IV. Molecular biology of S-layers

FEMS Microbiology Reviews

Volumn 20, Issue 1-2, 1997, Pages 47-98

  Bahl, Hubert ^a   Scholz, Holger ^b   Bayan, Nicolas ^c   Chami, Mohamed ^c   Leblon, Gérard ^c   Gulik Krzywicki, Thaddée ^c   Shechter, Emanuel ^c   Fouet, Agnés ^d   Mesnage, Stéphane ^d   Tosi Couture, Evelyne ^d   Gounon, Pierre ^d   Mock, Michèle ^d   De Macario, Everly Conway ^e   Macario, Alberto J L ^e   Fernández Herrero, Luis A ^f   Olabarría, Garbiñe ^f   Berenguer, José ^f   Blaser, Martin J ^g   Kuen, Beatrix ^b   Lubitz, Werner ^b   Sára, Margit ^h   Pouwels, Peter H ⁱ   Kolen, Carin P A M ^j   Boot, Hein J ^j   Palva, Airi ^k   Truppe, Michaela ^b   Howorka, Stephan ^b   Schroll, Gerhard ^b   Lechleitner, Sonja ^b   Resch, Stephanie ^b   more..

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

^c CNRS   (France)

^d INSTITUT PASTEUR   (France)

^e STATE UNIVERSITY OF NEW YORK   (United States)

^f UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^g VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

ⁱ TNO   (Netherlands)

^j UNIVERSITY OF AMSTERDAM   (Netherlands)

^k FINNISH FOREST RESEARCH INSTITUTE   (Finland)

more..

Author keywords

ABC transporter; Antigenic diversity; Bacillus anthracis; Bacillus stearothermophilus; Corynebacterium glutamicum; cspB gene; EAI protein; Gene regulation; Heterologous expression; Lactobacilli; Lactobacillus brevis; Methanogenic archaea; Methanosarcina mazei; Oxygen stress; PS2 protein; S layer; S layer gene; S layer protein; S layer structure function relationship; S layer variation; Sap protein; Sbs gene; SbsA SbsB fusion protein; Secretion of lactamase; SLH motif; Slp gene; SlpA gene; Thermus thermophilus

Indexed keywords

ABC TRANSPORTER; BACTERIAL PROTEIN; HYBRID PROTEIN; MESSENGER RNA; OXYGEN; RECOMBINANT PROTEIN; BACTERIAL ANTIGEN; OUTER MEMBRANE PROTEIN;

BACILLUS ANTHRACIS; BACTERIAL CELL WALL; CAMPYLOBACTER FETUS; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; GENE CONTROL; GEOBACILLUS STEAROTHERMOPHILUS; LACTOBACILLUS; METHANOBACTERIUM; MOLECULAR BIOLOGY; NONHUMAN; PROTEIN ANALYSIS; REVIEW; SEQUENCE HOMOLOGY; THERMUS THERMOPHILUS; AMINO ACID SEQUENCE; ANTIGENIC VARIATION; BACILLUS; BACTERIAL GENE; BACTERIUM; CELL MEMBRANE; CELL WALL; CHEMISTRY; CORYNEBACTERIUM; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHYSIOLOGY; ULTRASTRUCTURE;

ARCHAEA; BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); CAMPYLOBACTER FETUS; CORYNEBACTERIUM GLUTAMICUM; GEOBACILLUS STEAROTHERMOPHILUS; LACTOBACILLUS; LACTOBACILLUS BREVIS; METHANOBACTERIUM; METHANOSARCINA MAZEI; THERMUS THERMOPHILUS;

AMINO ACID SEQUENCE; ANTIGENIC VARIATION; ANTIGENS, BACTERIAL; ATP-BINDING CASSETTE TRANSPORTERS; BACILLUS; BACTERIA; BACTERIAL OUTER MEMBRANE PROTEINS; BASE SEQUENCE; CELL MEMBRANE; CELL WALL; CORYNEBACTERIUM; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; LACTOBACILLUS; MOLECULAR SEQUENCE DATA; THERMUS THERMOPHILUS;

EID: 0031155384     PISSN: 01686445     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-6445(97)00050-8     Document Type: Review

References (199)

