Effects of cromakalim and glibenclamide on myocardial high energy phosphates and intracellular pH during ischemia-reperfusion: 31P NMR studies

Journal of Molecular and Cellular Cardiology

Volumn 29, Issue 6, 1997, Pages 1665-1673

  Docherty, John C ^a   Gunter, Heather E ^a   Kuzio, Bozena ^a   Shoemaker, Lori ^a   Yang, Luojia ^a   Deslauriers, Roxanne ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

31P NMR; ATP sensitive potassium channels; Intracellular pH; Ischemia; Lactate; Reperfusion

Indexed keywords

ADENOSINE TRIPHOSPHATE; CROMAKALIM; GLIBENCLAMIDE; LACTIC ACID; POTASSIUM CHANNEL STIMULATING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PH; CONTROLLED STUDY; HEART FUNCTION; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HIGH ENERGY PHOSPHATE; MALE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TIME; VOLKMANN CONTRACTURE;

EID: 0031172154     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1997.0404     Document Type: Article

References (18)

1. ATP openers protect against increased cytosolic calcium during ischaemia and reperfusion. J Mol Cell Cardiol 27: 1809-1817.
2. BERGMEYER HU, 1983. Methods of enzymatic analysis. New York: Academic Press, 582.
3. + channels protect the myocardium against ischemia/reperfusion damage. Circ Res 69: 571-581.
4. + channel opener, and cromakalin in rat and dog. Eur J Pharmacol 294: 271-280.
5. + channels during metabolic stress in cardiac muscle. J Pharmacol Exper Ther 266: 456-467.
6. GALINANES M, SHATTOCK MJ, HEARSE DJ, 1992. Effects of potassium channel modulation during global ischemia in isolated rat heart with and without cardioplegia. Cardiovasc Res 26: 1063-1068.
7. GROVER GJ, 1994. Protective effects of ATP-sensitive potassium-channel openers in experimental myocardial ischemia. J Cardiovasc Pharmacol 24 (Suppl. 4): S18-S27.
8. GROVER GJ, NEWBURGER J, SLEPH PG, DZWONCZYK S, TAYLOR SC, AHMED SY, ATWAL KS, 1991. Cardioprotective effects of the potassium channel opener cromakalim: stereoselectivity and effects on myocardial adenine nucleotides. J Pharmacol Exper Ther 257: 156-162.
9. GROVER GJ, MCCULLOUGH JR, D'ALONZO AJ, SARGENT CA, ATWAL KS, 1995. Cardioprotective profile of the cardiac-selective ATP-sensitive potassium channel opener BMS-180448. J Cardiovasc Pharmacol 25: 40-50.
10. HEARSE DJ, 1995. Activation of ATP-sensitive potassium channels: a novel pharmacological approach to myocardial protection? Cardiovasc Res 30: 1-17.
11. KOLOCASSIDES KG, GALINANES M, HEARSE DJ, 1995. Pre-conditioning accelerates contracture and ATP depletion in blood-perfused rat hearts. Am J Physiol 269: H1415-H1420.
12. KUPRIYANOV VV, LAKOMKIN VL, STEINSCHEIDER AY, SEVERING MY, KAPELKO VI, RUUGE EK, SAKS VA, 1988. Relationship between pre-ischemic ATP and glycogen content and post-ischemic recovery of rat heart. J Mol Cell Cardiol 20: 1151-1162.
13. + channels involves high-energy phosphate preservation. Am J Physiol 265: H1809-H1818.
14. MITANI A, KINOSHITA K, FUKAMACHI K, SAKAMOTO M, KURISU K, TSURUHARA Y, FUKUMURA F, NAKASHIMA A, TOKUNAGA K, 1991. Effects of glibenclamide and nicorandil on cardiac function during ischemia and reperfusion in isolated perfused rat hearts. Am J Physiol 261: H1864-H1871.
15. 31P magnetic resonance. J Biol Chem 260: 7276-7278.
16. SCHAFFER SW, POOLE CG, LAMPSON WG, KRAMER JH, 1981. Effect of tolbutamide on the mechanical function of the isolated rat heart subjected to global ischemia. J Mol Cell Cardiol 13: 341-345.
17. SCHAFFER SW, TAN BH, MOZAFFARI MS, 1985. Effect of gliburide on myocardial metabolism and function. Am J Med 79 (Suppl. 3B): 48-52.
18. 87Rb NMR study. J Mol Cell Cardiol 27: 1377-1392.