Oligodendrocytes express gap junction proteins connexin32 and connexin45

GLIA

Volumn 20, Issue 2, 1997, Pages 101-114

  Dermietzel, R ^a   Farooq, M ^b   Kessler, J A ^b   Althaus, H ^c   Hertzberg, E L ^b   Spray, D C ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

Connexin32; Connexin45; Electrical coupling; Gap junction; Oligodendrocytes

Indexed keywords

CONNEXIN 32; CONNEXIN 45; GAP JUNCTION PROTEIN; PRIMER DNA;

ANIMAL; ARTICLE; BIOSYNTHESIS; BRAIN; CATTLE; CELL CULTURE; CELL JUNCTION; CELL MEMBRANE POTENTIAL; CYTOLOGY; ELECTRIC CONDUCTIVITY; MYELIN SHEATH; OLIGODENDROGLIA; PATCH CLAMP; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SWINE; ULTRASTRUCTURE;

ANIMALS; BRAIN; CATTLE; CELLS, CULTURED; CONNEXINS; DNA PRIMERS; ELECTRIC CONDUCTIVITY; GAP JUNCTIONS; MEMBRANE POTENTIALS; MYELIN SHEATH; OLIGODENDROGLIA; PATCH-CLAMP TECHNIQUES; POLYMERASE CHAIN REACTION; SWINE;

EID: 0031172215     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(199706)20:2<101::AID-GLIA2>3.0.CO;2-C     Document Type: Article

References (62)