1. Aggerbeck, L.P. and Gulik-Krzywicki, T. (1986) Studies of lipoproteins by freeze-fracture and etching electron microscopy. Methods Enzymol. 128, 457-472.
2. Richter, W., Hänel, F. and Hilliger, M. (1985) Freeze-fracture observations of Corynebacterium glutamicum: the occurrence of an outer membrane-like structure and the influence of temperature on the cytoplasmic membrane. J. Basic Microbiol. 25, 527-536.
3. Beveridge, T.J. and Graham, L.L. (1991) Surface layers of bacteria. Microbiol. Rev. 55, 684-705.
4. Messner, P. and Sleytr, U.B. (1992) Crystalline bacterial cell-surface layers. Adv. Microbiol. Physiol. 33, 213-275.
5. Chami, M., Bayan, N., Dedieu, J.-C., Leblon, G., Shechter, E. and Gulik-Krzywicki, T. (1995) Organization of the outer layers of the cell envelope of Corynebacterium glutamicum: a combined freeze-etch electron microscopy and biochemical study. Biol. Cell. 83, 219-229.
6. Luckevich, M.D. and Beveridge, T.J. (1989) Characterization of a dynamic S-layer on Bacillus thuringiensis. J. Bacteriol. 171, 6656-6667.
7. Yamada, H., Tsukagoshi, N. and Udaka, S. (1981) Morphological alterations of cell wall concomitant with protein release in a protein-producing bacterium, Bacillus brevis 47. J. Bacteriol. 148, 322-332.
8. Kawata, T. and Masuda, K. (1972) Extracellular crystalline lattice material of Corynebacterium diphtheriae revealed by electron microscopy. Jap. J. Microbiol. 16, 515-523.
9. Stewart, M. and Murray, R.G.E. (1982) Structure of the regular surface layer of Aquaspirillum serpens MW5. J. Bacteriol. 150, 348-357.
10. Beveridge, T.J. and Murray, R.G.E. (1976) Superficial cell-wall layers on Spirillum 'ordal' and their in vitro reassembly. Can. J. Microbiol. 22, 567-582.
11. Remsen, C.C., Valois, F.W. and Watson, S.W. (1970) Fine structure of the cytomembranes of Nitrosocystis oceanus. J. Bacteriol. 94, 422-433.
12. Austin, J.W. and Murray, R.G.E. (1990) Isolation and in vitro assembly of the components of the outer S-layer of Lampropedia hyalina. J. Bacteriol. 172, 3681-3689.
13. Baumeister, W., Karrenberg, F., Rachel, R., Engel, A., Ten Heggeler, B. and Saxton, W.O. (1982) The major cell envelope protein of Micrococcus radiodurans (R1): structural and chemical characterization. Eur. J. Biochem. 125, 535-544.
14. Mescher, M.F. and Strominger, J.L. (1976) Purification and characterization of a prokaryotic glycoprotein from the cell envelope of Halobacterium salinarium. J. Biol. Chem. 251, 2005-2014.
15. Küpcü, Z., März, L., Messner, P. and Sleytr, U.B. (1984) Evidence for the glycoprotein nature of the crystalline cell wall surface layer of Bacillus stearothermophilus strain NRS2004/3a. FEMS Lett. 173, 185-190.
16. Peyret, J.L., Bayan, N., Joliff, G., Gulik-Krzywicki, T., Mathieu, L., Shechter, E. and Leblon, G. (1993) Characterization of the cspB gene encoding PS2, an ordered surface layer protein in Corynebacterium glutamicum. Mol. Microbiol. 9, 97-109.
17. Blaser, M.J. and Gotschlich, E.C. (1990) Surface array protein of Campylobacter fetus cloning and gene structure. J. Biol. Chem. 265, 14529-14535.
18. Evenberg, D. and Lugtenberg, B. (1982) Cell surface of the fish pathogenic bacterium Aeromonas salmonicida: II. Purification and characterization of a major cell envelope protein related to autoagglutination, adhesion and virulence. Biochim. Biophys. Acta 684, 249-254.
19. Fujimoto, S., Takade, A., Amako, K. and Blaser, M.J. (1991) Correlation between molecular size of the surface array protein and morphology and antigenicity of the Campylobacter fetus S-layer. Infect. Immun. 59, 2017-2022.
20. Wang, E., Garcia, M.M., Blake, M.S., Pei, Z. and Blaser, M.J. (1993) Shift in S-layer protein expression responsible for antigenic variation in Campylobacter fetus. J. Bacteriol. 175, 4979-4984.
21. Liebl, W. and Sinskey, A.J. (1988) Molecular cloning and nucleotide sequence of a gene involved in the production of extracellular DNase by Corynebacterium glutamicum. In: Genetics and Biotechnology of Bacilli (Ganesan, A.T. and Hoch, J.A., Eds.), pp. 383-388. Academic Press, New York.
22. 2 terminal region of PS1 is similar to the Mycobacterium antigen 85 complex. Mol. Microbiol. 6, 2349-2362.
23. Ould, L.K. (1995) Sécrétion de protéines hétérologues chez les Corynébactéries productrices d'acides aminés. Thesis, Université de Paris XI, Paris.
24. Chami, M., Bayan, N., Peyret, J.L., Gulik-Krzywicki, T., Leblon, G. and Shechter, E. (1997) The S-layer protein of Corynebacterium glutamicum is anchored to the cell wall by its C-terminal hydrophobic domain. Mol. Microbiol. 23, 483-492.
25. Lupas, A., Engelhardt, H., Peters, J., Santarius, U., Volker, S. and Baumeister, W. (1994) Domain structure of the Acetogenium kiwi surface layer revealed by electron crystallography and sequence analysis. J. Bacteriol. 176, 1224-1233.
26. Olabarría, G., Carrascosa, J.L., De Pedro, M.A. and Berenguer, J. (1996) A conserved motif in S-layer proteins is involved in peptidoglycan binding in Thermus thermophilus. J. Bacteriol. 178, 4765-4772.
27. Yang, L., Pei, Z., Fujimoto, S. and Blaser, M.J. (1992) Reattachment of surface array proteins to Campylobacter fetus cells. J. Bacteriol. 174, 1258-1267.
28. Walker, S.G., Karunaratne, D.N., Ravenscroft, N. and Smit, J. (1994) Characterization of mutants of Caulobacter crescentus defective in surface attachment of the paracrystalline surface layer. J. Bacteriol. 176, 6312-6323.
29. Lechner, J. and Sumper, M. (1987) The primary structure of a procaryotic glycoprotein. J. Biol. Chem. 262, 9724-9729.
30. Sumper, M., Berg, E., Mengele, R. and Strobel, I. (1990) Primary structure and glycosylation of the S-layer protein of Haloferax volcanii. J. Bacteriol. 172, 7111-7118.
