Expression of alpha-1-antichymotrypsin in prostate carcinoma

Journal of Korean Medical Science

Volumn 12, Issue 3, 1997, Pages 228-233

  Cho, Nam Hoon ^a,b   Park, Chanil ^a   Park, Dong Soo ^a  

^a Yonsei University   (South Korea)

^b Yong dong Illite Co Ltd   (South Korea)

Author keywords

Alpha 1 antichymotrypsin; Immunohistochemistry; Prostate carcinoma

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN;

ARTICLE; BIOSYNTHESIS; CARCINOMA; HUMAN; MALE; METABOLISM; PATHOLOGY; PROSTATE; PROSTATE HYPERTROPHY; PROSTATE TUMOR; PROSTATIC INTRAEPITHELIAL NEOPLASIA;

ALPHA 1-ANTICHYMOTRYPSIN; CARCINOMA; HUMANS; MALE; PROSTATE; PROSTATIC HYPERPLASIA; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROSTATIC NEOPLASMS;

EID: 0031159781     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.1997.12.3.228     Document Type: Article

References (30)

1. Lilja H, Christensson A, Dahlen U, Matikainen MT, Nilsson O, Pettersson K, Lovgren T. Prostate-specific antigen in human serum occurs predominantly in complex with α 1-antichymotrypsin. Clin Chem 1991 ; 37 : 618-25.
2. Lilja H. Regulation of the enzymatic activity of prostate-specific antigen and its reaction with extracellular protease inhibitors in prostate cancer. Scand J Clin Lab Invest 1995 ; 220 (suppl) : 47-56.
3. Christensson A, Laurell CB, Lilja H. Enzymatic activity of prostate specific antigen and its reaction with extracellular serine proteinase inhibitors. Eur J Biochem 1990 ; 194 : 755-63.
4. Stenman U, Leinonen J, Alfthan H, Rannikko S, Tuhkanen K, Alfthan O. A complex between prostate-specific antigen and α 1-antichymotrypsin is the major forms of prostate-specific antigen in serum of patients with prostatic cancer: Assay of the complex improves clinical sensitivity for cancer. Cancer Res 1991 ; 51 : 222-6.
5. Wood WG, van der Sloot E, Bohle A. The establishment and evaluation of luminescent-labelled immunometric assays for prostate specific antigen-alpha-1-antichy motrypsin complexes in serum. Eur J Clin Chem Clin Biochem 1991 ; 29 : 787-94.
6. Christensson A, Bjork T, Nilsson O, Dahlen U, Matikainen M, Cockett ATK, Abrahamsson P, Lilja H. Serum prostate specific antigen complexed to α1-antichymotrypsin as an indicator of prostate cancer. J Urol 1993 ; 150 : 100-5.
7. Lilja H. Significance of different molecular forms of serum PSA ; The free, noncomplexed form of PSA versus that complexed to α1-antichymotrypsin. Urol Clin North Am 1993 ; 20 : 681-6.
8. Leinonen J, Lovgren T, Vornanen T, Stenman U. Double-label time resolved immunofluorometric assay of prostate specific antigen and of its complex with α1-antichymotrypsin. Clin Chem 1993 ; 39 : 2098-103.
9. Stamey TA, Chen Z, Prestigiacomo A. Serum prostate specific antigen binding α1-antichymotrypsin: influence of cancer volume, location and therapeutic selection of resistant clones. J Urol 1994 ; 152 : 1510-4.
10. Ansong K. Alpha-1 antichymotrypsin production in PSA producing cells is common in prosate cancer but rare in benign prostatic hyperplasia. Letter to the editor. Urology 1994 ; 44 : 296.
11. Huber PR, Mattarelli G, Strittmatter B, Steenbrugge GJV, Schmid H, Maurer A. In vivo and in vitro complex formation of prostate specific antigen with α1-antichymotrypsin. Prostate 1995 ; 17 : 166-75.
