-
1
-
-
2642522640
-
Genetic transformation of mouse embryos by microinjection of purified DNA
-
Gordon, J. W., Scangos, G. A., Plotkin, D. J., Barbosa, J. A., and Ruddle, F. H. (1980) Genetic transformation of mouse embryos by microinjection of purified DNA. Proc. Natl. Acad. Sci. USA 77, 7380-7384.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 7380-7384
-
-
Gordon, J.W.1
Scangos, G.A.2
Plotkin, D.J.3
Barbosa, J.A.4
Ruddle, F.H.5
-
2
-
-
0019859395
-
Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs
-
Brinster, R. L., Chen, H. Y., Trumbauer, M. E., Senear, A. W., Warren, R., and Palmiter, R. D. (1981) Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell 27, 223-231.
-
(1981)
Cell
, vol.27
, pp. 223-231
-
-
Brinster, R.L.1
Chen, H.Y.2
Trumbauer, M.E.3
Senear, A.W.4
Warren, R.5
Palmiter, R.D.6
-
3
-
-
0019855228
-
Introduction of a rabbit β-globin gene into the mouse germ line
-
Costantini, F. and Lacy, E. (1981) Introduction of a rabbit β-globin gene into the mouse germ line. Nature (Lond.) 294, 92-94.
-
(1981)
Nature (Lond.)
, vol.294
, pp. 92-94
-
-
Costantini, F.1
Lacy, E.2
-
4
-
-
0019790422
-
The human β-globin gene and a functional viral thymidine kinase gene in developing mice
-
Wagner, E. F., Stewart, T. A., and Mintz, B. (1981) The human β-globin gene and a functional viral thymidine kinase gene in developing mice. Proc. Natl. Acad. Sci. USA 78, 5016-5020.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 5016-5020
-
-
Wagner, E.F.1
Stewart, T.A.2
Mintz, B.3
-
5
-
-
0000051454
-
Microinjection of a rabbit β-globin gene into zygotes and its subsequent expression in adult mice and their off-spring
-
Wagner, T. E., Hoppe, P. C., Jollick, J. D., Scholl, D. R., Hodinka, R. L., and Gault, J. B. (1981) Microinjection of a rabbit β-globin gene into zygotes and its subsequent expression in adult mice and their off-spring. Proc. Natl. Acad. Sci. USA 78, 6376-6380.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 6376-6380
-
-
Wagner, T.E.1
Hoppe, P.C.2
Jollick, J.D.3
Scholl, D.R.4
Hodinka, R.L.5
Gault, J.B.6
-
6
-
-
0020470466
-
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes
-
Palmiter, R. D., Brinster, R. L., Hammer, R. E., Trumbauer, M. E., Rosenfield, M. G., Birnberg, N. C., and Evans, R. M. (1982) Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature (Lond.) 300, 611-615.
-
(1982)
Nature (Lond.)
, vol.300
, pp. 611-615
-
-
Palmiter, R.D.1
Brinster, R.L.2
Hammer, R.E.3
Trumbauer, M.E.4
Rosenfield, M.G.5
Birnberg, N.C.6
Evans, R.M.7
-
7
-
-
0021930664
-
Production of transgenic rabbits, sheep and pigs by microinjection
-
Hammer, R. E., Pursel, V. G., Rexroad, C. E., Wall, R. J., Bolt, D. J., Ebert, K. M., Palmiter, R. D., and Brinster, R. L. (1985) Production of transgenic rabbits, sheep and pigs by microinjection. Nature (Lond.) 315, 680-683.
-
(1985)
Nature (Lond.)
, vol.315
, pp. 680-683
-
-
Hammer, R.E.1
Pursel, V.G.2
Rexroad, C.E.3
Wall, R.J.4
Bolt, D.J.5
Ebert, K.M.6
Palmiter, R.D.7
Brinster, R.L.8
-
8
-
-
0024326699
-
Gene transfer experiments in cattle
-
Roschlau, K., Rommel, P., Andreewa, L., Zackel, M., Roshlau, D., Zackel, B., Schwerin, M., Huhn, R., and Gazarjan, K. G. (1989) Gene transfer experiments in cattle. J. Reprod. Fertil. Suppl. 38, 153-160.
-
(1989)
J. Reprod. Fertil. Suppl.
, vol.38
, pp. 153-160
-
-
Roschlau, K.1
Rommel, P.2
Andreewa, L.3
Zackel, M.4
Roshlau, D.5
Zackel, B.6
Schwerin, M.7
Huhn, R.8
Gazarjan, K.G.9
-
9
-
-
0023669148
-
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene
-
Palmiter, R. D., Behringer, R. R., Quaife, C. J., Maxwell, F., Maxwell, I. H., and Brinster, R. L. (1987) Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell 50, 435-443.
-
(1987)
Cell
, vol.50
, pp. 435-443
-
-
Palmiter, R.D.1
Behringer, R.R.2
Quaife, C.J.3
Maxwell, F.4
Maxwell, I.H.5
Brinster, R.L.6
-
10
-
-
0003799070
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Hogan, B., Beddington, R., Constantini, F., and Lacy, E. (1994) Manipulating the Mouse Embryo, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1994)
Manipulating the Mouse Embryo, 2nd Ed.
-
-
Hogan, B.1
Beddington, R.2
Constantini, F.3
Lacy, E.4
-
11
-
-
0028466229
-
Insertional mutagenesis in transgenic mice
-
Rijkers, T., Peetz, A., and Ruther, U. (1994) Insertional mutagenesis in transgenic mice. Transgenic Res. 3, 203-215.
-
(1994)
Transgenic Res.
, vol.3
, pp. 203-215
-
-
Rijkers, T.1
Peetz, A.2
Ruther, U.3
-
12
-
-
0029163860
-
Targeting the mouse genome: A compendium of knockouts (part I)
-
Brandon, E. P., Idzerda, R. L., and McKnight, G. S. (1995) Targeting the mouse genome: a compendium of knockouts (part I). Curr. Biol. 5, 625-630.
-
(1995)
Curr. Biol.
, vol.5
, pp. 625-630
-
-
Brandon, E.P.1
Idzerda, R.L.2
McKnight, G.S.3
-
13
-
-
0029328313
-
Targeting the mouse genome: A compendium of knockouts (part II)
-
Brandon, E. P., Idzerda, R. L., and McKnight, G. S. (1995) Targeting the mouse genome: a compendium of knockouts (part II). Curr. Biol. 5, 758-761.
-
(1995)
Curr. Biol.