31. Carl, M., Dobson, M.E., Ching, W.-M. and Dasch, G.A. (1990) Characterization of the gene encoding the protective paracrystalline surface layer protein of Rickettsia prowazekii: presence of a truncated identical homolog in Rickettsia typhi. Proc. Natl. Acad. Sci. USA 87, 8237-8241.
32. Kessel, M., Wildhaber, I., Cohen, S. and Baumeister, W. (1988) Three-dimensional structure of the regular surface glycoprotein layer of Halobacterium volcanii from the dead sea. EMBO J. 7, 1549-1554.
33. Trias, J., Jarlier, V. and Benz, R. (1992) Porins in the cell wall of mycobacteria. Science 258, 1479-1481.
34. Niederweis, M., Maier, E., Lichtinger, T., Benz, R. and Krämer, R. (1995) Identification of channel-forming activity in the cell wall of Corynebacterium glutamicum. J. Bacteriol. 177, 5716-5718.
35. De Briel, D., Couderc, F., Riegel, P., Jehl, F. and Minck, R. (1992) High-performance liquid chromatography of coronomycolic acids as a tool in identification of Corynebacterium species and related organisms. J. Clin. Microbiol. 30, 1407-1417.
36. Kornberg, R.D. and Darst, S.A. (1991) Two-dimensional crystals of proteins on lipid layers. Curr. Opin. Struct. Biol. 1, 642-646.
37. Hastie, A.T. and Brinton, C.C. Jr. (1979) Specific interaction of the tetragonally arrayed protein layer of Bacillus sphaericus with its peptidoglycan sacculus. J. Bacteriol. 138, 1010-1021.
38. Thomas, S., Austin, J.W., McCubbin, W.D., Kay, C.M. and Trust, T.J. (1992) Roles of structural domains in the morphology and surface anchoring of the tetragonal paracrystalline array of Aeromonas hydrophila. J. Mol. Biol. 228, 652-661.
39. Nikaido, H. (1994) Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science 264, 382-388.
40. Brennan, P.J. and Nikaido, H. (1995) The envelope of mycobacteria. Annu. Rev. Biochem. 64, 29-63.
41. Mikesell, P., Ivins, B.E., Ristroph, J.D. and Dreier, T.M. (1983). Evidence for plasmid mediated toxin production in Bacillus anthracis. Infect. Immun. 39, 371-376.
42. Green, B.D., Battisti, L., Koehler, T.M., Thorne, C.B. and Ivins, B.E. (1985). Demonstration of a capsule plasmid in Bacillus anthracis. Infect. Immun. 49, 291-297.
43. Gerhardt, P. (1967) Cytology of Bacillus anthracis. Fed. Proc. 26, 1504-1517.
44. Holt, S.C. and Leadbetter, E.R. (1969) Comparative ultrastructure of selected aerobic spore-forming bacteria: a freeze-etching study. Bacteriol. Rev. 33, 346-378.
45. Sleytr, U.B., Messner, P., Pum, D. and Sára, M. (1993) Crystalline bacterial cell surface layers. Mol. Microbiol. 10, 911-916.
46. Etienne-Toumelin, I., Sirard, J.-C., Duflot, E., Mock, M. and Fouet, A. (1995) Characterization of the Bacillus anthracis S-layer: cloning and sequencing of the structural gene. J. Bacteriol. 177, 614-620.
47. [46a] Mesnage, S., Tosi-Couture, E., Mock, M., Gounon, P. and Fouet, A. (1997) Molecular characterization of the Bacillus anthracis main S-layer component; evidence that it is the major cell-associated antigen. Mol. Microbiol. 23, 1147-1155.
48. Adachi, T., Yamagata, H., Tsukagoshi, N. and Udaka, S. (1989) Multiple and tandemly arranged promoters of the cell wall protein gene operon in Bacillus brevis 47. J. Bacteriol. 171, 1010-1016.
49. Tummuru, M.K.R. and Blaser, M.J. (1993) Rearrangement of sapA homologs with conserved and variable regions in Campylobacter fetus. Proc. Natl. Acad. Sci. USA 90, 7265-7269.
50. Blaser, M.J., Wang, E., Tummuru, M.K.R., Washburn, R., Fujimoto, S. and Labigne, A. (1994) High frequency S-layer protein variation in Campylobacter fetus revealed by sap A mutagenesis. Mol. Microbiol. 14, 521-532.
51. Dworkin, J. and Blaser, M.J. (1996) Generation of Campylobacter fetus S-layer protein diversity utilizes a single promoter on an invertible DNA segment. Mol. Microbiol. 19, 1241-1253.
52. Moran, C.P.J. (1993) RNA polymerase and transcription factors. In: Bacillus subtilis and other Gram-positive Bacteria (Sonenshein, A.L., Hoch, J.A. and Losick, R., Eds.), pp. 653-667. American Society for Microbiology, Washington, DC.
53. Vellanoweth, R.L. and Rabinowitz, J.C. (1992) The influence of ribosome-binding-site elements on translational efficiency in Bacillus subtilis and Escherichia coli in vivo. Mol. Microbiol. 6. 1105-1114.
54. Simonen, M. and Palva I. (1993) Protein secretion in Bacillus species. Microbiol. Rev. 57, 109-137.
55. Lemaire, M., Ohayon, H., Gounon, P., Fujino, P. and Beguin, P. (1995) OlpB, a new outer layer protein of Clostridium thermocellum, and binding of its S-layer-like domains to components of the cell envelope. J. Bacteriol. 177, 2451-2459.
56. [54a] Zhu, X., McVeigh, R.R., Malathi, P. and Ghosh, B.K. (1996) The complete nucleotide sequence of the Bacillus licheniformis NM105 S-layer-encoding gene. Gene 173, 189-194.
57. Tang, M., Owens, K., Pietri, R., Zhu, X., McVeigh, R. and Ghosh, B.K. (1989) Cloning of the crystalline cell wall protein gene of Bacillus licheniformis NM 105. J. Bacteriol. 171, 6637-6648.
58. Troy, F.A. (1973) Chemistry and biosynthesis of the poly (γ-D-glutamyl) capsule in Bacillus licheniformis. Properties of the membrane mediated biosynthetic reaction. J. Biol. Chem. 248, 305-315.
59. Kist, M.L. and Murray, R.G.E. (1984) Components of the regular surface array of Aquaspirillum serpens MW5 and their assembly in vitro. J. Bacteriol. 157, 599-606.
60. Tsuboi, A., Uchihi, R., Tabata, R., Takahashi, Y., Hashiba, H., Sasaki, T., Yamagata, H., Tsukagoshi, N. and Udaka, S. (1986) Characterization of the genes coding for two major cell wall proteins from protein-producing Bacillus brevis 47: complete nucleotide sequence of the outer wall protein gene. J. Bacteriol. 168, 365-373.