12. Lilza H. Biologic function of prostate specific antigen: enzyme action and reactions with extracellular protease inhibitors. Eur Urol 1995 ; 27 (suppl 2) : 2-3.
13. Wu JT, Zhang P. Wang T, Wilson L, Astill M. Evaluation of free PSA isoforms, PSA complex formation and specificity of anti-PSA antibodies by HPLC and PAGE-immunoblotting techniques. J Clin Lab Anal 1995 ; 9 : 1-14.
14. Wu JT, Wilson L, Zhang P, Meikle AW, Stephenson R. Correlation of serum concentrations of PSA-ACT complex with total PSA in random and serial specimens from patients with BPH and prostate cancer. J Clin Lab Anal 1995 ; 9 : 15-24.
15. Bjork T, Hurkko S, Bjaartell A, Sant'agnese A, Abrahamsson P, Lilja H. Alpha1-antichymotrypsin production in PSA-producing cells is common in prostate cancer but rare in benign prostatic hyperplasia. Urology 1994 ; 43 : 427-34.
16. Bjaartell A, Abrahamsson P, Bjork T, Sant'agnese A, Matikainen M, Lilja H. Production of alpha-1-antichymotrypsin by PSA-containing cells of human prostate epithelium. Urology 1993 ; 42 : 502-10.
17. Riegman PH, Vlietstra RJ, Suurmejer LC. Characterization of the human kallikrein locus. Genomics 1992 ; 14 : 6-11.
18. Viola MV, Fromowitz F, Oravez S, Deb S, Finkel G, Lundy J, Hand P, Thor A, Schlom J. Expression of ras oncogene p21 in prostate cancer. N Eng J Med 1986 ; 314 : 133-7.
19. Fleming WH, Hamel A, MacDonald R, Ramsey E, Pettigrew NM, Johnston B, Dodd JG, Matusik RJ. Expression of the c-myc protooncogene in human prostatic carcinoma and benign prostate hyperplasia. Cancer Res 1986 ; 46 : 1535-8.
20. Al-abadi H, Nagel R. Nuclear DNA analysis : the relevance of ploidy, DNA heterogeneity and phases of the cell cycle in 329 patients with prostatic carcinoma. Urol Int 1990 ; 45 : 350-5.
21. Vihko P. Prostate-specific antigen and human glandular kallikrein. Eur Urol 1995 ; 27(suppl 2) : 4.
22. Carrell R, Travis J. α1-ontitrypsin and the serine; variation and countervariation. TIBS 1985 ; 10 : 20-4.
23. Stein B, Peterson RO, Vangore S, Kendall AR. Immunoperoxidase localization of prostate-specific antigen. Am J Surg Pathol 1982 ; 6 : 553-7.
24. Abrahamson PA, Lilja H, Falkmer S, Wadstrom LB. Immunohistochemical distribution of the three predominant secretory proteins in the parenchyma of hyperplastic and neoplastic prostate glands. Prostate 1988 ; 12 : 39-46.
25. Epstein JI. PSA and PAP as immunohistochemical markers in prostate cancer. Urol Clin Nor Am 1993 ; 20 : 757-70.
26. Tomita T, Dalton T, Kwok S, Lee S, Nobel M, Chiga M. Profile of postatic-specific antigen in prostate carcinoma. Mod Pathol 1993 ; 6 : 259-64.
27. Maygarden SJ. Applications of immunohistochemistry to the diagnosis and prognostication of prostate carcinoma and prostatic intraepithelial neoplasia. Pathol Ann 1994 ; 29 : 303-20.
28. Bostwick DG. Prostate-specific antigen and pathology of the prostate. Eur Urol 1995 ; 27 (suppl 2) : 5.
29. McNeal JE. Morphogenesis of prostatic carcinoma. Cancer 1965 ; 18 : 1659-66.
30. McNeal JE, Reese JH, Redwine EA, Freiha FS, Stamey TA. Cribriform adenocarcinoma of the prostate. Cancer 1986 ; 58 : 1714-9.