1. Barrio, C., Suchyna, T., Bargiello, T., Xu, L.X., Roginski, R.S., Bennett, M.V.L., and Nicholson, B.J. (1991) Gap junctions formed by connexin 26 and connexin 32 alone and in combination are differently affected by applied voltage. Proc. Natl. Acad. Sci. (U.S.A.), 88:8411-8414.
2. Bennett, M.V.L. and Goodenough, D.A. (1978) Gap junctions, electrotonic coupling, and intercellular communication. Neurosci. Res. Prog. Bull., 16:373-485.
3. Bennett, M.V.L., Barrio, T.A., Spray, D.C., Hertzberg, E.L., and Saez, J.C. (1991) Gap junctions: new tools, new answers, new question. Neuron, 6:305-320.
4. Beyer, E.G., Kistler, J., Paul, D.L., and Goodenough, D.A. (1989) Antisera directed against connexin43 peptides react with a 43 kDa protein localized to gap junctions in myocardium and other tissues. J. Cell Biol., 108:595-605.
5. Bergoffen, J., Scherer, S.S., Wang, S., Scott, M.O., Bone, L.J., Paul, D.L., Chen, K., Lensch, M.W., Chance, P.F., and Fischbeck, K.H. (1993) Connexin mutations in X-linked Chorcot-Marie-Tooth disease. Science, 262:2039-2042.
6. Beyer, E.C., Paul, D.L., and Goodenough, D.A. (1990) Connexin family of gap junction proteins. J. Membrane Biol., 116:187-194.
7. Brightman, M.W. and Reese, T.S. (1969) Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell Biol., 648-677.
8. Bruzzone, R., White, T.W., Scherer, S.S., Fischbeck, K.H., and Paul, D.L. (1995) Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease. Neuron, 13:1253-1260.
9. Bunge, R.P. (1968) Glial cells and the central myelin sheath. Physiol. Rev., 48:197-251.
10. Bunge, R.P. (1981) The development of myelin and myelin-related cells. Trends Neurosci., 4:175-177.
11. Burt, J.M. and Spray, D.C. (1988) Ionotropic agents modulate gap junctional conductance between cardiac myocytes. Am. J. Physiol., 254:H1206-H1210.
12. Butterweck, A., Gergs, U., Elfgang, C., Willecke, K., and Traub, O. (1994) Immunochemical characterization of the gap junction protein connexin45 in mouse kidney and transfected human HeLa cells. J. Membr. Biol., 141:247-256.
13. Campos de Carvalho, A., Spray, D.C., and Bennett, M.V.L. (1984) pH dependence of transmission at electrotonic synapses of the crayfish septate axon. Brain Res., 321:279-286.
14. Chomczynski, P. and Sacchi, N. (1987) Single step method of RNA isolation by guanidinium thiocyanytephenolchloroform extraction. Anal. Biochem., 162:156-159.
15. Dermietzel, R. (1978) The oligodendrocytic junctional complex. Cell Tiss. Res., 193:61-72.
16. Dermietzel, R., Leibstein, A., Frixen, U., JanssenTimmen, U., Traub, O., and Willecke, K. (1984) Gap junctions in several tissues share antigenic determinants with liver gap junctions. EMBO J., 3:2261-2270.
17. Dermietzel, R., Traub, O., Hwang, T.K., Beyer, E., Bennett, M.V.L., Spray, D.C., and Willecke, K. (1989) Differential expression of three gap junction proteins in developing and mature brain tissues. Proc. Natl. Acad. Sci. U.S.A., 86:10148-10152.
18. Dermietzel, R., Hertzberg, E.L., Kessler, J.A., and Spray, D.C. (1991) Gap junctions between cultured astrocytes: Immunocytochemical, molecular, and electrophysiological analysis. J. Neurosci., 11:1421-1432.
19. Dermietzel, R. and Spray, D.C. (1993) Gap junction in the brain: where, what type, how many and why? Trends Neurosci., 16:186-192.
20. Dermietzel, R. (1996) Molecular diversity and plasticity of gap junctions in the nervous system. In: Gap Junctions in the Nervous System. Spray, D.C., Dermietzel, R., eds. R.G. Landes, Austin, pp. 14-38.
21. Giaume, C., Fromaget, C., El Aoumari, A., Cordier, J., Glowinski, J., and Gros, D. (1991) Gap junctions in cultured astrocytes: Single channel currents and characterization of channel forming protein. Neuron, 6:133-143.
22. Guerrier, A., Fonlupt, P., Morand, I., Rabillou, R., Audebet, C., Krutovskikh, V., Gros, D., Rousset, B., and Munari-Silem, Y. (1995) Gap junctions and cell polarity: connexin32 and connexin43 expressed in polarized thyroid epithelial cells assemble into separate gap junctions, which are located in distinct regions of the lateral plasma membrane domain. J. Cell Sci., 108:2609-2617.
23. Haefliger, J.A., Bruzzone, R., Jenkins, N.A., Gilbert, D.J., Copeland, N.G., and Paul, D.L. (1992) Four novel members of the connexin family of gap junction protein. Molecular cloning, expression, and chromosome mapping. J. Biol. Chem., 267:2057-2064.
24. Hennemann, H., Schwarz, H.J., and Willecke, K. (1992) Characterization of gap junction genes expressed in F9 embryonic carcinoma cells: Molecular cloning of mouse connexin31 and -45 cDNAs. Eur. J. Cell Biol., 57:51-58.
25. Harris, A.I., Spray, D.C., and Bennett, M.V.L. (1981) Kinetic properties of a voltage dependent junctional conductance. J. Gen. Physiol., 7:95-117.
26. Hertzberg, E.L. and Skibbens, V. (1984) A protein homologous to the 27,000 dalton liver gap junction protein is present in a wide variety of species and tissue. Cell, 39:61-69.
27. Hertzberg, E.L., Diskert, R.M., Tiller, A.A., Zhou, J., and Ceak, R.G. (1988) Topology of the Mr 27000 liver gap junction protein. J. Biol. Chem., 263:19105-19111.
28. Kettenmann, H. and Ransom, B.R. (1988) Electrical coupling between astrocytes and between oligodendrocytes studied in mammalian cell cultures. Glia, 1:64-73.
29. Kettenmann, H. and Ransom, B.R. (1995) Neuroglia. Oxford University Press, New York,
30. Knobler, R.L., Stempak, J.G., and Laurencin, M. (1976) Nonuniformity of the oligodendroglial ensheathment of axons during myelination in the developing rat central nervous system. J. Ultrastruct. Res., 55:417-432.
31. Kunzelmann, P., Blümcke, I., Traub, O., Dermietzel, R., Willecke, K., Co-expression of connexin45 and -32 in oligodendrocytes of the rat brain. J. Neurocytol. (in press).