61. Boot, H.J., Kolen, C.P.A.M. and Pouwels, P.H. (1996) Interchange of the active and silent S-layer protein genes of Lactobacillus acidophilus by inversion of the chromosomal segment. Mol. Microbiol. 21, 799-809.
62. Olabarría, G., Fernandez-Herrero, L.A., Carrascosa, J.L. and Berenguer, J. (1996) SlpM, gene coding for an 'S-layer-like array' overexpressed in S-layer mutants of Thermus thermophilus HB8. J. Bacteriol. 178, 357-365.
63. Sára, M., Kuen, B., Mayer, H.F., Mandl, F., Schuster, K.C. and Sleytr, U.B. (1996) Dynamics in oxygen-induced changes in S-layer protein synthesis from Bacillus stearothermophilus PV72 and the S-layer-deficient variant T5 in continuous culture and studies of the cell wall composition. J. Bacteriol. 178, 2108-2117.
64. Takumi, K., Koga, T., Oka, T. and Endo, Y. (1991) Self-assembly, adhesion, and chemical properties of tetragonally arrayed S-layer proteins of Clostridium. J. Gen. Appl. Microbiol. 37, 455-465.
65. Ezzell, J.W. and Abshire, T.G. (1988) Immunological analysis of cell-associated antigens Bacillus anthracis. Infect. Immun. 56, 349-356.
66. Macario, A.J.L. and Conway de Macario, E. (1985) Monoclonal antibodies of predefined molecular specificity for identification and classification of methanogens and for probing their ecologic niches. In: Monoclonal Antibodies Against Bacteria (Macario, A.J.L. and Conway de Macario, E., Eds.), Vol. II, pp. 213-247. Academic Press, Orlando, FL.
67. Beveridge, T.J. (1994) Bacterial S-layers. Curr. Opin. Struct. Biol. 4, 204-212.
68. Konisky, J., Lynn, D., Hoppert, M., Mayer, F. and Haney, P. (1994) Identification of Methanococcus voltae S-layer structural gene. J. Bacteriol. 176, 1790-1792.
69. Conway de Macario, E., Macario, A.J.L., Miller, T. and Wolin, M.J. (1987) Antigenic diversity of methanogenic bacteria from intestinal tracts of animals. Syst. Appl. Microbiol. 9, 210-213.
70. Miller, T.L., Wolin, M.J., Conway de Macario, E. and Macario, A.J.L. (1982) Isolation Methanobrevibacter smithii from human feces. Appl. Environ. Microbiol. 43, 227-232.
71. 2 only after adaptation. Curr. Mirobiol. 23, 165-173.
72. Belay, N., Johnson, R., Rajagopal, B.S., Conway de Macario, E. and Daniels, L. (1988) Methanogenic bacteria from human dental plaque. Appl. Environ. Microbiol. 54, 600-603.
73. Belay, N., Mukhopadhyay, B., Conway de Macario, E., Galask, R. and Daniels, L. (1990) Methanogenic bacteria in human vaginal samples. J. Clin. Microbiol. 28, 1666-1668.
74. Cairó, J., Macario, A.J.L., Bardulet, M., Conway de Macario, E. and Paris, J.M. (1991) Psychrophilic ecosystems of interest for wastewater treatment: Microbiologic and immunologic elucidation of the methanogenic flora. Syst. Appl. Microbiol. 14, 85-92.
75. Franzmann, P.D., Springer, N., Ludwig, W., Conway de Macario, E. and Rohde, M. (1992) A methanogenic archaeon from Ace Lake, Antarctica: Methanococcoides burtonii sp. nov. Syst. Appl. Microbiol. 15, 573-581.
76. 2S-tolerant methylotrophic methanogens, coenriched with their oxidative and sulphate reducing bacterial consorts, are all new immunotypes and probably include new taxa. Marine Ecol. Prog. Ser. 95, 81-89.
77. Blotevogel, K.-H., Gahl-Janßen, R., Jannsen, S., Fischer, U., Pilz, F., Auling, G., Macario, A.J.L. and Tindall, B.J. (1991) Isolation and characterization of a novel mesophilic, fresh-water methanogen from river sediment Methanoculleus oldenburgensis sp. nov. Arch. Microbiol. 157, 54-59.
78. Kotelnikova, S., Pedersen, K. and Macario, A.J.L. (1997) Methanobacterium subterranium sp. nov., a new alcalophilic, eurythermic, and halotolerant methanogen isolated from deep granitic groundwater (submitted).
79. Jain, M.K., Thompson, T.E., Conway de Macario, E. and Zeikus, J.G. (1987) Speciation of Methanobacterium strain ivanov as Methanobacterium ivanovii, sp. nov. Syst. Appl. Microbiol. 9, 77-82.
80. Kim, B.-Y., Conway de Macario, E., Nölling, J. and Daniels, L. (1996) Isolation and characterization of a copper-resistant methanogen from a copper-mining soil sample. Appl. Environ. Microbiol. 62, 2629-2635.
81. Zellner, G., Bleicher, K., Braun, E., Kneifel, H., Tindall, B.J., Conway de Macario, E. and Winter, J. (1989) Characterization of a new mesophilic, secondary alcohol-utilizing methanogen, Methanobacterium palustre spec. nov. from a peat bog. Arch. Microbiol. 151, 1-9.
82. Fielding, E.R., Archer, D.B., Conway de Macario, E. and Macario, A.J.L. (1988) Isolation and characterization of methanogenic bacteria from landfills. Appl. Environ. Microbiol. 54, 835-836.
83. Macario, A.J.L. and Conway de Macario, E. (1988) Quantitative immunologic analysis of the methanogenic flora of digestors reveals a considerable diversity. Appl. Environ. Microbiol. 54, 79-86.
84. Macario, A.J.L., Earle, J.F.K., Chynoweth, D.P. and Conway de Macario, E. (1989) Distinctive patterns of methanogenic flora determined with antibody probes in anaerobic digestors of different characteristics operated under controlled conditions. Syst. Appl. Microbiol. 12, 216-222.
85. Zellner, G., Alten, C., Stackebrandt, E., Conway de Macario, E. and Winter, J. (1987) Isolation and characterization of Methanocorpusculum parvum, gen. nov., spec. nov., a new tungsten requiring, coccoid methanogen. Arch. Microbiol. 147, 13-20.
86. Zellner, G., Stackebrandt, E., Messner, P., Tindall, B.J., Conway de Macario, E. Kneifel, H., Sleytr, U.B. and Winter, J. (1989) Methanocorpusculaceae fam. nov., represented by Methanocorpusculum parvum, Methanocorpusculum sinense spec. nov. and Methanocorpusculum bavaricum spec. nov. Arch. Microbiol. 151, 381-390.