, vol.5
, pp. 758-761
-
-
Brandon, E.P.1
Idzerda, R.L.2
McKnight, G.S.3
-
14
-
-
0029347193
-
Targeting the mouse genome: A compendium of knockouts (part III)
-
Brandon, E. P., Idzerda, R. L., and McKnight, G. S. (1995) Targeting the mouse genome: a compendium of knockouts (part III). Curr. Biol. 5, 873-881.
-
(1995)
Curr. Biol.
, vol.5
, pp. 873-881
-
-
Brandon, E.P.1
Idzerda, R.L.2
McKnight, G.S.3
-
15
-
-
0027131730
-
The identification of new genes: Gene trapping in transgenic mice
-
Skarnes, W. C. (1993) The identification of new genes: gene trapping in transgenic mice. Curr. Opinion Biotech. 4, 684-689.
-
(1993)
Curr. Opinion Biotech.
, vol.4
, pp. 684-689
-
-
Skarnes, W.C.1
-
16
-
-
0026523256
-
Embryonic Stem Cells and homologous recombination
-
Fung-Leung, W. and Mak, T. W. (1992) Embryonic Stem Cells and homologous recombination. Curr. Opinion Immunol. 4, 189-194.
-
(1992)
Curr. Opinion Immunol.
, vol.4
, pp. 189-194
-
-
Fung-Leung, W.1
Mak, T.W.2
-
17
-
-
0027425074
-
Gene targeting technology for creating transgenic models of lymphopoiesis
-
Huang, M. T. F. (1993) Gene targeting technology for creating transgenic models of lymphopoiesis. Lab. Anim. Sci. 43, 156-159.
-
(1993)
Lab. Anim. Sci.
, vol.43
, pp. 156-159
-
-
Huang, M.T.F.1
-
18
-
-
0028236876
-
Transgenic and knockout models for studying diseases of the immune system
-
Viney, J. L. (1994) Transgenic and knockout models for studying diseases of the immune system. Curr. Opinion Genet. Dev. 4, 461-465.
-
(1994)
Curr. Opinion Genet. Dev.
, vol.4
, pp. 461-465
-
-
Viney, J.L.1
-
19
-
-
0027146498
-
Transgenic approaches to cancer biology
-
Clarke, A. R. (1993) Transgenic approaches to cancer biology. Curr. Opinion Biotech. 4, 699-704.
-
(1993)
Curr. Opinion Biotech.
, vol.4
, pp. 699-704
-
-
Clarke, A.R.1
-
20
-
-
0028829684
-
New models of lymphoma in transgenic mice
-
Seldrin, D. C. (1995) New models of lymphoma in transgenic mice. Curr. Opinion Immunol. 7, 665-673.
-
(1995)
Curr. Opinion Immunol.
, vol.7
, pp. 665-673
-
-
Seldrin, D.C.1
-
21
-
-
0025906674
-
Transgenic models for haemopoietic malignancies
-
Adams, J. M. and Cory, S. (1991) Transgenic models for haemopoietic malignancies. Biochim. Biophys. Acta 1072, 9-31.
-
(1991)
Biochim. Biophys. Acta
, vol.1072
, pp. 9-31
-
-
Adams, J.M.1
Cory, S.2
-
22
-
-
0025820233
-
Transgenic oncogene mice
-
Cardiff, R. D., Sinn, E., Muller, W., and Leder, P. (1991) Transgenic oncogene mice. Am. J. Pathol. 139, 495-501.
-
(1991)
Am. J. Pathol.
, vol.139
, pp. 495-501
-
-
Cardiff, R.D.1
Sinn, E.2
Muller, W.3
Leder, P.4
-
23
-
-
0028376385
-
Molecular dissection of multi-stage tumorigenesis in transgenic mice
-
Christofori, G. and Hanahan, D. (1994) Molecular dissection of multi-stage tumorigenesis in transgenic mice. Semin. Cancer Biol. 5, 3-12.
-
(1994)
Semin. Cancer Biol.
, vol.5
, pp. 3-12
-
-
Christofori, G.1
Hanahan, D.2
-
24
-
-
0028376506
-
Identification and analysis of tumor suppressor genes using transgenic mouse models
-
Matzuk, M. and Bradley A. (1994) Identification and analysis of tumor suppressor genes using transgenic mouse models. Semin. Cancer Biol. 5, 37-45.
-
(1994)
Semin. Cancer Biol.
, vol.5
, pp. 37-45
-
-
Matzuk, M.1
Bradley, A.2
-
25
-
-
0028355079
-
Transgenic and knockout mice: Models of neurological disease
-
Aguzzi, A., Brandner, S., Sure, U., Rüedi, D., and Isenmann, S. (1994) Transgenic and knockout mice: models of neurological disease. Brain Pathol. 4, 3-20.
-
(1994)
Brain Pathol.
, vol.4
, pp. 3-20
-
-
Aguzzi, A.1
Brandner, S.2
Sure, U.3
Rüedi, D.4
Isenmann, S.5
-
26
-
-
0030131960
-
Transgenic animals and gonadotrophins
-
Markkula, M. and Huhtaniemi, I. (1996) Transgenic animals and gonadotrophins. Rev. Reprod. 1, 97-106.
-
(1996)
Rev. Reprod.
, vol.1
, pp. 97-106
-
-
Markkula, M.1
Huhtaniemi, I.2
-
27
-
-
0027419042
-
Transgenic strategies in reproductive endocrinology
-
Kelley, K. M., Johnson, T. R., Gwatkin, R. B. L., Ilan, J., and Ilan, J. (1993) Transgenic strategies in reproductive endocrinology. Mol. Reprod. Dev. 34, 337-347.
-
(1993)
Mol. Reprod. Dev.
, vol.34
, pp. 337-347
-
-
Kelley, K.M.1
Johnson, T.R.2
Gwatkin, R.B.L.3
Ilan, J.4
Ilan, J.5
-
28
-
-
0024457750
-
Animal models of human disease
-
Pattengale, P. K., Stewart, T. A., Leder, A., Sinn, E., Muller, W., Tepler, I., Schmidt, E., and Leder, P. (1989) Animal models of human disease. Am. J. Pathol. 135, 39-61.
-
(1989)
Am. J. Pathol.
, vol.135
, pp. 39-61
-
-
Pattengale, P.K.1
Stewart, T.A.2
Leder, A.3
Sinn, E.4
Muller, W.5
Tepler, I.6
Schmidt, E.7
Leder, P.8
-
29
-
-
0027654089
-
Transgenic animals as models for human disease - Report of an EC study group
-
Lathe, R. and Mullins, J. J. (1993) Transgenic animals as models for human disease - report of an EC study group. Transgenic Res. 2, 286-299.
-
(1993)
Transgenic Res.
