Prevalence, geographic distribution, and genealogical investigation of Machado-Joseph disease in the Azores (Portugal)

Human Biology

Volumn 69, Issue 3, 1997, Pages 383-391

  Lima, Manuela ^a   Mayer, Francine ^b   Coutinho, Paula ^c   Abade, Augusto ^d  

^a UNIVERSITY OF THE AZORES   (Portugal)

^b UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^c HOSPITAL DE SANTO ANTÓNIO   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

AZORES; EPIDEMIOLOGY; FOUNDER EFFECT; MACHADO JOSEPH DISEASE

Indexed keywords

EID: 0031172472     PISSN: 00187143     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Coutinho, P. 1992. A doença de Machado-Joseph: Tentativa de definição. Ph.D. dissertation, University of Oporto, Oporto, Portugal.
2. Instituto Nacional de Estatĩstica. 1992. XIII Recenseamento Geral da População: Resultados definitivos. Lisbon, Portugal: Imprensa Nacional-Casa da Moeda.
3. Kawaguchi, Y., T. Okamoto, M. Taniwaki et al. 1994. CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1. Nature Genet. 8:221-228.
4. Nakano K., D. Dawson, and A. Spence. 1972. Machado disease: A hereditary ataxia in Portuguese emigrants to Massachusetts. Neurology 22:49-55.
5. Sequeiros, J., and P. Coutinho. 1993. Epidemiology and clinical aspects of Machado-Joseph disease. Adv. Neurol. 61:139-153.
6. Takiyama, Y., M. Nishizawa, H. Tanaka et al. 1993. The gene for Machado-Joseph disease maps to human chromosome 14q. Nature Genet. 4(3):300-304.