Na+/K+ ATPase mediates rhythmic spontaneous relaxations in canine airway smooth muscle

Respiration Physiology

Volumn 108, Issue 2, 1997, Pages 187-194

  Janssen, Luke J ^a   Nana, Roopung ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Airway smooth muscle; Airways; Ca2+ ATPase; Ca2+ dependent; Dog; Ion channels; K+; Mammals; Smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARBACHOL; CYCLOPIAZONIC ACID; DIHYDROPYRIDINE DERIVATIVE; INDOMETACIN; ION CHANNEL; OUABAIN; POTASSIUM CHANNEL;

AIRWAY CONSTRICTION; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; ENZYME ACTIVITY; MEMBRANE DEPOLARIZATION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; MUSCLE RELAXATION; MUSCLE, SMOOTH; NA(+)-K(+)-EXCHANGING ATPASE; RESPIRATORY MUSCLES; VASODILATOR AGENTS;

EID: 0031149773     PISSN: 00345687     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5687(97)00023-6     Document Type: Article

References (16)

1. Bose R., Bose D. Excitation-contraction coupling in multiunit tracheal smooth muscle during metabolic depletion: induction of rhythmicity. Am. J. Physiol. 233:1977;C8-C13.
2. 2+ stores in canine airway smooth muscle. Am. J. Physiol. 265:1993;C28-C35.
3. +-pump in smooth muscle: physiologic and pharmacologic significance. Ann. Rev. Pharmacol. Toxicol. 20:1980;129-149.
4. Gunst S.J., Stropp J.Q. Effect of Na-K adenosinetriphosphatase activity on relaxation of canine tracheal smooth muscle. J. Appl. Physiol. 64:1988;635-641.
5. 2+ store in tracheal myocytes as indicated by ACh-evoked currents and contraction. Am. J. Physiol. 265:1993;C877-C886.
6. 2+ exchange mechanisms. Am. J. Respir. Clin. Care Med. 151:1995;A181.
7. + channels. J. Pharmacol. Exp. Ther. 279:1996;813-821.
8. Kong S.-K., Stephens N.L. Induction of rhythmic contraction in canine tracheal smooth muscle. Can. J. Physiol. Pharmacol. 68:1990;1313-1316.
9. Morrison K.J., Vanhoutte P.M. Stimulation of sodium pump by vasoactive intestinal peptide in guinea-pig isolated trachea: potential contribution to mechanisms underlying relaxation of smooth muscle. Br. J. Pharmacol. 118:1996;557-562.
10. +-pumping in guinea-pig isolated trachealis: their modulation by the epithelium. Br. J. Pharmacol. 98:1989;343-350.
11. +-ATPase. Br. J. Pharmacol. 99:1990;237-242.
12. 2+-ATPase of sarcoplasmic reticulum. J. Biol. Chem. 264:1989;17816-17823.
13. Souhrada, M., Souhrada, J.F., 1994. Immunological changes of airway smooth muscle reactivity. In: Raeburn, D., Giembycz, M.A. (Eds.), Airways smooth muscle: development and regulation of contractility. Birkhauser Verlag, Basel Switzerland, pp. 219-258.
14. Souhrada M., Souhrada J.F., Cherniack R.M. Evidence for a sodium electrogenic pump in airway smooth muscle. J. Appl. Physiol. 51:1981;346-352.
15. Spina, D., 1994. Epithelium-dependent regulation of airways smooth muscle tone. In: Raeburn, D., Giembycz, M.A. (Eds.), Airways smooth muscle: development and regulation of contractility. Birkhauser Verlag, Basel Switzerland, pp. 259-289.
16. Tamaoki J., Chiyotani A., Takeyama K., Yamauchi F., Tagaya E., Konno K. Relaxation and inhibition of contractile response to electridal field stimulation by beraprost sodium in canine airway smooth muscle. Prostaglandins. 45:1993;363-373.