, vol.2
, pp. 286-299
-
-
Lathe, R.1
Mullins, J.J.2
-
30
-
-
0028264246
-
Evolving concepts in molecular pathology
-
Kappel, C. A., Bieberich, C. J., and Jay, G. (1994) Evolving concepts in molecular pathology. FASEB J. 8, 583-592.
-
(1994)
FASEB J.
, vol.8
, pp. 583-592
-
-
Kappel, C.A.1
Bieberich, C.J.2
Jay, G.3
-
31
-
-
0001305936
-
Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs
-
Brinster, R. L., Chen, H. Y., Trumbauer, M. E., Yagle, M. K., and Palmiter, R. D. (1985) Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proc. Natl. Acad. Sci. USA 82, 4438-4442.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 4438-4442
-
-
Brinster, R.L.1
Chen, H.Y.2
Trumbauer, M.E.3
Yagle, M.K.4
Palmiter, R.D.5
-
32
-
-
0023891119
-
Gene transfer into sheep
-
Simons, P., Wilmut, I., Clark, J., Archibald, A. L., Bishop, J. O., and Lathe, R. (1988) Gene transfer into sheep. Biotechnology 6, 179-183.
-
(1988)
Biotechnology
, vol.6
, pp. 179-183
-
-
Simons, P.1
Wilmut, I.2
Clark, J.3
Archibald, A.L.4
Bishop, J.O.5
Lathe, R.6
-
33
-
-
0014964654
-
RNA-dependent DNA polymerase in virions of RNA tumour viruses
-
Baltimore, D., (1970) RNA-dependent DNA polymerase in virions of RNA tumour viruses. Nature (Lond.) 226, 1209-1211.
-
(1970)
Nature (Lond.)
, vol.226
, pp. 1209-1211
-
-
Baltimore, D.1
-
34
-
-
0016764976
-
Infection of preimplantation mouse embryos and of newborn mice with leukemia virus: Tissue distribution of viral DNA and RNA and leukemogenesis in the adult animal
-
Jaenisch, R., Fan, H., and Croker, B. (1975) Infection of preimplantation mouse embryos and of newborn mice with leukemia virus: tissue distribution of viral DNA and RNA and leukemogenesis in the adult animal. Proc. Natl. Acad. Sci. USA 72, 4008-4012.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 4008-4012
-
-
Jaenisch, R.1
Fan, H.2
Croker, B.3
-
35
-
-
0242568295
-
Germ line integration and mendelian transmission of the exogenous Moloney Leukemia Virus
-
Jaenisch, R. (1976) Germ line integration and mendelian transmission of the exogenous Moloney Leukemia Virus. Proc. Natl. Acad. Sci. USA 73, 1260-1264.
-
(1976)
Proc. Natl. Acad. Sci. USA
, vol.73
, pp. 1260-1264
-
-
Jaenisch, R.1
-
36
-
-
0023064459
-
Research and potential clinical applications of retroviral vectors
-
Donehower, L. A. (1987) Research and potential clinical applications of retroviral vectors. Prog. Med. Virol. 34, 1-32.
-
(1987)
Prog. Med. Virol.
, vol.34
, pp. 1-32
-
-
Donehower, L.A.1
-
37
-
-
0010498843
-
Efficient insertion of genes into the mouse germ line via retroviral vectors
-
Van der Putten, H., Botteri, F. M., Miller, A. D., Rosenfield, M. G., Fan, H., Evans, R. M., and Verma, I. M. (1985) Efficient insertion of genes into the mouse germ line via retroviral vectors. Proc. Natl. Acad. Sci. USA 82, 6148-6152.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 6148-6152
-
-
Van Der Putten, H.1
Botteri, F.M.2
Miller, A.D.3
Rosenfield, M.G.4
Fan, H.5
Evans, R.M.6
Verma, I.M.7
-
38
-
-
0022337148
-
Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector
-
Husar, D., Balling, R., Kothary, R., Magli, M. C., Hozumi, N., Rossant, J., and Bernstein, A. (1985) Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector. Proc. Natl. Acad. Sci. USA 82, 8587-8591.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 8587-8591
-
-
Husar, D.1
Balling, R.2
Kothary, R.3
Magli, M.C.4
Hozumi, N.5
Rossant, J.6
Bernstein, A.7
-
39
-
-
1842674657
-
Germline transmission of exogenous genes in the chicken following microinjection of embryos with a non-replicating retrovirus vector
-
Church, R. B., ed., Wiley-Liss, New York
-
Bosselman, R. A., Hsu, R.-Y., Boggs, T., Hu, S., Bruszewski, J., Martin, F., Jacobsen, F., Nicolson, M., Schultz, J. A., Semon, K. M., Rishell, W., and Stewart, R. G. (1990) Germline transmission of exogenous genes in the chicken following microinjection of embryos with a non-replicating retrovirus vector, in Transgenic Models in Medicine and Agriculture (Church, R. B., ed.), Wiley-Liss, New York, pp. 21-32.
-
(1990)
Transgenic Models in Medicine and Agriculture
, pp. 21-32
-
-
Bosselman, R.A.1
Hsu, R.-Y.2
Boggs, T.3
Hu, S.4
Bruszewski, J.5
Martin, F.6
Jacobsen, F.7
Nicolson, M.8
Schultz, J.A.9
Semon, K.M.10
Rishell, W.11
Stewart, R.G.12
-
40
-
-
0027600635
-
Transgenesis in chickens
-
Perry, M. M. and Sang, H. M. (1993) Transgenesis in chickens. Transgenic Res. 2, 125-133.
-
(1993)
Transgenic Res.
, vol.2
, pp. 125-133
-
-
Perry, M.M.1
Sang, H.M.2
-
41
-
-
1842674658
-
Production of transgenic lamb foetuses by sub-zonal injection of Feline Leukaemia Virus
-
Church, R. B., ed., Wiley-Liss, New York
-
Harvey, M. J. A., Hettle, S. J. H., Cameron, E. R., Johnston, C. S., and Onions, D. E. (1990) Production of transgenic lamb foetuses by sub-zonal injection of Feline Leukaemia Virus, in Transgenic Models in Medicine and Agriculture (Church, R. B., ed.), Wiley-Liss, New York, pp. 11-19.
-
(1990)
Transgenic Models in Medicine and Agriculture
, pp. 11-19
-
-
Harvey, M.J.A.1
Hettle, S.J.H.2
Cameron, E.R.3
Johnston, C.S.4
Onions, D.E.5
-
42
-
-
0027284738
-
Gene transfer in bovine blastocysts using replication-defective retroviral vectors packaged with Gibbon ape leukaemia virus envelopes
-
Kim, T., Leibfried-Rutledge, M. L., and First, N. L. (1993) Gene transfer in bovine blastocysts using replication-defective retroviral vectors packaged with Gibbon ape leukaemia virus envelopes. Mol. Reprod. Dev. 35, 105-113.
