Regulation of Uterine Immune Function during the Estrous Cycle and in Response to Infectious Bacteria in Sheep

Journal of Animal Science

Volumn 75, Issue 6, 1997, Pages 1621-1632

  Ramadan, A A ^a,b   Johnson III, G L ^a   Lewis, G S ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b ANIMAL PRODUCTION RESEARCH INSTITUTE   (Egypt)

Author keywords

Immune Response; Infectious; Lymphocyte Transformation; Sheep; Uterus

Indexed keywords

ACTINOMYCES; ARCANOBACTERIUM PYOGENES; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; OVIS; OVIS ARIES;

ESTROGEN; PROGESTERONE; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA;

ACTINOMYCES; ACTINOMYCOSIS; ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOLOGY; DRUG EFFECT; ENTEROBACTER INFECTION; EOSINOPHIL; ESCHERICHIA COLI; ESTRUS; FEMALE; FOLLICULAR PHASE; IMMUNOLOGY; LUTEAL PHASE; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; METABOLISM; MONOCYTE; NEUTROPHIL; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SHEEP; SHEEP DISEASE; TIME; UTERUS; UTERUS DISEASE;

ACTINOMYCES; ACTINOMYCOSIS; ANIMALS; DINOPROST; DINOPROSTONE; EOSINOPHILS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESTROGENS; ESTRUS; FEMALE; FOLLICULAR PHASE; LUTEAL PHASE; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MONOCYTES; NEUTROPHILS; PROGESTERONE; SHEEP; SHEEP DISEASES; TIME FACTORS; UTERINE DISEASES; UTERUS;

EID: 0031156959     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/1997.7561621x     Document Type: Article

References (49)