87. Conway de Macario, E., Macario, A.J.L. and Pastini, A. (1985) The superficial antigenic mosaic of Methanobrevibacter smithii: Identification of determinants and isolates by monoclonal antibodies. Arch. Microbiol. 142, 311-316.
88. Conway de Macario, E., Macario, A.J.L., and Magariños, M.C., König, H. and Kandler, O. (1983) Dissecting the antigenic mosaic of the archaebacterium Methanobacterium thermoautotrophicum by monoclonal antibodies of defined molecular specificity. Proc. Natl. Acad. Sci. USA 80, 6346-6350.
89. Conway de Macario, E. and Macario, A.J.L. (1986) Immunology of archaebacteria: Identification, antigenic relationships and immunochemistry of surface structures. Syst. Appl. Microbiol. 7, 320-324.
90. Mayerhofer, L.E., Macario, A.J.L. and Conway de Macario, E. (1992) Lamina, a novel multicellular form of Methanosarcina mazei S-6. J. Bacteriol. 174, 309-314.
91. Clarens, M., Cairó, J.J., París, J.M., Macario, A.J.L. and Conway de Macario, E. (1993) Characterization and forms of JC3, a new Methanosarcina isolate: Comparison with Methanosarcina mazei strains S-6T, MC3, and LYC. Curr. Microbiol. 26, 167-174.
92. Yao, R., Macario, A.J.L. and Conway de Macario, E. (1994) An archaeal S-layer gene homolog with repetitive subunits. Biochim. Biophys. Acta 1219, 697-700.
93. Bröckl, G., Behr, M., Fabry, S., Hensel, R., Kaudewitz, H., Biendl, E. and König, H. (1991) Analysis and nucleotide sequence of the genes encoding the surface-layer glycoproteins of the hyperthermophilic methanogens Methanothermus fervidus and Methanothermus sociabilis. Eur. J. Biochem. 199, 147-152.
94. Mayerhofer, L.E., Conway de Macario, E. and Macario, A.J.L. (1995) Conservation and variability in Archaea: Protein antigens with tandem repeats encoded by a cluster of genes with common motifs in Methanosarcina mazei S-6. Gene 165, 87-91.
95. Borst, P., Bitter, W., McCulloch, R., Van Leeuwen, F. and Rudenko, G. (1995) Antigenic variation in malaria. Cell 82, 1-4.
96. Dybvig, K. (1993) DNA rearrangements and phenotypic switching in prokaryotes. Mol. Microbiol. 10, 465-471.
97. Jovell, R.J., Macario, A.J.L. and Conway de Macario, E. (1996) ABC transporters in Archaea: Two genes encoding homologs of the nucleotide-binding components in the methanogen Methanosarcina mazei S-6. Gene 174, 281-284.
98. Jovell, R.J., Macario, A.J.L. and Conway de Macario, E. (1997) An ABC-transporter system homolog in an organism of the phylogenetic domain Archaea. DNA Sequence 7, 193-198.
99. Castón, J., Carrascosa, J., de Pedro, M.A. and Berenguer, J. (1988) Identification of a crystalline layer on the cell envelope of the thermophilic eubacterium Thermus thermophilus. FEMS Lett. 51, 225-230.
100. 2+-binding properties of the monomeric protein of the S-layer of Thermus thermophilus. FEBS Lett. 235, 117-121.
101. Faraldo, M.L.M., de Pedro, M.A. and Berenguer, J. (1991) Cloning and expression in Escherichia coli of the structural gene coding for the monomeric protein of the S-layer of Thermus thermophilus HB8. J. Bacteriol. 173, 5346-5351.
102. Faraldo, M.L.M., de Pedro, M.A. and Berenguer, J. (1992) Sequence of the S-layer gene of Thermus thermophilus HB8 and functionality of its promoter in Escherichia coli. J. Bacteriol. 174, 7458-7462.
103. Castón, J.R., Berenguer, J., de Pedro, M.A. and Carrascosa, J.L. (1993) The S-layer protein from Thermus thermophilus HB8 assembles into porin-like structures. Mol. Microbiol. 9, 65-75.
104. Castón, J.R., Berenguer, J., Kocsics, E. and Carrascosa, J.L. (1994) Three-dimensional structure of different aggregates built up by the S-layer protein of Thermus thermophilus. J. Struct. Biol. 113, 164-176.
105. Sleytr, U.B. (1978) Regular arrays of macromolecules on bacterial cell walls: structure, chemistry, assemble, and function. Int. Rev. Cytol. 53, 1-64.
106. Lasa, I., de Grado, M., de Pedro, M.A. and Berenguer, J. (1992) Development of Thermus-Escherichia shuttle vectors and their use for the expression in Thermus thermophilus of the celA gene from Clostridium thermocellum. J. Bacteriol. 174, 6424-6431.
107. Plumbridge, J.A., Cochet, O., Souza, J.M., Altamirano, M.M., Calgagno, M.L. and Badet, B. (1993) Coordinated regulation of animo sugar-synthesizing and -degrading enzymes in Escherichia coli K12. J. Bacteriol. 175, 4951-4956.
108. Fernández-Herrero, L.A., Badet-Denisot, M.A., Badet, B. and Berenguer, J. (1995) GlmS of Thermus thermophilus HB8: An essential gene for cell wall synthesis identified immediately upstream the S-layer gene. Mol. Microbiol. 17, 1-12.
109. Beck, C.F. and Warren, R.A.J. (1988) Divergent promoters, a common form of gene organization. Microbiol. Rev. 52, 318-326.
110. Lasa, I., Castón, J.R., Fernandez-Herrero, L.A., Pedro, M.A. and Berenguer, J. (1992) Insertional mutagenesis in the extreme thermophilic eubacteria Thermus thermophilus. Mol. Microbiol. 11, 1555-1564.
111. Henning, U. and Koebnik, R. (1994) Outer membrane proteins of Escherichia coli: mechanism of sorting and regulation of synthesis. In: Bacterial Cell Wall (Ghuysen, J.M. and Hakenbeck, R., Eds.), Vol. 27, pp. 381-395. Elsevier, London.
112. Fernández-Herrero, L.A. (1995) Caracterización de genes implicados en la regulación y la síntesis de la envoltura celular de T. thermophilus HB8. Universidad Autónoma de Madrid.
113. Fernández-Herrero, L.A., Olabarría, G. and Berenguer, J. (1997) Surface proteins and a novel transcription factor regulate the expression of the S-layer gene in Thermus thermophilus HB8. Mol. Microbiol. 24, 61-72.
114. Travers, A.A. (1991) DNA bending and kinking: sequence dependence and function. Curr. Opin. Struct. Biol. 1, 114-122.
115. Boot, H.J. and Pouwels, P.H. (1996) Expression, secretion and antigenic variation of bacterial S-layer proteins. Mol. Microbiol. 21, 1117-1123.