-
(1993)
Mol. Reprod. Dev.
, vol.35
, pp. 105-113
-
-
Kim, T.1
Leibfried-Rutledge, M.L.2
First, N.L.3
-
43
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans, M. J. and Kaufman, M. H. (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature (Lond.) 292, 154-156.
-
(1981)
Nature (Lond.)
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
44
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin, G. R. (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA 78, 7634-7638.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 7634-7638
-
-
Martin, G.R.1
-
45
-
-
0021358883
-
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
-
Bradley, A., Evans, M., Kaufman, M. H., and Robertson, E. (1984) Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature (Lond.) 309, 255,256.
-
(1984)
Nature (Lond.)
, vol.309
, pp. 255
-
-
Bradley, A.1
Evans, M.2
Kaufman, M.H.3
Robertson, E.4
-
46
-
-
0022389290
-
Insertion of DNA sequences into the human chromosome β-globin locus by homologous recombination
-
Smithies, O., Gregg, R. G., Boggs, S. S., Koralewski, M. A., and Kucherlapati, R. S. (1985) Insertion of DNA sequences into the human chromosome β-globin locus by homologous recombination. Nature (Lond.) 317, 230-234.
-
(1985)
Nature (Lond.)
, vol.317
, pp. 230-234
-
-
Smithies, O.1
Gregg, R.G.2
Boggs, S.S.3
Koralewski, M.A.4
Kucherlapati, R.S.5
-
47
-
-
0022542596
-
High frequency targeting of genes to specific sites in the mammalian genome
-
Thomas, K. R., Folger, K. R., and Capecchi, M. R. (1986) High frequency targeting of genes to specific sites in the mammalian genome. Cell 44, 419-428.
-
(1986)
Cell
, vol.44
, pp. 419-428
-
-
Thomas, K.R.1
Folger, K.R.2
Capecchi, M.R.3
-
48
-
-
0024296027
-
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes
-
Mansour, S. L., Thomas, K. R., and Capecchi, M. R. (1988) Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature (Lond.) 336, 348-352.
-
(1988)
Nature (Lond.)
, vol.336
, pp. 348-352
-
-
Mansour, S.L.1
Thomas, K.R.2
Capecchi, M.R.3
-
49
-
-
0024494423
-
Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells
-
Thompson, S., Clarke, A. R., Pow, A. M., Hooper, M. L., and Melton, D. W. (1989) Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells. Cell 56, 313-321.
-
(1989)
Cell
, vol.56
, pp. 313-321
-
-
Thompson, S.1
Clarke, A.R.2
Pow, A.M.3
Hooper, M.L.4
Melton, D.W.5
-
50
-
-
0024328536
-
Altering the genome by homologous recombination
-
Capecchi, M. R. (1989) Altering the genome by homologous recombination. Science 244, 1288-1292.
-
(1989)
Science
, vol.244
, pp. 1288-1292
-
-
Capecchi, M.R.1
-
51
-
-
0028724380
-
Impact of gene targeting on medicine
-
Thomas, K. R. (1994) Impact of gene targeting on medicine. Mol. Genet. Med. 4, 153-178.
-
(1994)
Mol. Genet. Med.
, vol.4
, pp. 153-178
-
-
Thomas, K.R.1
-
52
-
-
0022553076
-
Pancreatic expression of human insulin gene in transgenic mice
-
Bucchini, D., Ripoche, M. A., Stinnakre, M. G., Desbois, P., Lores, P., Monthioux, E., Absil, J., Lepesant, J. A., Pictet, R., and Jami, J. (1986) Pancreatic expression of human insulin gene in transgenic mice. Proc. Natl. Acad. Sci. USA 83, 2511-2515.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 2511-2515
-
-
Bucchini, D.1
Ripoche, M.A.2
Stinnakre, M.G.3
Desbois, P.4
Lores, P.5
Monthioux, E.6
Absil, J.7
Lepesant, J.A.8
Pictet, R.9
Jami, J.10
-
53
-
-
0021961473
-
Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice
-
Ornitz, D. M., Palmiter, R. D., Hammer, R. E., Brinster, R. L., Swift, G. H., and MacDonald, R. J. (1985) Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice. Nature (Lond.) 313, 600-602.
-
(1985)
Nature (Lond.)
, vol.313
, pp. 600-602
-
-
Ornitz, D.M.1
Palmiter, R.D.2
Hammer, R.E.3
Brinster, R.L.4
Swift, G.H.5
MacDonald, R.J.6
-
54
-
-
0022351502
-
Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice
-
Overbeek, P. A., Chepelinsky, A. B., Khillan, J. S., Piatigorsky, J., and Westphal, H. (1985) Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice. Proc. Natl. Acad. Sci. USA 82, 7815-7819.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 7815-7819
-
-
Overbeek, P.A.1
Chepelinsky, A.B.2
Khillan, J.S.3
Piatigorsky, J.4
Westphal, H.5
-
55
-
-
0022755320
-
Tissue specific and developmentally regulated expression of a chimeric actin-globin gene in transgenic mice
-
Shani, M. (1986) Tissue specific and developmentally regulated expression of a chimeric actin-globin gene in transgenic mice. Mol. Cell. Biol. 6, 2624-2631.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 2624-2631
-
-
Shani, M.1
-
56
-
-
0022261216
-
Developmental regulation of alpha-fetoprotein genes in transgenic mice
-
Krumlauf, R., Hammer, R. E., Tilghman, S. M., and Brinster, R. L. (1985) Developmental regulation of alpha-fetoprotein genes in transgenic mice. Mol. Cell. Biol. 5, 1639-1648.
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 1639-1648
-
-
Krumlauf, R.1
Hammer, R.E.2
Tilghman, S.M.3
Brinster, R.L.4
-
57
-
-
0022600521
-
An embryonic pattern of expression of a human fetal globin gene in transgenic mice
-
Chada, K., Magram, J., and Costantini, F. (1986) An embryonic pattern of expression of a human fetal globin gene in transgenic mice. Nature (Lond.) 319, 685-689.
-
(1986)
Nature (Lond.)
, vol.319
, pp. 685-689
-
-
Chada, K.1
Magram, J.2
Costantini, F.3
-
58
-
-
0022497717
-
Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development
-
Leder, A., Pattengale, P. K., Kuo, A., Stewart, T. A., and Leder, P. (1986) Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development. Cell 45, 485-495.
