Cell Biol 122: 933-940.
10. HUGHES SE, CROSSMAN D, HALL PA, 1993, Expression of basic and acidic fibroblast growth factors and their receptor in normal and atherosclerotic human arteries. Cardiovasc Res 27: 1214-1219.
11. MIYAGAWA J, HIGASHIYAMA S, KAWATA S, INUI Y, TAMURA S, YAMAMOTO K, NISHIDA M, NAKAMURA T, YAMASHITA S, MATSUZAWA Y, TANIGUCHI N, 1995. Localization of heparin-binding EGF-like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques. J Clin Invest 95: 404-411.
12. MIANO JM, VLASIC N, TOTA RR, STEMERMAN MB, 1992. Smooth muscle cell immediate-early gene and growth factor activation follows vascular injury. Arterioscl Thromb 13: 211-219.
13. MORITA T, YOSHIZUMI M, KURIHARA H, MAEMURA K, NAGAI R, YAZAKI Y, 1993. Sheer stress increases heparin-binding epidermal growth factor-like growth factor mRNA levels in human vascular endothelial cells. Biochem Biophys Res Commun 197: 256-262.
14. NAKANO T, RAINES EW, ABRAHAM JA, WENZEL FG, IV, HIGASHIYAMA S, KLAGSBRUN M, 1993. Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells. J Biol Chem 268: 22941-22947.
15. NAKANO T, RAINES EW, ABRAHAM JA, KLAGSBRUN M, ROSS R, 1994. Lysophosphatidylcholine upregulates the level of heparin-binding epidermal growth factor-like growth factor mRNA in human monocytes. Proc Natl Acad Sci USA 91: 1069-1073.
16. OLSON NE, CHAO S, LINDNER V, REIDY MA, 1992. Intimal smooth muscle cell proliferation after balloon catheter injury. The role of basic fibroblast growth factor. Am J Path 140: 1017-1023.
17. RAINES EW, ROSS R, 1993. Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis. Br Heart J (Suppl.) 69: S30-S37.
18. ROSS R, 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362: 801-809.
19. SALOMON RN, UNDERWOOD R, DOYLE MV, WANG A, LIBBY P, 1992. Increased apolipoprotein E and c-fms gene expression without elevated interleukin 1 or 6 levels indicate selective activation of macrophage functions in advanced human atheroma. Proc Natl Acad Sci USA 89: 2814-2818.
20. SAMBROOK J, FRITSCH E, MANIATIS T, 1989. In: Nolan C. (ed.). Molecular Cloning. A Laboratory Manual. Cold Spring Harbour Laboratory Press USA, 7.37-7.52.
21. SANNA PP, FOLSOM DP, BARIZO MJ, HIRSCH MJ MELIA KR, MACIEJEWSKI-LENOIR D, BLOOM FE, 1993. Chronic ethanol intake decreases vasopressin mRNA content in the rat hypothalamus. Mol Brain Res 19: 241-245.
22. STARY HC, CHANDLER B, GLAGOV S, GUYTON JR, INSULL W, JR ROSENEELD ME, SCHAFFER SA, SCHWARTZ CJ, WAGNER WD, WISSLER RW, 1994. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. Circulation 89: 2462-2478.
23. TEMIZER DH, YOSHIZUM M, PERRELLA MA, SUSANNI EE, QUERTERMOUS T, LEE M, 1992. Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotesin II in rat aortic smooth muscle cells. J Biol Chem 267: 24892-24896.
24. WILCOX JN, 1993. Molecular biology: insight into the causes and prevention of restenosis. Am J Cardiol 72: 88E-95E.