32. Loewenstein, W.R. (1981) Junctional intercellular communication: The cell to cell membrane channel. Physiol. Rev., 61:829-913.
33. Maniatis, T., Fritsch, E.F., and Sambrook, J. (1982) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory. Cold Spring Harbor.
34. Massa, P.T., and Mugnaini, E. (1982) Cell junctions and intramembrane particles of astrocytes and oligodendrocytes: A freeze fracture study. Neuroscience, 7:523-538.
35. Massa, P.T. and Mugnaini, E. (1985) Cell cell interactions and characteristic plasma membrane features of cultured rat glial cells. Neuroscience, 14:695-709.
36. Mathews, M.A. and Duncan, D. (1971) A quantitative study of the morphological changes accompanying the initiation of myelin production in the periphera nervous system. J. Comp. Neurol., 142:1-22.
37. Moreno, A.P., Arellano, R.O., Rivera, A., and Ramon, F. (1991a) Humoral factors reduce gap junction sensitivity to cytoplasmic pH. II. In vitro manipulations. Am. J. Physiol., 260:C1039-C1045.
38. Moreno, A.P., Campos de Carvalho, A.C., Verselis, V., Eghbali, B., and Spray, D.C. (1991b). Voltage dependent gap junction channels are formed by connexin 32, the major gap junction protein of rat liver. Biophys. J., 59:920-925.
39. Moreno, A.P., Eghbali, B., and Spray, D.C. (1993) Connexin32 gap junction channels in stably transfected cells: Unitary conductance. Biophys. J., 60:1254-1255.
40. Moreno, A.P., Laing, J.G., Beyer, B.C., and Spray, D.C. (1995) Properties of gap junction channels formed of connexin45 endogenously expressed in human hepatoma (SKHep1) cells. Am. J. Physiol., 268:C356-365.
41. Mugnaini, E. (1982) Membrane spezialisations in neuro glial cells and at neuron glia contacts. In: Neuronal Glial Cell Interrelationships. Dahlem Konferenzen 1982. Sears, T.A., ed. Springer Verlag, Berlin, Heidelberg, New York.
42. Nelles, E., Bützler, C., Jung, D., Temme, A., Gabriel, H-D., Dahl, U., Stümpel, F., Jungermann, K., Zielsak, J., Toyka, K.V., Dermietzel, R., and Willecke, K. Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice. Proc. Natl. Acad. Sci. U.S.A., 93:9565-9570.
43. Neuhaus, I.M., Dahl, G., and Werner, R. (1995) Use of alternate promotors for tissue specific expression of the gene coding for connexin32. Gene, 158:257-262.
44. Norton, W.T., Farooq, M., Fields, K.L., and Raine, C.S. (1983) The longterm culture of bulk-isolated bovine oligodendroglia from adult brain. Brain Res., 270:299-310.
45. Peters, A. and Vaughn, J.E. (1970) Morphology and the development of the myelin sheath. In: Myelination. Davidson, A.N. and Peters, A. eds. Charles Thomas, Springfield, Ill., pp. 3-79.
46. Peters, A., Palay, S.L., and Webster, de F.H. (1991) The Fine Structure of the Nervous System. Oxford Press, New York, 494 pp.
47. Ransom, B.R. and Kettenmann, H. (1990) Electrical coupling, without dye coupling, between mammalian astrocytes and oligodendrocytes in cell culture. Glia, 3:258-266.
48. Robinson, S.R., Hampson, C., Munro, M.N., and Vaney, D.I. (1993) Unidirectional coupling of gap junctions between neuroglia. Science, 262:1072-1074.
49. Saez, J.C., Spray, D.C., Nairn, A., Hertzberg, E.L., Greengard, P., and Bennett, M.V.L. (1986) cAMP increases junctional conductance and stimulates phophorylation of the 27 kDA principal gap junction polypeptide. Proc. Natl Acad. Sci. U.S.A., 86:2708-2712.
50. Scherer, S.S., Deschênes, S.M., Yi-tian, X., Grinspan, J.B., Fishbeck, K.H., and Paul, D.L. (1995) Connexin32 is a myelin-related protein in the PNS and CNS. J. Neurosci., 15:8251-8294.
51. Spiegel, K., Wong, V., and Kessler, J.A. (1990) Translational control of somatostatin in cultured sympathetic neurons. Neuron, 4:303-311.
52. Spray, D.C. and Bennett, M.V.L. (1985) Physiology and pharmacology of gap junctions. Annu. Rev. Physiol., 47:281-303.
53. + ions in amphibian embryonic cells is independent of voltage sensitivity. Proc. Natl. Acad. Sci. U.S.A., 83:3533-3536.
54. Spray, D.C. and Saez, J.C. (1987) Agents that regulate gap junctional conductance: Sites of action and specificities. Adv. Mod. Environ. Toxicol., 14:126.
55. Spray, D.C., Bennett, M.V.L., Campos de Carvalho, A.C., Eghbali, B., Moreno, A.P., and Verselis, V. (1991) Transjunctional voltage dependence of gap junction channels. In: Biophysics of Gap Junction Channels. Perrachia, C. ed. CRC Press, Boca Rodan, FL, pp. 97-116.
56. Spray, D.C., and Dermietzel, R. (1995) X-linked dominant Charcot-Marie-Tooth disease and other potential gap junction diseases of the nervous system. Trends Neurosci., 18:256-262.
57. Steinberg, T.H., Civitelli, R., Geist, S.T., Robertson, A.J., Hick, E., Veenstra, R.D., Wang, H.Z., Warlow, P.M., Laing, J.G., and Beyer, E. (1994) Connexin43 and connexin45 form gap junctions with different molecular permeabilities in osteoblastic cells. EMBO J., 13:744-750.
58. Stevenson, B.R., Siliciano, J.D., Mooseker, M.S., and Goodenough, D.A. (1986) Identification of ZO1: A high molecular weight polypeptide associated with the tight junction (Zonula Occludens) in a variety of epithelia. J. Cell Biol., 103:755-766.
59. Traub, O., Look, J.D.P., and Willecke, K. (1987) Cyclic adenosine monophosphate stimulates biosynthesis and phosphorylation of the 26 kDa gap junction protein in cultured mouse hepatocytes. Eur. J. Cell Biol., 43:4854.
60. Traub, O., Look, J., Dermietzel, R., Brummer, F., Hülser, D., and Willecke, K. (1989) Comparative characterization of the 21 kDa and 26 kDa gap junction proteins in murine liver and cultured hepatocytes. J. Cell Biol., 108:1039-1051.
61. Veenstra, R., Wang, H.Z., Beyer, E.C., and Brink, P.R. (1994) Selective dye and ionic permeability of gap junction channels formed by connexin45. Circ. Res., 75:483-490.
62. Verselis, V.K., Ginter, C.S., and Bargiello, T.A. (1994) Opposite voltage gating polarities of two closely related connexins. Nature, 368:348-351.