-
(1986)
Cell
, vol.45
, pp. 485-495
-
-
Leder, A.1
Pattengale, P.K.2
Kuo, A.3
Stewart, T.A.4
Leder, P.5
-
60
-
-
0024300166
-
Transgenes as probes for active chromosomal domains in mouse development
-
Allen, N. D., Cran, D. G., Barton, S. C., Hettle, S., Reik, W., and Surani, M. A. (1988) Transgenes as probes for active chromosomal domains in mouse development. Nature (Lond.) 333, 852-855.
-
(1988)
Nature (Lond.)
, vol.333
, pp. 852-855
-
-
Allen, N.D.1
Cran, D.G.2
Barton, S.C.3
Hettle, S.4
Reik, W.5
Surani, M.A.6
-
61
-
-
0001372225
-
Introns increase transcriptional efficiency in transgenic mice
-
Brinster, R. L., Allen, J. M., Behringer, R. R., Gelinas, R. E., and Palmiter, R. D. (1988) Introns increase transcriptional efficiency in transgenic mice. Proc. Natl. Acad. Sci. USA 85, 836-840.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 836-840
-
-
Brinster, R.L.1
Allen, J.M.2
Behringer, R.R.3
Gelinas, R.E.4
Palmiter, R.D.5
-
62
-
-
0023663887
-
Position-independent, high-level expression of the human β-globin gene in transgenic mice
-
Grosveld, F., van Assendelft, G. B., Greaves, D. R., and Kollias, G. (1987) Position-independent, high-level expression of the human β-globin gene in transgenic mice. Cell, 51, 975-985.
-
(1987)
Cell
, vol.51
, pp. 975-985
-
-
Grosveld, F.1
Van Assendelft, G.B.2
Greaves, D.R.3
Kollias, G.4
-
63
-
-
0024025869
-
The structure of the human CD2 gene and its expression in transgenic mice
-
Lang, G., Wotton, D., Owen, M. J., Sewell, W. A., Brown, M. H., Mason, D. Y., Crumpton, M. J., and Kioussis, D. (1988) The structure of the human CD2 gene and its expression in transgenic mice. EMBO J. 7, 1675-1682.
-
(1988)
EMBO J.
, vol.7
, pp. 1675-1682
-
-
Lang, G.1
Wotton, D.2
Owen, M.J.3
Sewell, W.A.4
Brown, M.H.5
Mason, D.Y.6
Crumpton, M.J.7
Kioussis, D.8
-
64
-
-
0024490115
-
High-level erythroid expression of human α-globin genes in transgenic mice
-
Ryan T. M., Behringer, R. R., Townes, T. M., Palmiter, R. D., and Brinster, R. L. (1989) High-level erythroid expression of human α-globin genes in transgenic mice. Proc. Natl. Acad. Sci. USA 86, 37-41.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 37-41
-
-
Ryan, T.M.1
Behringer, R.R.2
Townes, T.M.3
Palmiter, R.D.4
Brinster, R.L.5
-
65
-
-
0025145628
-
Tissue specific and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice
-
Bonifer, C., Vidal, M., Grosveld, F., and Sippel, A. E. (1990) Tissue specific and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice. EMBO J. 9, 2843-2848.
-
(1990)
EMBO J.
, vol.9
, pp. 2843-2848
-
-
Bonifer, C.1
Vidal, M.2
Grosveld, F.3
Sippel, A.E.4
-
66
-
-
0027182948
-
Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice
-
Palmiter, R. D., Sandgren, E. P., Koeller, D. M., and Brinster, R. L. (1993) Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice. Mol. Cell. Biol. 13, 5266-5275.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 5266-5275
-
-
Palmiter, R.D.1
Sandgren, E.P.2
Koeller, D.M.3
Brinster, R.L.4
-
67
-
-
0028334542
-
A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice
-
Ganss, R., Montoliu, L., Monaghan, A. P., and Schutz, G. (1994) A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice. EMBO J. 13, 3083-3093.
-
(1994)
EMBO J.
, vol.13
, pp. 3083-3093
-
-
Ganss, R.1
Montoliu, L.2
Monaghan, A.P.3
Schutz, G.4
-
68
-
-
0027416353
-
Transcriptional regulation of multigene loci: Multilevel control
-
Dillon, N. and Grosveld, F. (1993) Transcriptional regulation of multigene loci: multilevel control. Trends Genet. 9, 134-137.
-
(1993)
Trends Genet.
, vol.9
, pp. 134-137
-
-
Dillon, N.1
Grosveld, F.2
-
69
-
-
0027924720
-
The regulation of human globin gene switching
-
Grosveld, F., Antoniou, M., Berry, M., deBoer, E., Dillon, N., Ellis, J., Fraser, P., Hanscombe, O., Hurst, J., Imam, A., Lindenbaum, M., Philipsen, S., Pruzina, S., Strouboulis, J., Raguz-Bolognesi, S., and Talbot, D. (1993) The regulation of human globin gene switching. Phil. Trans. R. Soc. Lond. B Biol. Sci. 339, 183-191.
-
(1993)
Phil. Trans. R. Soc. Lond. B Biol. Sci.
, vol.339
, pp. 183-191
-
-
Grosveld, F.1
Antoniou, M.2
Berry, M.3
DeBoer, E.4
Dillon, N.5
Ellis, J.6
Fraser, P.7
Hanscombe, O.8
Hurst, J.9
Imam, A.10
Lindenbaum, M.11
Philipsen, S.12
Pruzina, S.13
Strouboulis, J.14
Raguz-Bolognesi, S.15
Talbot, D.16
-
70
-
-
0027485678
-
Alu sequence involvement in transcriptional insulation of the keratin 18 gene in transgenic mice
-
Thorey, I. S., Cecena, G., Reynolds, W., and Oshima, R. G. (1993) Alu sequence involvement in transcriptional insulation of the keratin 18 gene in transgenic mice. Mol. Cell. Biol. 13, 6742-6751.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6742-6751
-
-
Thorey, I.S.1
Cecena, G.2
Reynolds, W.3
Oshima, R.G.4
-
71
-
-
0028988485
-
Position-independent transgene expression mediated by boundary elements from the apolipoprotein B chromatin domain
-
Kalos, M. and Fournier, R. E. K. (1995) Position-independent transgene expression mediated by boundary elements from the apolipoprotein B chromatin domain. Mol. Cell. Biol. 15, 198-207.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 198-207
-
-
Kalos, M.1
Fournier, R.E.K.2
-
72
-
-
0028290476
-
Scaffold attachment regions stimulate HSP70. 1 expression in mouse preimplantation embryos but not in differentiated tissues
-
Thompson, E. M., Christians, E., Stinnakre, M., and Renard, J. (1994) Scaffold attachment regions stimulate HSP70. 1 expression in mouse preimplantation embryos but not in differentiated tissues. Mol. Cell. Biol. 14, 4694-4703.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4694-4703
-
-
Thompson, E.M.1
Christians, E.2
Stinnakre, M.3
Renard, J.4
-
73
-
-
0027306750
-
Sar-dependent mobilisation of histone H1 by HMG-I/Y in vitro: Is enriched in H1-depleted chromatin
-
Zhao, K., Käs, E., Gonzalez, E., and Laemmli, U. K. (1993) Sar-dependent mobilisation of histone H1 by HMG-I/Y in vitro: is enriched in H1-depleted chromatin. EMBO J. 12, 3237-3247.