116. Boot, H.J., Kolen, C.P.A.M., Andreadaki, F.J., Leer, R.J. and Pouwels, P.H. (1996) The Lactobacillus acidophilus S-layer protein gene expression site comprises two consensus promoter sequences, one of which directs transcription of stable mRNA. J. Bacteriol. 178, 5388-5394.
117. Blaser, M.J. (1993) Role of the S-layer proteins of Campylobacter fetus in serum resistance and antigenic variation: a model of bacterial pathogenesis. Am. J. Med. Sci. 306, 325-329.
118. Blaser, M.J. and Pei, Z. (1993) Pathogenesis of Campylobacter fetus infections. Critical role of high molecular mass S-layer proteins in virulence. J. Infect. Dis. 167, 372-377.
119. Neuzil, K.M., Wang, E., Haas, D. and Blaser, M.J. (1994) Persistence of Campylobacter fetus bacteremia associated with absence of opsonizing antibodies. J. Clin. Microbiol. 32, 1718-1720.
120. Garcia, M.M., Lutze-Wallace, C.L., Azucena, S.D., Eaglesome, M.D., Holst, E. and Blaser, M.J. (1995) Protein shift and antigenic variation in the S-layer of Campylobacter fetus subsp. venerealis during bovine infection accompanied by genomic rearrangement of sapA homologs. J. Bacteriol. 177, 1976-1980.
121. Dworkin, J., Tummuru, M.K.R. and Blaser M.J. (1995) Segmental conservation of sapA sequences in type B Campylobacter fetus cells. J. Biol. Chem. 270, 15093-15101.
122. Tummuru, M.K.R. and Blaser, M.J. (1992) Characteristics of the Campylobacter fetus sapA promoter: evidence that the sapA promoter is deleted in spontaneous mutant strains. J. Bacteriol. 174, 5916-5922.
123. Dworkin, J., Tummuru, M.K.R. and Blaser, M.J. (1995) The lipopolysaccharide binding domain of the Campylobacter fetus S-layer protein resides within the conserved N-terminus of a family of silent and divergent homologs. J. Bacteriol. 177, 1734-1741.
124. Dworkin, J. and Blaser, M.J. (1997) Nested DNA inversion as a paradigm of programmed gene rearrangement. Proc. Natl. Acad. Sci. USA 94, 985-990.
125. Grogono-Thomas, R., Newell, D.G., Woodland, R.M. and Blaser, M.J. (1997) The role of S-layer proteins in ovine campylobacter abortion. FEMS Microbiol. Rev. (this issue).
126. Hollaus, F. (1969) Charakterisierung hochthermophiler Bacillus-Stämme aus Extraktionsanlagen von Rübenzuckerfabriken. Thesis, University of Agricultural Sciences, Vienna.
127. Messner, P., Hollaus, F. and Sleytr, U.B. (1984) Paracrystalline cell wall surface layers on different Bacillus stearothermophilus strains. Int. J. Syst. Bacteriol. 34, 202-210.
128. Sleytr, U.B., Sára, M., Küpcü, Z. and Messner, P. (1986) Structural and chemical characterization of S-layers of selected strains of Bacillus stearothermophilus and Desulfotomaculum nigrificans. Arch. Microbiol. 146, 19-24.
129. Bartelmus, W. and Perschak, F. (1957) Schnellmethode zur Keimzahlbestimmung in der Zuckerindustrie. Z. Zuckerind. 7, 276-281.
130. Schuster, K.C., Mayer, H.F., Kieweg, R., Hampel, W.A. and Sára, M. (1995) A synthetic medium for continuous culture of the S-layer carrying Bacillus stearothermophilus PV72 and studies on the influence of growth conditions on cell wall properties. Biotechnol. Bioeng. 48, 66-77.
131. Kuen, B., Sleytr, U.B. and Lubitz, W. (1994) Sequence analysis of the sbsA. gene encoding the 130 kDA surface layer protein of Bacillus stearothermophilus PV72. Gene 145, 115-120.
132. Kuen, B., Sára, M. and Lubitz, W. (1996) Heterologous expression and self-assembly of the S-layer protein SbsA of Bacillus stearothermophilus in Escherichia coli. Mol. Microbiol. 19, 495-503.
133. Breitwieser, A., Gruber, K. and Sleytr, U.B. (1992) Evidence for an S-layer protein pool in the peptidoglycan of Bacillus stearothermophilus. J. Bacteriol. 174, 8008-8015.
134. Sleytr, U.B. and Glauert, A.M. (1975) Analysis of regular arrays of subunits on bacterial surfaces: evidence for a dynamic process of assembly. J. Ultrastruct. Res. 50, 103-116.
135. Pink, T., Langer, K., Hotzy, C. and Sára, M. (1996) Regulation of S-layer protein synthesis of Bacillus stearothermophilus PV72 through variation of continuous cultivation conditions. J. Biotechnol. 50, 189-200.
136. Eder, J. (1983) Versuche zur Aufklärung der Funktion parakristalliner Proteinmembranen Bacillus stearothermophilus. Thesis, University of Agricultural Sciences, Vienna.
137. Schuster, K.C., Pink, T., Mayer, H.F., Hampel, W.A. and Sára, M. (1997) Oxygen-triggered synchronized variant formation of the S-layer carrying Bacillus stearothermophilus PV72 during continuous cultivation. J. Biotechnol. (in press).
138. Sára, M. and Sleytr, U.B. (1994) Comparative studies of S-layer proteins from Bacillus stearothermophilus strains expressed during growth in continuous culture under oxygen-limited and non oxygen-limited conditions. J. Bacteriol. 176, 7182-7189.
139. Kuen, B. and Lubitz, W. (1996) Analysis of S-layer proteins and genes. In: Crystalline Bacterial Cell Surface Proteins (Sleytr, U.B., Messner, P., Pum, D. and Sára, M., Eds.), pp. 77-102. Landes, Academic Press, Austin, TX.
140. Kuen, B., Koch, A., Asenbauer, E., Sára, M. and Lubitz, W. (1997) Molecular characterization of the Bacillus stearothermophilus PV72 S-layer gene sbsB induced by oxidative stress. J. Bacteriol. 179, 1664-1670.
141. Blaser, M. and Joel, D. (1996) Generation of Campylobacter fetus S-layer protein diversity utilizes a single promoter on an invertible DNA segment. Mol. Microbiol. 19, 1241-1253.
142. Plasterk, R.H.A., Simon, M.I. and Barbour, A.G. (1985) Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii. Nature 318, 257-263.
143. Rosa, P.A., Schwan, T. and Hogan, D. (1992) Recombination between genes encoding major outer surface proteins A and B of Borrelia burgdorferi. Mol. Microbiol. 6, 3031-3040.