1. Arthur, G. H., D. E. Noakes, and H. Pearson. 1989a. Infectious forms of infertility in cattle. In: G. H. Arthur, D. E. Noakes, and H. Pearson (Ed.) Veterinary Reproduction and Obstetrics. p 384. Baillière Tindall, Philadelphia, PA.
2. Arthur, G. H., D. E. Noakes, and H. Pearson. 1989b. Veterinary Reproduction and Obstetrics (6th Ed.). Baillière Tindall, Philadelphia, PA.
3. Benoit, A. M., and R. A. Dailey. 1991. Catheterization of the caudal vena cava via lateral saphenous vein in the ewe, cow, and gilt: An alternative to utero-ovarian and medial coccygeal vein catheters. J. Anim. Sci. 69:2971-2979.
4. Black, W. G., L. C. Ulberg, H. E. Kidder, J. Simon, S. H. McNutt, and L. E. Casida. 1953. Inflammatory response of the bovine endometrium. Am. J. Vet. Res. 14:179-183.
5. Brinsfield, T. H., H. W. Hawk, and E. C. Leffel. 1963. Control by ovarian hormones of the inflammatory response in the sheep uterus. J. Reprod. Fertil. 6:79-86.
6. Brinsfield, T. H., H. W. Hawk, and E. C. Leffel. 1967. Control by ovarian status of induced leukocytic responses in the sheep uterus. Am. J. Vet. Res. 28:1723-1725.
7. Brinsfield, T. H., H. W. Hawk, and H. F. Righter. 1964. Interaction of progesterone and oestradiol on induced leukocytic emigration in the sheep uterus. J. Reprod. Fertil. 8:293-296.
8. Burrells, C., and P. W. Wells. 1977. In vitro stimulation of ovine lymphocytes by various mitogens. Res. Vet. Sci. 23:84-86.
9. Cai, T. Q., P. G. Weston, L. A. Lund, B. Brodie, D. J. McKenna, and W. C. Wagner. 1994. Association between neutrophil functions and periparturient disorders in cows. Am. J. Vet. Res. 55: 934-943.
10. Carson, R. L., D. F. Wolfe, P. H. Klesius, R. J. Kemppainen, and C. M. Scanlan. 1988. The effects of ovarian hormones and ACTH on uterine defense to Corynebacterium pyogenes in cows. Theriogenology 30:91-97.
11. Cochran, W. G. and G. M. Cox. 1957. Experimental Design (2nd Ed.). John Wiley & Sons, New York.
12. 2α metabolite concentrations in postpartum dairy cows. Theriogenology 41:413-421.
13. 2α metabolite concentrations in postpartum beef cows. J. Anim. Sci. 70: 3158-3162.
14. 2α in plasma. Prostaglandins 43:321-330.
15. Eley, D. S., W. W. Thatcher, H. H. Head, R. J. Collier, and C. J. Wilcox. 1981. Periparturient endocrine changes of conceptus and maternal units in Jersey cows bred for milk yield. J. Dairy Sci. 64:296-311.
16. 2α, progesterone, and estrogens in ovarian-intact ewes around the time of luteolysis? Prostaglandins 47: 171-187.
17. 2α in hysterectomized ewes. Biol. Reprod. 16:571-579.
18. 2α during blockade of luteolysis in pigs after human chorionic gonadotropin treatment. J. Anim. Sci. 57:993-1000.
19. Hawk, H. W., T. H. Brinsfield, and H. F. Righter. 1963. Control by ovarian hormones of vascular permeability in normal and experimentally-infected sheep uteri. J. Reprod. Fertil. 6:71-77.
20. Hawk, H. W., T. H. Brinsfield, G. D. Turner, G. W. Whitmore, and M. A. Norcross. 1964. Effect of ovarian status on induced acute inflammatory responses in cattle uteri. Am. J. Vet. Res. 25: 362-366.
21. Hawk, H. W., G. D. Turner, and J. F. Sykes. 1961. Variation in the inflammatory response and bactericidal activity of the sheep uterus during the estrous cycle. Am. J. Vet. Res. 22:689-692.
22. Hoedemaker, M., L. A. Lund, and W. C. Wagner. 1992a. Function of neutrophils and chemoattractant properties of fetal placental tissue during the last month of pregnancy in cows. Am. J. Vet. Res. 53:1524-1529.
23. Hoedemaker, M., L. A. Lund, and W. C. Wagner. 1992b. Influence of arachidonic acid metabolites and steroids on function of bovine polymorphonuclear neutrophils. Am. J. Vet. Res. 53:1534-1539.
24. Lander Chacin, M. F., P. J. Hansen, and M. Drost. 1990. Effects of stage of the estrous cycle and steroid treatment on uterine immunoglobulin content and polymorphonuclear leukocytes in cattle. Theriogenology 34:1169-1184.
25. Lewis, G. S. 1997. Uterine health and disorders. J. Dairy Sci. 80: 984-994.
26. 2α. Anim. Reprod. Sci. 18:183-197.
27. 2 and their relationship to luteal function in early pregnant ewes. J. Anim. Sci. 47: 1314-1323.
28. Lewis, G. S., W. W. Thatcher, E. L. Bliss, M. Drost, and R. J. Collier. 1984. Effects of heat stress during pregnancy on postpartum reproductive changes in Holstein cows. J. Anim. Sci. 58: 174-186.
29. Lewis, G. S., and R. A. Waterman. 1985. Metabolism of arachidonic acid in vitro by ovine conceptuses recovered during early pregnancy. Prostaglandins 30:263-283.
30. Liu, W-J., and P. J. Hansen. 1993. Effect of the progesterone-induced serpin-like proteins of the sheep endometrium on natural-killer cells activity in sheep and mice. Biol. Reprod. 49: 1008-1014.
31. Lydyard, P., and C. E. Grossi. 1993. Cells involved in immune responses. In: I. M. Roitt, J. Brostoff, and D. K. Male (Ed.) Immunology (3rd Ed.). p 2.1. Mosby-Year Book Europe Ltd., London.
32. Male, D. K. 1993. Cell migration and inflammation. In: I. M. Roitt, J. Brostoff, and D. K. Male (Ed.) Immunology (3rd Ed.). p 13.1. Mosby-Year Book Europe Ltd., London.
33. 4 on neutrophil functional responses. Scand. J. Immunol. 33: 357-363.
34. Robicsek, S. A., D. K. Blanchard, J. Y. Djeu, J. J. Krzanowski, A. Szentivanyi, and J. B. Polson. 1991. Multiple high-affinity cAMP-phosphodiesterases in human T-lymphocytes. Biochem. Pharmacol. 42:869-877.
35. 2 and cAMP inhibit lymphocyte activation and simultaneously promote IgE and IgG1 synthesis. J. Immunol. 149:2984-2991.
36. Roth, J. A., M. L. Kaeberle, and L. H. Appell. 1983. Association of increased estradiol and progesterone blood values with altered bovine polymorphonuclear leukocyte function. Am. J. Vet. Res. 44:247-253.
37. Rowson, L.E.A., G. E. Lamming, and R. M. Fry. 1953. The relationship between ovarian hormones and uterine infection. Vet. Rec. 65:335.
38. SAS. 1988. User's Guide. Statistics (Version 5 Ed.). SAS Inst. Inc., Cary, NC.
39. Schindler, D., G. S. Lewis, M. Rosenberg, A. Tadmor, N. Ezov, M. Ron, E. Aizinbud, and A. R. Lehrer. 1990. Vulvar electrical impedance in periparturient cows and its relationship to plasma progesterone, oestradiol-17β and PGFM. Anim. Reprod. SCi. 23:283-292.
40. Segerson, E. C., Jr. 1988. Suppression of interleukin-2-mediated T-lymphocyte blastogenesis by bovine uterine luminal protein. Biol. Reprod. 38:256-263.
41. Skopets, B., and P. J. Hansen. 1993. Identification of the predominant proteins in uterine fluids of unilaterally pregnant ewes that inhibit lymphocyte proliferation. Biol. Reprod. 49: 997-1007.
42. 2) and uterine involution in the cow. Theriogenology 36: 1071-1090.
43. Staples, L. D., I. R. Fleet, and R. B. Heap. 1982. Anatomy of the utero-ovarian lymphatic network and the composition of afferent lymph in relation to the establishment of pregnancy in the sheep and goat. J. Reprod. Fertil. 64:409-420.
44. Tizard, I. R. 1996. Veterinary Immunology: An Introduction (5th Ed.). W. B. Saunders Co., Philadelphia, PA.
45. Vaillier, D., R. Daculsi, N. Gualde, and J. H. Bezian. 1992. Effect of LTB4 on the inhibition of natural cytotoxic activity by PGE2. Cell. Immunol. 139:248-258.
46. Valitutti, S., M. Dessing, and A. Lanzavecchia. 1993. Role of cAMP in regulating cytotoxic T lymphocyte adhesion and motility. Eur. J. Immunol. 23:790-795.
47. 2α. Domest. Anim. Endocrinol. 13: 383-398.
48. Washburn, S. M., P. H. Klesius, V. K. Ganjam, and B. G. Brown. 1982. Effects of estrogen and progesterone on the phagocytic response of ovariectomized mares infected in utero with β-hemolytic streptococci. Am. J. Vet. Res. 43:1367-1370.
49. Watson, E. D., N. K. Diehl, and J. F. Evans. 1990. Antibody response in the bovine genital tract to intrauterine infusion of Actinomyces pyogenes. Res. Vet. Sci. 48:70-75.