-
(1993)
EMBO J.
, vol.12
, pp. 3237-3247
-
-
Zhao, K.1
Käs, E.2
Gonzalez, E.3
Laemmli, U.K.4
-
74
-
-
0028795722
-
Dissecting a locus control region: Facilitation of enhancer function by extended enhancer flanking sequences
-
Aronow, B. J., Ebert, C. A., Valerius, M. T., Potter, S. S., Wiginton, D. A., Witte, D. P., and Hutton, J. J. (1995) Dissecting a locus control region: facilitation of enhancer function by extended enhancer flanking sequences. Mol. Cell. Biol. 15, 1123-1135.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1123-1135
-
-
Aronow, B.J.1
Ebert, C.A.2
Valerius, M.T.3
Potter, S.S.4
Wiginton, D.A.5
Witte, D.P.6
Hutton, J.J.7
-
75
-
-
0029059215
-
Position-dependent variegation of globin transgene expression in mice
-
Robertson, G., Garrick, D., Wu, W., Kearns, M., Martin, D., and Whitelaw, E. (1995) Position-dependent variegation of globin transgene expression in mice. Proc. Natl. Acad. Sci. USA 92, 5371-5375.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5371-5375
-
-
Robertson, G.1
Garrick, D.2
Wu, W.3
Kearns, M.4
Martin, D.5
Whitelaw, E.6
-
76
-
-
0029912235
-
Locus control region function and heterochromatin-induced position effect variegation
-
Festenstein, R., Tolaini, M., Corbella, P., Mamalaki, C., Parrington, J., Fox, M., Miliou, A., Jones, M., and Kioussis, D. (1996) Locus control region function and heterochromatin-induced position effect variegation. Science 271, 1123-1125.
-
(1996)
Science
, vol.271
, pp. 1123-1125
-
-
Festenstein, R.1
Tolaini, M.2
Corbella, P.3
Mamalaki, C.4
Parrington, J.5
Fox, M.6
Miliou, A.7
Jones, M.8
Kioussis, D.9
-
77
-
-
0028847640
-
Random activation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element
-
Elliott, J. I., Festenstein, R., Tolaini, M., and Kioussis, D. (1995) Random activation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element. EMBO J. 14, 575-584.
-
(1995)
EMBO J.
, vol.14
, pp. 575-584
-
-
Elliott, J.I.1
Festenstein, R.2
Tolaini, M.3
Kioussis, D.4
-
78
-
-
0027408985
-
Germ-line transmission and expression of a human-derived yeast artificial chromosome
-
Jakobovits, A., Moore, A. L., Green, L. L., Vergara, G. J., Maynard-Currie, C. E., Austin, H. A., and Klapholz, S. (1993) Germ-line transmission and expression of a human-derived yeast artificial chromosome. Nature (Lond.) 362, 255-258.
-
(1993)
Nature (Lond.)
, vol.362
, pp. 255-258
-
-
Jakobovits, A.1
Moore, A.L.2
Green, L.L.3
Vergara, G.J.4
Maynard-Currie, C.E.5
Austin, H.A.6
Klapholz, S.7
-
79
-
-
0028715755
-
Germ line transmission of yeast artificial chromosomes in transgenic mice
-
Montoliu, L., Schedl, A., Kelsey, G., Zentgraf, H., Lichter, P., and Schütz, G. (1994) Germ line transmission of yeast artificial chromosomes in transgenic mice. Reprod. Fertil. Dev. 6, 577-584.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 577-584
-
-
Montoliu, L.1
Schedl, A.2
Kelsey, G.3
Zentgraf, H.4
Lichter, P.5
Schütz, G.6
-
80
-
-
0027464687
-
A yeast artificial chromosome covering the tyrosine gene confers copy number dependent expression in transgenic mice
-
Schedl, A., Montoliu, L., Kelsey, G., and Schütz, G. (1993) A yeast artificial chromosome covering the tyrosine gene confers copy number dependent expression in transgenic mice. Nature (Lond.) 362, 258-261.
-
(1993)
Nature (Lond.)
, vol.362
, pp. 258-261
-
-
Schedl, A.1
Montoliu, L.2
Kelsey, G.3
Schütz, G.4
-
81
-
-
0027261194
-
Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human α-globin locus display proper developmental control of human globin genes
-
Peterson, K. R., Clegg, C. H., Huxley, C., Josephson, B. M., Haugen, H. S., Furukawa, T., and Stamatoyannopoulos, G. (1993) Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human α-globin locus display proper developmental control of human globin genes. Proc. Natl. Acad. Sci. USA 90, 7593-7597.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7593-7597
-
-
Peterson, K.R.1
Clegg, C.H.2
Huxley, C.3
Josephson, B.M.4
Haugen, H.S.5
Furukawa, T.6
Stamatoyannopoulos, G.7
-
82
-
-
0029558513
-
Synergistic regulation of human beta-globin gene switching by locus control elements HS3 and HS4
-
Bungert, J., Dave, U., Lim, K. C., Liew, K. H., Shavit, J. A., Liu, Q., and Engel, J. D. (1995) Synergistic regulation of human beta-globin gene switching by locus control elements HS3 and HS4. Gene. Dev. 9, 3083-3096.
-
(1995)
Gene. Dev.