144. McKay, L.L. and Baldwin, K.A., (1990) Applications for biotechnology: present and future improvements in lactic acid bacteria. FEMS Microbiol. Rev. 87, 3-14.
145. Perdigon, G., Medici, M., Bibas Bonet de Jorrat, M.E., Valverde de Budeguer, M. and Pesce de Ruiz Holgado, A. (1993) Immunomodulating effects of lactic acid bacteria on mucosal and tumoral immunity. Int. J. Immunother. 9, 29-52.
146. Kitazawa, H., Matsumura, K., Itoh, T. and Yamaguchi, T. (1992) Interferon induction in murine peritoneal macrophage by stimulation with Lactobacillus acidophilus. Microbiol. Immunol. 36, 311-315.
147. Fernandes, C.F., Shahani, K.M. and Amer, M.A. (1987) Therapeutic role of dietary lactobacilli and lactobacillic fermented dairy products. FEMS Microbiol. Rev. 46, 343-356.
148. Coconnier, M.-H., Bernet, M.-F., Kerneis, S., Chauviere, G., Fourniat, J. and Servin, A.L. (1993) Inhibition of adhesion of enteroinvasive pathogens to human intestinal Caco-2 cells by Lactobacillus acidophilus strain LB decreases bacterial invasion. FEMS Microbiol. Lett. 110, 299-306.
149. Beachey, E.H. (1981) Bacterial adherence: Adhesin-receptor interactions mediating the attachment of bacteria to mucosal surfaces. J. Infect. Dis. 143, 325-345.
150. Masuda, K. and Kawata, T. (1983) Distribution and chemical characterization of regular arrays in the cell walls of strains of the genus Lactobacillus. FEMS Microbiol. Lett. 20, 145-150.
151. Ray, B. and Johnson, M.C. (1986) Freeze-drying injury of surface layer protein and its protection in Lactobacillus acidophilus. Cryo-Letters 7, 210-217.
152. Lortal, S. (1993) Crystalline surface layers of the genus Lactobacillus. In: Advances in Paracrystalline Bacterial Surface Layers (Beveridge, T.J. and Koval, S.F., Eds.), pp. 57-65. Plenum, New York.
153. Mukai, T. and Arihara, K. (1994) Presence of intestinal lectin-binding glycoproteins on the cell surface of Lactobacillus acidophilus. Biosci. Biotech. Biochem. 58, 1851-1854.
154. Schneitz, C., Nuotio, L. and Lounatma, K. (1993) Adhesion of Lactobacillus acidophilus to avian intestinal epithelial cells mediated by the crystalline bacterial cell surface layer (S-layer) J. Appl. Bacteriol. 74, 290-294.
155. Greene, J.D. and Klaenhammer, T.R. (1994) Factors involved in adherence of lactobacilli to human Caco-2 cells. Appl. Environ. Microbiol. 60, 4487-4494.
156. Boot, H.J., Kolen, C.P.A.M., van Noort, J.M. and Pouwels, P.H. (1993) S-layer protein of Lactobacillus acidophilus ATCC 4356: purification, expression in Escherichia coli, and nucleotide sequence of the corresponding gene. J. Bacteriol. 175, 6089-6096.
157. Boot, H.J., Kolen, C.P.A.M. and Pouwels, P.H. (1995) Identification, cloning and nucleotide sequence of a silent S-layer protein gene of Lactobacillus acidophilus 4356 which has extensive similarity with the S-layer protein gene of this species. J. Bacteriol. 177, 7222-7230.
158. Vidgren, G., Palva, I., Pakkanen, R., Lounatmaa, K. and Palva, A. (1992) S-layer protein gene of Lactobacillus brevis: cloning by polymerase chain reaction and determination of the nucleotide sequence. J. Bacteriol. 174, 7419-7427.
159. Pouwels, P.H. and Leunissen, J.A.M. (1994) Divergence in codon usage of Lactobacillus species. Nucleic Acids Res. 22, 929-936.
160. Boot, H.J., Kolen, C.P.A.M., Pot, B., Kersters, K. and Pouwels, P.H. (1996) The presence of two S-layer protein encoding genes is conserved among species related to Lactobacillus acidophilus. Microbiology 142, 2375-2384.
161. Hellmann, C., Schweitzer, O., Gerke, C., Vanittanakom, N., Mack, D. and Gotz, F. (1996) Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis. Mol. Microbiol. 20, 1083-1091.
162. Pendrak, M.L. and Perry, R.D. (1993) Proteins essential for expression of the Hms+ phenotype of Yersinia pestis. Mol. Microbiol. 8, 857-864.
163. Hinnebusch, B.J., Perry, R.D. and Schwan, T.G. (1996) Role of the Yersinia pestis hemin storage (hms) locus in the transmission of plague by fleas. Science 273, 367-370.
164. Noonan, B. and Trust, T.J. (1995) The leucine zipper of Aeromonas salmonicida AbcA is required for the transcriptional activation of the P2 promoter of the surface-layer structural gene, vapA, in Escherichia coli. Mol. Microbiol. 17, 379-386.
165. Bowditch, R.D., Baumann, P. and Yousten, A.A. (1989) Cloning and sequencing of the gene encoding a 125-kilodalton surface-layer protein from Bacillus sphaericus 2362 and of a related cryptic gene. J. Bacteriol. 171, 4178-4188.
166. Matern, H.T., Klein, J.R., Henrich, B. and Plapp, R. (1994) Determination and comparison of Lactobacillus delbrueckii ssp. lactis DSM7290 promoter sequences. FEMS Microbiol. Lett. 122, 121-128.
167. Boot, H.J. (1996) The surface layer protein genes of Lactobacillus acidophilus. Thesis, University of Amsterdam, Amsterdam.
168. Masuda, K. and Kawata, T. (1980) Reassembly of the regularly arranged subunits in the cell wall of Lactobacillus brevis and their reattachment to cell walls. Microbiol. Immunol. 24, 299-308.
169. Feng, J.-A., Johnson, R.C. and Dickerson, R.E. (1994) Hin recombinase bound to DNA: the origin of specificity in major and minor groove interactions. Science 263, 348-355.
170. Toba, T., Virkola, R., Westerlund, B., Bjorkman, Y., Sillanpaa, J., Vartio, T., Kalkkinen, N. and Korhonen, T.K. (1995) A collagen-binding S-layer protein in Lactobacillus crispatus. Appl. Environ. Microbiol. 61, 2467-2471.
171. Pouwels, P.H., Leer, R.J. and Boersma, W.J.A. (1996) The potential of Lactobacillus as a carrier for oral immunization: development and preliminary characterization of vector systems for targeted delivery of antigens. J. Biotechnol. 44, 183-192.
