The mechanical properties of simulated collagen fibrils

Journal of Biomechanics

Volumn 30, Issue 6, 1997, Pages 549-554

  Parkinson, John ^a   Brass, Andy ^a   Canova, Giles ^b   Brechet, Yves ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b Centre National de la Recherche Scientifique   (France)

Author keywords

Collagen; Computer modeling; Mechanical properties

Indexed keywords

COMPUTER SIMULATION; ENTROPY; MOLECULAR STRUCTURE; MORPHOLOGY; PARTICLES (PARTICULATE MATTER); STRESSES; TENSILE STRENGTH; TENSILE TESTING; TISSUE;

FIBRILLOGENESIS; OSTEOGENESIS IMPERFECTA;

COLLAGEN;

COLLAGEN FIBRIL;

ARTICLE; BIOMECHANICS; COMPUTER MODEL; FORCE; OSTEOGENESIS IMPERFECTA; PRIORITY JOURNAL; PROTEIN STRUCTURE; TENSILE STRENGTH;

EID: 0031172143     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9290(96)00151-0     Document Type: Article

References (16)

1. Ashby, M. F. and Jones, D. R. H. (1986) Engineering Materials 2: An Introduction to Microstructures, Processing and Design. Pergamon, Oxford.
2. Byers, P. H. and Steiner, R. D. (1992) Osteogenesis imperfecta. Ann. Rev. Med. 43, 269-282.
3. Charmet, J. C., Roux, S. and Guyon, E. (eds.) (1990) Disorder and Fracture. Plenum, New York.
4. Decitres, X. D., Brechet, Y., Kubin, L. P. and Braillon, P. (1994) Numerical modelling of the evolution of the architecture of trabecu-lar bone - damage accumulation and failure. Modell. Sim. Mat. Engng 2, 135-146.
5. Gibson, L. J. and Ashby, M. F. (1988) Cellular Solids: Structure and Properties. Pergamon, Oxford.
6. Kadler, K. E., Hojima, Y. and Prockop, D. J. (1987) Assembly of collagen fibrils de Novo by the cleavage of the type I pC-collagen with procollagen C-proteinase. J. Biol. Chem. 260, 15, 696-15, 701.
7. Katz, J. L. (1980) The structure and biomechanics of bone. In The mechanical Properties of Biological Materials, eds J. F. V. Vincent and J. D. Currey, pp. 137-168. Cambridge University Press, Cambridge.
8. Mammone, J. F. and Hudson, S. M. (1993) Micromechanics of bone strength and fracture. J. Biomechanics 26, 439-446.
9. Martin, R. B. (1991) Determinants of the mechanical properties of bone. J. Biomechanics (suppl. 1) 24, 79-88.
10. Okada, T., Hayashi, T. and Ikada, Y. (1992) Degradation of collagen suture in vitro and in vivo. Biomaterials 13, 448-454.
11. Parkinson, J., Kadler, K. E. and Brass, A. (1995) Simple physical model of collagen fibrillogenesis based on diffusion limited aggregation. J. Mol. Biol. 247, 823-831.
12. Parry, D. A. D. (1988) The molecular and fibrillar structure of collagen and its relationship to the mechanical properties of connective tissue. Biophys. Chem. 29, 195-209.
13. Parry, D. A. D. and Craig, A. S. (1984) Growth and development of collagen fibrils in connective tissue. In Ultrastructure of the Connective Tissue Matrix, eds. A. Ruggeri and P. M. Motta, pp. 34-64. Martinus Nijhoff, Boston.
14. Prockop, D. J. and Kivirikko, K. I. (1995) Collagens: molecular biology, diseases and potentials for therapy. Ann. Rev. Biochem. 64, 403-434.
15. Torre-Blanco, A., Adachi, E., Hojima, Y., Wootton, J. A. M., Minor, R. P. and Prockop, D. J. (1992) Temperature-induced post-tranlational over-modification of type I procollagen. J. Biol. Chem. 267, 2650-2655.
16. Woo, S. L.-Y., Johnson, G. A. and Smith, B. A. (1993) Mathematical modelling of ligaments and tendons. J. Biomech. Engng Trans. ASME 115, 468-473.