, vol.9
, pp. 3083-3096
-
-
Bungert, J.1
Dave, U.2
Lim, K.C.3
Liew, K.H.4
Shavit, J.A.5
Liu, Q.6
Engel, J.D.7
-
83
-
-
0029073038
-
Use of yeast artificial chromosomes (YACs) in studies of mammalian development: Production of beta-globin locus YAC mice carrying human globin developmental mutants
-
Peterson, K. R., Li, Q. L., Clegg, C. H., Furukawa, T., Navas, P. A., Norton, E. J., Kimbrough, T. G., and Stamatoyannopoulos, G. (1995) Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants. Proc. Natl. Acad. Sci. USA 92, 5655-5659.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5655-5659
-
-
Peterson, K.R.1
Li, Q.L.2
Clegg, C.H.3
Furukawa, T.4
Navas, P.A.5
Norton, E.J.6
Kimbrough, T.G.7
Stamatoyannopoulos, G.8
-
84
-
-
0028150583
-
Insertion of a pathogenic mutation into a yeast artificial chromosome containing the human amyloid precursor protein gene
-
Duff, K., McGuigan, A., Huxley, C., Schulz, F., and Hardy, J. (1994) Insertion of a pathogenic mutation into a yeast artificial chromosome containing the human amyloid precursor protein gene. Gene Ther. 1, 70-75.
-
(1994)
Gene Ther.
, vol.1
, pp. 70-75
-
-
Duff, K.1
McGuigan, A.2
Huxley, C.3
Schulz, F.4
Hardy, J.5
-
85
-
-
0028800213
-
Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a)
-
McCormick, S. P., Ng, J. K., Taylor, S., Flynn, L. M., Hammer, R. E., and Young, S. G. (1995) Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a). Proc. Natl. Acad. Sci. USA 92, 10,147-10,151.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10147-10151
-
-
McCormick, S.P.1
Ng, J.K.2
Taylor, S.3
Flynn, L.M.4
Hammer, R.E.5
Young, S.G.6
-
86
-
-
0027210623
-
Germ line transmission of a yeast artificial chromosome spanning the murine alpha 1(1) collagen locus
-
Strauss, W. M., Dausman, J., Beard, C., Johnson, C., Lawrence, J. B., and Jaenisch, R. (1993) Germ line transmission of a yeast artificial chromosome spanning the murine alpha 1(1) collagen locus. Science 259, 1904-1907.
-
(1993)
Science
, vol.259
, pp. 1904-1907
-
-
Strauss, W.M.1
Dausman, J.2
Beard, C.3
Johnson, C.4
Lawrence, J.B.5
Jaenisch, R.6
-
87
-
-
0030221606
-
Strategies for expressing human antibody repertoires in transgenic mice
-
Brüggemann, M. and Neuberger, M. S. (1996) Strategies for expressing human antibody repertoires in transgenic mice. Immunol. Today 17, 391-397.
-
(1996)
Immunol. Today
, vol.17
, pp. 391-397
-
-
Brüggemann, M.1
Neuberger, M.S.2
-
88
-
-
0028715914
-
Site-specific transgene insertion: An approach
-
Wigley, P., Becker, C., Beltrame, J., Blake, T., Crocker, L., Harrison, S., Lyons, I., McKenzie, Z., Tearle, R., Crawford, R., and Robins, A. (1994) Site-specific transgene insertion: an approach. Reprod. Fertil. Dev. 6, 585-588.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 585-588
-
-
Wigley, P.1
Becker, C.2
Beltrame, J.3
Blake, T.4
Crocker, L.5
Harrison, S.6
Lyons, I.7
McKenzie, Z.8
Tearle, R.9
Crawford, R.10
Robins, A.11
-
89
-
-
0029786931
-
Single-copy transgenic mice with chosen-site integration
-
Bronson, S. K., Plaehn, E. G., Kluckman, K. D., Hagaman, J. R., Maeda, N., and Smithies, O. (1996) Single-copy transgenic mice with chosen-site integration. Proc. Natl. Acad. Sci. USA 93, 9067-9072.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9067-9072
-
-
Bronson, S.K.1
Plaehn, E.G.2
Kluckman, K.D.3
Hagaman, J.R.4
Maeda, N.5
Smithies, O.6
-
90
-
-
0029059790
-
Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
-
Hanks, M., Wurst, W., Anson-Cartwright, L., Auerbach, A. B., and Joyner, A. L. (1995) Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269, 679-682.
-
(1995)
Science
, vol.269
, pp. 679-682
-
-
Hanks, M.1
Wurst, W.2
Anson-Cartwright, L.3
Auerbach, A.B.4
Joyner, A.L.5
-
91
-
-
0028938747
-
Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene
-
Efrat, S., Fusco DeMane, D., Lemberg, H., al Emran, O., and Wang, X. (1995) Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene. Proc. Natl. Acad. Sci. USA 92, 3576-3580.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3576-3580
-
-
Efrat, S.1
Fusco DeMane, D.2
Lemberg, H.3
Al Emran, O.4
Wang, X.5
-
92
-
-
0026939055
-
Inducible vectors for expression in mammalian cells
-
Yarranton, G. T. (1992) Inducible vectors for expression in mammalian cells. Curr. Opinion Biotechnol. 3, 506-511.
-
(1992)
Curr. Opinion Biotechnol.
, vol.3
, pp. 506-511
-
-
Yarranton, G.T.1
-
93
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen, M. and Bujard, H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89, 5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
94
-
-
0028071115
-
Temporal control of gene expression in transgenic mice by a tetracycline responsive promoter
-
Furth, P. A., St. Onge, L., Böger, H., Gruss, P., Gossen, M., Kistner, A., Bujard, H., and Hennighausen, L. (1994) Temporal control of gene expression in transgenic mice by a tetracycline responsive promoter. Proc. Natl. Acad. Sci. USA 91, 9302-9306.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9302-9306
-
-
Furth, P.A.1
St. Onge, L.2
Böger, H.3
Gruss, P.4
Gossen, M.5
Kistner, A.6
Bujard, H.7
Hennighausen, L.8
-
95
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
Gossen, M., Freundlieb, S., Bender, G., Müller, G., Hillen, W., and Bujard, H. (1995) Transcriptional activation by tetracyclines in mammalian cells. Science 268, 1766-1769.
-
(1995)
Science
, vol.268
, pp. 1766-1769
-
-
Gossen, M.1
Freundlieb, S.2
Bender, G.3
Müller, G.4
Hillen, W.5
Bujard, H.6
-
96
-
-
0026638820
-
Targeted oncogene activation by site-specific recombination in transgenic mice
-
Lakso, M., Sauer, B., Mosinger, B., Lee, E. J., Manning, R. W., Yu, S.-H., Mulder, K. L., and Westphal, H. (1992) Targeted oncogene activation by site-specific recombination in transgenic mice. Proc. Natl. Acad. Sci. USA 89, 6232-6236.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6232-6236
-
-
Lakso, M.1
Sauer, B.2
Mosinger, B.3
Lee, E.J.4
Manning, R.W.5
Yu, S.-H.6
Mulder, K.L.7
Westphal, H.8
-
97
-
-
0029155706
-
Inducible gene targeting in mice
-
Kühn, R., Schwenk, F., Aguet, M., and Rajewsky, K. (1995) Inducible gene targeting in mice. Science 269, 1427-1429.