172. Sleytr, U.B. and Messner, P. (1988) Crystalline surface layers in prokaryotes. J. Bacteriol. 170, 2891-2897.
173. Board, R.G., Jones, D. and Jarvis, B. (1995) Microbial Fermentations: Beverages, Foods, and Feeds. Society for Applied Bacteriology Symposium Series Number 24. Suppl. to J. Appl. Bacteriol. Vol. 79. Blackwell Science, Oxford.
174. Wood, J.B. (Ed.) (1992) The Lactic Acid Bacteria in Health and Disease. Elsevier, Amsterdam.
175. Masuda, K. and Kawata, T. (1979) Ultrastructure and partial characterization of regular array in the cell wall of Lactobacillus brevis. Microbiol. Immunol. 23, 941-953.
176. Palva, A., Vidgren, G., Palva, I., Pakkanen, R. and Lounatmaa, K. (1992) Characterization of expression and secretion signals from Lactobacillus brevis for use in food and feed industry. In: Proceedings of Sixth Forum for Applied Biotechnology. Med. Fac. Landbouwwetensch. Univ. Gent, 57/4b, 1891-1898.
177. Von Heijne, G. (1985) Signal sequences: The limits of variation. J. Mol. Biol. 184, 99-105.
178. Von Heijne, G. (1987) Sequence Analysis in Molecular Biology. Academic Press, New York.
179. Shields, D.C. and Sharp, P.M. (1987) Synonymous codon usage in Bacillus subtilis reflects both translational selection and mutational biases. Nucleic Acids Res. 15, 8023-8040.
180. Smit, J. (1986) Protein surface layers of bacteria. In Bacterial Outer Membranes as Model Systems (Inouye, M., Ed.), pp. 343-376. John Wiley and Sons, New York.
181. Kahala, M., Savijoki, K. and Palva, A. (1997) In vivo expression of the Lactobacillus brevis S-layer gene. J. Bacteriol. 179, 284-286.
182. Chu, S., Gustafson, C.E., Feutrier, J., Cavaignac, S. and Trust, T.J. (1993) Transcriptional analysis of the Aeromonas salmonidica S-layer protein gene vapA. J. Bacteriol. 175, 7968-7975.
183. Ebisu, S., Tsuboi, A., Takagi, H., Naruse, Y., Yamagata, H., Tsukagoshi, N. and Udaka, S. (1990) Conserved structures of cell wall protein genes among protein-producing Bacillus brevis strains. J. Bacteriol. 172, 1312-1320.
184. Kok, J., van der Vossen, M.B.M. and Venema, G. (1984) Construction of plasmid cloning vectors for lactic streptococci which also replicate in Bacillus subtilis and Escherichia coli. Appl. Environ. Microbiol. 48, 726-731.
185. Savijoki, K., Kahala, M. and Palva, A. (1997) High level heterologous protein production in Lactococcus and Lactobacillus using a new secretion system based on the Lactobacillus brevis S-layer signals. Gene 186, 255-262.
186. Koivula, T., Sibakov, M. and Palva, I. (1991) Isolation and characterization of Lactococcus lactis subsp. lactis promoters. Appl. Environ. Microbiol. 57, 333-340.
187. Sibakov, M., Koivula, T., von Wright, A. and Palva, I. (1991) Secretion of TEM β-lactamase with signal sequences isolated from the chromosome of Lactococcus lactis subsp. lactis. Appl. Environ. Microbiol. 57, 341-348.
188. Sára, M., Küpcü, S. and Sleytr, U.B. (1996) Biotechnological applications of S-layers. In : Crystalline Bacterial Cell Surface Proteins (Sleytr, U.B., Messner, P., Pum, D. and Sára, M., Eds.), pp. 133-160. Landes, Academic Press, Austin, TX.
189. Pum, D., Sára, M. and Sleytr, U.B. (1989) Structure, surface charge and self-assembly of the S-layer lattice from Bacillus coagulans E38-66. J. Bacteriol. 171, 5296-303.
190. Sára, M. and Sleytr, U.B. (1987) Charge distribution on the S-layer of Bacillus stearothermophilus NRS 1536/3c and the importance of charged groups for morphogenesis and function. J. Bacteriol. 169, 2804-2809.
191. Sára, M. and Sleytr, U.B. (1993) Relevance of charged groups for the integrity of the layer from Bacillus coagulans E38-66 and for molecular interactions. J. Bacteriol. 175, 2248-2254.
192. Sleytr, U.B., Messner, P., Pum, D. and Sára, M. (1996) Occurrence, location, ultrastructure and morphogenesis of S-layers. In: Crystalline Bacterial Cell Surface Proteins (Sleytr, U.B., Messner, P., Pum, D. and Sára, M., Eds.), pp. 5-34. Landes, Academic Press, Austin, TX.
193. Kim, L., Mogk, A. and Schumann, W. (1996) A xylose-inducible Bacillus subtilis integration vector and its application. Gene 181, 71-76.
194. Chen, W.J., Gross, L., Joho, K.E. and McAllister, W.T. (1992) A modified kanamycin-resistance cassette to facilitate two-codon insertion mutagenesis. Gene 111, 143-144.
195. Breiteneder, H., Pettenburger, K., Bito A., Valenta, R., Kraft, D., Rumpold, H. and Breitenbach, M. (1989) The gene coding for the major birch pollen allergen Bet v 1, is highly homologous to a pea disease response gene. EMBO J. 8, 1935-1938.
196. Ferreira, F.D., Hoffmann-Sommergruber, K., Breiteneder, H., Pettenburger, K., Ebner, C., Sommergruber, W., Steiner, R., Bohle, B., Sperr, W.R., Valent, P., Kungl, A.J., Breitenbach, M., Kraft, D. and Schreiner, O. (1993) Purification and characterization of recombinant Bet v 1, the major birch pollen allergen. Immunological equivalence to natural Bet v 1. J. Biol. Chem. 268, 19574-19580.
197. Mettenleiter, T.C. (1994) Pseudorabies (Aujesky's disease) virus: state of the art, August 1993. Acta Vet. Hung. 42, 153-177.
198. Janes, B., Hollar, J. and Dennis, D. (1990) Molecular characterisation of the poly-β-hydroxy-butyrate biosynthesis in Alcaligenes eutrophus H16. In: Novel Biodegradable Microbial Polymers (Dawes, E.A., Ed.), pp. 175-190. Kluwer, Dordrecht.
199. Kalousek, S., Dennis, D. and Lubitz, W. (1993) Genetic engineering of PHB-synthase from Alcaligenes eutrophus H16. In: Proceedings of the International Symposium on Bacterial Polyhydroxy-alkanoates. (Schlegel, H.G. and Steinbüchel, A., Eds.), pp. 426-427. Goltze, Göttingen.