-
(1995)
Science
, vol.269
, pp. 1427-1429
-
-
Kühn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
98
-
-
0028961591
-
Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis
-
Mountford, P. S. and Smith, A. G. (1995) Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis. Trends. Genet. 11, 179-184.
-
(1995)
Trends. Genet.
, vol.11
, pp. 179-184
-
-
Mountford, P.S.1
Smith, A.G.2
-
99
-
-
0025997947
-
The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos
-
Ghattas, I. R., Sanes, J. R., and Majors, J. E. (1991) The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos. Mol Cell. Biol. 11, 5848-5859.
-
(1991)
Mol Cell. Biol.
, vol.11
, pp. 5848-5859
-
-
Ghattas, I.R.1
Sanes, J.R.2
Majors, J.E.3
-
100
-
-
0028701437
-
Progress and emerging problems in livestock transgenesis: A summary perspective
-
Seamark, R. F. (1994) Progress and emerging problems in livestock transgenesis: a summary perspective. Reprod. Fertil. Dev. 6, 653-657.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 653-657
-
-
Seamark, R.F.1
-
101
-
-
0028701299
-
Challenges and progress in the production of transgenic cattle
-
Eyestone, W. H. (1994) Challenges and progress in the production of transgenic cattle. Reprod. Fertil. Dev. 6, 647-652.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 647-652
-
-
Eyestone, W.H.1
-
102
-
-
0028243503
-
Production of fetuses from totipotent cultured bovine inner cell mass cells
-
Sims, M. M. and First, N. L. (1994) Production of fetuses from totipotent cultured bovine inner cell mass cells. Proc. Natl. Acad. Sci. USA 90, 6143-6147.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6143-6147
-
-
Sims, M.M.1
First, N.L.2
-
103
-
-
0028715754
-
System of production of calves from cultured bovine embryonic cells
-
First, N. L., Sims, M. M., Park, S. P., and Kent-First, M. J. (1994) System of production of calves from cultured bovine embryonic cells. Reprod. Fertil. Dev. 6, 553-562.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 553-562
-
-
First, N.L.1
Sims, M.M.2
Park, S.P.3
Kent-First, M.J.4
-
104
-
-
0028700593
-
Development and validation of swine embryonic stem cells: A review
-
Wheeler, M. B. (1994) Development and validation of swine embryonic stem cells: a review. Reprod. Fertil. Dev. 6, 563-568.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 563-568
-
-
Wheeler, M.B.1
-
105
-
-
0029967424
-
Sheep cloned by nuclear transfer from a cultured cell line
-
Campbell, K. H. S., McWhir, J., Ritchie, W. A., and Wilmut, I. (1996) Sheep cloned by nuclear transfer from a cultured cell line. Nature (Lond.) 380, 64-66.
-
(1996)
Nature (Lond.)
, vol.380
, pp. 64-66
-
-
Campbell, K.H.S.1
McWhir, J.2
Ritchie, W.A.3
Wilmut, I.4
-
106
-
-
0028700594
-
Transgenic livestock as genetic models of human disease
-
Petters, R. M. (1994) Transgenic livestock as genetic models of human disease. Reprod. Fertil. Dev. 6, 643-645.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 643-645
-
-
Petters, R.M.1
-
107
-
-
0028701436
-
Transgenic strategies to increase disease resistance in livestock
-
Müller, M. and Brem, G. (1994) Transgenic strategies to increase disease resistance in livestock. Reprod. Fertil. Dev. 6, 605-613.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 605-613
-
-
Müller, M.1
Brem, G.2
-
108
-
-
0028605651
-
Strategies for production of pharmaceutical proteins in milk
-
Wilmut, I. and Whitelaw, C. B. A. (1994) Strategies for production of pharmaceutical proteins in milk. Reprod. Fertil. Dev. 6, 625-630.
-
(1994)
Reprod. Fertil. Dev.
, vol.6
, pp. 625-630
-
-
Wilmut, I.1
Whitelaw, C.B.A.2
-
109
-
-
14744276106
-
High level expression of active human α-1 antitrypsin in the milk of transgenic sheep
-
Wright, G., Carver, A., Cottom, D., Reeves, D., Scott, A., Simons, P., Wilmut, I., Garner, I., and Coleman, A. (1991) High level expression of active human α-1 antitrypsin in the milk of transgenic sheep. Bio-technology (NY) 9, 831-834.
-
(1991)
Bio-technology (NY)
, vol.9
, pp. 831-834
-
-
Wright, G.1
Carver, A.2
Cottom, D.3
Reeves, D.4
Scott, A.5
Simons, P.6
Wilmut, I.7
Garner, I.8
Coleman, A.9
-
110
-
-
0029033071
-
Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury
-
McCurry, K. R., Kooyman, D. L., Alvarado, C. G., Cotterell, A. H., Martin, M. J., Logan, J. S., and Platt, J. L. (1995) Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury. Nat. Med. 1, 423-427.
-
(1995)
Nat. Med.
, vol.1
, pp. 423-427
-
-
McCurry, K.R.1
Kooyman, D.L.2
Alvarado, C.G.3
Cotterell, A.H.4
Martin, M.J.5
Logan, J.S.6
Platt, J.L.7
-
111
-
-
0029068597
-
The generation of transgenic pigs as potential organ donors for humans
-
Cozzi E. and White, D. J. (1995) The generation of transgenic pigs as potential organ donors for humans. Nat. Med. 1, 964-966.
-
(1995)
Nat. Med.
, vol.1
, pp. 964-966
-
-
Cozzi, E.1
White, D.J.2
-
112
-
-
0030221794
-
Transplantation of discordant xenografts: A challenge revisited
-
Parker, W., Saadi, S., Lin, S. S., Holzknecht, Z. E., Bustos, M., and Platt, J. L. (1996) Transplantation of discordant xenografts: a challenge revisited. Immunol. Today 17, 373-378.
-
(1996)
Immunol. Today
, vol.17
, pp. 373-378
-
-
Parker, W.1
Saadi, S.2
Lin, S.S.3
Holzknecht, Z.E.4
Bustos, M.5
Platt, J.L.6
-
113
-
-
0030221816
-
Delayed xenograft rejection
-
Bach, F. H., Winkler, H., Ferran, C., Hancock, W. W., and Robson, S. C. (1996) Delayed xenograft rejection. Immunol. Today 17, 379-384.
-
(1996)
Immunol. Today
, vol.17
, pp. 379-384
-
-
Bach, F.H.1
Winkler, H.2
Ferran, C.3
Hancock, W.W.4
Robson, S.C.5
|